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公开(公告)号:US20250041334A1
公开(公告)日:2025-02-06
申请号:US18718158
申请日:2022-11-28
Applicant: Solventum Intellectual Properties Company
Inventor: Ranjani V. Parthasarathy , Max A. Kruziki , Hannah C. Cohen
Abstract: A method of suppressing microbial virulence. The method includes administering and/or applying a composition. The composition includes (a) a surfactant comprising (i) a polyethylene glycol compound comprising a fatty acid moiety, or (ii) a fatty acid containing compound. The composition further includes (b) (i) a phosphate containing compound, and (ii) a metal salt; and (c) an aqueous carrier. The surfactant is present in an amount of between 0.01 wt. % and 1 wt. %, based on the total weight of the composition.
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公开(公告)号:US12201790B2
公开(公告)日:2025-01-21
申请号:US17432137
申请日:2020-03-06
Applicant: Solventum Intellectual Properties Company
Inventor: Amanda C. Engler , Denise J. Ziemann , Richard L. Jacobson , Kimberly A. Schommer , Elizabeth A. Tatroe , Michael J. Turnbull , Jeffrey D. Cotton , Jener De Oliveira
Abstract: The disclosed tube securement device attaches to the patient's body and to the tube, while allowing for a section of the tube to be detached from the tube securement device. The tube securement device comprises a backing with adhesive coated sections. The backing comprises a first end section, a second end section, and a midsection, separating the first end section from the second end section. The tube securement device further comprises a first adhesive on at least a portion of the first major surface of the first end section, a second adhesive on at least a portion of the first major surface of the second end section, and wherein the first major surface of the midsection is free of tacky adhesive.
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公开(公告)号:US12194113B2
公开(公告)日:2025-01-14
申请号:US16967937
申请日:2019-02-01
Applicant: Solventum Intellectual Properties Company
Inventor: Kai U. Claussen , Silke D. Mechernich , Mareike Richter , Reinhold Hecht , Manfred Ludsteck , Simone Jurjevic
IPC: A61K6/889 , A61C5/00 , A61C7/00 , A61K6/17 , C08F222/10
Abstract: The invention relates to a microcapsule comprising a hollow or porous core, the hollow or porous core being composed of a polymeric material and containing a component of a redox-initiator system, a shell, the shell being composed of a pH-sensitive material. The microcapsule can be used for formulating dental materials.
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公开(公告)号:US20250009479A1
公开(公告)日:2025-01-09
申请号:US18891184
申请日:2024-09-20
Applicant: Solventum Intellectual Properties Company
Inventor: Saswata Chakraborty , Benjamin C. Mac Murray , James D. Hansen , Karl J.L. Geisler , Thomas P. Klun , Daniel J. Skamser , John M. Riedesel , Steven H. Kong , Anja Friedrich
IPC: A61C7/08 , B29C64/135 , B29C64/241 , B29C64/30 , B29C71/02 , B29C71/04 , B29L31/00 , B33Y10/00 , B33Y40/20
Abstract: The present disclosure provides a method of making an orthodontic article. The method includes (a) providing a photopolymerizable composition; (b) selectively curing the photopolymerizable composition using actinic radiation to form an article in the shape of an orthodontic article including a number of layers of at least one photopolymerized polymer; and (c) moving the article and thereby generating a mass inertial force in the uncured photopolymerizable composition. The article has a first surface, and no more than 75% of the first surface has a slope magnitude greater than 2.5 degrees. Orthodontic articles are also provided, including an orthodontic article that is prepared according to the method. Orthodontic articles having low extractable component content are further provided. The mass inertial force tends to form a coating layer of uncured photopolymerizable composition on the article, and curing the coating layer can form a surface having low slope magnitude. The low slope magnitude may be correlated to a low haze of the surface of the article.
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公开(公告)号:US20250005327A1
公开(公告)日:2025-01-02
申请号:US18691766
申请日:2022-09-08
Applicant: Solventum Intellectual Properties Company
Inventor: Yang Liu , Hua Cheng , Russell I. Klopfer , Thomas Schaaf , Matthew R. Gormley
IPC: G06N3/045
Abstract: Systems and techniques are described for configuring and training a neural network including receiving a plurality of documents, providing the received documents to a neural network model comprising a deep convolutional-based encoder including a plurality of squeeze-and-excitation (SE) and residual convolutional modules that form a plurality of SE/residual convolutional block pairs, determining a word embedding matrix for the plurality of documents, providing one or more word embeddings in the word embedding matrix to the encoder, generating one or more label-specific representations based on the output of the plurality of SE/residual convolutional block pairs, computing a probability of a label being present in the one or more documents given the one or more label specific representations and using a first loss function to train the model for frequently occurring labels and a second loss function to train the model for rarely occurring labels.
