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公开(公告)号:US12258351B2
公开(公告)日:2025-03-25
申请号:US18625188
申请日:2024-04-02
Applicant: KUNMING UNIVERSITY OF SCIENCE AND TECHNOLOGY
Inventor: Min Xu , Shaoxing Dai
IPC: C07D493/10 , A61K31/35 , A61P31/14
Abstract: A sesquiterpenoid derivative and use thereof in preparing a broad-spectrum antiviral drug provided. The sesquiterpenoid derivative can stimulate heterogeneous nuclear ribonucleoprotein A2/B1, activate the cell signal pathway of TANK-binding kinase 1-interferon regulatory factor 3, and increase the expression and secretion of endogenous type I interferon. As a result, it can inhibiting various viruses and can be used as a broad-spectrum antiviral drug for preventing or treating various viral infectious diseases and symptoms, including Covid-19, vesicular stomatitis virus VSV-G, AIDS virus, hepatitis C virus, Japanese encephalitis virus, influenza virus, poliovirus, Coxsackie virus, dengue virus, rotavirus, tobacco mosaic virus, measles virus, mumps virus, Ebola virus, Marburg virus, herpes virus and adenovirus. Sesquiterpenoid derivatives can be made as a raw material into oral dosage form such as tablet, capsule and dripping pill, or clinically acceptable pharmaceutical preparation such as inhalant and injection.
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72.
公开(公告)号:US20250086365A1
公开(公告)日:2025-03-13
申请号:US18955880
申请日:2024-11-21
Applicant: Kunming University of Science and Technology
Inventor: Zhouhang Li , Genxian Yang , Yuling Zhai , Hua Wang
IPC: G06F30/28 , G06F113/08 , G06F119/08
Abstract: The present disclosure provides a method for designing a supercritical heat exchanger based on pseudo-phase transition partition. The method mainly includes the following steps: inputting boundary conditions of a heat exchanger; calculating an upper boundary temperature and a lower boundary temperature of a pseudo-phase transition region; calculating a temperature of an inner wall surface of a supercritical fluid; determining an upper boundary temperature of a pseudo-superheated condensation region; and dividing the heat exchanger into four sections on the basis of above three boundary temperatures and inlet and outlet temperatures, and calculating the section size and the total size of the heat exchanger. According to the method, the automatic partition determination of single-phase cooling and pseudo-superheated condensation in a supercritical air cooler can be realized, requiring no division of the heat exchanger according to equal enthalpy change or equal length, and the calculation is rapid and accurate.
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公开(公告)号:US12230799B1
公开(公告)日:2025-02-18
申请号:US18816719
申请日:2024-08-27
Applicant: KUNMING UNIVERSITY OF SCIENCE AND TECHNOLOGY
Inventor: Feng Liang , Pan Liu , Minjie Hou , Da Zhang , Bin Yang
IPC: H01M4/583 , H01M4/02 , H01M4/04 , H01M10/054
Abstract: A method for preparing a carbon nanotube sodiophilic metal anode-free sodium metal battery electrode material is provided, and the method includes the following steps: the carbon nanotubes are modified by a dielectric barrier plasma device; the modified carbon nanotubes are mixed and stirred with a sodiophilic metal salt to obtain a precursor slurry; the precursor slurry is dried, placed in a tube furnace after drying, and heated by introducing a reducing gas to react, thereby obtaining a carbon nanotube sodiophilic metal anode-free sodium metal battery electrode material. The electrode material prepared by the method has a stable structure, excellent electrical conductivity, and excellent sodium affinity, and can be applied to anode-free sodium metal battery electrode materials. The entire preparation process is controllable, the synthesis cycle is short, and the operation is simple.
