公开(公告)号：US07313395B2

公开(公告)日：2007-12-25

申请号：US10815834

申请日：2004-04-02

申请人： Young Jo Lee

发明人： Young Jo Lee

IPC分类号： H04Q7/20 ,  H04B7/00

CPC分类号： H04L1/0018 ,  H04L1/0002 ,  H04L1/0025

摘要： A wireless communication terminal adaptively controls a forward data rate based on a channel status and with regard to a delay time existing between the detecting of the channel status and transmitting the data. An adaptive data rate control (DRC) method includes steps of receiving a pilot signal from a base station; detecting a channel status by measuring a power level of the received pilot signal; calculating a delay time, the delay time equaling a time interval indicative a pilot signal and reception of a data signal; determining a target forward data rate based on an offset value corresponding to the delay time; and transmitting a value indicative of the target forward data rate to the base station. The forward data rate is requested in consideration of the delay time.

摘要翻译： 无线通信终端基于信道状态以及存在于信道状态的检测和发送数据之间的延迟时间自适应地控制前向数据速率。 自适应数据速率控制（DRC）方法包括从基站接收导频信号的步骤; 通过测量接收到的导频信号的功率电平来检测信道状态; 计算延迟时间，延迟时间等于指示导频信号的时间间隔和数据信号的接收; 基于与延迟时间对应的偏移值来确定目标前向数据速率; 以及向所述基站发送指示所述目标前向数据速率的值。 考虑到延迟时间请求转发数据速率。

公开(公告)号：US06574204B1

公开(公告)日：2003-06-03

申请号：US09273765

申请日：1999-03-22

申请人： Young Jo Lee

发明人： Young Jo Lee

IPC分类号： H04B7216

CPC分类号： H04B1/71072 ,  H04B2201/70703

摘要： A method of canceling interference components included in received signals of a base station in a mobile communication system, despreads user data in the order of user data grouped for the unit of transmission rate and sequentially cancels user data which are the same as despread user data by allowing the base station to know transmission rate and user codes of user data transmitted from respective terminals, in case that the respective terminals transmit various user data which require various transmission rates in the mobile communication system of CDMA type. The method includes the steps of correlating user data in parallel using high transmission rate of data and user codes of respective terminals by receiving the user data transmitted from the respective terminals in the base station, the transmission rate of data and user codes of the respective terminals being in advance known by the base station, comparing the correlated resultant values with one another to decode one correlation value having one maximum value, and spreading the one correlation value having the maximum value using the user codes and subtracting user data obtained during spreading step from input user data.

摘要翻译： 一种消除移动通信系统中的基站的接收信号中包含的干扰成分的方法，按照传输速率单位分组的用户数据顺序对用户数据进行解扩，并依次取消与解扩用户数据相同的用户数据， 允许基站在CDMA类型的移动通信系统中各个终端发送需要各种传输速率的各种用户数据的情况下，知道从各个终端发送的用户数据的传输速率和用户代码。 该方法包括以下步骤：通过接收从基站中的各个终端发送的用户数据，相应终端的数据传输速率和用户代码，使用数据的高传输速率和各个终端的用户代码来并行地将用户数据相关联 由基站预先知道，将相关的结果值彼此进行比较，以解码具有一个最大值的一个相关值，并且使用用户代码扩展具有最大值的一个相关值，并且从扩展步骤中获得的用户数据减去 输入用户数据。

公开(公告)号：US06507744B1

公开(公告)日：2003-01-14

申请号：US09468605

申请日：1999-12-21

申请人： Jong Sun Han ,  Young Jo Lee

发明人： Jong Sun Han ,  Young Jo Lee

IPC分类号： H04Q720

CPC分类号： H04W52/12 ,  H04W36/18 ,  H04W52/20 ,  H04W52/36 ,  H04W52/40

摘要： An outer loop power control method for a mobile communication system is disclosed. By implementing two outer loop power control methods, one for a normal mode and the other for a soft handoff mode, the outer loop power control in the present invention variably adjusts the ratio of up/down step size for a power control threshold value during a soft handoff operation.

摘要翻译： 公开了一种移动通信系统的外环功率控制方法。 通过实现两个外部环路功率控制方法，一个用于正常模式，另一个用于软切换模式，本发明中的外部环路功率控制可变地调节在一个功率控制阈值期间的上升/下降步长的比率 软切换操作。

公开(公告)号：US10752938B2

公开(公告)日：2020-08-25

申请号：US15124700

申请日：2014-06-17

申请人： SEEGENE, INC. ,  Jong Yoon Chun ,  Young Jo Lee

发明人： Jong Yoon Chun ,  Young Jo Lee

IPC分类号： C12Q1/68 ,  G01N25/04 ,  C12Q1/6816 ,  C12Q1/6827 ,  C12Q1/6858

摘要： The present invention relates to detection of a target nucleic acid sequence in a sample using two different detection temperatures. The present invention using difference between signals detected at two detection temperatures enables to decrease well-to-well variation or sample-to-sample variation generated in real-time PCR processes in more convenient and effective manner.

