Novel penicillins and their preparation
    65.
    发明授权
    Novel penicillins and their preparation 失效
    新青霉素及其制备

    公开(公告)号:US4003887A

    公开(公告)日:1977-01-18

    申请号:US609982

    申请日:1975-09-03

    IPC分类号: C07D499/00 C07D499/68

    CPC分类号: C07D499/00

    摘要: Novel penicillins of the formula: ##STR1## wherein the ring A is a benzene ring or a 5 or 6-membered heteroaromatic ring containing one or two nitrogen atoms as the hetero atom, on which one or more of lower alkyl, lower alkoxy, lower alkylthio, lower haloalkyl, lower alkylenedioxy halogen, hydroxyl, nitro, free or protected amino, lower alkylamino, di(lower)alkylamino and lower alkanoylamino may be present, Z is a nitrogen atom or a methylene group, X is an oxygen atom or a sulfur atom, Y is a hydrogen atom, a lower alkoxycarbonyl group or a lower alkanoyl group, R.sub.1 is a free or protected hydroxyl group and R.sub.2 and R.sub.3 are each a hydrogen atom or a halogen atom, and their non-toxic pharmaceutically acceptable salts, and their preparation.

    摘要翻译: 新颖的下列青霉素: 其中环A是苯环或含有一个或两个氮原子作为杂原子的5或6元杂芳环,其中一个或多个低级烷基,低级 烷氧基,低级烷硫基,低级卤代烷基,低级亚烷基二氧基卤素,羟基,硝基,游离或被保护的氨基,低级烷基氨基,二(低级)烷基氨基和低级烷酰基氨基,Z是氮原子或亚甲基,X是氧 原子或硫原子,Y为氢原子,低级烷氧基羰基或低级烷酰基,R1为游离或保护的羟基,R2和R3各自为氢原子或卤素原子,其无毒性 可接受的盐及其制备方法。

    Motion vector correction device and method and video signal processing apparatus and method
    67.
    发明授权
    Motion vector correction device and method and video signal processing apparatus and method 有权
    运动矢量校正装置及方法及视频信号处理装置及方法

    公开(公告)号:US09288432B2

    公开(公告)日:2016-03-15

    申请号:US13521390

    申请日:2011-03-09

    IPC分类号: H04N7/01

    CPC分类号: H04N7/014

    摘要: A motion vector detector detects, using pixel data in at least two real frames in an input video signal, a motion vector MV1 necessary for generating interpolated pixel data forming an interpolated frame to be inserted between the two real frames. A motion vector corrector corrects the motion vector MV1 to decrease the magnitude of motion vector MV1 when the magnitude of motion vector MV1 exceeds a predetermined threshold, and outputs it as a motion vector MV3.

    摘要翻译: 运动矢量检测器使用在输入视频信号中的至少两个实际帧中的像素数据来检测形成插入在两个实际帧之间的内插帧的内插像素数据所必需的运动矢量MV1。 当运动矢量MV1的大小超过预定阈值时,运动矢量校正器校正运动矢量MV1以减小运动矢量MV1的大小,并将其作为运动矢量MV3输出。

    MEMBRANE UNIT AND MEMBRANE SEPARATION DEVICE
    68.
    发明申请
    MEMBRANE UNIT AND MEMBRANE SEPARATION DEVICE 有权
    膜单元和膜分离装置

    公开(公告)号:US20130032526A1

    公开(公告)日:2013-02-07

    申请号:US13641944

    申请日:2011-03-25

    IPC分类号: B01D65/02

    摘要: In a membrane separation apparatus, a cleaning effect for membrane elements by scrubbing is improved. In the membrane separation apparatus 14 including a separation membrane 5 (membrane element) dipped in treated liquid in a treatment bath 15, and air diffusing means 2 for diffusing air bubbles 6 for cleaning the separation membrane 5, an air bubbles staying plate 3 is provided between the air diffusing means 2 and the separation membrane 5. The air bubbles staying plate 3 is configured to allow air bubbles 6 diffused from the air diffusing device 2 to stay, by which air bubbles 6 gather each other to form air bubbles 6 having large diameters. By causing air bubbles having large diameters to act on the separation membrane 5, air bubbles 6 can be allowed to act whole the separation membrane 5.

    摘要翻译: 在膜分离装置中,通过洗涤来提高膜元件的清洁效果。 在处理浴15中浸渍处理液的分离膜5(膜元件)的膜分离装置14以及用于扩散用于清洗分离膜5的气泡6的空气扩散装置2设置有气泡滞留板3 空气扩散装置2和分离膜5之间。气泡滞留板3被构造成允许从空气扩散装置2扩散的气泡6停留,由此气泡6彼此聚集以形成具有大的气泡6 直径。 通过使大直径的气泡作用在分离膜5上,可以使气泡6作用于整个分离膜5。

    Factors mutated in the D1 cap region
    70.
    发明授权
    Factors mutated in the D1 cap region 失效
    D1帽区域突变的因素

    公开(公告)号:US5939534A

    公开(公告)日:1999-08-17

    申请号:US669284

    申请日:1996-06-28

    CPC分类号: C07K14/475

    摘要: Human ciliary neurotrophic factor (human CNTF) mutants, in which at least the amino acid residue corresponding to position 153 of wild type human CNTF has been substituted with another amino acid residue in the amino acid sequence encoding human CNTF, exhibit an activity comparable or superior to that of wild type human CNTF. It is therefore expected that the human CNTF mutants would be effective as drugs with improved side effects such as reduction in appearance of an autoantibody, loss of body weight, anorexia, a dry cough, fatigue, etc.In cytokines having sequence similarity to human CNTF and abundant .alpha. helices (GH, PRL, EPO, G- CSF, LIF, IL-6, IL-2, IL-4, GM-CSF), there are further provided mutants in the D1 cap region.

    摘要翻译: PCT No.PCT / JP94 / 02269 Sec。 371日期:1996年6月28日 102(e)日期1996年6月28日PCT 1994年12月27日PCT PCT。 WO95 / 18150 PCT公开号 日期1995年7月6日人类睫状神经营养因子(人CNTF)突变体,其中至少对应于野生型人CNTF的位置153的氨基酸残基已被编码人CNTF的氨基酸序列中的另一个氨基酸残基取代, 与野生型人CNTF相当或优于其活性的活性。 因此,预期人CNTF突变体作为具有改善的副作用的药物是有效的,例如自身抗体的外观减少,体重减轻,厌食,干咳,疲劳等。在与人CNTF具有序列相似性的细胞因子中 和丰富的α螺旋(GH,PRL,EPO,G-CSF,LIF,IL-6,IL-2,IL-4,GM-CSF),还在D1帽区域提供突变体。