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1.发明申请Systems and methods for treating obesity and other gastrointestinal conditions 审中-公开用于治疗肥胖症和其他胃肠病症的系统和方法公开(公告)号：US20090118699A1
公开(公告)日：2009-05-07
申请号：US12317332
申请日：2008-12-22
申请人： David S. Utley , Rachel E. Croft , John W. Gaiser
发明人： David S. Utley , Rachel E. Croft , John W. Gaiser
CPC分类号： A61F5/005 , A61B18/1477 , A61B18/1492 , A61B2017/00818 , A61B2018/00214 , A61B2018/00494 , A61B2018/00553 , A61B2018/1425 , A61B2018/143 , A61B2218/002 , A61F5/0079 , A61F5/0089
摘要： Systems and methods affect tightening of the pyloric sphincter and/or serve to mediate or moderate receptive relaxation of muscles in the stomach, to treat or mitigate various physiologic conditions, such as obesity, biliary reflex, GERD, and/or Barrett's esophagus. The systems and methods may be used as either a primary treatment modality, or applied as a supplementary treatment before, during or after a primary intervention.
摘要翻译： 系统和方法影响幽门括约肌的收缩和/或用于介导或调节胃中肌肉的接受松弛，治疗或减轻各种生理条件，例如肥胖，胆汁反射，GERD和/或巴雷特食管。 系统和方法可以用作主要治疗方式，或者在主要干预之前，期间或之后作为补充治疗使用。
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2.发明申请SYSTEMS AND METHODS FOR TREATING OBESITY AND OTHER GASTROINTESTINAL CONDITIONS 审中-公开用于治疗肥胖和其他胃肠疾病的系统和方法公开(公告)号：US20130072750A1
公开(公告)日：2013-03-21
申请号：US13679785
申请日：2012-11-16
申请人： David S. Utley , Rachel E. Croft , John W. Gaiser
发明人： David S. Utley , Rachel E. Croft , John W. Gaiser
IPC分类号： A61F5/00
CPC分类号： A61F5/005 , A61B18/1477 , A61B18/1492 , A61B2017/00818 , A61B2018/00214 , A61B2018/00494 , A61B2018/00553 , A61B2018/1425 , A61B2018/143 , A61B2218/002 , A61F5/0079 , A61F5/0089
摘要： Systems and methods affect tightening of the pyloric sphincter and/or serve to mediate or moderate receptive relaxation of muscles in the stomach, to treat or mitigate various physiologic conditions, such as obesity, biliary reflex, GERD, and/or Barrett's esophagus. The systems and methods may be used as either a primary treatment modality, or applied as a supplementary treatment before, during or after a primary intervention.
摘要翻译： 系统和方法影响幽门括约肌的收缩和/或用于介导或调节胃中肌肉的接受松弛，治疗或减轻各种生理条件，例如肥胖，胆汁反射，GERD和/或巴雷特食管。 系统和方法可以用作主要治疗方式，或者在主要干预之前，期间或之后作为补充治疗使用。
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3.发明授权Systems and methods for treating obesity and other gastrointestinal conditions 失效用于治疗肥胖症和其他胃肠病症的系统和方法公开(公告)号：US07468060B2
公开(公告)日：2008-12-23
申请号：US10291862
申请日：2002-11-08
申请人： David S. Utley , Rachel E. Croft , John Gaiser
发明人： David S. Utley , Rachel E. Croft , John Gaiser
CPC分类号： A61F5/005 , A61B18/1477 , A61B18/1492 , A61B2017/00818 , A61B2018/00214 , A61B2018/00494 , A61B2018/00553 , A61B2018/1425 , A61B2018/143 , A61B2218/002 , A61F5/0079 , A61F5/0089
摘要： Systems and methods affect tightening of the pyloric sphincter and/or serve to mediate or moderate receptive relaxation of muscles in the stomach, to treat or mitigate various physiologic conditions, such as obesity, biliary reflex, GERD, and/or Barrett's esophagus. The systems and methods may be used as either a primary treatment modality, or applied as a supplementary treatment before, during or after a primary intervention.
摘要翻译： 系统和方法影响幽门括约肌的收缩和/或用于介导或调节胃中肌肉的接受松弛，治疗或减轻各种生理条件，例如肥胖，胆汁反射，GERD和/或巴雷特食管。 系统和方法可以用作主要治疗方式，或者在主要干预之前，期间或之后作为补充治疗使用。
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公开(公告)号：US09107674B2
公开(公告)日：2015-08-18
申请号：US13854662
申请日：2013-04-01
申请人： John W. Gaiser , Scott H. West , David S. Utley , David Huynh
发明人： John W. Gaiser , Scott H. West , David S. Utley , David Huynh
CPC分类号： A61B18/1492 , A61B1/00154 , A61M16/0493 , A61M25/02 , A61M2025/024
摘要： Systems and methods for treating a tissue region employ an expandable structure projecting beyond the distal end of a catheter tube. A distal tail projects beyond the far end of the basket assembly. The distal tail includes a guidewire lumen that accommodates passage of a guidewire without threading the guidewire through the catheter tube.
