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    Handheld Vacuum Cleaner Tool Comprising a Vacuum Driven Motorized Brush
    62.
    发明申请
    Handheld Vacuum Cleaner Tool Comprising a Vacuum Driven Motorized Brush 审中-公开
    手持式吸尘器工具，包括真空驱动的电动刷

    公开(公告)号：US20130263404A1

    公开(公告)日：2013-10-10

    申请号：US13441051

    申请日：2012-04-06

    申请人： Jason Hill ,  Charles Ostendorf ,  Vincent Lau

    发明人： Jason Hill ,  Charles Ostendorf ,  Vincent Lau

    IPC分类号： A47L5/24 ,  A47L9/04 ,  A47L7/00

    CPC分类号： A47L11/4088 ,  A47L9/0416 ,  A47L9/0483

    摘要： A vacuum cleaner device comprises a main body, a brush device, and a vacuum driven motor. The main body has a primary vacuum inlet, a secondary vacuum inlet, and a vacuum outlet. The secondary vacuum inlet is operatively connected to the vacuum outlet. The brush device is configured and adapted to reciprocate relative to the main body. The vacuum driven motor is adapted and configured to be rotationally driven by air passing through the secondary vacuum inlet to the vacuum outlet. The vacuum driven motor is operatively connected to the brush device in a manner such that rotation of vacuum driven motor causes the brush device to reciprocate relative to the main body.

    摘要翻译： 真空吸尘器装置包括主体，电刷装置和真空驱动电动机。 主体具有初级真空入口，二次真空入口和真空出口。 二次真空入口可操作地连接到真空出口。 刷装置构造并适于相对于主体往复运动。 真空驱动马达被适配和构造成由通过第二真空入口的空气旋转地驱动到真空出口。 真空驱动马达以这样的方式可操作地连接到刷装置，使得真空驱动马达的旋转使刷装置相对于主体往复运动。

    Corkscrew Annuloplasty Device
    63.
    发明申请
    Corkscrew Annuloplasty Device 有权
    开瓶器瓣膜成形术装置

    公开(公告)号：US20120296417A1

    公开(公告)日：2012-11-22

    申请号：US13241603

    申请日：2011-09-23

    申请人： Jason Hill ,  Mark L. Jenson

    发明人： Jason Hill ,  Mark L. Jenson

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2445 ,  A61B17/068 ,  A61B2017/0649 ,  A61F2/2466

    摘要： An annuloplasty device having a plurality of corkscrew anchors is herein disclosed. In some embodiments, the annuloplasty device includes a core wire extending along the length of the device, and at least one corkscrew wire which is operably connected to the corkscrews to screw the corkscrews into heart tissue. In certain embodiments, one or more of the corkscrew wires includes a drive key and the corkscrew anchors are connected to a sleeve with a keyway that engages the drive key on the corkscrew wires. In addition, in some embodiments, the device includes a retractable sheath, which is disposed over the corkscrews to protect them during insertion of the device.

    摘要翻译： 本文公开了一种具有多个开塞钻锚杆的瓣环成形术装置。 在一些实施例中，瓣膜成形术装置包括沿着装置的长度延伸的芯线，以及至少一个可操作地连接到开塞钻头以将开瓶器旋入心脏组织的开塞丝。 在某些实施例中，一个或多个开塞丝包括一个驱动钥匙，并且该开瓶器锚固件通过一个键槽连接到套筒上，键槽与开塞丝线上的驱动钥匙接合。 此外，在一些实施例中，该装置包括可伸缩护套，该可伸缩护套设置在开瓶器上方以在插入装置期间保护它们。

    Broad Spectrum ErbB Ligand Binding Molecules and Methods for Preparing and Using Them
    64.
    发明申请
    Broad Spectrum ErbB Ligand Binding Molecules and Methods for Preparing and Using Them 有权
    广谱ErbB配体结合分子及其制备和使用方法

    公开(公告)号：US20120263707A1

    公开(公告)日：2012-10-18

    申请号：US13359755

    申请日：2012-01-27

    申请人： Jason Hill

    发明人： Jason Hill

    IPC分类号： C07K16/30 ,  A61K39/395 ,  A61P35/00 ,  C12N15/13

    CPC分类号： C12N9/12 ,  A61K38/00 ,  A61K38/177 ,  A61K38/179 ,  C07K14/475 ,  C07K14/705 ,  C07K14/71 ,  C07K2319/30 ,  C07K2319/32 ,  C12Y207/10001

    摘要： Chimeric ErbB ligand binding molecules having detectable binding activity for more ErbB ligands than any one of native ErbB 1, ErbB3 or ErbB4 are disclosed. Preferably, the binding molecules bind a broad spectrum and, more preferably, the full spectrum of ErbB ligands. The chimeric ErbB ligand binding molecules generally have a subunit LI derived from one of ErbB1, 3, or 4 and a subunit LII derived from another distinct ErbB receptor type. The sub-domain, SI, which joins LI and LII can be from either one of the receptor types or can have portions from both. Pharmaceutical compositions that contain the molecules and methods for the treatment of ErbB sensitive diseases are also disclosed.

    摘要翻译： 公开了具有比任何一种天然ErbB1，ErbB3或ErbB4更多ErbB配体具有可检测结合活性的嵌合ErbB配体结合分子。 优选地，结合分子结合广谱，更优选结合全谱的ErbB配体。 嵌合ErbB配体结合分子通常具有衍生自ErbB1,3或4之一的亚单位L1和衍生自另一种不同的ErbB受体型的亚基LII。 连接LI和LII的子结构域SI可以来自受体类型之一，也可以具有来自两者的部分。 还公开了含有分子的药物组合物和用于治疗ErbB敏感性疾病的方法。