Fructosylated mangiferin and preparation method therefor and use thereof
    61.
    发明授权
    Fructosylated mangiferin and preparation method therefor and use thereof 有权
    果糖基化芒果苷及其制备方法及其用途

    公开(公告)号:US08946407B2

    公开(公告)日:2015-02-03

    申请号:US14001173

    申请日:2012-03-08

    摘要: Provided are a fructosylated mangiferin, a preparation method therefor and a use thereof, wherein the fructosylated mangiferin has a structural formula represented by the following formula (I), the method for preparing the fructosylated mangiferin includes adding a substance with fructosylating enzymatic activity to a transformed liquid containing mangiferin for biotransformation reaction, so as to convert the mangiferin into the fructosylated mangiferin, wherein the transformed liquid contains the mangiferin and a glycosyl donor; as well as a use of the fructosylated mangiferin in preparation of a medicament for treatment of tumor-related diseases.

    摘要翻译: 提供了一种果糖基化的芒果苷,其制备方法及其用途,其中所述果糖基化的芒果苷具有由下式(I)表示的结构式,所​​述制备所述果糖基化芒果苷的方法包括将具有果糖基酶活性的物质加入转化的 含有芒果苷的液体用于生物转化反应,以将芒果苷转化为果糖基化的芒果苷,其中转化液含有芒果苷和糖供体; 以及在制备用于治疗肿瘤相关疾病的药物中使用果糖基化的芒果苷。

    MULTILEVEL VOLTAGE SOURCE CONVERTERS AND SYSTEMS
    62.
    发明申请
    MULTILEVEL VOLTAGE SOURCE CONVERTERS AND SYSTEMS 有权
    多电压源转换器和系统

    公开(公告)号:US20140376287A1

    公开(公告)日:2014-12-25

    申请号:US13922401

    申请日:2013-06-20

    IPC分类号: H02M3/07

    摘要: Nested neutral point clamped (NNPC) multilevel power converter stages and systems are presented, in which the converter stage includes an NPC inverter core circuit with a flying (switched) capacitor nesting circuit, with the switches of the NPC core and the switched capacitor circuit being gated using selected redundant switching states to control the voltage of the switched capacitors to achieve a multilevel output voltage having equally spaced voltage step values. Multiple inverter stages can meet cascaded or connected in various configurations to implement single or multiphase power conversion systems, and higher output voltages can be achieved by forming to converter stages into an H-bridge configuration, and connecting multiple H-bridge stages in series with one another.

    摘要翻译: 提出了嵌套中性点钳位(NNPC)多电平转换器级和系统,其中转换器级包括具有飞行(开关)电容器嵌套电路的NPC逆变器核心电路,NPC内核和开关电容器电路的开关为 门控使用所选择的冗余切换状态来控制开关电容器的电压以实现具有相等间隔的电压阶跃值的多电平输出电压。 多个逆变器级可以满足级联或连接在各种配置中以实现单相或多相功率转换系统,并且可以通过将转换器级形成H桥配置并且将多个H桥级串联连接到一起来实现更高的输出电压 另一个。

    Method for imaging object using photoneutron transmission and detector arrays using the same
    63.
    发明授权
    Method for imaging object using photoneutron transmission and detector arrays using the same 有权
    使用光子中子传输成像物体的方法及使用其的检测器阵列

    公开(公告)号:US08841627B2

    公开(公告)日:2014-09-23

    申请号:US13519907

    申请日:2010-06-13

    IPC分类号: G01N23/05

    CPC分类号: G01N23/05

    摘要: A method for imaging an object by means of photoneutron transmission is provided. The method determines the position of the photoneutron rays based on the position of a neutron collimator, to overcome the problem of incapability of imaging due to loss of position information of the photoneutrons during moderation thereof. The method also images the object by arranging detector module arrays.

    摘要翻译: 提供了一种通过光子中子传输对物体进行成像的方法。 该方法基于中子准直器的位置来确定光中子射线的位置,以克服由于光调节剂在其适度期间的位置信息的损失而不能成像的问题。 该方法还通过布置检测器模块阵列对对象进行成像。

    Pyrido[3,2-d]pyridazine-2(1H)-one compounds as p38 modulators and methods of use thereof
    66.
    发明授权
    Pyrido[3,2-d]pyridazine-2(1H)-one compounds as p38 modulators and methods of use thereof 失效
    吡啶并[3,2-d]哒嗪-2(1H) - 酮化合物作为p38调节剂及其使用方法

    公开(公告)号:US08420649B2

    公开(公告)日:2013-04-16

    申请号:US13060675

    申请日:2009-08-26

    IPC分类号: A01N43/58 A61K31/50

    CPC分类号: C07D471/04

    摘要: The present invention comprises a new class of compounds useful for the prophylaxis and treatment of protein kinase mediated diseases, including inflammation and related conditions. The compounds have a general Formula I wherein R1, R2, R3, R4, R5, W and X are defined herein. The invention also comprises pharmaceutical compositions including one or more compounds of Formula I, uses of such compounds and compositions for treatment of p38 map kinase mediated diseases including rheumatoid arthritis, psoriasis, chronic obstructive pulmonary disease, pain and other inflammatory disorders, as well as intermediates and processes useful for the preparation of compounds of Formula I.

