公开(公告)号：US20180071537A1

公开(公告)日：2018-03-15

申请号：US15793913

申请日：2017-10-25

Applicant: Valencia Technologies Corporation

Inventor： David K. L. Peterson ,  Jeffrey H. Greiner

IPC: A61N1/378 ,  A61N1/372 ,  A61N1/36

CPC classification number: A61N1/378 ,  A61H39/002 ,  A61H2201/5005 ,  A61H2201/5035 ,  A61H2201/5038 ,  A61H2201/5097 ,  A61N1/36117 ,  A61N1/36125 ,  A61N1/36175 ,  A61N1/37205 ,  A61N1/3756 ,  A61N1/3758 ,  A61N1/3782

Abstract: An implantable electroacupuncture device for treating a medical condition of a patient through application of electroacupuncture stimulation pulses to a target tissue location within the patient includes 1) a housing configured to be implanted beneath a skin surface of the patient, 2) pulse generation circuitry located within the housing and electrically coupled to at least two electrodes, the pulse generation circuitry being adapted to deliver stimulation sessions by way of the at least two electrodes to the target tissue location in accordance with a stimulation regimen, and 3) a primary battery contained within the housing and electrically coupled to the pulse generation circuitry, the primary battery having an internal impedance greater than 5 ohms and a capacity of less than 60 mAh, wherein the primary battery is the only battery that provides power to the pulse generation circuitry.

公开(公告)号：US20180043163A1

公开(公告)日：2018-02-15

申请号：US15793891

申请日：2017-10-25

Applicant: Valencia Technologies Corporation

Inventor： Jeffrey H. Greiner ,  David K. L. Peterson ,  Chuladatta Thenuwara ,  Stacy Greiner Chambliss

IPC: A61N1/36 ,  A61N1/375 ,  A61N1/372 ,  A61N1/05 ,  A61N1/378

CPC classification number: A61N1/36071 ,  A61N1/0551 ,  A61N1/36125 ,  A61N1/36175 ,  A61N1/37205 ,  A61N1/37223 ,  A61N1/3756 ,  A61N1/3758 ,  A61N1/3782 ,  H01L2224/48091 ,  Y10T29/49002 ,  H01L2924/00014

Abstract: An exemplary method treating a chronic low back pain condition in a patient includes 1) generating, by an electroacupuncture device implanted beneath a skin surface of the patient, stimulation sessions at a duty cycle that is less than 0.05, and 2) applying, by the electroacupuncture device in accordance with the duty cycle, the stimulation sessions to a target tissue location within the patient by way of an electrode array located within the patient at an acupoint corresponding to the target tissue location.

公开(公告)号：US09603773B2

公开(公告)日：2017-03-28

申请号：US14805346

申请日：2015-07-21

Applicant: Valencia Technologies Corporation

Inventor： Jeffrey H. Greiner ,  David K. L. Peterson ,  Chuladatta Thenuwara

IPC: A61N1/36 ,  A61H39/00 ,  A61N1/375 ,  A61N1/372 ,  A61N1/378

CPC classification number: A61H39/002 ,  A61H39/00 ,  A61H2201/01 ,  A61N1/3606 ,  A61N1/36114 ,  A61N1/36117 ,  A61N1/36125 ,  A61N1/36153 ,  A61N1/36157 ,  A61N1/36175 ,  A61N1/37205 ,  A61N1/37223 ,  A61N1/3756 ,  A61N1/3782 ,  A61N1/3787 ,  Y10T29/49002

Abstract: An exemplary method treating a cardiovascular disease in a patient includes 1) generating, by an electroacupuncture device implanted beneath a skin surface of the patient at an acupoint corresponding to a median nerve of the patient, stimulation sessions at a duty cycle that is less than 0.05, wherein the duty cycle is a ratio of T3 to T4, each stimulation session included in the stimulation sessions has a duration of T3 minutes and occurs at a rate of once every T4 minutes, and the electroacupuncture device comprises a central electrode of a first polarity and an annular electrode of a second polarity and that is spaced apart from the central electrode; and 2) applying, by the electroacupuncture device, the stimulation sessions to the median nerve by way of the central electrode and the annular electrode in accordance with the duty cycle.

