公开(公告)号：US08609346B2

公开(公告)日：2013-12-17

申请号：US11920167

申请日：2006-05-11

申请人： Shinobu Kitazume ,  Ritsuko Oka ,  Yasuhiro Hashimoto ,  Tamao Endo ,  Makoto Higuchi ,  Hiroyuki Arai ,  Takaomi Saido ,  Keiko Sato

发明人： Shinobu Kitazume ,  Ritsuko Oka ,  Yasuhiro Hashimoto ,  Yuji Sato ,  Tamao Endo ,  Makoto Higuchi ,  Hiroyuki Arai ,  Takaomi Saido

IPC分类号： G01N33/53 ,  G01N33/96

CPC分类号： G01N33/6896 ,  G01N2800/2821

摘要： It is an object of the present invention to detect a change in the metabolism of a glycoprotein having an α2,6-sialyl residue, which is contained in blood, so as to provide an agent and a method for diagnosing sporadic Alzheimer's disease. The present invention provides an agent for diagnosing Alzheimer's disease, which comprises lectin used for detecting an α2,6-sialyl residue-containing glycoprotein.

摘要翻译： 本发明的目的是检测含有血液中的具有α2,6-唾液酸残基的糖蛋白的代谢变化，从而提供用于诊断散发性阿尔茨海默病的药剂和方法。 本发明提供了用于诊断阿尔茨海默氏病的药剂，其包含用于检测含有α2,6-唾液酸残基的糖蛋白的凝集素。

公开(公告)号：US08574805B2

公开(公告)日：2013-11-05

申请号：US12909398

申请日：2010-10-21

申请人： Yuhei Terui ,  Katsuyuki Nonaka ,  Koji Abe ,  Yasuhiro Hashimoto ,  Naoya Isono ,  Akira Sugiyama

发明人： Yuhei Terui ,  Katsuyuki Nonaka ,  Koji Abe ,  Yasuhiro Hashimoto ,  Naoya Isono ,  Akira Sugiyama

IPC分类号： G03G9/08

CPC分类号： G03G9/08797 ,  G03G9/0806 ,  G03G9/0821 ,  G03G9/08711 ,  G03G9/08782 ,  G03G9/08795

摘要： An object of the present invention is to provide a toner in which the problems in the techniques described are solved. That is, the object is to provide a toner which has an excellent charging characteristic regardless of the environment and which achieves high image quality over a long period of time.A toner includes toner particles including at least a binder resin, a colorant, and a wax, and at least one inorganic fine powder, the toner being characterized in that, in a thermally stimulated current spectrum of the toner measured with a thermally stimulated current measurement apparatus, the thermally stimulated current spectrum of the toner has a specific shape.

摘要翻译： 本发明的目的是提供一种调色剂，其中解决了所述技术中的问题。 也就是说，目的是提供一种具有优异的充电特性的调色剂，而不管环境如何，并且长时间地实现高图像质量。 调色剂包括至少包括粘合剂树脂，着色剂和蜡的调色剂颗粒和至少一种无机细粉，其特征在于，在热刺激电流测量中测量的调色剂的热刺激电流光谱中 装置中，调色剂的热刺激电流光谱具有特定的形状。

公开(公告)号：US20130203184A1

公开(公告)日：2013-08-08

申请号：US13813073

申请日：2011-07-29

申请人： Shinobu Kitazume ,  Naoyuki Taniguchi ,  Yuriko Tachida ,  Takaomi Saido ,  Yasuhiro Hashimoto ,  Takashi Honda

发明人： Shinobu Kitazume ,  Naoyuki Taniguchi ,  Yuriko Tachida ,  Takaomi Saido ,  Yasuhiro Hashimoto ,  Takashi Honda

IPC分类号： G01N33/68

CPC分类号： G01N33/6896 ,  G01N2333/4709 ,  G01N2800/2821

摘要： The present invention provides a method of detecting soluble amyloid β precursor protein 770β derived from vascular endothelial cell, comprising the following steps: (1) a step of contacting a biological sample derived from a test subject suspected of having a disease accompanied by accumulation of amyloid β peptide with an antibody recognizing soluble amyloid β precursor protein β or an amyloid β precursor protein 770-specific antibody; and (2) a step of detecting soluble amyloid β precursor protein 770β in the complex formed in step (1).

