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公开(公告)号：US5330426A
公开(公告)日：1994-07-19
申请号：US930749
申请日：1992-08-13
CPC分类号： A61M5/2429 , A61M5/2448 , A61M2005/3104 , A61M5/348
摘要： A device for intermixing a first component, such as a parenteral fluid with a second component, such as an immobilized drug carried by a scaffold to form a beneficial agent which, following the mixing step, can be dispensed directly from the device for infusion into a patient. The device includes novel mechanisms for mateably interconnecting a container, such as a glass vial containing the first component with a housing having a fluid outlet which houses a sealed container containing the second component, and then for controllably mixing the components under sterile conditions to form an injectable solution which is automatically dispensed through the fluid outlet of the device.
摘要翻译： 用于将第一组分（例如肠胃外流体）与第二组分（例如由支架携带的固定化药物）混合以形成有益剂的装置，其可以在混合步骤之后直接从用于输注的装置中分配 患者。 该装置包括用于将容器（例如包含第一部件的玻璃小瓶）与具有流体出口的壳体可互换地互连的新颖机构，该壳体容纳包含第二组分的密封容器，然后在无菌条件下可控地混合组分以形成 注射溶液，其通过装置的流体出口自动分配。
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公开(公告)号：US5267957A
公开(公告)日：1993-12-07
申请号：US870553
申请日：1992-04-17
CPC分类号： A61M5/1409 , A61M5/152 , Y10S128/12
摘要： An apparatus for controllably intermixing two or more components in a sterile, closed environment to produce a flowable substance and then for expelling the flowable substance from the apparatus at a precisely controlled rate. The apparatus is particularly useful for medical applications and includes a dispenser portion with its own stored energy element provided in the form of an elastomeric membrane and a coupling mechanism for coupling a drug vial to the dispenser portion for controlled mixing a medicament contained within the drug vial with a diluent stored within the dispenser portion of the apparatus via a sterile pathway.
摘要翻译： 一种用于在无菌，封闭环境中可控地混合两种或多种组分的装置，以产生可流动物质，然后以精确控制的速率从装置中排出可流动物质。 该装置对于医疗应用特别有用，并且包括具有以弹性体膜形式提供的其自身存储的能量元件的分配器部分和用于将药物小瓶耦合到分配器部分的联接机构，用于控制混合药物瓶内包含的药物 其中稀释剂通过无菌途径储存在装置的分配器部分内。
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公开(公告)号：US4240161A
公开(公告)日：1980-12-23
申请号：US13375
申请日：1979-02-21
CPC分类号： A61F2/2406 , Y10T137/7903
摘要： A free floating pivoting disc heart valve in which the disc has a generally arcuate segment configuration positioned so as to present a generally convex surface toward the outflow side of said base and a generally concave surface toward the inflow side of the base when viewed in the closed configuration.
摘要翻译： 一种自由浮动的枢转心脏瓣膜，其中盘具有大致弓形的段构造，其定位成当在闭合状态下观察时呈现朝向所述基部的流出侧的大致凸形表面和朝向底部的流入侧的大致凹入表面 组态。
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公开(公告)号：US08133204B1
公开(公告)日：2012-03-13
申请号：US12925072
申请日：2010-10-12
申请人： Marshall S. Kriesel
发明人： Marshall S. Kriesel
IPC分类号： A61M5/00
CPC分类号： A61M5/1454 , A61M5/1413 , A61M5/148 , A61M5/16881
摘要： A dispensing device for dispensing medicaments to a patient comprising a plurality of threadably interconnectable sub-assemblies. One of these sub-assemblies houses a novel collapsible fluid reservoir defining component that is carried by a carriage while another comprises a fluid delivery and control assembly that includes a novel flow control means that functions to control the flow of medicinal fluid from the fluid reservoir of the collapsible reservoir defining component toward the patient via a plurality of fluid flow control passageways. In one form of the invention the collapsible fluid reservoir is filled at time of manufacture. In another form of the invention the collapsible fluid reservoir can be filled in the field using a syringe assembly.
