公开(公告)号：US20160354617A1

公开(公告)日：2016-12-08

申请号：US15117695

申请日：2015-02-04

申请人： ELEKTA AB (PUBL)

发明人： Per Carlsson

IPC分类号： A61N5/10

CPC分类号： A61N5/1082 ,  A61N5/103 ,  A61N5/1049 ,  A61N5/1067 ,  A61N2005/1061

摘要： An apparatus is disclosed, which comprises a radiotherapy delivery apparatus having a radiation source for emitting a beam of radiation and rotatable around an axis intersecting the beam through a range of at least x degrees, an imaging device, and a control unit for controlling the source and imaging device. The apparatus further comprises a treatment planning computer configured to receive a first image of a patient, and receive parameters defining the operations of the radiotherapy delivery apparatus. The parameters include an available range of rotation for the source defined as x-e, where e>0. The treatment planning computer is further configured to generate a treatment plan for the patient based on the received image and parameters. The control unit determines a patient position using the imaging device, determines a rotation r of the patient around the axis relative to the first image, and compensates for the rotation by offsetting the source by a rotation equal to r when r

摘要翻译： 公开了一种装置，其包括放射治疗递送装置，其具有用于发射辐射束的辐射源，并且能够围绕与光束交叉的轴线可旋转至少x度的范围，成像装置和用于控制源的控制单元 和成像装置。 该装置还包括治疗计划计算机，其被配置为接收患者的第一图像，并且接收限定放射治疗递送装置的操作的参数。 参数包括定义为x-e的源的可用旋转范围，其中e> 0。 治疗计划计算机还被配置为基于接收到的图像和参数来生成患者的治疗计划。 控制单元使用成像装置确定患者位置，确定患者围绕轴线相对于第一图像的旋转r，并且当r

公开(公告)号：USD773674S1

公开(公告)日：2016-12-06

申请号：US29504734

申请日：2014-10-08

申请人： ELEKTA AB (PUBL)

设计人： Erik Rurling ,  Anna Wik ,  Malin Svensson ,  Ivars Alksnis ,  Marianne Plantz ,  Mathias Stavervik

公开(公告)号：US20160074673A1

公开(公告)日：2016-03-17

申请号：US14851527

申请日：2015-09-11

申请人： ELEKTA AB (PUBL)

发明人： John Allen ,  Colin Winfield

IPC分类号： A61N5/10

CPC分类号： A61N5/1049 ,  A61B6/032 ,  A61N5/1036 ,  A61N5/1047 ,  A61N5/107 ,  A61N5/1081 ,  A61N5/1083 ,  A61N2005/1054 ,  A61N2005/1074

摘要： A radiotherapy apparatus comprises a source for producing a beam of ionising radiation along an axis, the beam covering a maximum aperture of the source, a collimator for collimating the beam to produce a collimated beam covering a sub-part of the maximum aperture, a patient support positioned in the path of the beam, a rotatable gantry, on which the source is mounted, for rotating the source around the patient support thereby to deliver the beam from a range of directions, an imaging device located opposite the source and with the patient support between the source and the imaging device, and mounted on the gantry via a drive member allowing translational motion of the imaging device in at least one direction perpendicular to the axis, and a control unit adapted to control the drive member to move the imaging device within the maximum aperture and maintain coincidence between the imaging device and the sub-part of the maximum aperture. Accordingly, the EPID can be moved during the treatment in order to maintain the collimated field of the radiation beam within the bounds of the EPID. This ensures that the image is valid and prevents damage to the EPID as a result of exposure of more sensitive (or less shielded) parts to the beam.

