利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

78 条记录 (耗时 0.016 秒)

    Self-assembling modular percutaneous valve and methods of folding, assembly and delivery
    1.
    发明授权
    Self-assembling modular percutaneous valve and methods of folding, assembly and delivery 有权
    自组装模块化经皮瓣膜和折叠，装配和输送方法

    公开(公告)号：US09504562B2

    公开(公告)日：2016-11-29

    申请号：US12686338

    申请日：2010-01-12

    申请人： Yoram Richter ,  Jacob Richter ,  Ety Weisz

    发明人： Yoram Richter ,  Jacob Richter ,  Ety Weisz

    IPC分类号： A61F2/24 ,  A61F2/844

    CPC分类号： A61F2/2415 ,  A61F2/24 ,  A61F2/2406 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/844 ,  A61F2210/0014 ,  A61F2230/0091 ,  A61F2250/006

    摘要： The present invention provides a modular prosthetic valve device having two or more device modules for percutaneous delivery unassembled at or near the valve implantation site and assembly at least in part using a self-assembly member, and a system and method of folding, delivering and assembling the device. The device modules may include a support structure and a valve module. The valve module has an unassembled, folded delivery configuration, and an unfolded, assembled (via the self-assembly member) working configuration. The valve module may be a single-piece leaflets substructure or a plurality of valve sections. The self-assembly member has a delivery configuration and may be reverted to a preset configuration for valve module assembly. The unassembled valve module may be rolled along its circumferential axis towards its height to a folded diameter equivalent to one rolled leaflet, providing a percutaneous valve device having a smaller delivery diameter than pre-assembled valve devices.

    摘要翻译： 本发明提供了一种具有两个或更多个装置模块的模块化假体瓣膜装置，所述装置模块用于至少部分地使用自组装构件而在阀注入部位处或附近经组织的经皮递送，以及折叠，输送和组装的系统和方法 装置。 装置模块可以包括支撑结构和阀模块。 阀模块具有未组装的折叠输送构造，以及展开的，通过自组装构件组装（通过自组装构件）的工作构型。 阀模块可以是单件式叶片子结构或多个阀部分。 自组装构件具有输送构造并且可以被还原成用于阀模块组装的预设构型。 未组装的阀组件可以沿着其圆周轴线向其高度滚动至相当于一个滚动小叶的折叠直径，从而提供具有比预组装的阀装置更小的输送直径的经皮瓣装置。

    Electromagnetically controlled heart valve
    4.
    发明授权
    Electromagnetically controlled heart valve 失效
    电磁控制心脏瓣膜

    公开(公告)号：US5135538A

    公开(公告)日：1992-08-04

    申请号：US709782

    申请日：1991-06-03

    申请人： Andrzej M. Pawlak ,  David B. Young

    发明人： Andrzej M. Pawlak ,  David B. Young

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2409 ,  A61F2/2406 ,  Y10T137/7838 ,  Y10T137/7898

    摘要： A unidirectional flow heart valve includes a passageway having an inlet side and an outlet side. A disk occluder is disposed within the passageway. The disk occluder has a closed position wherein the disk occluder occludes fluid flow through the passageway and an open position wherein the disk occluder permits fluid flow through the passageway. A fulcrum causes the disk occluder to pivot off center between the open and closed positions. An electromagnetic control mechanism forces the disk occluder to remain closed when energized until a predetermined net pressure is reached against the disk occluder. When the electromagnetic control mechanism is either selectively deenergized or the force on the occluder disk is greater than the holding force of the electromagnetic control mechanism, the disk occluder is released from the closed position to pivot on the fulcrum in response to fluid pressure.

    摘要翻译： 单向流心脏瓣膜包括具有入口侧和出口侧的通道。 盘片封堵器设置在通道内。 盘封闭器具有闭合位置，其中盘封闭器封闭通过通道的流体流动，以及打开位置，其中盘封闭器允许流体流过通道。 支点导致盘闭塞器在打开位置和关闭位置之间从中心枢转。 当通电时，电磁控制机构迫使盘封闭器保持关闭，直到达到预定的净压力而抵靠盘封闭器。 当电磁控制机构被选择性地断电或阻塞盘上的力大于电磁控制机构的保持力时，盘封闭器从关闭位置释放，以响应于流体压力在支点上枢转。