摘要翻译： 一种用于向患者分配药物的分配装置，包括多个可螺纹连接的子组件。 这些子组件之一容纳有由滑架承载的新颖的可折叠流体储存器限定部件，而另一个包括流体输送和控制组件，其包括新颖的流量控制装置，其用于控制来自流体储存器的药液流动 可折叠储存器通过多个流体流动控制通道限定朝向患者的部件。 在本发明的一种形式中，可压缩流体储存器在制造时被填充。 在本发明的另一种形式中，可以使用注射器组件将可收缩的流体储存器填充在现场中。
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公开(公告)号：US08083717B2
公开(公告)日：2011-12-27
申请号：US12316972
申请日：2008-12-17
申请人： Marshall S. Kriesel
发明人： Marshall S. Kriesel
IPC分类号： A61M5/20
CPC分类号： A61M5/1413 , A61M5/1408 , A61M5/14244 , A61M5/1454 , A61M5/16881 , A61M39/18 , A61M2205/583
摘要： A dispensing device for dispensing medicaments to a patient that includes first, second and third stand-alone, inter-connectable assemblies. The first of these assemblies comprises a fluid delivery and control assembly that includes a novel flow control assembly that functions to control the flow of medicinal fluid from the fluid reservoirs of the first and second assemblies of the invention toward the patient via a plurality of fluid flow control passageways. The second and third stand-alone reservoir defining components, which are interconnected with the fluid and delivery control component, each include an integrally formed, hermetically sealed collapsible container and a spring for controllably collapsing the container.
摘要翻译： 一种用于向患者分配药物的分配装置，包括第一，第二和第三独立的可相互连接的组件。 这些组件中的第一个包括流体输送和控制组件，其包括新颖的流量控制组件，其用于控制药液从本发明的第一和第二组件的流体储存器经由多个流体流向患者的流动 控制通道。 与流体和输送控制部件互连的第二和第三独立储存器限定部件各自包括一体形成的气密密封的可折叠容器和用于可控地塌缩容器的弹簧。
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公开(公告)号：US20100056997A1
公开(公告)日：2010-03-04
申请号：US12316972
申请日：2008-12-17
申请人： Marshall S. Kriesel
发明人： Marshall S. Kriesel
IPC分类号： A61M5/31
CPC分类号： A61M5/1413 , A61M5/1408 , A61M5/14244 , A61M5/1454 , A61M5/16881 , A61M39/18 , A61M2205/583
摘要： A dispensing device for dispensing medicaments to a patient that includes first, second and third stand-alone, inter-connectable assemblies. The first of these assemblies comprises a fluid delivery and control assembly that includes a novel flow control assembly that functions to control the flow of medicinal fluid from the fluid reservoirs of the first and second assemblies of the invention toward the patient via a plurality of fluid flow control passageways. The second and third stand-alone reservoir defining components, which are interconnected with the fluid and delivery control component, each include an integrally formed, hermetically sealed collapsible container and a spring for controllably collapsing the container.
摘要翻译： 一种用于向患者分配药物的分配装置，包括第一，第二和第三独立的可相互连接的组件。 这些组件中的第一个包括流体输送和控制组件，其包括新颖的流量控制组件，其用于控制药液从本发明的第一和第二组件的流体储存器经由多个流体流向患者的流动 控制通道。 与流体和输送控制部件互连的第二和第三独立储存器限定部件各自包括一体形成的气密密封的可折叠容器和用于可控地塌缩容器的弹簧。
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公开(公告)号：US06527744B1
公开(公告)日：2003-03-04
申请号：US09607519
申请日：2000-06-28
IPC分类号： A61M3700
CPC分类号： A61M5/14276 , A61M5/14248 , A61M5/145 , A61M5/1452 , A61M5/14586 , A61M2205/36
摘要： A fluid delivery apparatus for infusing medicinal fluids into a patient which is of a compact, low profile, laminate construction. The apparatus embodies a novel light activated expanding polymer material which uniquely functions as an internal energy source for expelling the medicinal fluids from the device. The light polymer mass is activated by a novel light source in a manner to controllably expel fluid from the device. Further, the light actuated polymer can be specifically tailored to provide precise, predictable protocol delivery of the medicinal agent stored within the reservoir of the device. In one form of the invention, the fluid delivery apparatus is implantable within the patient's body.