摘要翻译： 放射治疗装置包括用于产生沿着轴的电离辐射束的源，所述束覆盖源的最大孔径，用于准直光束以产生覆盖最大孔径的子部分的准直束的准直器，患者 定位在梁的路径中的支撑件，可旋转机架，源安装在该可旋转机架上，用于使源围绕患者支架旋转，从而从一系列方向输送束;成像装置，位于与源相对的位置，与病人 源和成像装置之间的支撑，并且经由驱动构件安装在台架上，驱动构件允许成像装置在垂直于轴线的至少一个方向上进行平移运动;以及控制单元，适于控制驱动构件以使成像装置 并且保持成像装置与最大光圈的子部分之间的重合。 因此，EPID可以在治疗期间移动，以便将辐射束的准直场保持在EPID的范围内。 这确保了图像有效，并且防止由于将更敏感（或更少屏蔽）的部件暴露于光束而导致对EPID的损坏。

公开(公告)号：US09271684B2

公开(公告)日：2016-03-01

申请号：US13956605

申请日：2013-08-01

申请人： Elekta AB (publ)

发明人： Christopher Knox ,  Colin Winfield ,  Kevin Brown

IPC分类号： A61B6/03 ,  A61B6/00 ,  A61N5/10

CPC分类号： A61B6/032 ,  A61B6/4233 ,  A61B6/466 ,  A61N2005/1061

摘要： An apparatus has a patient support, a rotatable gantry supporting a source of imaging radiation, and a radiation detector that operates in a cyclical pattern of an exposure phase followed by a readout phase. For a first detector cycle in which the gantry has a first angle of rotation, the source of radiation is controlled to emit a first radiation beam pulse during the exposure phase, and respective first imaging data is read out during the readout phase. For a second, subsequent detector cycle, it is determined if the gantry has rotated through at least a threshold angular displacement relative to said first angle of rotation, and if so, the source of radiation is controlled to emit a second radiation beam pulse during the exposure phase, and respective second imaging data is read out during the readout phase.

摘要翻译： 一种装置具有患者支撑件，支撑成像辐射源的可旋转机架以及以曝光阶段的周期性图案操作的辐射检测器，随后是读出阶段。 对于其中机架具有第一旋转角度的第一检测器循环，在曝光阶段期间控制辐射源发射第一辐射束脉冲，并且在读出阶段期间读出相应的第一成像数据。 对于第二个随后的检测器周期，确定台架是否相对于所述第一旋转角度旋转了至少一个阈值角位移，如果是，则控制辐射源在第二辐射束脉冲期间发射第二辐射束脉冲 曝光阶段，并且在读出阶段期间读出各自的第二成像数据。

公开(公告)号：US09269137B2

公开(公告)日：2016-02-23

申请号：US13927391

申请日：2013-06-26

申请人： Elekta AB (Publ)

发明人： Colin Winfield ,  Abdul Sayeed

IPC分类号： G06K9/00 ,  G06T7/00 ,  A61N5/10

CPC分类号： G06T7/0012 ,  A61N5/1071 ,  A61N2005/1054 ,  G06F17/30259 ,  G06F19/00 ,  G06F19/321 ,  G06F19/3481 ,  G06K9/6202 ,  G06T2207/10004 ,  G06T2207/10116 ,  G16H20/40 ,  G16H30/20 ,  G16H50/20

摘要： Embodiments of the invention provide systems and methods for evaluating treatment parameters for a patient undergoing radiotherapy. The method includes the step of generating a portal dosimetry image showing differences between a planning image obtained prior to a treatment session and a portal image obtained during the treatment session. A database of prior portal dosimetry results is accessed, and a processor is used to perform a similarity measurement between the portal dosimetry image and the prior portal dosimetry results. Based on the similarity measurement, the system determines whether radiation was delivered as planned during the treatment session.

摘要翻译： 本发明的实施例提供了用于评估经历放射治疗的患者的治疗参数的系统和方法。 该方法包括生成门诊剂量测定图像的步骤，该图像显示在治疗会话之前获得的规划图像与在治疗期间获得的门静图像之间的差异。 访问先前门户剂量测定结果的数据库，并且处理器用于在门户剂量测定图像和先前的门户剂量测定结果之间执行相似性测量。 根据相似性测量，系统确定在治疗期间辐射是否按计划传送。

公开(公告)号：US20140321615A1

公开(公告)日：2014-10-30

申请号：US14266622

申请日：2014-04-30

申请人： Elekta AB (Publ)

