公开(公告)号：US20060247520A1

公开(公告)日：2006-11-02

申请号：US11117021

申请日：2005-04-28

申请人： David McGee

发明人： David McGee

IPC分类号： A61M25/00

CPC分类号： A61B6/487 ,  A61B5/06 ,  A61B5/062 ,  A61B5/063 ,  A61B5/068 ,  A61B6/12 ,  A61B6/4441 ,  A61B34/20 ,  A61B90/36 ,  A61B2034/2051 ,  A61B2034/2059 ,  A61B2090/376 ,  A61B2090/3954

摘要： Methods and systems for navigating medical devices are provided. A patient is imaged while a medical device is moved within the patient. A position (e.g., a location and/or orientation) of the moving medical device is detected within a coordinate system (e.g., a three-dimensional coordinate system), a position of the imaging field of view relative to the patient is adjusted based on the detected medical device position, such that the relevant tissue region of the patient is within the field of view. For example, the field of view can be centered over the medical device or centered just distal to the medical device portion. The direction of view may be oriented at an angle perpendicular to the axis of the medical device, e.g., for more accurately measuring the length of objects within the field of view, or oriented at an angle parallel to the axis of the medical device portion, e.g., for more accurately measuring the diameter of the channel (e.g., blood vessel) in which the medical device is disposed.

摘要翻译： 提供了导航医疗设备的方法和系统。 当医疗装置在患者体内移动时，患者被成像。 在坐标系（例如，三维坐标系）内检测到移动的医疗装置的位置（例如，位置和/或取向），基于相对于患者的成像视场的位置被调整 检测到的医疗装置位置，使得患者的相关组织区域在视野内。 例如，视野可以在医疗装置上居中或者位于医疗器械部分的远侧。 视图的方向可以以垂直于医疗装置的轴线的角度定向，例如，为了更精确地测量视场内的物体的长度或者以平行于医疗装置部分的轴线的角度定向， 例如，用于更精确地测量其中设置医疗装置的通道（例如，血管）的直径。

公开(公告)号：US20060196682A1

公开(公告)日：2006-09-07

申请号：US11070821

申请日：2005-03-03

申请人： David McGee ,  Daniel Burgjohann ,  Prudencio Canlas ,  Alexander Calvino ,  Jonathan Fairbanks

发明人： David McGee ,  Daniel Burgjohann ,  Prudencio Canlas ,  Alexander Calvino ,  Jonathan Fairbanks

IPC分类号： B25C5/06

CPC分类号： B25C1/188 ,  B25C1/041

摘要： A fastener driving device for use in driving a fastener into an elongated contoured portion of a workpiece is disclosed. The elongated contoured portion has a surface that is contoured perpendicular to a longitudinal direction of the elongated contoured portion. The device includes a contact arm that is operatively connected with the trigger assembly, and a contoured contact foot for engaging the workpiece. The contact arm is constructed and arranged to move relative to a housing assembly of the driving device when the contact foot is pressed against the workpiece. The contact foot has a contoured engaging surface that includes a recess that is shaped to generally complement the shape of the contoured surface of the workpiece.

摘要翻译： 公开了用于将紧固件驱动到工件的细长轮廓部分中的紧固件驱动装置。 细长轮廓部分具有垂直于细长轮廓部分的纵向的轮廓的表面。 该装置包括与触发器组件可操作地连接的接触臂和用于接合工件的成型接触脚。 接触臂被构造和布置成当接触脚压在工件上时相对于驱动装置的壳体组件移动。 接触脚具有轮廓的接合表面，该接合表面包括凹陷，凹部被成形为大体上与工件的轮廓表面的形状相互补充。

公开(公告)号：US20050005319A1

公开(公告)日：2005-01-06

申请号：US10893056

申请日：2004-07-16

申请人： Guy della-Cioppa ,  Robert Erwin ,  Wayne Fitzmaurice ,  Kathleen Hanley ,  Moaro Kumagai ,  John Lindbo ,  David McGee ,  Hal Padgett ,  Gregory Pogue

发明人： Guy della-Cioppa ,  Robert Erwin ,  Wayne Fitzmaurice ,  Kathleen Hanley ,  Moaro Kumagai ,  John Lindbo ,  David McGee ,  Hal Padgett ,  Gregory Pogue

