Systems and methods employing a bite block insert for positioning and stabilizing external instruments deployed within the body
    62.
    发明申请
    Systems and methods employing a bite block insert for positioning and stabilizing external instruments deployed within the body 审中-公开
    使用咬入块插入件来定位和稳定部署在体内的外部器械的系统和方法

    公开(公告)号:US20080306447A1

    公开(公告)日:2008-12-11

    申请号:US12221850

    申请日:2008-08-07

    Abstract: Systems and methods are provided for positioning and stabilizing an external instrument during insertion of the instrument through the oral cavity (e.g., insertion of a catheter through the oral cavity and into the esophagus or cardia for treatment of gastroesophageal reflux disease (GERD)). The systems and methods provide a gripping tool for association with a bite block, capable of selectively moving between an open position in which the instrument may be inserted or removed, and a closed position in which the external instrument is held in a fixed position.

    Abstract translation: 提供了系统和方法,用于在将器械插入口腔(例如,将导管穿过口腔插入食管或贲门以治疗胃食管反流病(GERD))期间定位和稳定外部器械。 这些系统和方法提供了一种用于与咬合块相关联的夹持工具,其能够选择性地在可以插入或移除该器械的打开位置之间移动,以及将外部器械保持在固定位置的关闭位置。

    Method and apparatus for gastrointestinal tract ablation for treatment of obesity
    65.
    发明授权
    Method and apparatus for gastrointestinal tract ablation for treatment of obesity 有权
    用于治疗肥胖的胃肠道消融的方法和装置

    公开(公告)号:US08641711B2

    公开(公告)日:2014-02-04

    申请号:US12114628

    申请日:2008-05-02

    Abstract: Devices and methods for ablating tissue in the wall of various organs of the gastrointestinal tract of a patient in order to cure or ameliorate metabolic pathophysiological conditions such as obesity, insulin resistance, or type 2 diabetes mellitus are provided. Ablational treatment of target areas may be fractional or partial, rendering a post-treatment portion of target tissue ablated and another portion that is substantially intact. Fractional ablation is achieved by controlling the delivery of ablational energy across the surface area being treated, and controlling the depth of energy penetration into tissue. Surface area control of energy delivery may controlled by the spatial pattern of distributed ablation elements or by the selective activation of a subset of a dense pattern of ablation elements. Embodiments of the device include an ablational electrode array that spans 360 degrees and an array that spans an arc of less than 360 degrees.

    Abstract translation: 提供了用于消除患者胃肠道的各种器官的壁中的组织以便治愈或改善代谢病理生理条件如肥胖,胰岛素抵抗或2型糖尿病的装置和方法。 目标区域的消融治疗可能是部分或部分,使目标组织的后处理部分消融,另一部分基本上完好无损。 通过控制穿过所治疗的表面区域的消融能量的传递并控制能量渗入组织的深度来实现分数消融。 能量输送的表面积控制可以由分布式消融元件的空间模式控制,或者通过选择性地激活消融元件的密集图案的子集。 该装置的实施例包括跨越360度的消融电极阵列和跨越小于360度的弧的阵列。

    Method and apparatus for gastrointestinal tract ablation to achieve loss of persistent and/or recurrent excess body weight following a weight-loss operation
    68.
    发明授权
    Method and apparatus for gastrointestinal tract ablation to achieve loss of persistent and/or recurrent excess body weight following a weight-loss operation 有权
    用于胃肠道消融的方法和装置,以实现减肥手术后持续和/或复发的过量体重的损失

    公开(公告)号:US08251992B2

    公开(公告)日:2012-08-28

    申请号:US12167902

    申请日:2008-07-03

    Abstract: Devices and methods are provided for ablational treatment of regions of the digestive tract in post-bariatric surgery patients who fail to achieve or maintain the desired weight loss. Bariatric procedures include Roux-en-Y gastric bypass, biliopancreatic diversion, and sleeve gastrectomy. These procedures reconstruct gastrointestinal tract features, creating pouches, stoma, and tubes that restrict and/or divert the digestive flow. Post-surgical dilation of altered structures is common and diminishes their bariatric effectiveness. Ablation of compromised structures can reduce their size and compliance, restoring bariatric effectiveness. Ablation, as provided the invention, starts at the mucosa and penetrates deeper into the gastrointestinal wall in a controlled manner. Control may also be provided by a fractional ablation that ablates some tissue within a target region and leaves a portion substantially unaffected. Embodiments of the device include an ablational electrode array that spans 360 degrees and an array that spans an arc of less than 360 degrees.

    Abstract translation: 提供了设备和方法,用于消除不能达到或保持所需体重减轻的减肥手术患者消化道区域的消融。 减肥手术包括Roux-en-Y胃旁路,胆胰管引流和套管胃切除术。 这些程序重建胃肠道特征,产生限制和/或转移消化道的小袋,造口和管。 改变结构的手术后扩张是常见的,并且减轻了他们的减肥效果。 消融受损结构可减少其尺寸和依从性,恢复减肥效果。 根据本发明,消融从粘膜开始并以受控的方式深入胃肠壁。 控制也可以通过消融目标区域内的一些组织并使基本上不受影响的部分的部分消融来提供。 该装置的实施例包括跨越360度的消融电极阵列和跨越小于360度的弧的阵列。

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