公开(公告)号：US06530946B1

公开(公告)日：2003-03-11

申请号：US09679399

申请日：2000-10-03

申请人： Wayne Noda ,  Scott Evans ,  Mike Jones

发明人： Wayne Noda ,  Scott Evans ,  Mike Jones

IPC分类号： A61F712

CPC分类号： A61F7/12 ,  A61F7/123 ,  A61F2007/0076 ,  A61F2007/126 ,  A61M25/1011

摘要： A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include at least one balloon which is adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. Embodiments including multiple balloons enhance the surface area of contact, and the mixing of both the heat exchange and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body without cooling the entire body system. It is of particular advantage in brain surgeries where stroke, trauma or cryogenic tumors can best be addressed under hypothermic conditions. Heat pipe technology can be used to form a heat pipe heat exchange catheter. The heat pipe heat exchange catheter includes metallic bellows which allow for flexibility. The temperature control source can be portable to enable the heat pipe heat exchange catheter to be used in the ambulatory environment.

摘要翻译： 导管适于与诸如血管的体导管中流动的体液（例如血液）进行热交换。 导管包括设置在其远端处具有热交换区域的轴。 该区域可以包括至少一个气囊，其适于接收远离冷却的热交换流体，优选地在与体液相反的方向上流动。 包括多个气囊的实施例增强了接触的表面积，以及热交换和体液两者的混合。 导管可以定位成在身体的选择性区域产生低体温，而不会冷却整个身体系统。 在中风，创伤或低温肿瘤可以在低温条件下最好地解决的脑手术中特别有利。 热管技术可用于形成热管换热导管。 热管换热导管包括允许柔性的金属波纹管。 温度控制源可以是便携式的，以使得热管换热导管可以在走动环境中使用。

公开(公告)号：US06409747B1

公开(公告)日：2002-06-25

申请号：US09503014

申请日：2000-02-11

申请人： Yves Pierre Gobin ,  Scott Evans ,  Mike Jones ,  Wayne Noda

发明人： Yves Pierre Gobin ,  Scott Evans ,  Mike Jones ,  Wayne Noda

IPC分类号： A61B1724

CPC分类号： A61F7/12 ,  A61M25/1011

摘要： A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include at least one balloon which is adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. Embodiments including multiple balloons enhance the surface area of contact, and the mixing of both the heat exchange and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body without cooling the entire body system. It is of particular advantage in brain surgeries where stroke, trauma or cryogenic tumors can best be addressed under hypothermic conditions.

公开(公告)号：US06335384B1

公开(公告)日：2002-01-01

申请号：US09680944

申请日：2000-10-10

申请人： Scott Evans ,  John Perl, II ,  Richard Greff

发明人： Scott Evans ,  John Perl, II ,  Richard Greff

IPC分类号： C08L2904

CPC分类号： A61L24/0015 ,  A61L24/001 ,  A61L24/02 ,  A61L24/04 ,  A61L31/02 ,  A61L2300/418 ,  A61L2300/44 ,  A61L2430/36

摘要： Disclosed are methods useful for treating vascular lesions wherein a non-particulate agent such as a metal coil is introduced into a vascular site (e.g., an aneurysm cavity) in conjunction with an embolizing composition comprising a biocompatible polymer and a biocompatible solvent. The biocompatible solvent is miscible or soluble in blood and also solubilizes the polymer during delivery. The biocompatible polymer is selected to be soluble in the biocompatible solvent but insoluble in blood. Upon contact with the blood, the biocompatible solvent dissipates from the embolic composition whereupon the biocompatible polymer precipitates. Precipitation of the polymer in the presence of the non-particular agent permits the agent to act as a structural lattice for the growing polymer precipitate. In another embodiment, the biocompatible polymer composition can be replaced with a biocompatible prepolymer composition containing a biocompatible prepolymer.

摘要翻译： 公开了可用于治疗血管损伤的方法，其中将非颗粒剂如金属盘管与包含生物相容性聚合物和生物相容性溶剂的栓塞组合物一起引入血管部位（例如，动脉瘤腔）。生物相容性溶剂 是可混溶的或可溶于血液，也可以在分娩期间溶解聚合物。 选择生物相容性聚合物可溶于生物相容性溶剂，但不溶于血液。 当与血液接触时，生物相容性溶剂从栓塞组合物中消散，因此生物相容性聚合物沉淀。 聚合物在非特异性试剂存在下的析出允许试剂作为生长聚合物沉淀物的结构晶格。在另一个实施方案中，生物相容性聚合物组合物可以用含有生物相容性预聚物的生物相容性预聚物组合物代替。