IPC分类号： A01H1/04 ,  A01H5/12 ,  C12N15/10 ,  C12N15/83 ,  C12Q1/68 ,  A01H1/00 ,  C12N15/82 ,  C12N15/87

CPC分类号： C12N15/1079 ,  A01H1/04 ,  A01H5/12 ,  C12N15/1034 ,  C12Q1/68

摘要： The present invention provides methods for rapidly determining the function of nucleic acid sequences by transfecting the same into a host organism to effect expression. Phenotypic and biochemical changes produced thereby are then analyzed to ascertain the function of the nucleic acids which have been transfected into the host organism. The invention also provides methods for silencing endogenous genes by transfecting hosts with nucleic acid sequences to effect expression of the same. The present invention also provides methods for selecting desired functions of RNAs and proteins by the use of virus vectors to express libraries of nucleic acid sequence variants. Moreover, the present invention provides methods for inhibiting an endogenous protease of a plant host.

摘要翻译： 本发明提供了通过将其转染宿主生物来进行表达来快速测定核酸序列的功能的方法。 然后分析由此产生的表型和生物化学变化以确定已经转染到宿主生物体中的核酸的功能。 本发明还提供了通过用核酸序列转染宿主以使其表达而沉默内源基因的方法。 本发明还提供了通过使用病毒载体来表达核酸序列变体文库来选择RNA和蛋白质的所需功能的方法。 此外，本发明提供了抑制植物宿主的内源性蛋白酶的方法。

公开(公告)号：US06445346B2

公开(公告)日：2002-09-03

申请号：US09845095

申请日：2001-04-27

申请人： Aly E. Fathy ,  Louis S. Napoli ,  Francis J. McGinty ,  David McGee

发明人： Aly E. Fathy ,  Louis S. Napoli ,  Francis J. McGinty ,  David McGee

IPC分类号： H01Q138

CPC分类号： H01Q21/24 ,  H01Q21/0006

摘要： A planar polarizer feed network comprising a six port branch coupler having two input ports and four output ports. The output ports are designed to have the same amplitude while their phases are sequentially offset by 90 degrees when fed from a first input port or by minus 90 degrees when fed from a second input port. In one embodiment, each output port is coupled to an aperture coupled antenna array comprising four slots and four patch antenna elements. In this arrangement, an RF signal may be coupled to each of the two input ports to couple properly phased signals to each of the antenna elements to simultaneously form both right-hand and left-hand circularly polarized signal emitted from the planar array of antenna elements.

摘要翻译： 一种平面偏振器馈电网络，包括具有两个输入端口和四个输出端口的六端口分支耦合器。 输出端口被设计为具有相同的幅度，而当从第一输入端口馈送时，它们的相位顺序地偏移90度，或者当从第二输入端口馈送时相位相差90度。 在一个实施例中，每个输出端口耦合到包括四个插槽和四个贴片天线元件的孔耦合天线阵列。 在这种布置中，RF信号可以耦合到两个输入端口中的每一个，以将适当的相位信号耦合到每个天线元件，以同时形成从天线元件的平面阵列发射的右手和左旋圆极化信号 。

公开(公告)号：US5489275A

公开(公告)日：1996-02-06

申请号：US338336

申请日：1994-11-14

申请人： Russell B. Thompson ,  David McGee

发明人： Russell B. Thompson ,  David McGee

IPC分类号： A61M25/00 ,  A61M5/00

CPC分类号： A61M25/00 ,  A61M2025/0008 ,  A61M2205/6063

摘要： A catheter assembly which has a distal end adapted for insertion into a living body and a proximal end adapted to remain external to said body or a cable for use in such an assembly includes a cylindrical surface on which are inscribed a plurality of markings. Each of the markings indicates one of the specific locations within the living body at which the distal end may be placed during insertion. The markings are positioned at spaced intervals around the circumference of the cylindrical surface. A sleeve is rotatably and/or axially movable around the cylindrical surface, the sleeve being provided with at least one window adapted to be moved into alignment with a selected one of the markings.

摘要翻译： 具有适于插入生物体的远端和适于保持在所述主体外部的近端或用于这种组件的电缆的导管组件包括其上刻有多个标记的圆柱形表面。 每个标记表示插入期间可以放置远端的活体内的特定位置之一。 标记围绕圆柱形表面的圆周以间隔的间隔定位。 套筒围绕圆柱形表面可旋转和/或轴向移动，套筒设置有至少一个窗口，其适于移动成与选定的一个标记对齐。