摘要翻译： 一种用于将药液注入患者体内的流体输送装置，该流体输送装置具有紧凑的薄型叠层结构。 该装置体现了一种新颖的光活化膨胀聚合物材料，其独特地用作用于从设备排出药液的内部能源。 轻质聚合物质量以可控制地排出流体的方式由新型光源激活。 此外，光致聚合物可以被特别地定制以提供存储在装置的储存器内的药剂的精确的，可预测的方案递送。 在本发明的一种形式中，流体输送装置可植入患者体内。
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公开(公告)号：US06293159B1
公开(公告)日：2001-09-25
申请号：US09488961
申请日：2000-01-21
IPC分类号： G01F138
CPC分类号： A61M5/16854 , A61M5/152 , A61M5/16886 , A61M2205/583 , A61M2209/045 , G01P1/07 , G01P13/0026 , G01P13/0066
摘要： An apparatus for delivering fluids at a precisely controlled rate which includes a fluid dispensing component having a fluid reservoir for containing the fluids to be delivered and a reservoir fill component which can be removably interconnected with the fluid dispensing component. The reservoir fill assembly is uniquely designed to accept a vial component of conventional construction which is factory filled with the medicinal fluid to be delivered to the patient. The dispenser component embodies a highly novel fluid flow indicator that provides a readily discernible visual indication of fluid flow status through the device.
摘要翻译： 一种用于以精确控制的速率输送流体的装置，其包括具有用于容纳待输送流体的流体储存器的流体分配部件和可与流体分配部件可拆卸地互连的储存器填充部件。 储存器填充组件被独特地设计成接受常规结构的小瓶部件，该小瓶部件在工厂中填充有要输送给患者的药液。 分配器部件体现了高度新颖的流体流量指示器，其提供通过装置的流体流动状态的容易辨别的视觉指示。
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公开(公告)号：US06245042B1
公开(公告)日：2001-06-12
申请号：US09390219
申请日：1999-09-03
IPC分类号： A61M3700
CPC分类号： A61M5/14276 , A61K9/0004 , A61K9/0068 , A61M5/14586 , A61M31/002 , A61M2205/3613 , A61M2250/00
摘要： A delivery device for the administration of nutrients, drugs, vitamins, trace elements and the like to a ruminant. The device embodies a thermal expanding polymer material which, when heated by the animal's body heat functions as an internal energy source for controllably expelling the beneficial agents from the device over extended period of time of up to 200 days. The device is of a size and shape that can be introduced into the ruminant via the esophagus and is of a density such that the device will be retained within the reticulo-rumen of the animal for the effective controlled release of the beneficial agents to the animal.
摘要翻译： 用于向反刍动物施用营养素，药物，维生素，微量元素等的递送装置。 该装置体现了一种热膨胀聚合物材料，当被动物的身体加热时，热量作为内部能量源起作用，用于在长达200天的延长时间内可控地将有益试剂从装置中排出。 该装置具有可以通过食道引入反刍动物的尺寸和形状，并且具有密度，使得该装置将被保留在动物的网状瘤胃内，以有效地将有益的药剂释放到动物中 。
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公开(公告)号：US06245041B1
公开(公告)日：2001-06-12
申请号：US09561786
申请日：2000-05-01
申请人： Marshall S. Kriesel
发明人： Marshall S. Kriesel
IPC分类号： A61M3700
CPC分类号： A61M5/152 , A61M5/1407 , A61M5/1409 , A61M5/141 , A61M5/16827 , A61M2209/045
摘要： An elastomeric bladder stored energy type infusion apparatus that can be filled with a medicinal fluid and, after being filled, can efficiently deliver the medicinal fluid to the patient at a selected rate. The apparatus includes a delivery component for delivering medicinal fluid to the patient and a fill component that can expeditiously be used to fill the fluid reservoir of the delivery component in the field.
摘要翻译： 一种弹性囊状储能型输液装置，其可以填充药液，并且在填充之后可以以选定的速率有效地将药液输送到患者。 该装置包括用于将药液输送给患者的输送部件和可以迅速用于填充现场输送部件的流体储存器的填充部件。
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