公开(公告)号：US09328377B2

公开(公告)日：2016-05-03

申请号：US13508086

申请日：2009-11-28

申请人： Jong Yoon Chun ,  In Taek Hwang ,  Young Jo Lee

发明人： Jong Yoon Chun ,  In Taek Hwang ,  Young Jo Lee

IPC分类号： C12P19/34 ,  C12Q1/68

CPC分类号： C12Q1/6823 ,  C12Q1/6818 ,  C12Q1/6851 ,  C12Q1/6853 ,  C12Q2565/1015 ,  C12Q2561/113 ,  C12Q2561/101

摘要： The present invention relates to the detection of a target nucleic acid sequence using a target hybridization and detection primer (THD primer). The present invention allows for both a target amplification and a signal amplification by introducing a label into a primer used in PCR reactions, ensuring a real-time target detection by PCR reaction by no use of complicated oligonucleotides. The present invention could completely be free from the troublesome matters and shortcomings associated with conventional real-time PCR methods. The present invention allows for successful real-time target detection by using only a labeled primer. This feature makes it possible that the present invention exhibits excellent real-time target detection in multiplex manner.

摘要翻译： 本发明涉及使用靶杂交和检测引物（THD引物）检测靶核酸序列。 本发明通过在PCR反应中使用的引物中引入标记物来允许目标扩增和信号扩增两者，通过不使用复杂的寡核苷酸来确保PCR反应的实时目标检测。 本发明可以完全免除与常规实时PCR方法相关的麻烦的问题和缺点。 本发明允许仅使用标记的引物成功实现目标检测。 该特征使得本发明可以以多路复用方式显示出优异的实时目标检测。

公开(公告)号：US20140073534A1

公开(公告)日：2014-03-13

申请号：US14114253

申请日：2012-05-03

申请人： Jong Yoon Chun ,  Young Jo Lee

发明人： Jong Yoon Chun ,  Young Jo Lee

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6823 ,  C12Q2521/319 ,  C12Q2565/519

摘要： The present invention relates to the detection of a target nucleic acid sequence by a POCH (PO Cleavage and Hybridization) assay on a solid substrate. The present invention detects the target nucleic acid sequence by use of in which the PO (Probing Oligonucleotide) hybridized with the target nucleic acid sequence is cleaved and the cleavage of the PO is detected by hybridization with the CO (Capturing Oligonucleotide). In the present invention, an uncleaved PO is hybridized with the CO immobilized onto the solid substrate. The designs of the PO and the CO are convenient and the optimization of reaction conditions is routinely easy in the present invention. Where the detection of signal on the solid substrate is continuously performed along with repetition of cleavage of the POs in the present invention, the number of the POs cleaved is increased upon the repetition number of the cleavage reaction and the signal is changed in parallel with the number of the POs cleaved. Then, the target nucleic acid sequence can be detected in a real-time manner. In contrast, the change of the signal is not observed in the absence of the target nucleic acid sequence.

摘要翻译： 本发明涉及通过在固体基质上的POCH（PO切割和杂交）测定法检测靶核酸序列。 本发明通过使用其中与靶核酸序列杂交的PO（探针寡核苷酸）被切割并通过与CO（捕获寡核苷酸）杂交来检测PO的切割来检测靶核酸序列。 在本发明中，未切割的PO与固定在固体基质上的CO杂交。 PO和CO的设计是方便的，并且在本发明中反应条件的优化通常很容易。 在本发明中连续进行PO的切割的情况下连续进行固体基板上的信号检测的情况下，切割反应的次数随着切割反应的重复次数而增加，信号与 PO的数量劈开。 然后，可以以实时的方式检测靶核酸序列。 相比之下，在没有靶核酸序列的情况下，没有观察到信号的变化。

公开(公告)号：US20130190208A1

公开(公告)日：2013-07-25

申请号：US13824688

申请日：2010-12-23

申请人： Jong Yoon Chun ,  Young Jo Lee

发明人： Jong Yoon Chun ,  Young Jo Lee

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6834 ,  C12Q1/6816 ,  C12Q1/6823 ,  C12Q1/6876 ,  C12Q2521/319 ,  C12Q2563/107 ,  C12Q2565/30 ,  C12Q2565/519

摘要： The present invention relates to a novel method for detection of target nucleic acid sequences by cyclic exonucleolytic reactions (CER) or exonucleolytic reactions (ER) using single-labeled immobilized probes on a solid phase. The present invention enables to detect target nucleic acid sequences on a solid phase using single-labeled systems. Comparing with multiple-labeled systems such as dual labeling, the present invention using single-labeled probes has excellent advantages in light of convenience and cost effectiveness in probe design and preparation. Furthermore, the measurement of changes of the signal decrease during reactions is responsible for more accurate qualitative and quantitative analysis of target nucleic acid sequences.