公开(公告)号：US09566212B2

公开(公告)日：2017-02-14

申请号：US14859088

申请日：2015-09-18

Applicant: Valencia Technologies Corporation

Inventor： Jeffrey H. Greiner ,  David K. L. Peterson ,  Chuladatta Thenuwara ,  Stacy Greiner Chambliss

IPC: A61N1/375 ,  A61H39/00 ,  A61N1/36 ,  A61N1/372 ,  A61F5/00 ,  A61N1/378

CPC classification number: A61H39/002 ,  A61F5/0026 ,  A61H2201/50 ,  A61H2201/5005 ,  A61H2201/5038 ,  A61H2201/5097 ,  A61N1/36085 ,  A61N1/36117 ,  A61N1/36125 ,  A61N1/36153 ,  A61N1/36157 ,  A61N1/36175 ,  A61N1/37205 ,  A61N1/375 ,  A61N1/3756 ,  A61N1/3758 ,  A61N1/3782 ,  Y10T29/49117

Abstract: An exemplary method of treating obesity or dyslipidemia of a patient using a small implantable electroacupuncture device (IEAD) includes 1) implanting the IEAD below the skin surface of the patient at or near a target tissue location selected from the group of target tissue locations comprising acupoints ST36, SP4, ST37, ST40, SP6, SP9, K16, LR8 and their underlying nerves, the saphenous nerve and the peroneal nerve, and 2) enabling the IEAD to provide EA stimulation pulses in accordance with a stimulation regimen that provides a stimulation session having a duration of T3 minutes at a rate of once every T4 minutes, where the ratio of T3/T4 is no greater than 0.05, and wherein T3 is at least 10 minutes and no greater than 60 minutes.

Abstract translation: 使用小型可植入电针装置（IEAD）治疗患者的肥胖症或血脂异常的示例性方法包括：1）在选自包括穴位的目标组织位置组中的目标组织位置处或附近将患者的皮肤表面植入患者的皮肤表面 ST36，SP4，ST37，ST40，SP6，SP9，K16，LR8及其潜在的神经，隐神经和腓神经，以及2）使IEAD能够根据提供刺激疗程的刺激方案提供EA刺激脉冲 以T3 / T4比不大于0.05的速度每T4分钟一次持续T3分钟，其中T3至少为10分钟且不大于60分钟。

公开(公告)号：US20150328460A1

公开(公告)日：2015-11-19

申请号：US14811633

申请日：2015-07-28

Applicant: Valencia Technologies Corporation

Inventor： Jeffrey H. Greiner ,  David K. L. Peterson ,  Chuladatta Thenuwara ,  Stacy Greiner Chambliss

IPC: A61N1/36 ,  A61N1/372 ,  A61N1/375 ,  A61N1/05

CPC classification number: A61N1/36071 ,  A61N1/0551 ,  A61N1/36125 ,  A61N1/36175 ,  A61N1/37205 ,  A61N1/37223 ,  A61N1/3756 ,  A61N1/3758 ,  A61N1/3782 ,  H01L2224/48091 ,  Y10T29/49002 ,  H01L2924/00014

Abstract: An exemplary method of treating a chronic low back pain condition in a patient includes 1) generating, by an electroacupuncture device implanted beneath a skin surface of the patient at at least one of acupoints BL22, BL23, BL24, BL25, and BL26 within the patient, stimulation sessions at a duty cycle that is less than 0.05, wherein the duty cycle is a ratio of T3 to T4 and each stimulation session included in the stimulation sessions has a duration of T3 minutes and occurs at a rate of once every T4 minutes, and 2) applying, by the electroacupuncture device, the stimulation sessions to the target tissue location in accordance with the duty cycle.