摘要翻译： 本发明提供一种检测来自血管内皮细胞的可溶性淀粉样蛋白β前体蛋白770beta的方法，其包括以下步骤：（1）使来自疑似患有伴有淀粉样蛋白积累的疾病的受检对象的生物样品接触的步骤 具有识别可溶性淀粉样蛋白β前体蛋白β或淀粉样蛋白β前体蛋白770特异性抗体的抗体的β肽; 和（2）在步骤（1）中形成的络合物中检测可溶性淀粉样蛋白β前体蛋白770beta的步骤。

公开(公告)号：US08440382B2

公开(公告)日：2013-05-14

申请号：US13153324

申请日：2011-06-03

申请人： Naoya Isono ,  Katsuyuki Nonaka ,  Yasuhiro Hashimoto ,  Akira Sugiyama ,  Yuhei Terui

发明人： Naoya Isono ,  Katsuyuki Nonaka ,  Yasuhiro Hashimoto ,  Akira Sugiyama ,  Yuhei Terui

IPC分类号： G03G9/087

CPC分类号： G03G9/0804 ,  G03G9/0806

摘要： A method of stably producing a toner is provided. This method provides a long-term stabilization of material dispersion in a colorant-dispersed solution and inhibits segregation of the material and provides a more microfine and more uniform dispersion of the colorant in the toner, and moreover produces a toner that has a sharp toner particle diameter distribution. This method of producing toner has at least a colorant dispersion step of obtaining a colorant-dispersed solution by dispersing a pigment-containing colorant in a liquid mixture that contains the colorant and a dissolved resin solution or a polymerizable monomer, wherein the liquid mixture contains a nonionic surfactant and the nonionic surfactant has at least an oxyalkylene group and has a hydrophile-lipophile balance value (HLB value) of 9.0 or more and 17.0 or less.

摘要翻译： 提供了一种稳定地生产调色剂的方法。 该方法提供了在着色剂分散溶液中的材料分散体的长期稳定化，并且抑制了材料的偏析并且提供了更多的微细和更均匀的着色剂在调色剂中的分散体，并且还产生具有尖锐的调色剂颗粒 直径分布。 这种制造调色剂的方法至少具有着色剂分散步骤，其通过将含颜料的着色剂分散在含有着色剂的液体混合物和溶解的树脂溶液或可聚合单体中来获得着色剂分散溶液，其中液体混合物含有 非离子表面活性剂和非离子表面活性剂至少具有氧化烯基，亲水亲油平衡值（HLB值）为9.0以上且17.0以下。

公开(公告)号：US08367289B2

公开(公告)日：2013-02-05

申请号：US12812869

申请日：2009-02-24

申请人： Naoya Isono ,  Satoshi Handa ,  Katsuyuki Nonaka ,  Koji Abe ,  Yasuhiro Hashimoto ,  Akira Sugiyama ,  Yuhei Terui

发明人： Naoya Isono ,  Satoshi Handa ,  Katsuyuki Nonaka ,  Koji Abe ,  Yasuhiro Hashimoto ,  Akira Sugiyama ,  Yuhei Terui

IPC分类号： G03G9/08

CPC分类号： G03G9/09791 ,  G03G9/0806 ,  G03G9/0819 ,  G03G9/0821 ,  G03G9/0827 ,  G03G9/08782

摘要： A toner is provided which is excellent in development stability in both a low-temperature, low-humidity environment and a high-temperature, high-humidity environment over a long time period. The toner includes toner particles containing at least a binder resin and a colorant, and a fatty acid metal salt. The fatty acid metal salt has a volume-based median diameter (D50s) of 0.15 μm or more and 0.65 μm or less, and the liberation ratio of the fatty acid metal salt in the toner is 1.0% or more and 25.0% or less.

摘要翻译： 提供了一种调色剂，其在低温，低湿度环境和高温，高湿度环境下在长时间内具有优异的显影稳定性。 调色剂包括至少含有粘合剂树脂和着色剂的调色剂颗粒和脂肪酸金属盐。 脂肪酸金属盐的体积基准中值粒径（D50s）为0.15μm以上且0.65μm以下，调色剂中的脂肪酸金属盐的释放率为1.0％以上且25.0％以下。

公开(公告)号：US20120315574A1

公开(公告)日：2012-12-13

申请号：US13578813

申请日：2011-05-12

申请人： Katsuyuki Nonaka ,  Yasuhiro Hashimoto ,  Naoya Isono ,  Akira Sugiyama ,  Yuhei Terui

发明人： Katsuyuki Nonaka ,  Yasuhiro Hashimoto ,  Naoya Isono ,  Akira Sugiyama ,  Yuhei Terui

IPC分类号： G03G9/087

CPC分类号： G03G9/09733 ,  G03G9/0806 ,  G03G9/097

摘要： A toner is provided that exhibits a high long-term image stability even during high-speed printing and that also exhibits an excellent environmental stability. The toner comprises a binder resin, a colorant, and a nonionic surfactant, wherein the nonionic surfactant has an oxyethylene group (EO) and an oxypropylene group (PO) and has a ratio of the number of moles of the oxypropylene group to the number of moles of the oxyethylene group (PO/EO) of at least 0.01 and not more than 5.00; and when A (μg/g) is defined as a nonionic surfactant content on the surface of the toner that can be extracted by methanol from 1 g of the toner and B (m2/g) is defined as a theoretical specific surface area determined from a toner particle diameter distribution obtained by a precision particle diameter distribution analyzer that operates based on an aperture electrical resistance method, a ratio A/B is at least 100 μg/m2 and not more than 9000 μg/m2.