发明人： Per Carlsson

IPC分类号： A61N5/10

CPC分类号： A61N5/1067 ,  A61B6/032 ,  A61N5/1049 ,  A61N5/107 ,  A61N5/1081 ,  A61N2005/1061

摘要： A radiotherapy apparatus comprises a rotatable gantry, supporting a source of therapeutic radiation and a source of diagnostic radiation, the two sources being rotationally (or angularly) spaced apart around a rotation axis of the gantry, with at least one collimator associated with the source of therapeutic radiation and arranged to limit the cross-sectional area of a beam produced by that source, a control means arranged to conduct a treatment fraction using the apparatus by causing the apparatus to i. acquire images of a patient using the source of diagnostic radiation, ii. retain those images at least temporarily, iii. subsequently, after further rotation of the gantry, select a retained image acquired when the source of diagnostic radiation was at a rotational position corresponding to the instantaneous rotational position of the source of therapeutic radiation, and iv. control the beam relative to the patient using information derived from the selected image. The corresponding rotational position is ideally one in which the source of therapeutic radiation is at the same or substantially the same rotational position as was the source of diagnostic radiation at the point in time when the image was acquired. An alternative a radiotherapy apparatus comprises a rotatable gantry supporting a source of therapeutic radiation and a source of diagnostic radiation, at least one collimator associated with the source of therapeutic radiation and arranged to limit the cross-sectional area of a beam produced by that source, a reconstruction means arranged to i. obtain two-dimensional images of a patient using the source of diagnostic radiation, ii. retain those images at least temporarily, iii. apply a recency threshold to the retained images thereby to exclude images less recent than the threshold, iv. select at least three such retained images meeting the recency threshold and reconstruct a CT volume or tomographic image using the selected images, and a control means arranged to conduct a treatment fraction or treatment session using the apparatus, controlling the collimator using information derived from the CT volume.

公开(公告)号：US20140275707A1

公开(公告)日：2014-09-18

申请号：US14212134

申请日：2014-03-14

申请人： Elekta AB Publ.

发明人： Mattias LIDSTRÖM ,  Malcolm Williams ,  Bartosz Gorka ,  Rui Chen ,  Thomas Arn

IPC分类号： A61N5/10 ,  A61B19/00

CPC分类号： A61N5/1049 ,  A61B34/20 ,  A61B90/14 ,  A61B2017/00119 ,  A61B2034/2055 ,  A61B2090/3937 ,  A61B2090/3945 ,  A61N5/1067 ,  A61N2005/1051 ,  A61N2005/1059 ,  A61N2005/1097

摘要： The present invention relates to the field of radiation therapy. In particular, the invention concerns systems and methods for monitoring intra-fraction motions of patients in connection with treatment cancer in radiation therapy system. A patient marker is attached on the nose of the patient and images of the patient marker and reference markers is captured at predetermined time intervals. The reference markers are arranged in defined positions relative to a patient fixation arrangement for fixation of the patient during treatment. A position of the patient marker relative the reference markers is determined based on images captured by an optical tracking system, wherein changes in the position provide information if the patient or a part of the patient has moved.

摘要翻译： 本发明涉及放射治疗领域。 特别地，本发明涉及用于监测与辐射治疗系统中的治疗癌症相关的患者的部分内运动的系统和方法。 将患者标记附着在患者的鼻子上，并以预定的时间间隔捕获患者标记和参考标记的图像。 参考标记被布置在相对于患者固定装置的限定位置，用于在治疗期间固定患者。 基于由光学跟踪系统拍摄的图像确定患者标记物相对于参考标记的位置，其中，如果患者或患者的一部分已经移动，则位置的改变提供信息。

公开(公告)号：US20130188767A1

公开(公告)日：2013-07-25

申请号：US13743610

申请日：2013-01-17

申请人： Elekta AB (publ)

发明人： Per Carlsson

IPC分类号： A61B6/00 ,  A61B6/03

CPC分类号： A61B6/542 ,  A61B6/032 ,  A61B6/035 ,  A61N5/1037

摘要： Intra-fraction movement of the patient puts at risk sensitive regions that are near to a radiation dose. In a radiotherapy system that delivers a dose as a series of discrete sub-doses, an initial CT scan is performed to determine the patient's position, after which the sub-doses that are directed to regions within a preset distance of a sensitive structure are performed first, while the sub-doses directed to regions that are more remote from a sensitive structure are performed later.

