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158 条记录 (耗时 0.246 秒)

    Device and Method for Modifying the Shape of a Body Organ
    61.
    发明申请
    Device and Method for Modifying the Shape of a Body Organ 审中-公开
    修饰身体器官形状的装置和方法

    公开(公告)号：US20120197389A1

    公开(公告)日：2012-08-02

    申请号：US13443709

    申请日：2012-04-10

    申请人： Clifton A. Alferness ,  John M. Adams ,  Mark L. Mathis ,  David G. Reuter ,  Cruz Beeson ,  Leonard Kowalsky

    发明人： Clifton A. Alferness ,  John M. Adams ,  Mark L. Mathis ,  David G. Reuter ,  Cruz Beeson ,  Leonard Kowalsky

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2451 ,  A61F2250/001 ,  A61F2250/0059

    摘要： An intravascular support device includes a support or reshaper wire, a proximal anchor and a distal anchor. The support wire engages a vessel wall to change the shape of tissue adjacent the vessel in which the intravascular support is placed. The anchors and support wire are designed such that the vessel in which the support is placed remains open and can be accessed by other devices if necessary. The device provides a minimal metal surface area to blood flowing within the vessel to limit the creation of thrombosis. The anchors can be locked in place to secure the support within the vessel.

    摘要翻译： 血管内支持装置包括支撑件或再生线，近端锚和远端锚。 支撑线接合血管壁以改变邻近其中放置血管内支架的血管的组织的形状。 锚和支撑线被设计成使得放置支撑件的容器保持打开，并且如果需要可以被其他装置访问。 该装置为在血管内流动的血液提供最小的金属表面积，以限制血栓形成。 锚固件可以锁定到位以将支撑件固定在容器内。

    Removable anchored lung volume reduction devices and methods
    63.
    发明授权
    Removable anchored lung volume reduction devices and methods 有权
    可拆卸锚固肺体积减少装置及方法

    公开(公告)号：US08021385B2

    公开(公告)日：2011-09-20

    申请号：US11880090

    申请日：2007-07-19

    申请人： Clifton A. Alferness

    发明人： Clifton A. Alferness

    IPC分类号： A61M29/00

    CPC分类号： A61B17/12104 ,  A61B17/12022 ,  A61B17/1204 ,  A61B17/12159 ,  A61B17/12172 ,  A61B2017/1205 ,  A61B2017/22051 ,  A61B2017/22067 ,  A61F2002/043

    摘要： A method for treating a lung using an intra-bronchial device may be placed and anchored in an air passageway of a patient to collapse a lung portion associated with the air passageway. The method includes using an obstructing member that prevents air from being inhaled into the lung portion, and an anchor that anchors the obstruction device within the air passageway. The anchor may piercingly engage the air passageway wall. The anchor may be releasable from the air passageway for removal of the obstructing member. The anchor may be releasable by collapsing a portion of the obstructing member, or by drawing the obstructing member toward the larynx. The obstructing member may be a one-way valve.

    摘要翻译： 可以将使用支气管内装置治疗肺的方法放置并锚定在患者的空气通道中以折叠与空气通道相关联的肺部分。 该方法包括使用防止空气被吸入肺部的阻塞构件，以及将阻塞装置固定在空气通道内的锚固件。 锚固件可以穿透空气通道壁。 锚固件可以从空气通道释放以去除阻塞构件。 锚固件可以通过塌缩阻塞构件的一部分，或者通过将阻塞构件拉向喉部来释放。 阻塞构件可以是单向阀。

    ONE-WAY VALVE DEVICES FOR ANCHORED IMPLANTATION IN A LUNG
    65.
    发明申请
    ONE-WAY VALVE DEVICES FOR ANCHORED IMPLANTATION IN A LUNG 有权
    用于在肺中锚固植入的单向阀装置

    公开(公告)号：US20110079221A1

    公开(公告)日：2011-04-07

    申请号：US12968771

    申请日：2010-12-15

    申请人： David H. Dillard ,  Hugo X. Gonzalez ,  Seung Yi ,  Lauri J. DeVore ,  Mia Park ,  Dean T. Corcoran ,  Jenni Rimbaugh ,  Clifton A. Alferness

    发明人： David H. Dillard ,  Hugo X. Gonzalez ,  Seung Yi ,  Lauri J. DeVore ,  Mia Park ,  Dean T. Corcoran ,  Jenni Rimbaugh ,  Clifton A. Alferness