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公开(公告)号:US20240423755A1
公开(公告)日:2024-12-26
申请号:US18820899
申请日:2024-08-30
Applicant: Solventum Intellectual Properties Company
Inventor: Randilynn B. Christensen , Kenton D. Budd , Afshin Falsafi , Mahmut Aksit , Jana Ninkovic , Jie J. Liu , Mark B. Agre , Masayuki Nakamura , Jason W. Bjork , Bradley D. Craig , Richard P. Rusin , Paul J. Homnick , Joel D. Oxman , Yizhong Wang , Paul R. Klaiber , Bill H. Dodge
Abstract: A method of applying a two-part dental sealant is described comprising providing a syringe device comprising a cartridge including first and second chamber. The first chamber contains a first part of a dental sealant comprising a (meth)acrylate resin and an oxidizing curing agent. The second chamber contains a second part of a dental sealant comprising a (meth)acrylate resin and a reducing curing agent that reacts with the oxidizing curing agent of the first chamber. The first and/or second part of the dental sealant further comprise a single component or multiple components that neutralize acid and promote remineralization. The syringe device comprises a dispensing nozzle comprising a static mixer and an outlet at one end of the cartridge and a plunger at the opposing end of the cartridge. Also described is a kit for storing and applying the dental sealant is described.
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公开(公告)号:US12161530B2
公开(公告)日:2024-12-10
申请号:US18203785
申请日:2023-05-31
Applicant: Solventum Intellectual Properties Company
Inventor: Justin R. Rice , Christopher A. Carroll
Abstract: A wound therapy system includes an instillation fluid canister configured to contain an instillation fluid, a pump fluidly coupled to the instillation fluid canister and operable to deliver the instillation fluid from the instillation fluid canister to a wound, a user interface configured to receive user input indicating one or more geometric attributes of the wound, and a controller electronically coupled to the pump and the user interface. The controller is configured to determine a volume of the wound based on the user input, determine a volume of the instillation fluid to deliver to the wound based on the volume of the wound, and operate the pump to deliver the determined volume of the instillation fluid to the wound.
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公开(公告)号:US12161523B2
公开(公告)日:2024-12-10
申请号:US15734357
申请日:2019-06-05
Applicant: Solventum Intellectual Properties Company
Inventor: Randilynn B. Christensen , Kenton D. Budd , Afshin Falsafi , Mahmut Aksit , Jana Ninkovic , Jie J. Liu , Mark B. Agre , Masayuki Nakamura , Jason W. Bjork , Bradley D. Craig , Richard P. Rusin , Paul J. Homnick , Joel D. Oxman , Yizhong Wang , Paul R. Klaiber
IPC: A61C5/64 , A61C5/68 , A61K6/17 , A61K6/61 , A61K6/62 , A61K6/71 , A61K6/818 , A61K6/851 , A61K6/853 , A61K6/876 , A61K6/887 , C08K9/10 , A61K6/889 , C08L33/10
Abstract: A hardenable (e.g. dental) compositions is described comprising an encapsulated material. The encapsulated material comprises a basic core material and an inorganic shell material having certain viscosity criteria. Also described are dispensing devices and kits are described comprising a hardenable (e.g. dental) composition comprising a liquid material and an encapsulated material wherein the encapsulated material comprises a basic core material and an inorganic shell material comprising a metal oxide surrounding the core. The dispensing devices and kits can facilitate the methods of applying the hardenable composition. The hardenable or hardened (e.g. cured) composition can provide various technical effects such as a delayed release of a basic core material, a delayed increase in basicity, promoting remineralization of a tooth or bone structure, and increasing the average alkaline phosphatase (ALP) activity of pulp cells. In some embodiments, the composition is a dental (e.g. sealant) composition for application to a tooth structure.
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公开(公告)号:US12133766B2
公开(公告)日:2024-11-05
申请号:US17610676
申请日:2020-06-09
Applicant: Solventum Intellectual Properties Company
Inventor: Alexi J. Young , Ronald D. Jesme , Nicholas T. Gabriel
Abstract: An ultrasonic coupling device. The ultrasonic coupling device includes a foam having an aperture; a hydrogel wherein the hydrogel has a water content of at least 10 wt %, wherein at least part of the hydrogel locates in the aperture of the foam; and a near field communication device.
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80.
公开(公告)号:US12112477B2
公开(公告)日:2024-10-08
申请号:US18241538
申请日:2023-09-01
Applicant: Solventum Intellectual Properties Company
Inventor: Brett L. Moore
CPC classification number: G06T7/0012 , A61B5/0013 , A61B5/0077 , A61B5/445 , A61B5/7475 , G06T7/11 , G06T7/12 , G06T7/149 , G16H30/20 , G16H30/40 , G06T2207/20104 , G06T2207/20116 , G06T2207/30088
Abstract: In one example embodiment, a wound imaging system includes a user interface, a computer processor, and an active contouring module. The user interface is configured to display an image of a wound acquired by the wound imaging system and selectively receive inputs from a user defining an initial perimeter of the wound. An active contouring module is configured to operate on the computer processor to receive the inputs defining the initial perimeter of the wound, identify features of the image on opposing sides of the initial perimeter of the wound, and identify an actual perimeter of the wound based on the initial perimeter of the wound and the identified features. The user interface is further configured to display, on the image of the wound, the actual perimeter of the wound as identified by the active contouring module and selectively receive inputs from the user to modify the actual perimeter of the wound.
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