Abstract translation: 一种治疗患者慢性腰痛症状的示例性方法包括：通过在患者体内植入患者皮肤表面下方的电针BL22，BL23，BL24，BL25和BL26中的至少一个产生电刺激装置 ，小于0.05的占空比的刺激会话，其中占空比是T3到T4的比例，并且包括在刺激会话中的每个刺激会话具有T3分钟的持续时间并以每T4分钟一次的速率发生， 和2）根据占空比通过电针装置将刺激会话应用于目标组织位置。

公开(公告)号：US20150313750A1

公开(公告)日：2015-11-05

申请号：US14799492

申请日：2015-07-14

Applicant: Valencia Technologies Corporation

Inventor： Jeffrey H. Greiner ,  David K. L. Peterson ,  Chuladatta Thenuwara ,  Stacy O. Greiner

IPC: A61F5/41 ,  A61N1/36

CPC classification number: A61F5/41 ,  A61F2005/418 ,  A61H39/002 ,  A61H2201/5005 ,  A61H2201/5038 ,  A61H2201/5097 ,  A61H2205/087 ,  A61N1/18 ,  A61N1/36107 ,  A61N1/36125 ,  A61N1/36153 ,  A61N1/36157 ,  A61N1/36175 ,  A61N1/362 ,  A61N1/37205 ,  A61N1/375 ,  A61N1/3756 ,  A61N1/3758 ,  A61N1/3782 ,  Y10T29/49002

Abstract: An implantable electroacupuncture device (IEAD) treats an erectile dysfunction condition of a patient through application of stimulation pulses applied at a target tissue location underlying, or in the vicinity of, at least one of acupoints BL52, BL23 or GV4. The IEAD includes an IEAD housing having an electrode configuration thereon that includes at least two electrodes, and pulse generation circuitry located within the IEAD housing and electrically coupled to the at least two electrodes. The pulse generation circuitry is adapted to deliver EA stimulation pulses to the patient's body tissue at or near the target tissue location in accordance with a specified stimulation regimen, the stimulation regimen requiring that the stimulation session have a duration of T3 minutes and a rate of occurrence of once every T4 minutes, and wherein a ratio of T3/T4 is no greater than 0.05.

Abstract translation: 可植入电针装置（IEAD）通过施加施加在穴位BL52，BL23或GV4中的至少一个穴位下方或附近的目标组织位置处的刺激脉冲来治疗患者的勃起功能障碍状况。 IEAD包括其上具有电极配置的IEAD外壳，其包括至少两个电极，以及位于IEAD外壳内并电耦合到至少两个电极的脉冲发生电路。 脉冲发生电路适于根据指定的刺激方案将EA刺激脉冲输送到目标组织位置处或附近的患者身体组织，刺激方案要求刺激疗程具有T3分钟的持续时间和出现发生率 每T4分钟一次，其中T3 / T4的比例不大于0.05。

公开(公告)号：US20150231030A1

公开(公告)日：2015-08-20

申请号：US14669145

申请日：2015-03-26

Applicant: Valencia Technologies Corporation

Inventor： Jeffrey H. Greiner ,  David K. L. Peterson ,  Chuladatta Thenuwara

IPC: A61H39/00 ,  A61N1/36

CPC classification number: A61H39/002 ,  A61H39/00 ,  A61H2201/01 ,  A61N1/3606 ,  A61N1/36114 ,  A61N1/36117 ,  A61N1/36125 ,  A61N1/36153 ,  A61N1/36157 ,  A61N1/36175 ,  A61N1/37205 ,  A61N1/37223 ,  A61N1/3756 ,  A61N1/3782 ,  A61N1/3787 ,  Y10T29/49002

Abstract: An Implantable ElectroAcupuncture Device (IEAD) treats cardiovascular disease through application of stimulation pulses applied at at least one of acupoints EX-HN1, BL14, HT7, HT5, PC6, ST36, LI11, LU7, and LU2. The IEAD comprises an implantable, coin-sized, self-contained, leadless electroacupuncture device having at least two electrodes attached to an outside surface of its housing. The device generates stimulation pulses in accordance with a specified stimulation regimen. Power management circuitry within the device allows a primary battery, having a high internal impedance, to be used to power the device. The stimulation regimen generates stimulation pulses during a stimulation session of duration T3 minutes applied every T4 minutes. The duty cycle, or ratio T3/T4 is very low, no greater than 0.05. The low duty cycle and careful power management allow the IEAD to perform its intended function for several years.