摘要翻译： 患者的部分内运动放置在接近辐射剂量的风险敏感区域。 在以一系列离散子剂量递送剂量的放射治疗系统中，执行初始CT扫描以确定患者的位置，之后执行针对敏感结构的预设距离内的区域的子剂量 首先，针对远离敏感结构的区域的子剂量稍后进行。

公开(公告)号：US20130034211A1

公开(公告)日：2013-02-07

申请号：US13647512

申请日：2012-10-09

申请人： ELEKTA AB (PUBL)

发明人： Bengt Åke Claesson

IPC分类号： A61N5/10

CPC分类号： A61N5/1045

摘要： Radiotherapy apparatus is disclosed, comprising a radiation source capable of emitting a beam of therapeutic radiation along a beam axis, collimation apparatus for delimiting the beam and comprising (i) a block of sufficient width to extend across the width of the beam, selectively movable into the beam from a first side of the beam axis, and (ii) an array of individually moveable elongate narrow leaves arranged side-by-side in a direction perpendicular to the beam, each being moveable longitudinally into the beam from a second and opposing side of the beam axis, in which there is no array of individually moveable elongate narrow leaves arranged side-by-side in a direction perpendicular to the beam moveable longitudinally into the beam from the first side of the beam axis. Thus, there is in effect a single bank of MLC leaves on one side of the aperture and a block collimator on the other.

摘要翻译： 公开了放射治疗装置，其包括能够沿着光束轴发射治疗辐射束的辐射源，用于限定光束的准直装置，并且包括（i）足够宽度的块以跨过光束的宽度延伸，可选择性地移动到 所述光束从所述光束轴线的第一侧起，以及（ii）在垂直于所述光束的方向上并排布置的可单独移动的细长窄叶片的阵列，每个可从第二和相对侧纵向移动到所述光束中 其中在垂直于梁的方向上并排设置有可从纵向轴线的第一侧纵向移动到梁中的单独可移动细长窄叶片的阵列。 因此，实际上，一个单一的MLC叶片在孔的一侧留下，另一个是块准直器。

公开(公告)号：US11847721B2

公开(公告)日：2023-12-19

申请号：US16623660

申请日：2018-06-21

申请人： Elekta AB (publ)

发明人： Jonas Anders Adler ,  Ozan Öktem

IPC分类号： G06T11/00 ,  G16H30/00

CPC分类号： G06T11/006 ,  G06T11/005 ,  G06T11/008 ,  G16H30/00 ,  G06T2210/41 ,  G06T2211/424

摘要： Much of the image processing that is applied to medical images is a form of “inverse problem”. This is a class of mathematical problems in which a “forward” model by which a signal is converted into dataset is known, to at least some degree, but where the aim is to reconstruct the signal given the resulting dataset. Thus, an inverse problem is essentially seeking to discover x given knowledge of A(x)+noise by finding an appropriate reconstruction operator A† such that A† (A(x)+noise)≈x, thereby enabling us to obtain x (or a close approximation) given knowledge of an output dataset consisting of A(x)+noise. Generally, several such processes (or their equivalents) are applied to the image dataset. If the first process (for example, noise reduction) is expressed via a first reconstruction operator A1† characterised by a parameter set Θ1 and the second process (for example, segmentation) is expressed via a second reconstruction operator A2† characterised by a parameter set Θ2, then the result of the two steps applied consecutively is A2† (A1†(y)). This can be expressed as an overall reconstruction operator P+, characterised by a parameter set Φ. If we then allow a machine learning process to optimise P+, then the steps previously carried out separately can be combined into a single optimisation. This yields advantages in terms of computational load and in the accuracy of the end result.