公开(公告)号：US06281263B1

公开(公告)日：2001-08-28

申请号：US09438929

申请日：1999-11-12

申请人： Scott Evans ,  John Perl, II ,  Richard Greff

发明人： Scott Evans ,  John Perl, II ,  Richard Greff

IPC分类号： C08L2904

CPC分类号： A61L24/0015 ,  A61L24/001 ,  A61L24/02 ,  A61L24/04 ,  A61L31/02 ,  A61L2300/418 ,  A61L2300/44 ,  A61L2430/36

摘要： Disclosed are methods useful for treating vascular lesions wherein a non-particulate agent such as a metal coil is introduced into a vascular site (e.g., an aneurysm cavity) in conjunction with an embolizing composition comprising a biocompatible polymer and a biocompatible solvent. The biocompatible solvent is miscible or soluble in blood and also solubilizes the polymer during delivery. The biocompatible polymer is selected to be soluble in the biocompatible solvent but insoluble in blood. Upon contact with the blood, the biocompatible solvent dissipates from the embolic composition whereupon the biocompatible polymer precipitates. Precipitation of the polymer in the presence of the non-particulate agent permits the agent to act as a structural lattice for the growing polymer precipitate. In another embodiment, the biocompatible polymer composition can be replaced with a biocompatible prepolymer composition containing a biocompatible prepolymer.

摘要翻译： 公开了可用于治疗血管损伤的方法，其中将非颗粒剂如金属盘管与包含生物相容性聚合物和生物相容性溶剂的栓塞组合物一起引入血管部位（例如，动脉瘤腔）。生物相容性溶剂 是可混溶的或可溶于血液，也可以在分娩期间溶解聚合物。 选择生物相容性聚合物可溶于生物相容性溶剂，但不溶于血液。 当与血液接触时，生物相容性溶剂从栓塞组合物中消散，因此生物相容性聚合物沉淀。 聚合物在非颗粒剂存在下的析出允许试剂作为生长聚合物沉淀物的结构晶格。在另一个实施方案中，生物相容性聚合物组合物可以用含有生物相容性预聚物的生物相容性预聚物组合物代替。

公开(公告)号：US06254588B1

公开(公告)日：2001-07-03

申请号：US09075792

申请日：1998-05-12

申请人： Michael L. Jones ,  Scott Evans ,  George B. Wallace

发明人： Michael L. Jones ,  Scott Evans ,  George B. Wallace

IPC分类号： A61M2500

CPC分类号： A61M25/0012 ,  A61M25/0013 ,  A61M25/0051 ,  A61M25/0053 ,  A61M25/0054 ,  A61M25/007 ,  A61M25/0075 ,  A61M2025/0042

摘要： Disclosed is an elongate flexible microcatheter, for diagnostic and or therapeutic applications. The microcatheter is provided with a small outside diameter and high degree of flexibility, to facilitate negotiation of small, tortuous vessels such as those encountered in intercranial catheterizations. The catheter is formed from a composite of a series of tubular elements, each extending axially for a different distance along the tubular body. A distal section on one or more of the tubular components is provided with a spiral cut, to modify the flexibility properties of the finished catheter. The catheter may also be provided with an inflatable balloon, and a valve to permit the use of a single lumen for both receiving a guidewire and for conveying inflation media.

摘要翻译： 公开了一种细长的柔性微导管，用于诊断和/或治疗应用。 微导管具有较小的外径和高度的灵活性，以便于协商诸如在颅内导管插入术中遇到的小的曲折血管。 导管由一系列管状元件的复合体形成，每个管状元件沿管状体轴向延伸不同的距离。 一个或多个管状部件上的远端部分设置有螺旋切口，以改变成品导管的柔性。 导管还可以设置有可膨胀气囊，以及阀，以允许使用单个内腔来接收导丝并输送充气介质。

公开(公告)号：US6126684A

公开(公告)日：2000-10-03

申请号：US63984

申请日：1998-04-21

申请人： Yves Pierre Gobin ,  Scott Evans ,  Mike Jones ,  Wayne Noda

发明人： Yves Pierre Gobin ,  Scott Evans ,  Mike Jones ,  Wayne Noda

IPC分类号： A61F2/958 ,  A61F7/12

CPC分类号： A61F7/12 ,  A61M25/1011

摘要： A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include at least one balloon which is adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. Embodiments including multiple balloons enhance the surface area of contact, and the mixing of both the heat exchange and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body without cooling the entire body system. It is of particular advantage in brain surgeries where stroke, trauma or cryogenic tumors can best be addressed under hypothermic conditions.

公开(公告)号：US5702361A

公开(公告)日：1997-12-30

申请号：US594574

申请日：1996-01-31

申请人： Scott Evans ,  John Perl, II ,  Richard Greff

发明人： Scott Evans ,  John Perl, II ,  Richard Greff

IPC分类号： A61B17/12 ,  A61K49/04 ,  A61L24/00 ,  A61L24/02 ,  A61L24/04 ,  A61L31/02 ,  A61M1/00

CPC分类号： A61L24/0015 ,  A61L24/001 ,  A61L24/02 ,  A61L24/04 ,  A61L31/02 ,  A61L2300/418 ,  A61L2300/44 ,  A61L2430/36

摘要： Disclosed are methods useful for treating vascular lesions wherein a non-particulate agent such as a metal coil is introduced into a vascular site (e.g., an aneurysm cavity) in conjunction with an embolizing composition comprising a biocompatible polymer and a biocompatible solvent. The biocompatible solvent is miscible or soluble in blood and also solubilizes the polymer during delivery. The biocompatible polymer is selected to be soluble in the biocompatible solvent but insoluble in blood. Upon contact with the blood, the biocompatible solvent dissipates from the embolic composition whereupon the biocompatible polymer precipitates. Precipitation of the polymer in the presence of the non-particulate agent permits the agent to act as a structural lattice for the growing polymer precipitate. In another embodiment, the biocompatible polymer composition can be replaced with a biocompatible prepolymer composition containing a biocompatible prepolymer.