Abstract translation: 可植入电针装置（IEAD）通过施加在穴位EX-HN1，BL14，HT7，HT5，PC6，ST36，LI11，LU7和LU2中的至少一个上施加的刺激脉冲来治疗心血管疾病。 IEAD包括可植入的硬币尺寸的独立的无引线电针装置，其具有附接到其外壳的外表面的至少两个电极。 该设备根据指定的刺激方案产生刺激脉冲。 设备内的电源管理电路允许使用具有高内部阻抗的一次电池为设备供电。 刺激方案在每T4分钟施用持续时间T3分钟的刺激期间产生刺激脉冲。 占空比或比例T3 / T4非常低，不大于0.05。 低占空比和仔细的电源管理允许IEAD执行其预期功能几年。

公开(公告)号：US09089716B2

公开(公告)日：2015-07-28

申请号：US13769699

申请日：2013-02-18

Applicant: Valencia Technologies Corporation

Inventor： David K. L. Peterson ,  Jeffrey H. Greiner

IPC: A61N1/378 ,  A61N1/375 ,  A61H39/00 ,  A61N1/372 ,  A61N1/36

CPC classification number: A61N1/378 ,  A61H39/002 ,  A61H2201/5005 ,  A61H2201/5035 ,  A61H2201/5038 ,  A61H2201/5097 ,  A61N1/36117 ,  A61N1/36125 ,  A61N1/36175 ,  A61N1/37205 ,  A61N1/3756 ,  A61N1/3758 ,  A61N1/3782

Abstract: An implantable electroacupuncture device (IEAD) treats a disease or medical condition of a patient through application of stimulation pulses applied at a specified acupoint or other target tissue location. In a preferred implementation, the IEAD is an implantable, coin-sized, self-contained, leadless electroacupuncture device having at least two electrodes attached to an outside surface of its housing. The device generates stimulation pulses in accordance with a specified stimulation regimen. Power management circuitry within the device allows a primary battery, having a high internal impedance, to be used to power the device. The stimulation regimen generates stimulation pulses during a stimulation session of duration T3 minutes applied every T4 minutes. The duty cycle, or ratio T3/T4, is very low, no greater than 0.05. The low duty cycle and careful power management allow the IEAD to perform its intended function for several years.

Abstract translation: 可植入电针装置（IEAD）通过施加在特定穴位或其他目标组织位置施加的刺激脉冲来治疗患者的疾病或医学状况。 在优选的实施方案中，IEAD是可植入的硬币大小的独立的无引线电针装置，其具有附接到其外壳的外表面的至少两个电极。 该设备根据指定的刺激方案产生刺激脉冲。 设备内的电源管理电路允许使用具有高内部阻抗的一次电池为设备供电。 刺激方案在每T4分钟施用持续时间T3分钟的刺激期间产生刺激脉冲。 占空比或比例T3 / T4非常低，不大于0.05。 低占空比和仔细的电源管理允许IEAD执行其预期功能几年。

公开(公告)号：US08942816B2

公开(公告)日：2015-01-27

申请号：US13736041

申请日：2013-01-07

Applicant: Valencia Technologies Corporation

Inventor： Jeffrey H. Greiner ,  David K. L. Peterson ,  Chuladatta Thenuwara ,  Stacy O. Greiner

IPC: A61N1/05 ,  A61H39/00

CPC classification number: A61H39/002 ,  A61H2201/5035 ,  A61H2201/5038 ,  A61H2201/5097 ,  A61N1/3606 ,  A61N1/36085 ,  A61N1/36125 ,  A61N1/36153 ,  A61N1/36157 ,  A61N1/36175 ,  A61N1/37205 ,  A61N1/3756 ,  A61N1/3758 ,  A61N1/3782 ,  Y10T29/49117