摘要翻译： 提供即使在高速印刷期间也表现出高的长期图像稳定性并且也表现出优异的环境稳定性的调色剂。 调色剂包括粘合剂树脂，着色剂和非离子表面活性剂，其中非离子表面活性剂具有氧化乙烯基（EO）和氧化亚丙基（PO），并且氧化丙烯基的摩尔数与 氧乙烯基（PO / EO）的摩尔数为至少0.01且不大于5.00; 并且当将A（μg/ g）定义为可从1g调色剂中由甲醇提取的调色剂表面上的非离子表面活性剂含量，B（m 2 / g）定义为从 通过基于孔径电阻法操作的精密粒径分布分析仪获得的调色剂粒径分布，A / B比至少为100μg/ m 2且不大于9000μg/ m 2。

公开(公告)号：US08053156B2

公开(公告)日：2011-11-08

申请号：US11912650

申请日：2005-11-22

申请人： Koji Abe ,  Satoshi Handa ,  Shinya Yachi ,  Kazumi Yoshizaki ,  Emi Tosaka ,  Yasuhiro Hashimoto ,  Yushi Mikuriya ,  Hitoshi Itabashi

发明人： Koji Abe ,  Satoshi Handa ,  Shinya Yachi ,  Kazumi Yoshizaki ,  Emi Tosaka ,  Yasuhiro Hashimoto ,  Yushi Mikuriya ,  Hitoshi Itabashi

IPC分类号： G03G9/087

CPC分类号： G03G9/0806 ,  G03G9/08795 ,  G03G9/08797

摘要： In a chart of molecular weight distribution measured of a toner, i) the toner has a main peak in the region of molecular weight of 16,000 to 60,000, and ii) where the molecular weight at the main peak is represented by M1, and where the height at the molecular weight M1 is represented by H(M1), the height at a molecular weight of 4,000 by H(4000) and the height at a molecular weight of 15,000 by H(15000), the H(4000), the H(15000) and the H(M1) satisfy a specific proportion. The toner has a weight-average molecular weight (Mw) of 15,000 to 80,000, and, in an endothermic chart, i) the toner has an endothermic main peak in the range of 40 to 130° C., and ii) the calorimetric integral value represented by the peak area of the endothermic main peak is 10 to 35 J per 1 g of the toner.

摘要翻译： 在调色剂测量的分子量分布图中，i）调色剂在分子量为16,000至60,000的区域具有主峰，和ii）主峰分子量由M1表示，其中 分子量M1的高度由H（M1）表示，H（4000）分子量为4000的高度和H（15000）分子量为15,000的高度，H（4000），H （15000）和H（M1）满足特定比例。 调色剂的重均分子量（Mw）为15,000至80,000，并且在吸热图中，i）调色剂具有在40至130℃范围内的吸热主峰，以及ii）量热积分 由吸热主峰的峰面积表示的值为每1g调色剂为10〜35J。

公开(公告)号：US20100178564A1

公开(公告)日：2010-07-15

申请号：US12602934

申请日：2009-03-12

申请人： Takuma Asari ,  Hironori Kumagai ,  Shigeo Hayashi ,  Yasuhiro Hashimoto ,  Takahiro Kawashima

发明人： Takuma Asari ,  Hironori Kumagai ,  Shigeo Hayashi ,  Yasuhiro Hashimoto ,  Takahiro Kawashima

IPC分类号： H01M4/583 ,  B05D5/12 ,  H01G9/155

CPC分类号： H01M4/587 ,  H01G9/016 ,  H01G9/058 ,  H01G11/12 ,  H01G11/26 ,  H01G11/28 ,  H01G11/36 ,  H01G11/86 ,  H01M4/625 ,  H01M4/663 ,  H01M10/052 ,  Y02E60/13 ,  Y02T10/7011 ,  Y02T10/7022

摘要： The present invention provides a highly reliable energy storage device capable of preventing a reaction current from flowing in a carbon nanotube electrode by ionizing a catalyst metal or a substrate metal to cause the metal to flow out to an electrolytic solution. An energy storage device of the present invention includes: at least a pair of electrode bodies that are a cathode and an anode; and an electrolytic solution. At least one of the electrode bodies is configured such that a layer of carbon nanotubes is formed on an electric conductor. A coupling region where one ends of the carbon nanotubes are coupled to and electrically connected to the electric conductor and a non-coupling region where ends of the carbon nanotubes are not coupled to the electric conductor are formed on a surface of the electric conductor. The carbon nanotubes having one ends connected to the coupling region are toppled to cover a surface of the non-coupling region.