    IPC分类号： A61M16/00

    CPC分类号： A61B17/12104 ,  A61B17/12172 ,  A61B2017/00809 ,  A61F2/24 ,  A61F2002/043

    摘要： An intra-bronchial device placed and anchored in an air passageway of a patient to collapse a lung portion associated with the air passageway. The device includes a support structure, an obstructing member carried by the support structure that reduces ventilation to the lung portion by preventing air from being inhaled into the lung portion, and at least one anchor carried by the support structure that anchors the obstruction device within the air passageway. The anchor may engage the air passageway wall by piercing or friction, include a stop dimensioned for limiting the piercing of the air passageway wall, and may be releasable from the air passageway for removal of the intra-bronchial device. The anchors may be carried by a peripheral portion of the support structure, or by a central portion of the support structure. The obstructing member may be a one-way valve.

    摘要翻译： 将支气管内装置放置并锚定在患者的空气通道中以折叠与空气通道相关联的肺部分。 该装置包括支撑结构，由支撑结构承载的阻塞构件，其通过防止空气被吸入肺部而减少对肺部的通气，以及由支撑结构承载的至少一个锚固件，其将阻塞装置锚定在内部 空气通道。 锚固件可以通过穿孔或摩擦接合空气通道壁，包括尺寸适于限制空气通道壁的刺穿的止挡件，并且可以从空气通道释放以去除支气管内装置。 锚固件可以由支撑结构的周边部分或支撑结构的中心部分承载。 阻塞构件可以是单向阀。

    COMPUTER-IMPLEMENTED METHOD FOR PROVIDING A PERSONALIZED TOOL FOR ESTIMATING 1,5-ANHYDROGLUCITOL
    66.
    发明申请
    COMPUTER-IMPLEMENTED METHOD FOR PROVIDING A PERSONALIZED TOOL FOR ESTIMATING 1,5-ANHYDROGLUCITOL 审中-公开
    用于提供个体化工具的计算机实现方法，用于估算1,5-ANHYDROGLUCITOL

    公开(公告)号：US20110077930A1

    公开(公告)日：2011-03-31

    申请号：US12894031

    申请日：2010-09-29

    申请人： Clifton A. Alferness ,  Gust H. Bardy

    发明人： Clifton A. Alferness ,  Gust H. Bardy

    IPC分类号： G06G7/60 ,  G01N33/48 ,  G06F19/00

    CPC分类号： G06F19/3456 ,  G16H15/00 ,  G16H50/50

    摘要： A computer-implemented method for providing a personalized tool for estimating 1,5-anhydroglucitol is provided. An electronically-stored history of empirically measured glucose levels is maintained for a patient over a set period of time in order of increasing age. A predictive model of estimated glycated hemoglobin is built on a computer workstation. A decay factor is designated particularized to the patient. The decay factor is applied to each of the measured glucose levels. The measured glucose levels is scaled by a scaling coefficient. The measured glucose levels are aggregated and scaled as decayed and scaled into an estimate of glycated hemoglobin for the time period. The glycated hemoglobin estimate is displayed to the patient on the computer workstation.

    摘要翻译： 提供了一种用于提供用于估计1,5-脱水葡萄糖醇的个性化工具的计算机实现的方法。 根据年龄的增加，在一段时间内为患者维持经验测量的葡萄糖水平的电子存储历史。 估计糖化血红蛋白的预测模型建立在计算机工作站上。 衰减因子被指定为患者特定的。 衰减因子被应用于每个测量的葡萄糖水平。 测量的葡萄糖水平通过缩放系数缩放。 测量的葡萄糖水平被聚集并按比例衰变并且缩放到糖化血红蛋白的时间期间的估计值。 糖化血红蛋白估计显示给计算机工作站上的患者。

    REMOVABLE LUNG REDUCTION DEVICES, SYSTEMS, AND METHODS
    67.
    发明申请
    REMOVABLE LUNG REDUCTION DEVICES, SYSTEMS, AND METHODS 有权
    可拆卸的肺减少装置，系统和方法

    公开(公告)号：US20110054632A1

    公开(公告)日：2011-03-03

    申请号：US12828629

    申请日：2010-07-01

    申请人： Clifton A. Alferness ,  Hugo X. Gonzalez ,  David H. Dillard

    发明人： Clifton A. Alferness ,  Hugo X. Gonzalez ,  David H. Dillard

    IPC分类号： A61F2/04

    CPC分类号： A61B17/12104 ,  A61B17/12022 ,  A61B17/12036 ,  A61B17/12172 ,  A61B2017/1205 ,  A61B2017/12054 ,  A61F2002/043 ,  A61M16/0404

    摘要： An air passageway obstruction device includes a frame structure and a flexible membrane overlying the frame structure. The frame structure is collapsible upon advancement of the device into the air passageway, expandable into a rigid structure upon deploying in the air passageway and recollapsible upon removal from the air passageway. The flexible membrane obstructs inhaled air flow into a lung portion communicating with the air passageway. The device may be removed after deployment in an air passageway by recollapsing the device and pulling the device proximally through a catheter.