    摘要翻译: 本发明包括一类新的可用于预防和治疗蛋白激酶介导的疾病,包括炎症和相关病症的化合物。 化合物具有通式I,其中R 1,R 2,R 3,R 4,R 5,W和X如本文所定义。 本发明还包括药物组合物,其包含一种或多种式I化合物,这些化合物和组合物用于治疗p38地图激酶介导的疾病包括类风湿性关节炎,银屑病,慢性阻塞性肺病,疼痛和其它炎性疾病以及中间体 和可用于制备式I化合物的方法。

    Method for Imaging Object Using Photoneutron Transmission and Detector Arrays Using the Same
    67.
    发明申请
    Method for Imaging Object Using Photoneutron Transmission and Detector Arrays Using the Same 有权
    使用光子中子传输和检测器阵列的成像对象的使用方法

    公开(公告)号:US20130026383A1

    公开(公告)日:2013-01-31

    申请号:US13519907

    申请日:2010-06-13

    IPC分类号: G01N23/05

    CPC分类号: G01N23/05

    摘要: A method for imaging an object by means of photoneutron transmission is provided, which comprises the steps of: collimating the photoneutron rays passing through the object by means of a neutron collimator so as to determine the position information of the photoneutron rays based on the position of the neutron collimator; detecting the collimated photoneutron ray beams by means of a detector module, wherein the detector module includes a neutron moderator and at least one thermal neutron detector located within the neutron moderator, wherein the neutron moderator converts the photoneutrons into thermal neutrons, and wherein the thermal neutron detector measures the thermal neutrons so as to obtain attenuation information of the photoneutron ray beams upon passing through the object; and integrating the position information and the attenuation information so as to form an image of the corresponding part of the object. The method determines the position of the photoneutron rays based on the position of a neutron collimator, so as to overcome the problem of incapability of imaging due to loss of position information of the photoneutrons during moderation thereof. The method also images the object by arranging detector module arrays.

    摘要翻译: 提供了一种通过光子中子传输对物体进行成像的方法,其包括以下步骤:通过中子准直器准直通过物体的光中子射线,以便基于位置信息确定光子中子射线的位置信息 中子准直仪; 通过检测器模块检测准直的光子中子射线束,其中检测器模块包括中子减速剂和位于中子慢化剂内的至少一个热中子探测器,其中中子减速剂将光中子转化为热中子,并且其中热中子 检测器测量热中子,以便在通过物体时获得光中子射线束的衰减信息; 并且对位置信息和衰减信息进行积分,以形成对象的对应部分的图像。 该方法基于中子准直器的位置来确定光中子射线的位置,从而克服由于光调节剂在其调节期间的位置信息的损失而不能成像的问题。 该方法还通过布置检测器模块阵列对对象进行成像。

    CIRCUIT FOR CONVERTING DC INTO AC PULSED VOLTAGE
    69.
    发明申请
    CIRCUIT FOR CONVERTING DC INTO AC PULSED VOLTAGE 审中-公开
    将直流转换成交流脉冲电压的电路

    公开(公告)号:US20120104960A1

    公开(公告)日:2012-05-03

    申请号:US13381261

    申请日:2010-06-24

    IPC分类号: H05B41/282 H02M7/537

    CPC分类号: H05B41/2806 Y02B20/22

    摘要: The present invention proposes a circuit for converting DC into AC pulsed voltage. The circuit comprises two or four controllable semiconductor switches as well as a corresponding controller unit. The controller unit controls the opening and closing of the two or four controllable semiconductor switches using a preset control mode. When the circuit is used as the driver circuit of a capacitive load such as a DBD lamp, the luminous efficiency of the DBD lamp is improved.

    摘要翻译: 本发明提出了一种用于将DC转换成AC脉冲电压的电路。 该电路包括两个或四个可控半导体开关以及相应的控制器单元。 控制器单元使用预设控制模式来控制两个或四个可控半导体开关的打开和关闭。 当电路用作诸如DBD灯的电容性负载的驱动电路时,DBD灯的发光效率提高。

    Current source converter-based wind energy system
    70.
    发明授权
    Current source converter-based wind energy system 有权
    基于电流源转换器的风能系统

    公开(公告)号:US08030791B2

    公开(公告)日:2011-10-04

    申请号:US12183816

    申请日:2008-07-31

    IPC分类号: F03D9/00 H02P9/04

    摘要: Power conversion apparatus and methods are presented for providing electrical power to a grid or other load in which a synchronous machine is driven by a wind turbine or other prime mover to provide generator power to a switching type current source converter (CSC), with a current source rectifier (CSR) of the CSC being switched to provide d-axis control of the synchronous machine current based on grid power factor feedback, and with a current source inverter (CSI) of the CSC being switched to provide leading firing angle control and selective employment of dumping resists to dissipate excess generator energy in a fault mode when a grid voltage drops below a predetermined level.

    摘要翻译: 提供了电力转换装置和方法,用于向电网或其他负载提供电力,其中同步电机由风力涡轮机或其它原动机驱动以向开关型电流源转换器(CSC)提供发电机功率,电流 CSC的源极整流器(CSR)被切换以提供基于电网功率因数反馈的同步电机的d轴控制,并且CSC的电流源逆变器(CSI)被切换以提供引导触发角控制和选择性 当电网电压下降到预定水平以下时,使用倾倒抵抗在故障模式下散发过量的发电机能量。