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公开(公告)号:US20250012029A1
公开(公告)日:2025-01-09
申请号:US18422121
申请日:2024-01-25
Applicant: HUANENG LANCANG RIVER HYDROPOWER INC. , HOHAI UNIVERSITY , KUNMING UNIVERSITY OF SCIENCE AND TECHNOLOGY
Inventor: Hao CHEN , Haibin XIAO , Tengfei BAO , Daming ZHU , Yingchi MAO , Wei ZENG , Zhiyong ZHAO , Minglong YANG , Xu CHEN , Zhiting CHEN , Hua LIU , Guangyou SHI , Libing ZHANG , Haojiang ZHANG , Zhen GUAN , Fengyu XIE , Shunbo WANG , Xiaokun XU , Chenglong XIONG , Haifeng GUO
Abstract: The partition monitoring method for concrete dam operation key parts provided by the disclosure firstly utilizes the extracted monitoring data time-frequency vector to partition the concrete dam key parts, and on this basis, obtains time series measurement data of different types of monitoring instruments with high temporal and spatial correlation, so as to establish a graph structure. Then, the dependence of time dimension and variable dimension of multivariate time series data is captured, and the relationship between further learning and representation of graph attention network is provided. Furthermore, the final feature representation of time series measured data is obtained, and finally the anomaly score is calculated through the final feature representation to detect anomalies. The complementary mutual verification of multiple measuring points of monitoring instruments with various types is realized. The structural integrity and spatial distribution law of concrete dams are fully embodied.
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公开(公告)号:US20240332495A1
公开(公告)日:2024-10-03
申请号:US18346970
申请日:2023-07-05
Applicant: KUNMING UNIVERSITY OF SCIENCE AND TECHNOLOGY
Inventor: FENG LIANG , PENG DONG , DA ZHANG
CPC classification number: H01M4/0459 , H01M4/625 , H01M2004/021 , H01M2004/028
Abstract: A method for treating battery positive electrode material includes: cold plasma treatment of at least part of the battery positive electrode material with carbon layer on the surface to be treated to have active particles doped in the carbon layer, where the doping amount is not less than 50 ppm (Part per million). At least part of the surface of the positive electrode material of the battery contains a carbon layer and at least part of the surface has a rod-like shape. The carbon layer is a carbon layer doped with active particles after cold plasma treatment, and a high-sodium ion conductance NaF layer is formed on the surface of the positive electrode material.
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76.
公开(公告)号:US20240222697A1
公开(公告)日:2024-07-04
申请号:US18537953
申请日:2023-12-13
Applicant: KUNMING UNIVERSITY OF SCIENCE AND TECHNOLOGY , JIANGSU FENGCHI CARBON BASED NEW MATERIAL RESEARCH INSTITUTE CO., LTD
Inventor: FENG LIANG , MINJIE HOU , DA ZHANG , TAO ZHANG , SUNZU XIANG , WENLONG JIANG , BAOQIANG XU , BIN YANG
IPC: H01M10/0562
CPC classification number: H01M10/0562 , H01M2300/0068
Abstract: A method for preparing a sodium super ionic conductor solid electrolyte by low-dimensional crystallization belongs to a field of energy materials. The method is based on the theory of negative ion coordination polyhedron growth unit, and uses low-temperature plasma as a protective gas of a spray drying equipment. While evaporating the solvent in a sodium super ionic conductor solid electrolyte precursor slurry, plasma active groups modify the particle surface of the sodium super ionic conductor solid electrolyte precursor particles in-situ. A free space dimension of crystal growth in the crystallization process is reduced, and directional growth of crystals in the solid phase sintering process is induced. Secondly, the dispersion stability of the sodium super ionic conductor solid electrolyte precursor particles is improved. Compared with the traditional high-temperature solid-state sintering process, the method has the advantages of fast crystallization speed, high crystal purity and integrity, good compactness, and uniform particles.
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公开(公告)号:US11981569B2
公开(公告)日:2024-05-14
申请号:US18304316
申请日:2023-04-20
Applicant: KUNMING UNIVERSITY OF SCIENCE AND TECHNOLOGY
Inventor: Feng Liang , Zhipeng Xie , Da Zhang
Abstract: A method includes the following steps: a first step: the material containing heteroatom and graphite powder are mixed for a preset time by grinding, and the molar ratio of heteroatom to carbon atom is 1%-10%, then the heteroatom precursors are obtained; a second contact step: the heteroatom precursor is filled into a graphite rod with holes and compacted, then the graphite rod is dried for a preset time to obtain a plasma anode and using a DC arc plasma device to prepare the graphite anode into heteroatom-doped CNHs; a third contact step: the heteroatom-doped CNHs are dispersed in a reducing solution, a platinum salt is added to stir evenly, the reduction reaction is carried out by heating and stirring, and after centrifugation, washing and drying, a catalyst with platinum loading is obtained.
