公开(公告)号：US10960131B2

公开(公告)日：2021-03-30

申请号：US15461727

申请日：2017-03-17

Applicant: MEDIMOP Medical Projects Ltd.

Inventor： Oz Cabiri ,  Reuven Y. Filman ,  Yossi Bar-El

IPC: A61M5/145 ,  A61M5/142 ,  A61M5/14 ,  A61M5/315 ,  A61M5/168 ,  A61M5/172

Abstract: An assembly of a drug delivery system, comprising: a first component; a second component which is configured to move linearly with respect to the first component; and, a resistance element configured to resist linear movement during transport of the first component with respect to the second component in a closed transport configuration but which is adapted to be overcome during nominal operation of the drug delivery system.

公开(公告)号：US10376647B2

公开(公告)日：2019-08-13

申请号：US15074412

申请日：2016-03-18

Applicant: MEDIMOP Medical Projects Ltd.

Inventor： Jason W. Farris ,  Jorge Santos ,  Tommy Gene Davis

IPC: A61M5/315 ,  F16H25/20

Abstract: An injection assembly includes a housing with a barrel positioned within the housing. The barrel includes an axis extending from a proximal end to a distal end thereof and a chamber for storing medicine. An elongate anti-rotation shaft is rotationally fixed to the housing and has a non-circular cross-section. The injection assembly includes an inner screw having an inner screw opening to complementarily receive the anti-rotation shaft to prevent rotation of the inner screw with respect to the anti-rotation shaft but allow respective linear translation along the axis. An outer screw is positioned within, and rotatable with respect to, the housing and has an outer screw opening to threadably receive the inner screw, wherein rotation of the outer screw translates the inner screw along the axis and along the anti-rotation shaft. A plunger is coupled to the distal end of the inner screw and is moveable with respect to the chamber to push the medicine out of the chamber when the outer screw is rotated.

公开(公告)号：US10350365B2

公开(公告)日：2019-07-16

申请号：US15655068

申请日：2017-07-20

Applicant: MEDIMOP Medical Projects Ltd.

Inventor： Yossi Gross ,  Oz Cabiri

IPC: A61M5/14 ,  A61M5/31 ,  A61M5/142 ,  A61M5/145 ,  A61M5/158 ,  A61M5/168 ,  A61M5/172 ,  A61M5/315 ,  F16H25/12

Abstract: Apparatus is described for administering a substance to a subject. A vial contains the substance and a stopper is disposed within the vial and is slidably coupled to the vial. A first threaded element is (a) rotatable with respect to the vial and (b) substantially immobile proximally with respect to the vial during rotation of the first threaded element. A second threaded element is threadedly coupled to the first threaded element. At least a distal end of the second threaded element is substantially non-rotatable with respect to the vial, and the distal end of the second threaded element defines a coupling portion that couples the second threaded element to the stopper. The first threaded element, by rotating, linearly advances the stopper and at least the distal end of the second threaded element toward a distal end of the vial. Other embodiments are also described.

公开(公告)号：US10299990B2

公开(公告)日：2019-05-28

申请号：US15653610

申请日：2017-07-19

Applicant: MEDIMOP Medical Projects Ltd.

Inventor： Nimrod Lev ,  Niv Ben Shalom

IPC: A61J1/20 ,  A61J1/14 ,  A61J1/10

Abstract: Liquid drug transfer devices with universal drug vial adapters for use with a drug vial of a small drug vial and a large drug vial. Some universal drug vial adapters employ the same generally opposite upright flex members for clamping a small drug vial and a large drug vial. Other universal drug vial adapters include a set of minor flex members for clamping a small drug vial and a set of major flex members encircling the set of minor flex members for clamping a large drug vial whereupon the large drug vial underlies the set of minor flex members. Liquid drug transfer devices with a universal injection port connector for attachment on an injection port of an infusion bag.

公开(公告)号：US10159785B2

公开(公告)日：2018-12-25

申请号：US14593041

申请日：2015-01-09

Applicant: MEDIMOP Medical Projects Ltd.

Inventor： Oz Cabiri

IPC: A61M5/142 ,  A61M5/28 ,  A61M5/24 ,  A61M5/145 ,  A61M5/31 ,  A61M5/158 ,  A61M5/172 ,  A61J1/14

Abstract: A method and apparatus are disclosed for delivery of a drug to a recipient. In some embodiments, the delivery apparatus may unseal a drug containing reservoir. In some embodiments, the delivery rate may be controlled and/or adjustable. Optionally the apparatus may be disposable. Optionally, the apparatus may have a low profile and/or be wearable and/or attachable to the recipient. Optionally, discharge of the drug and/or unsealing of the reservoir may be driven by a plunger moving parallel to the base of the apparatus. Optionally, the apparatus may release a hypodermic needle into the recipient. Optionally, release of the hypodermic needle may be in a direction non-parallel and/or orthogonal to the direction of movement of the plunger. Optionally, prior to release, the hypodermic needle may be preserved in an aseptic state by a needle opening septum sealing a needle opening. Optionally, upon release, the hypodermic needle may pierce the needle opening septum.