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公开(公告)号：US20100057080A1
公开(公告)日：2010-03-04
申请号：US12590239
申请日：2009-11-04
申请人： Scott H. West , John W. Gaiser , Robin Bek , David S. Utley , Patrick J. Rimroth
发明人： Scott H. West , John W. Gaiser , Robin Bek , David S. Utley , Patrick J. Rimroth
CPC分类号： A61B18/1492 , A61B1/00087 , A61B1/0014 , A61B1/273 , A61B2018/00029 , A61B2018/00214 , A61B2018/00267 , A61B2018/00797 , A61B2018/00821 , A61B2018/1425 , A61B2018/1475
摘要： Improved devices, systems and methods for treating a tissue region provide straightforward, yet reliable ways for installing diverse functional components within the confined space of a catheter-based instrument.
摘要翻译： 用于治疗组织区域的改进的装置，系统和方法提供了在基于导管的器械的限制空间内安装各种功能组件的简单但可靠的方式。
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6.发明申请公开(公告)号：US20090082721A1
公开(公告)日：2009-03-26
申请号：US12313845
申请日：2008-11-25
申请人： David S. Utley , John W. Gaiser , Rachel Croft
发明人： David S. Utley , John W. Gaiser , Rachel Croft
IPC分类号： A61M5/00
CPC分类号： A61B18/1477 , A61B1/31 , A61B18/12 , A61B18/1206 , A61B18/1485 , A61B18/1492 , A61B2018/00011 , A61B2018/00029 , A61B2018/00077 , A61B2018/00148 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00267 , A61B2018/00273 , A61B2018/00285 , A61B2018/00291 , A61B2018/00482 , A61B2018/00553 , A61B2018/00654 , A61B2018/0066 , A61B2018/00702 , A61B2018/00755 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00875 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/046 , A61B2018/1425 , A61B2018/1475 , A61B2090/3782 , A61B2218/002 , A61B2218/007
摘要： Systems and methods apply a selected treatment agent or agents into contact with tissue at or in the region of a dysfunctional sphincter (in the case of GERD, fecal incontinence, or other dysfunctional sphincter disorders) to affect improved sphincter barrier function and/or to disrupt abnormal nerve pathways. The treatment agent can include at least one cytokine and/or at least one tissue bulking agent and/or at least one vanilloid compound to evoke a desired tissue response. The systems and methods can be used a primary treatment modality, or applied as a supplementary treatment before, during or after a primary intervention.
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公开(公告)号：US06254598B1
公开(公告)日：2001-07-03
申请号：US09235060
申请日：1999-01-20
申请人： Stuart D Edwards , John W. Gaiser , David S. Utley , Jay J. Qin
发明人： Stuart D Edwards , John W. Gaiser , David S. Utley , Jay J. Qin
IPC分类号： A61B1818
CPC分类号： A61B18/1477 , A61B17/32 , A61B18/1206 , A61B18/148 , A61B18/1485 , A61B18/1492 , A61B18/18 , A61B18/1815 , A61B2017/00084 , A61B2017/00106 , A61B2017/003 , A61B2017/22061 , A61B2017/4216 , A61B2018/00011 , A61B2018/00023 , A61B2018/00029 , A61B2018/00065 , A61B2018/00077 , A61B2018/00083 , A61B2018/00113 , A61B2018/00148 , A61B2018/0016 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00494 , A61B2018/00553 , A61B2018/00577 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00726 , A61B2018/00744 , A61B2018/00755 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00821 , A61B2018/00827 , A61B2018/00869 , A61B2018/00875 , A61B2018/00886 , A61B2018/00892 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/00982 , A61B2018/0262 , A61B2018/046 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/1425 , A61B2018/1467 , A61B2018/1472 , A61B2018/183 , A61B2090/3614 , A61B2090/3782 , A61B2218/002 , A61M3/0279 , A61M16/0438 , A61M16/0481 , A61M25/1002 , A61M2025/1052 , A61M2025/1086 , A61N1/056 , A61N1/06 , A61N1/08 , A61N1/40
摘要： A sphincter treatment apparatus includes an elongated member having at least one lumen including an inflation lumen and a basket assembly with first and second arms. The basket assembly is coupled to the elongated member and has deployed and non-deployed configurations. An inflatable member is coupled to the elongated member and positioned in an interior of the basket assembly. The inflatable member has deployed and non-deployed states and is coupled to the inflation lumen. In the deployed state, the inflatable member expands the basket assembly to its deployed configuration. A first energy delivery device is positionable in the first arm and advanceable from the first arm to a selected treatment site. A second energy delivery device is positionable in the second arm and advanceable from the second arm to a selected treatment site.