摘要翻译： 公开了可用于治疗血管损伤的方法，其中将非颗粒剂如金属盘管与包含生物相容性聚合物和生物相容性溶剂的栓塞组合物一起引入血管部位（例如，动脉瘤腔）。 生物相容性溶剂是可混溶的或可溶于血液，并且在递送过程中也溶解聚合物。 选择生物相容性聚合物可溶于生物相容性溶剂，但不溶于血液。 当与血液接触时，生物相容性溶剂从栓塞组合物中消散，因此生物相容性聚合物沉淀。 聚合物在非颗粒剂存在下的析出使得该试剂作为生长聚合物沉淀物的结构晶格。 在另一个实施方案中，生物相容性聚合物组合物可以用含有生物相容性预聚物的生物相容性预聚物组合物代替。

公开(公告)号：US5695480A

公开(公告)日：1997-12-09

申请号：US688050

申请日：1996-07-29

申请人： Scott Evans ,  Michael L. Jones ,  Richard Greff

发明人： Scott Evans ,  Michael L. Jones ,  Richard Greff

IPC分类号： A61B17/12 ,  A61K49/00 ,  A61K49/04 ,  A61L24/00 ,  A61L24/04 ,  A61L24/06 ,  A61L24/08 ,  A61M5/00

CPC分类号： A61L24/08 ,  A61B17/12186 ,  A61K49/0419 ,  A61L24/001 ,  A61L24/046 ,  A61L24/06 ,  A61B17/12022 ,  A61L2430/36

摘要： Disclosed are novel compositions for embolizing blood vessels which are particularly suited for treating vascular lesions via catheter delivery. In one embodiment, the compositions of this invention comprise a biocompatible polymer, a biocompatible solvent and a biocompatible water insoluble contrast agent characterized by having an average particle size of less than about 10 .mu.m. In another embodiment, the biocompatible polymer in these compositions is replaced with a biocompatible prepolymer.

摘要翻译： 公开了用于栓塞血管的新型组合物，其特别适用于通过导管递送治疗血管病变。 在一个实施方案中，本发明的组合物包含生物相容性聚合物，生物相容性溶剂和生物相容性水不溶性造影剂，其特征在于平均粒度小于约10μm。 在另一个实施方案中，这些组合物中的生物相容性聚合物被生物相容性预聚物代替。

公开(公告)号：US5263339A

公开(公告)日：1993-11-23

申请号：US923218

申请日：1992-07-31

申请人： Scott Evans

发明人： Scott Evans

IPC分类号： B65D5/46 ,  B65D5/462 ,  B65D5/60 ,  B65D81/38 ,  B31B1/14 ,  B65D5/56

CPC分类号： B65D5/603 ,  B65D5/46112 ,  B65D81/3848 ,  Y10S493/907

摘要： Portable cooler having a base, a lid and four sidewalls, and further having an upper base and an inner sidewall and a liner shaped to fit within the four sidewalls, base and lid. The liner is fixedly attached to the inner sidewall and another sidewall, and is not fixedly attached to any other portion of the cooler.

摘要翻译： 具有底座，盖子和四个侧壁的便携式冷却器，并且还具有上基部和内侧壁以及被成形为装配在四个侧壁，底座和盖子内的衬垫。 衬套固定地附接到内侧壁和另一侧壁，并且不固定地附接到冷却器的任何其它部分。

公开(公告)号：US20180293854A1

公开(公告)日：2018-10-11

申请号：US15480930

申请日：2017-04-06

申请人： Chris Veira ,  Scott Evans ,  Nicole Bagozzi

发明人： Chris Veira ,  Scott Evans ,  Nicole Bagozzi

IPC分类号： G08B7/06 ,  F21S8/04 ,  F21V23/04 ,  F21S9/02 ,  F21V3/02 ,  F21S8/00 ,  G08B5/36

CPC分类号： G08B7/062 ,  F21S8/033 ,  F21S8/043 ,  F21S9/022 ,  F21V3/02 ,  F21V9/08 ,  F21V23/0435 ,  F21Y2103/10 ,  F21Y2115/10 ,  G08B7/066 ,  G08B29/126 ,  G08B29/181 ,  G09F13/00

摘要： A system and method for emergency exit LED lighting. The emergency exit lighting fixture comprises a structure for housing at least one LED light, an LED driver electronically coupled to the LED light(s), a continuous power source, a backup power source, and a test switch. The fixture, in various configurations, may be mounted to a wall, a ceiling, or a doorway. The fixture may be tested remotely.