公开(公告)号：US10086145B2

公开(公告)日：2018-10-02

申请号：US15269248

申请日：2016-09-19

Applicant: MEDIMOP Medical Projects Ltd.

Inventor： Oz Cabiri ,  Ran Hezkiahu

IPC: A61M5/315 ,  A61M5/145 ,  A61M5/142 ,  A61M5/31

Abstract: A method and system are disclosed for driving a plunger in a drug reservoir. In some embodiments, a variable friction element interconnects between a pushing shaft and a wall of the reservoir. For example, rotation of a driving element in a first direction relative to the pushing shaft may advance the pushing shaft in the reservoir. The friction element may have increased friction resistance to rotation of the pushing shaft in the first direction in comparison to frictional resistance to advancing the pushing shaft. For example, the increased friction may result from wedging a radial element between the pushing shaft and the wall of the reservoir.

公开(公告)号：US10071198B2

公开(公告)日：2018-09-11

申请号：US13667739

申请日：2012-11-02

Applicant: MEDIMOP Medical Projects Ltd.

Inventor： Oz Cabiri ,  Reuven Y. Filman ,  Boris Degtiar

IPC: A61M5/158 ,  A61M5/142

CPC classification number: A61M5/158 ,  A61M5/14248 ,  A61M2005/14252 ,  A61M2205/13

Abstract: A variable flexibility adhesive system may adhere a surface of a medical infusion device to the skin of a user. The system may be configured to hold a location on the surface stationary with respect to a site on the user's skin. The system may include an adhesive substrate for adhering to the user and an interface where the substrate is held to the surface of the device. The interface may totally and/or partially surround the stationary location. A skirt of the substrate may totally and/or partially surround the interface. Parts of the skirt may be stiffened. Optional features may include tabs for activation of the adhesive and/or a location for peeling the infuser away from the skin. Additionally or alternatively, the interface may have variable flexibility. Additionally or alternatively, the stiffener may include a plastic layer.

公开(公告)号：US20180193228A1

公开(公告)日：2018-07-12

申请号：US15741548

申请日：2016-07-01

Applicant: MEDIMOP Medical Projects Ltd.

Inventor： Uri DAVID ,  Igor DENENBURG

IPC: A61J1/20

CPC classification number: A61J1/2096 ,  A61J1/201 ,  A61J1/2055 ,  A61J1/2065

Abstract: A liquid drug transfer device that includes a vial adapter having at least two non-adjacent vial retention flex members and at least two non-adjacent vial guidance flex members. The vial guidance flex members are each provisioned with a purpose design hinged zone distanced from a vial adapter top wall for intentionally being hinged thereat on telescopic snap fitting on an injection vial. The vial retention flex members can double as vial guidance flex members with the condition that their hinged zones are distal to their inwardly protruding vial retention ribs relative to the vial adapter top wall.

公开(公告)号：US09987432B2

公开(公告)日：2018-06-05

申请号：US14861478

申请日：2015-09-22

Applicant: MEDIMOP Medical Projects Ltd.

Inventor： Oz Cabiri ,  Ran Hezkiahu

IPC: A61M5/315 ,  A61M5/142 ,  A61M5/31

CPC classification number: A61M5/31515 ,  A61M5/142 ,  A61M5/14248 ,  A61M5/1452 ,  A61M5/31501 ,  A61M5/31511 ,  A61M5/31565 ,  A61M5/31583 ,  A61M5/31586 ,  A61M2005/3123

Abstract: A method and system are disclosed for driving a plunger in a drug reservoir. In some embodiments, a variable friction element interconnects between a pushing shaft and a wall of the reservoir. For example, rotation of a driving element in a first direction relative to the pushing shaft may advance the pushing shaft in the reservoir. The friction element may have increased friction resistance to rotation of the pushing shaft in the first direction in comparison to frictional resistance to advancing the pushing shaft. For example, the increased friction may result from wedging a radial element between the pushing shaft and the wall of the reservoir.

公开(公告)号：US20180056009A1

公开(公告)日：2018-03-01

申请号：US15254638

申请日：2016-09-01

Applicant: MEDIMOP Medical Projects Ltd.

Inventor： Reuven Y. FILMAN ,  Yossi BAR-EL

IPC: A61M5/315 ,  A61M5/32

CPC classification number: A61M5/31548 ,  A61M5/14248 ,  A61M5/31501 ,  A61M5/31515 ,  A61M5/31576 ,  A61M5/3287 ,  A61M2005/14252 ,  A61M2005/206 ,  A61M2005/31518 ,  A61M2005/3152 ,  A61M2005/31588 ,  A61M2207/00

Abstract: Drug delivery devices of a standard size are adapted for injecting different doses. The device comprises an injection needle, a reservoir having an available volume, and a plunger for evacuating the volume into the needle for injection. A spacer is placed with the plunger in the reservoir to take up some of the available volume and leave a residual amount of available volume in the reservoir to correspond to a currently desired dose size. The spacer may be selected from different sizes corresponding to different doses.