摘要翻译： 括约肌治疗装置包括细长构件，其具有包括充气腔的至少一个内腔和具有第一和第二臂的篮组件。 筐组件联接到细长构件并且具有展开和非展开构造。 可膨胀构件联接到细长构件并且定位在篮组件的内部。 充气构件具有展开状态和非展开状态，并且连接到膨胀腔。 在展开状态下，可膨胀构件将篮组件膨胀到其展开构型。 第一能量输送装置可定位在第一臂中并且可从第一臂推进到选定的处理部位。 第二能量输送装置可定位在第二臂中并且可从第二臂推进到选定的治疗部位。
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8.发明申请公开(公告)号：US20140221996A1
公开(公告)日：2014-08-07
申请号：US14256979
申请日：2014-04-20
申请人： Scott H. West , John W. Gaiser , Robin Bek , David S. Utley , Patrick Rimroth
发明人： Scott H. West , John W. Gaiser , Robin Bek , David S. Utley , Patrick Rimroth
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B1/00087 , A61B1/0014 , A61B1/273 , A61B2018/00029 , A61B2018/00214 , A61B2018/00267 , A61B2018/00797 , A61B2018/00821 , A61B2018/1425 , A61B2018/1475
摘要： Improved devices, systems and methods for treating a tissue region provide straightforward, yet reliable ways for installing diverse functional components within the confined space of a catheter-based instrument.
摘要翻译： 用于治疗组织区域的改进的装置，系统和方法提供了在基于导管的器械的限制空间内安装各种功能组件的简单但可靠的方式。
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9.发明申请Method to treat gastric reflux via the detection and ablation of gastro-esophageal nerves and receptors 有权通过检测和消融胃食管神经和受体来治疗胃反流的方法公开(公告)号：US20100004648A1
公开(公告)日：2010-01-07
申请号：US12584509
申请日：2009-09-08
CPC分类号： A61B18/1233 , A61B18/1477 , A61B18/1492 , A61B90/39 , A61B2017/00039 , A61B2018/00011 , A61B2018/00029 , A61B2018/00077 , A61B2018/00142 , A61B2018/00148 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00553 , A61B2018/00577 , A61B2018/00654 , A61B2018/00702 , A61B2018/00738 , A61B2018/00791 , A61B2018/00821 , A61B2018/00839 , A61B2018/00875 , A61B2018/00898 , A61B2018/0091 , A61B2018/00982 , A61B2018/0237 , A61B2018/046 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1467 , A61B2090/064 , A61B2090/3782 , A61B2218/002 , A61N1/06
摘要： A method of treating a sphincter provides a sphincter electropotential mapping device with at least one of a mapping electrode or a treatment electrode. The sphincter electropotential mapping device is introduced into at least a portion of the sphincter, the lower esophageal sphincter, stomach, the cardia or the fundus. Bioelectric activity causing a relaxation of the sphincter is detected and energy is delivered from either the mapping electrode or the treatment electrode to treat the bioelectric activity. A method of treating a sphincter provides a sphincter electropotential mapping device with at least one of a mapping electrode or a treatment electrode. The sphincter electropotential mapping device is introduced into at least a portion of the sphincter, the lower esophageal sphincter, stomach, the cardia or the fundus. Bioelectric activity causing a relaxation of the sphincter is detected and energy is delivered from either the mapping electrode or the treatment electrode to treat the bioelectric activity.
摘要翻译： 治疗括约肌的方法提供具有映射电极或治疗电极中的至少一个的括约肌电位映射装置。 括约肌电位映射装置被引入至少一部分括约肌，食管下括约肌，胃，贲门或眼底。 检测到引起松弛括约肌的生物电活性，并从映射电极或治疗电极传递能量以处理生物电活性。 治疗括约肌的方法提供具有映射电极或治疗电极中的至少一个的括约肌电位映射装置。 括约肌电位映射装置被引入至少一部分括约肌，食管下括约肌，胃，贲门或眼底。 检测到引起松弛括约肌的生物电活性，并从映射电极或治疗电极传递能量以处理生物电活性。
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10.发明授权公开(公告)号：US08728074B2
公开(公告)日：2014-05-20
申请号：US12590239
申请日：2009-11-04
申请人： Scott H. West , John W. Gaiser , Robin Bek , David S. Utley , Patrick J. Rimroth
发明人： Scott H. West , John W. Gaiser , Robin Bek , David S. Utley , Patrick J. Rimroth
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B1/00087 , A61B1/0014 , A61B1/273 , A61B2018/00029 , A61B2018/00214 , A61B2018/00267 , A61B2018/00797 , A61B2018/00821 , A61B2018/1425 , A61B2018/1475
摘要： Improved devices, systems and methods for treating a tissue region provide straightforward, yet reliable ways for installing diverse functional components within the confined space of a catheter-based instrument.
摘要翻译： 用于治疗组织区域的改进的装置，系统和方法提供了在基于导管的器械的限制空间内安装各种功能组件的简单但可靠的方式。
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