    摘要翻译： 空气通道阻塞装置包括框架结构和覆盖框架结构的柔性膜。 框架结构在装置进入空气通道中时可折叠，在展开在空气通道中时可扩展成刚性结构，并且在从空气通道移除时可重新收起。 柔性膜阻碍吸入的空气流入与空气通道连通的肺部分。 通过重新装回装置并将装置向近侧拉动通过导管，装置可以在部署在空气通道中之后被移除。

    SYSTEM AND METHOD FOR ACTIVELY MANAGING TYPE 2 DIABETES MELLITUS ON A PERSONALIZED BASIS
    69.
    发明申请
    SYSTEM AND METHOD FOR ACTIVELY MANAGING TYPE 2 DIABETES MELLITUS ON A PERSONALIZED BASIS 审中-公开
    在个人化基础上进行2型糖尿病管理的系统与方法

    公开(公告)号：US20100138203A1

    公开(公告)日：2010-06-03

    申请号：US12030097

    申请日：2008-02-12

    申请人： Clifton A. Alferness ,  Gust H. Bardy

    发明人： Clifton A. Alferness ,  Gust H. Bardy

    IPC分类号： G06G7/48 ,  A61B5/00

    CPC分类号： G06F19/3456 ,  G06F19/3475 ,  G06F19/3481 ,  G16H15/00 ,  G16H50/50

    摘要： A system and method for actively managing Type 2 diabetes mellitus on a personalized basis is provided. A model of glycemic effect for a Type 2 diabetic patient for digestive response is established. The digestive response model is adjusted for a degree of insulin resistance experienced by the patient. A rise in postprandial blood glucose through food ingestion of a planned meal is estimated in proportion to the adjusted digestive response model. The tool also allows for the avoidance of hypoglycemic episodes by medications.

    摘要翻译： 提供了一种以个性化方式主动管理2型糖尿病的系统和方法。 建立了2型糖尿病患者消化反应的血糖效应模型。 消化反应模型根据患者经历的胰岛素抵抗程度进行调整。 通过食物摄入计划用餐，餐后血糖升高与调整后的消化反应模型成比例。 该工具还允许通过药物避免低血糖发作。

    Disposable infusion device facilitating tissue fold formation for cannula deployment and method
    70.
    发明授权
    Disposable infusion device facilitating tissue fold formation for cannula deployment and method 有权
    一次性输液装置促进组织折叠形成用于插管部署和方法

    公开(公告)号：US07713258B2

    公开(公告)日：2010-05-11

    申请号：US12205655

    申请日：2008-09-05

    申请人： John M. Adams ,  Clifton A. Alferness

    发明人： John M. Adams ,  Clifton A. Alferness

    IPC分类号： A61M31/00

    CPC分类号： A61M5/14248 ,  A61M5/425 ,  A61M2005/1405 ,  A61M2005/1585

    摘要： A device and method facilitates the forming of a skin fold during deployment of a cannula. The device may be a disposable infusion device and the method comprises adhering, to a skin surface, a base member having a port for receiving a cannula, forming a skin fold having skin surfaces sloping away from opposite sides of the base member, driving a cannula through the port of the base member while maintaining the skin fold, and releasing the skin fold. To facilitate the forming of the skin fold, the device comprises a base having a base surface and a flexible layer member. The flexible layer member has a first surface adjacent the base surface and a second surface adapted to be adhered to a patient's skin. The first surface has a first portion adhered to a portion of the base surface and a second portion adherable to the base surface.

    摘要翻译： 装置和方法有助于在插管期间形成皮肤褶皱。 该装置可以是一次性输注装置，并且该方法包括将具有用于接收套管的端口的基部构件粘附到皮肤表面，形成具有从基部构件的相对侧倾斜的皮肤表面的皮肤褶皱，驱动套管 通过基底构件的端口，同时保持皮肤折叠，并释放皮肤褶皱。 为了促进皮肤褶皱的形成，该装置包括具有基底表面和柔性层部件的基部。 柔性层构件具有邻近基底表面的第一表面和适于粘附到患者皮肤的第二表面。 第一表面具有粘附到基部表面的一部分的第一部分和可粘附到基底表面的第二部分。