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    Specific Co-Aggregation Inhibition by Arginine
    732.
    发明申请
    Specific Co-Aggregation Inhibition by Arginine 有权

    公开(公告)号：US20210196598A1

    公开(公告)日：2021-07-01

    申请号：US16649298

    申请日：2019-12-19

    Applicant: Colgate-Palmolive Company

    Inventor： Carlo DAEP ,  Harsh Mahendra TRIVEDI

    IPC: A61K8/44 ,  A61Q11/00 ,  C12Q1/18

    Abstract: Methods of selectively inhibiting co-aggregation of commensal and pathogenic bacteria in a population of bacteria that comprises commensal and pathogenic bacteria, such as in an individual's oral cavity are disclosed. Methods of reducing biofilm in an individual's oral cavity are disclosed. Methods of inhibiting biofilm formation in a population of bacteria that comprises commensal and pathogenic bacteria are disclosed. Methods of identifying a compound or composition that enhances the selective inhibition of coaggregation of commensal and pathogenic bacteria by arginine or an arginine oligomer are also disclosed. Methods of identifying a compound or composition that enhances the selective inhibition of biofilm formation of commensal and pathogenic bacteria by arginine or an arginine oligomer are disclosed.

    Oral Care Device with Sacrificial Electrode
    737.
    发明申请
    Oral Care Device with Sacrificial Electrode 有权

    公开(公告)号：US20210169624A1

    公开(公告)日：2021-06-10

    申请号：US17248413

    申请日：2021-01-25

    Applicant: Colgate-Palmolive Company

    Inventor： Patrik Johansson ,  Gerald Gontarz

    IPC: A61C19/06 ,  A61C17/00 ,  C25B11/02 ,  A61N1/05 ,  C25B1/00 ,  A46B15/00

    Abstract: A container, a toothbrush, or a device including at least one sacrificial electrode. In one aspect, the container may include a body adapted to contain an oral care solution and a cap selectively removable from the body. The cap may include a cavity configured to contain a fluid, a first electrode comprising a sacrificial metal, a second electrode spaced from the first electrode, and an electrical connection electrically connecting the first electrode and the second electrode to a power source. Activation of the power source may generate an electric field between the first and second electrodes, thereby causing the sacrificial metal of the first electrode to release ions into the fluid in the cavity of the cap.

    Toothbrush
    738.
    发明申请
    Toothbrush 有权

    公开(公告)号：US20210169207A1

    公开(公告)日：2021-06-10

    申请号：US17249055

    申请日：2021-02-18

    Applicant: Colgate-Palmolive Company

    Inventor： Chi Shing Wong ,  Douglas J. Hohlbein ,  Kenneth Waguespack ,  Al Sprosta ,  Wen Jin Xi ,  Xiangji Ding

    IPC: A46B5/02 ,  A46B9/04 ,  A46B15/00

    Abstract: An toothbrush having a handle and a head. The handle may include a first component and a second component covering at least a portion of the first component. The first and second components may be chemically compatible. The first and second components may both comprise a hard polyolefin. The first and second components may have different transparencies. In one aspect, the first component may be opaque and the second component may be transparent or semi-transparent. In some aspects, the handle may also include a third component comprising a thermoplastic elastomer. Furthermore, there may be at least one projection extending outwardly from an outer surface of the first component.

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