Abstract: An Implantable ElectroAcupuncture Device (IEAD) treats dyslipidemia conditions of a patient through application of stimulation pulses applied at acupoint ST40, or its underlying nerves saphenous and peroneal. The IEAD comprises an implantable, coin-sized, self-contained, leadless electroacupuncture device having at least two electrodes attached to an outside surface of its housing. The device generates stimulation pulses in accordance with a specified stimulation regimen. Power management circuitry within the device allows a primary battery, having a high internal impedance, to be used to power the device. The stimulation regimen generates stimulation pulses during a stimulation session of duration T3 minutes applied every T4 minutes. The duty cycle, or ratio T3/T4, is very low, no greater than 0.05. The low duty cycle and careful power management allow the IEAD to perform its intended function for several years.

Abstract translation: 可植入电针装置（IEAD）通过施加在穴位ST40施加的刺激脉冲或其潜伏的隐神经和腓神经来治疗患者的血脂异常状况。 IEAD包括可植入的硬币大小的独立的无引线电针装置，其具有附接到其外壳的外表面的至少两个电极。 该设备根据指定的刺激方案产生刺激脉冲。 设备内的电源管理电路允许使用具有高内部阻抗的一次电池为设备供电。 刺激方案在每T4分钟施用持续时间T3分钟的刺激期间产生刺激脉冲。 占空比或比例T3 / T4非常低，不大于0.05。 低占空比和仔细的电源管理允许IEAD执行其预期功能几年。

公开(公告)号：US20140214126A1

公开(公告)日：2014-07-31

申请号：US13736039

申请日：2013-01-07

Applicant: Valencia Technologies Corporation

Inventor： Jeffrey H. Greiner ,  David K. L. Peterson ,  Chuladatta Thenuwara ,  Stacy O. Greiner

IPC: A61H39/00

CPC classification number: A61H39/002 ,  A61H2201/01 ,  A61H2201/5005 ,  A61H2201/5038 ,  A61N1/32 ,  A61N1/36085 ,  A61N1/36089 ,  A61N1/36125 ,  A61N1/36153 ,  A61N1/36157 ,  A61N1/36175 ,  A61N1/37205 ,  A61N1/3756 ,  A61N1/3758 ,  A61N1/3782 ,  Y10T29/49208

Abstract: An implantable electroacupuncture device (IEAD) treats obese conditions of a patient through application of stimulation pulses applied at acupoints SP4, LR8 or ST40, or their underlying nerves saphenous and peroneal. The IEAD comprises an implantable, coin-sized, self-contained, leadless electroacupuncture device having at least two electrodes attached to an outside surface of its housing. The device generates stimulation pulses in accordance with a specified stimulation regimen. Power management circuitry within the device allows a primary battery, having a high internal impedance, to be used to power the device. The stimulation regimen generates stimulation pulses during a stimulation session of duration T3 minutes applied every T4 minutes. The duty cycle, or ratio T3/T4, is very low, no greater than 0.05. The low duty cycle and careful power management allow the IEAD to perform its intended function for several years.

Abstract translation: 可植入电针装置（IEAD）通过施加在穴位SP4，LR8或ST40上施加的刺激脉冲或其潜伏的隐神经和腓神经来治疗患者的肥胖状况。 IEAD包括可植入的硬币大小的独立的无引线电针装置，其具有附接到其外壳的外表面的至少两个电极。 该设备根据指定的刺激方案产生刺激脉冲。 设备内的电源管理电路允许使用具有高内部阻抗的一次电池为设备供电。 刺激方案在每T4分钟施用持续时间T3分钟的刺激期间产生刺激脉冲。 占空比或比例T3 / T4非常低，不大于0.05。 低占空比和仔细的电源管理允许IEAD执行其预期功能几年。