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公开(公告)号:US11129814B2
公开(公告)日:2021-09-28
申请号:US16053537
申请日:2018-08-02
发明人: Edmond J. LaVoie , Ajit Parhi , Daniel S. Pilch , Yongzheng Zhang , Malvika Kaul
IPC分类号: C07D417/12 , A61K31/428 , C07D277/64 , C07D513/04 , C07C235/88 , C07D413/12 , C07D413/14 , C07D417/14 , A61K31/166 , A61K31/437 , A61K31/4439 , A61K31/454 , A61K31/4545 , A61K31/497
摘要: The invention provides synthetic methods and synthetic intermediates that are useful for preparing the antibacterial compound:
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公开(公告)号:US11118011B2
公开(公告)日:2021-09-14
申请号:US16240091
申请日:2019-01-04
发明人: Joachim B. Kohn , Durgadas Bolikal
摘要: The present invention relates to new classes of monomeric compounds, which may be polymerized to form novel biodegradable and bioresorble polymers and copolymers. These polymers and co-polymers, while not limited thereto, may be adapted for radio-opacity and are useful for medical device applications and controlled release therapeutic formulations.
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公开(公告)号:US11113966B2
公开(公告)日:2021-09-07
申请号:US17100478
申请日:2020-11-20
发明人: Marco Gruteser , Suhas Mathur
摘要: Disclosed is a method and system that receives sensor information from each of a plurality of sensors. Each sensor in the plurality is associated with a vehicle. The sensor information includes location coordinates of each vehicle in the plurality. The sensor information associated with each vehicle in the plurality then is translated to parking statistics information. In one embodiment, the translation is based on an aggregate of sensor information corresponding to the plurality of vehicles. The system then communicates parking statistics information to the vehicle.
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公开(公告)号:US20210264574A1
公开(公告)日:2021-08-26
申请号:US17318363
申请日:2021-05-12
摘要: A device to correct an image blur within a medical image is described. An image analysis application executed by the device receives the medical image from a medical image provider. Next, the image blur is detected within the medical image by analyzing the medical image. The medical image is subsequently processed with a deep learning model to correct the image blur. In response to the processing, a de-blurred medical image is generated. The de-blurred medical image is provided for a presentation or a continued analysis.
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公开(公告)号:US11098175B2
公开(公告)日:2021-08-24
申请号:US15900137
申请日:2018-02-20
发明人: Thomas Nosker , Jennifer Lynch , Justin Hendrix , Bernard Kear , Gordon Chiu , Stephen Tse
摘要: A method for forming a graphene-reinforced polymer matrix composite is disclosed. The method includes distributing graphite microparticles into a molten thermoplastic polymer phase; and applying a succession of shear strain events to the molten polymer phase so that the molten polymer phase exfoliates the graphite successively with each event until at least 50% of the graphite is exfoliated to form a distribution in the molten polymer phase of single- and multi-layer graphene nanoparticles less than 50 nanometers thick along the c-axis direction.
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公开(公告)号:US11069890B2
公开(公告)日:2021-07-20
申请号:US16306354
申请日:2017-05-31
发明人: Maria S. Tomassone , Kurt B. Smith
IPC分类号: C01B32/198 , B01F3/08 , B01J13/08 , B01J13/20 , H01M4/36 , H01M4/48 , B82Y30/00 , B82Y40/00 , H01M4/02
摘要: The present invention relates to methods of fabrication of hollow shells/spheres/particles, core-shell particles and composite materials made from these particles.
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公开(公告)号:US20210218096A1
公开(公告)日:2021-07-15
申请号:US17214290
申请日:2021-03-26
IPC分类号: H01M50/186 , H01M50/169 , H01G11/80 , H01G11/68 , H01G11/52 , H01G11/32
摘要: A hermetic seal for electrochemical cells. The seal is formed between first and second electronically conductive barrier members. The seal is formed by a cold weld between the first and second barrier members. At least one of the first barrier member and the second barrier member are configured to function as current collectors.
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公开(公告)号:US20210213067A1
公开(公告)日:2021-07-15
申请号:US17150457
申请日:2021-01-15
发明人: Yufang Shi , Guangwen Ren , Liying Zhang
IPC分类号: A61K35/28 , A61K38/21 , C12N5/0775 , A61K45/06 , A61K38/19 , A61K38/20 , A61P37/02 , C12N5/074 , C12N5/00
摘要: The present invention provides methods or kits with inflammatory cytokines to pretreat 1-ISCs to augment their immune modulatory effect, in prevention and treatment of various diseases such as multiple sclerosis, arthritis, lupus, sepsis, hepatitis, cirrhosis, Parkinson's disease, chronic infections, and GvHD. The present invention relates to novel methods for enhancing the immunosuppressive or the immune stimulatory activities of mesenchymal stem cells (JvfSCs).
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公开(公告)号:US20210190717A1
公开(公告)日:2021-06-24
申请号:US17247838
申请日:2020-12-24
发明人: Yicheng Lu , Pavel I. Reyes , Guangyuan Li , Yifan Wu , Xilin Zhao
IPC分类号: G01N27/27 , H01L29/786 , H01L29/06 , H01L41/113 , H01L41/18 , G01N29/24 , G01N29/04 , G01N27/414
摘要: This document discloses a hybrid and multifunctional biosensing technology consisting of a dual gate thin-film transistor (DGTFT) biosensor with an extended gate covered with magnesium zinc oxide nanostructures (MZOnano) and an MZOnano modified bulk acoustic wave resonator (MZOnano BAW). The technology is used for the full-scale dynamic monitoring of bacterial biofilm formation from its early stage to the maturation stage.
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公开(公告)号:US11043297B2
公开(公告)日:2021-06-22
申请号:US16989625
申请日:2020-08-10
IPC分类号: G06K9/00 , G16H30/40 , A61B5/00 , A61B8/08 , G06T7/00 , G16H30/20 , G16H50/20 , G06K9/32 , G06N3/08
摘要: A device to detect an object in a medical image is described. An image analysis application, executed by the device, receives the medical image as an input. The medical image is next partitioned to sub-regions. Parts of the object are detected in a selection of the sub-regions using a deep-learning neural network (DNN) model. Bounding boxes for the selection are also determined. The bounding boxes are evaluated based on a confidence score detected as above a threshold level. The confidence score designates the parts as contained within the selection. Next, a region of interest (ROI) is determined as a group including the selection. Similar orientations associated with the bounding boxes are comparable to similar orientations of a positive training model of the DNN model. Furthermore, the selection is designated as the ROI within the medical image. The medical image is provided with the ROI to a user.
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