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公开(公告)号：US07368558B2
公开(公告)日：2008-05-06
申请号：US10899671
申请日：2004-07-27
申请人： David Botstein , Audrey Goddard , Paul J. Godowski , Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Margaret Ann Roy , William I. Wood
发明人： David Botstein , Audrey Goddard , Paul J. Godowski , Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Margaret Ann Roy , William I. Wood
CPC分类号： C07K14/47 , C07K14/705
摘要： The present invention is directed to secreted and transmembrane polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译： 本发明涉及分泌和跨膜多肽以及编码这些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号：US07101984B2
公开(公告)日：2006-09-05
申请号：US10033167
申请日：2001-12-27
申请人： David Botstein , Luc Desnoyers , Napoleone Ferrara , Sherman Fong , Wei-Qiang Gao , Audrey Goddard , Austin L. Gurney , James Pan , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , William I. Wood
发明人： David Botstein , Luc Desnoyers , Napoleone Ferrara , Sherman Fong , Wei-Qiang Gao , Audrey Goddard , Austin L. Gurney , James Pan , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , William I. Wood
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20090142800A1
公开(公告)日：2009-06-04
申请号：US11283473
申请日：2005-11-18
申请人： David Botstein , Luc Desnoyers , Napoleone Ferrara , Sherman Fong , Wei-Qiang Gao , Audrey Goddard , Austin L. Gurney , James Pan , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , William I. Wood
发明人： David Botstein , Luc Desnoyers , Napoleone Ferrara , Sherman Fong , Wei-Qiang Gao , Audrey Goddard , Austin L. Gurney , James Pan , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , William I. Wood
IPC分类号： C12P21/02 , C12N15/11 , C12N15/00 , C12N5/06 , C12N9/96 , C07K16/18 , C12N9/02 , C12N1/21 , C12N1/19
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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64.发明授权公开(公告)号：US06929947B2
公开(公告)日：2005-08-16
申请号：US09944944
申请日：2001-08-31
申请人： David Botstein , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Margaret Ann Roy , William I. Wood
发明人： David Botstein , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Margaret Ann Roy , William I. Wood
CPC分类号： C07K14/47 , A61K38/1709
摘要： The present invention is directed to nucleic acids encoding a secreted polypeptide that inhibits neoplastic growth in tumor cells. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译： 本发明涉及编码抑制肿瘤细胞中肿瘤生长的分泌多肽的核酸。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号：US07294695B2
公开(公告)日：2007-11-13
申请号：US10243189
申请日：2002-09-12
申请人： Kevin P. Baker , Dan L. Eaton , Ellen Filvaroff , Audrey Goddard , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean Philippe Stephan , Colin K. Watanabe , William I. Wood , Zemin Zhang , Sherman Fong
发明人： Kevin P. Baker , Dan L. Eaton , Ellen Filvaroff , Audrey Goddard , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean Philippe Stephan , Colin K. Watanabe , William I. Wood , Zemin Zhang , Sherman Fong
IPC分类号： C07K14/00
CPC分类号： C07H21/04 , C07K14/435 , C12N5/06 , C12N9/00 , C12P21/02
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号：US07307153B2
公开(公告)日：2007-12-11
申请号：US10213060
申请日：2002-08-05
申请人： Sherman Fong , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Daniel Tumas , Colin K. Watanabe , William I. Wood , Zemin Zhang
发明人： Sherman Fong , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Daniel Tumas , Colin K. Watanabe , William I. Wood , Zemin Zhang
IPC分类号： C07K16/00 , A61K39/00 , A61K39/395 , A61K39/44 , C12N21/08
CPC分类号： C07K14/47
摘要： The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
摘要翻译： 本发明涉及含有新蛋白质的组合物和使用这些组合物来诊断和治疗免疫相关疾病的方法。
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公开(公告)号：US07452975B2
公开(公告)日：2008-11-18
申请号：US10243167
申请日：2002-09-12
申请人： Kevin P. Baker , Dan L. Eaton , Ellen Filvaroff , Audrey Goddard , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean Philippe Stephan , Colin K. Watanabe , William I. Wood , Zemin Zhang , Sherman Fong
发明人： Kevin P. Baker , Dan L. Eaton , Ellen Filvaroff , Audrey Goddard , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean Philippe Stephan , Colin K. Watanabe , William I. Wood , Zemin Zhang , Sherman Fong
CPC分类号： C07H21/04 , C07K14/435 , C12N5/06 , C12N9/00 , C12P21/02
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号：US07297770B2
公开(公告)日：2007-11-20
申请号：US10243364
申请日：2002-09-12
申请人： Kevin P. Baker , Dan L. Eaton , Ellen Filvaroff , Audrey Goddard , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean Philippe Stephan , Colin K. Watanabe , William I. Wood , Zemin Zhang , Sherman Fong
发明人： Kevin P. Baker , Dan L. Eaton , Ellen Filvaroff , Audrey Goddard , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean Philippe Stephan , Colin K. Watanabe , William I. Wood , Zemin Zhang , Sherman Fong
IPC分类号： C07K14/00
CPC分类号： C07H21/04 , C07K14/435 , C12N5/06 , C12N9/00 , C12P21/02
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods, for producing the polypeptides of the present invention.
摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含这些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明多肽的嵌合多肽分子，与本发明多肽结合的抗体以及用于产生本发明多肽的方法 本发明。
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公开(公告)号：US07294696B2
公开(公告)日：2007-11-13
申请号：US10243345
申请日：2002-09-12
申请人： Kevin P. Baker , Dan L. Eaton , Ellen Filvaroff , Audrey Goddard , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean Philippe Stephan , Colin K. Watanabe , William I. Wood , Zemin Zhang , Sherman Fong
发明人： Kevin P. Baker , Dan L. Eaton , Ellen Filvaroff , Audrey Goddard , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean Philippe Stephan , Colin K. Watanabe , William I. Wood , Zemin Zhang , Sherman Fong
IPC分类号： C07K14/00
CPC分类号： C07H21/04 , C07K14/435 , C12N5/06 , C12N9/00 , C12P21/02
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号：US20080286861A1
公开(公告)日：2008-11-20
申请号：US11945176
申请日：2007-11-26
申请人： Sherman Fong , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Daniel Tumas , Colin K. Watanabe , William I. Wood , Zemin Zhang
发明人： Sherman Fong , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Daniel Tumas , Colin K. Watanabe , William I. Wood , Zemin Zhang
CPC分类号： C07K14/47
摘要： The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
摘要翻译： 本发明涉及含有新蛋白质的组合物和使用这些组合物来诊断和治疗免疫相关疾病的方法。
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