摘要翻译： 本发明提供一种高可靠性的能量储存装置，其能够通过使催化剂金属或基板金属离子化而使反应电流流过碳纳米管电极，使金属流出至电解液。 本发明的能量存储装置包括：至少一对电极体，其是阴极和阳极; 和电解液。 至少一个电极体被配置为使得在导电体上形成碳纳米管层。 在电导体的表面上形成有耦合区域，其中碳纳米管的一端耦合到电导体并且电连接到电导体，并且非耦合区域，其中碳纳米管的端部未联接到导电体。 具有连接到耦合区域的一端的碳纳米管被推倒以覆盖非耦合区域的表面。

公开(公告)号：US07637990B2

公开(公告)日：2009-12-29

申请号：US11341439

申请日：2006-01-30

申请人： Hiroshi Tanabe ,  Yasuhiro Hashimoto

发明人： Hiroshi Tanabe ,  Yasuhiro Hashimoto

IPC分类号： B01D19/00

CPC分类号： F16L55/07 ,  Y10T137/3084 ,  Y10T137/3118

摘要： An air vent apparatus for a water tube, comprising: an air separator pipe installed to have an axial direction along a vertical direction, and connected to a portion, where an air reservoir tends to occur, of the water tube for passage of water; and air vent means for venting air accumulating in the air separator pipe.

摘要翻译： 一种用于水管的排气装置，其特征在于，包括：空气分离器管，其安装成具有沿着垂直方向的轴向，并且与所述水管通过的水管容易发生的部分相连接; 以及用于排出积聚在空气分离管中的空气的排气装置。

公开(公告)号：US20090314001A1

公开(公告)日：2009-12-24

申请号：US12442338

申请日：2007-09-19

申请人： Satoshi Tanaka ,  Hiroshi Tanabe ,  Yasuhiro Hashimoto

发明人： Satoshi Tanaka ,  Hiroshi Tanabe ,  Yasuhiro Hashimoto

IPC分类号： F02C1/00

CPC分类号： F02C9/40 ,  F01D19/00 ,  F01D21/00 ,  F02C7/232 ,  F02C7/26

摘要： An object of the present invention is to provide a method of starting and stopping a gas turbine and a start-and-stop control device, which are capable of solving a problem of a failure in normally igniting a fuel gas due to a purge gas (nitrogen gas) remaining in a fuel gas pipe and thereby igniting the fuel gas stably. For this purpose, the start-and-stop control device performs control at the time of starting the gas turbine by sequentially performing: first exhaust gas duct purge for pushing out a fuel gas remaining in an exhaust gas duct with compressed air from a compressor; fuel gas pipe purge for pushing out nitrogen gas remaining in a fuel gas pipe between a fuel gas shutoff valve and a combustor at the time of stopping the gas turbine by the fuel gas by opening a fuel gas shutoff valve; and second exhaust gas duct purge for pushing out the fuel gas remaining in the exhaust gas duct at the time of the fuel gas pipe purge by the compressed air from the compressor, and then the fuel gas is supplied to the combustor by opening the fuel gas shutoff valve again and ignited.

摘要翻译： 本发明的目的是提供一种启动和停止燃气轮机和起动和停止控制装置的方法，其能够解决由于吹扫气体而导致的燃料气体的正常点燃的故障的问题（ 氮气）残留在燃料气体管中，从而稳定地点燃燃料气体。 为此，启动和停止控制装置在启动燃气轮机时，通过依次执行以下步骤来执行控制：第一废气管道吹扫，用于从压缩机推出压缩空气中的残留在废气管道中的燃料气体; 用于通过打开燃料气体截止阀，在燃料气体停止燃气轮机时，在燃料气体切断阀和燃烧器之间排出残留在燃料气体管道中的氮气的燃料气体管道吹扫; 以及第二废气管道吹扫，用于在通过来自压缩机的压缩空气吹扫燃料气体管道时推出残留在排气管道中的燃料气体，然后通过打开燃料气体将燃料气体供应到燃烧器 关闭阀再次点火。