摘要翻译： 本发明涉及通过使用固相上的单标记固定化探针的循环外源核解决反应（CER）或核酸外解反应（ER）检测靶核酸序列的新方法。 本发明能够使用单标记系统检测固相上的靶核酸序列。 与双标记等多标记体系相比，使用单标记探针的本发明在探针设计和制备中的便利性和成本效益方面具有优异的优点。 此外，反应期间信号变化的测量的测量负责更准确地定性和定量分析靶核酸序列。

公开(公告)号：US06820231B2

公开(公告)日：2004-11-16

申请号：US09866592

申请日：2001-05-30

申请人： Young Jo Lee ,  Young Cho Kim

发明人： Young Jo Lee ,  Young Cho Kim

IPC分类号： H03M1300

CPC分类号： H04L1/0016 ,  H04L1/0002 ,  Y02D50/10

摘要： Disclosed is a method of transmitting data in a communication system. A receiving part determines an optimum data transmission rate in accordance with the change of the channel environment of the receiving part, and provides the determined data transmission rate to a transmitting part. The transmitting part processes the data to be transmitted according to the transmitted optimum data transmission rate, and transmits the processed data to the receiving part. The transmitting part applies a different data coding rate or modulation type to the data to be transmitted in accordance with the determined data transmission rate. Since the optimum data transmission rate is determined in accordance with the change of the channel environment of the receiving part, an improved data throughput and re-transmission probability can be obtained with a reduced delay. Also, the insufficiency of memory capacity in the receiving part can be solved.

摘要翻译： 公开了一种在通信系统中发送数据的方法。 接收部分根据接收部分的信道环境的变化来确定最佳数据传输速率，并将确定的数据传输速率提供给传输部分。 发送部根据发送的最佳数据传输速率处理要发送的数据，并将处理的数据发送到接收部分。 发送部件根据确定的数据传输速率对要发送的数据应用不同的数据编码速率或调制类型。 由于根据接收部分的信道环境的变化确定最佳数据传输速率，所以可以以减小的延迟获得改进的数据吞吐量和重传概率。 此外，可以解决接收部分的存储容量不足。

公开(公告)号：US09683259B2

公开(公告)日：2017-06-20

申请号：US14394780

申请日：2013-04-16

申请人： Jong Yoon Chun ,  Young Jo Lee

发明人： Jong Yoon Chun ,  Young Jo Lee

IPC分类号： C12Q1/68 ,  C12Q1/34

CPC分类号： C12Q1/6823 ,  C12Q1/34 ,  C12Q1/6818 ,  C12Q2521/319 ,  C12Q2525/161 ,  C12Q2525/186 ,  C12Q2537/149 ,  C12Q2565/1015

摘要： The present invention relates to the detection of a target nucleic acid sequence by a PTO Cleavage and Extension-Dependent Signaling Oligonucleotide Cleavage assay (PCE-SC assay). The present invention is carried out in such a manner that the extended strand is produced on the CTO having arbitrary sequences as templates depending on the presence of target nucleic acid sequences and in turn the SO as probes is hybridized with the extended strand to give signal. The present invention employs a series of reactions including PTO hybridization and cleavage, CTO hybridization and extension, and SO hybridization and cleavage, which is responsible for the highly enhanced specificity of the present invention.

公开(公告)号：US20150167060A1

公开(公告)日：2015-06-18

申请号：US14394780

申请日：2013-04-16

申请人： Jong Yoon Chun ,  Young Jo Lee

发明人： Jong Yoon Chun ,  Young Jo Lee

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6823 ,  C12Q1/34 ,  C12Q1/6818 ,  C12Q2521/319 ,  C12Q2525/161 ,  C12Q2525/186 ,  C12Q2537/149 ,  C12Q2565/1015

摘要： The present invention relates to the detection of a target nucleic acid sequence by a PTO Cleavage and Extension-Dependent Signaling Oligonucleotide Cleavage assay (PCE-SC assay). The present invention is carried out in such a manner that the extended strand is produced on the CTO having arbitrary sequences as templates depending on the presence of target nucleic acid sequences and in turn the SO as probes is hybridized with the extended strand to give signal. The present invention employs a series of reactions including PTO hybridization and cleavage, CTO hybridization and extension, and SO hybridization and cleavage, which is responsible for the highly enhanced specificity of the present invention.

摘要翻译： 本发明涉及通过PTO切割和延伸依赖性信号寡核苷酸切割测定（PCE-SC测定）检测靶核酸序列。 本发明以这样的方式进行，即延伸链在具有任意序列作为模板的CTO上产生，取决于靶核酸序列的存在，并且随后探针与延伸链杂交，得到信号。 本发明采用了一系列包括PTO杂交和切割，CTO杂交和延伸的反应，以及SO杂交和切割，这是本发明高度增强的特异性。