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公开(公告)号:US20240124998A1
公开(公告)日:2024-04-18
申请号:US18397411
申请日:2023-12-27
Applicant: KUNMING UNIVERSITY OF SCIENCE AND TECHNOLOGY
Inventor: Yun LEI , Shiding WANG , Dongfang YANG , Wenhui MA , Zhanchao LI , Yakun ZHANG
CPC classification number: C25C3/28 , C22B34/1277 , C22B34/1295
Abstract: The titanium-containing oxide slag, low-purity silicon and slagging fluxes are subject to reduction smelting together, and a bulk Si—Ti intermediate alloy is obtained by slag-metal separation; the obtained bulk Si—Ti intermediate alloy is crushed into Si—Ti intermediate alloy particles; and the obtained Si—Ti intermediate alloy particles are used as an anode, metallic molybdenum or metallic nickel as a cathode, metallic titanium as a reference electrode, and NaCl—KCl—NaF together with small amounts of Na3TiF6 or K3TiF6 as a molten salt, to carry out the electrolysis under a high-purity argon atmosphere at a temperature of 973 K. Ti in the Si—Ti intermediate alloy particles dissolved at the anode and deposited at the cathode, while Si in the Si—Ti intermediate alloy particles fell off from the anode as metallic silicon powder.
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公开(公告)号:US11958789B1
公开(公告)日:2024-04-16
申请号:US18536550
申请日:2023-12-12
Applicant: Kunming University of Science and Technology
Inventor: Zhi-quan Yang , Jun-fan Xiong , Ying-yan Zhu , Yi Yang , Yong-shun Han , Muhammad Asif Khan , Jian-bin Xie , Tian-bing Xiang , Bi-hua Zhang , Han-hua Xu , Jie Zhang , Shen-zhang Liu , Qi-jun Jia , Cheng-yin Ye , Gang Li
IPC: C04B7/36
CPC classification number: C04B7/361
Abstract: A method for determining a consistency coefficient of a power-law cement grout includes: determining a water-cement ratio of the power-law cement grout; according to engineering practice requirements, determining a time required to determine the consistency coefficient of the power-law cement grout; and obtaining the consistency coefficient of the power-law cement grout. The method is accurate and reliable, requires less calculation, etc.; and has very high practical value and popularization value in environmental protection and ecological restoration.
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公开(公告)号:US11850659B2
公开(公告)日:2023-12-26
申请号:US17486062
申请日:2021-09-27
Applicant: KUNMING UNIVERSITY OF SCIENCE AND TECHNOLOGY
Inventor: Hongxi Liu , Jingzhou Liu , Xuanhong Hao , Yingnan Di , Jianquan Lin
CPC classification number: B22F1/054 , B22F1/107 , B23K26/0006 , B23K26/34 , B23K26/60 , C22C30/00 , C23C24/103 , C23C24/106 , B22F2301/15
Abstract: The present disclosure discloses a high-entropy alloy powder for laser cladding and a use method thereof. The alloy powder is CoCrFeMnNiCx, and x has a value of 0.1-0.15. The specific method includes: subjecting a 45 steel substrate to surface pretreatment, mixing the weighed CoCrFeMnNi high-entropy alloy powder with different content of a nano-C powder uniformly and pre-placed on the pre-treated substrate surface to form a prefabricated layer, then placing the prefabricated layer at 80-90° C. for constant temperature treatment for 8-12 h, and under a protective atmosphere, subjecting the cladding powder to laser cladding on the surface of the 45 steel. The method of the present disclosure prepares a CoCrFeMnNiCx high-entropy alloy coating with performance superior to the CoCrFeMnNi high-entropy alloy coating.
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