    Artificial heart valve for implantation in a blood vessel
    5.
    发明授权
    Artificial heart valve for implantation in a blood vessel 失效
    用于植入血管的人造心脏瓣膜

    公开(公告)号：US4994077A

    公开(公告)日：1991-02-19

    申请号：US342225

    申请日：1989-04-21

    申请人： Richard L. Dobben

    发明人： Richard L. Dobben

    IPC分类号： A61F2/24 ,  A61F2/86

    CPC分类号： A61F2/2475 ,  A61F2/2406 ,  A61F2/86 ,  Y10T137/7875 ,  Y10T137/7898

    摘要： An artificial heart valve is designed to fit into a blood vessel when a patient is too weak to undergo open heart surgery. The valve has a disk shaped flap valve threaded on a bent wire which may be anchored in a blood vessel. One embodiment uses a clip anchor which is bent into somewhat the shape of a safety pin. Another embodiment uses a STENT as the anchor. The wire snags on the wall of the blood vessel in order to keep the valve from migrating through the blood vessel. The flap valve opens and closes under the pressure of blood which is ebbing and flowing responsive to a pumping heart.

    摘要翻译： 人造心脏瓣膜被设计成当患者太弱而无法进行心脏直视手术时可以装入血管。 该阀具有螺纹在可以锚定在血管中的弯曲线上的盘形瓣阀。 一个实施例使用弯曲成一定程度上安全销的形状的夹子锚。 另一个实施例使用STENT作为锚。 电线阻塞在血管的壁上，以保持瓣膜不通过血管迁移。 瓣阀在血液压力下打开和关闭，血液响应于泵送心脏而缓慢流动。

    Heart valve prosthesis
    6.
    发明授权
    Heart valve prosthesis 失效
    心脏瓣膜假体

    公开(公告)号：US4713071A

    公开(公告)日：1987-12-15

    申请号：US906623

    申请日：1986-09-10

    申请人： Naum A. Iofis ,  Rudolf N. Vettsel ,  Alexandr S. Bukatov ,  Semen G. Khurtsilava

    发明人： Naum A. Iofis ,  Rudolf N. Vettsel ,  Alexandr S. Bukatov ,  Semen G. Khurtsilava

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2406

    摘要： A heart valve prosthesis comprises a valve ring having an opening for the flow of blood, a valve poppet floatingly mounted during opening and closing. For floatingly containing the poppet, and there is provided a single upper support and a lower support structure. The upper support has a flat portion supporting the poppet that bears thereagainst with a depression made in the top side of the poppet. The lower support structure has tabs for supporting the poppet so that the poppet is in the surface-to-the surface contact with the upper support and tabs of the lower support structure when the poppet is in the open position.

    摘要翻译： 心脏瓣膜假体包括具有用于血液流动的开口的阀环，在打开和关闭期间浮动地安装的阀提升阀。 用于浮动地包含提升阀，并且提供单个上部支撑件和下部支撑结构。 上支撑件具有支撑提升阀的平坦部分，该提升阀带有在提升阀顶部形成的凹部。 下支撑结构具有用于支撑提升阀的突出部，使得当提升阀处于打开位置时，提升阀在表面与表面与下支撑结构的上支撑件和突片接触。

    Heart valve prosthesis
    7.
    发明授权
    Heart valve prosthesis 失效
    心脏瓣膜假体

    公开(公告)号：US4423525A

    公开(公告)日：1984-01-03

    申请号：US313843

    申请日：1981-10-22

    申请人： Franco Vallana ,  Gioachino Bona

    发明人： Franco Vallana ,  Gioachino Bona

    IPC分类号： A61F2/24 ,  A61F1/22

    CPC分类号： A61F2/2409 ,  A61F2/2406 ,  Y10T137/7898 ,  Y10T137/7903

    摘要： The prosthesis comprises an annular frame and a disc-shaped obturator which is coupled to the frame and is pivotable, under the action of the blood flow, between an open annular position and a closed angular position, so as to allow the flow of blood through the aperture of the annular frame in one direction and the interruption of the flow in the opposite direction, respectively. The obturator is coupled to the frame in such a way that, in the open position, it may orient itself in a direction substantially perpendicular to the plane of the frame. The side of the obturator which faces away from the central axis of the annular frame in the open angular position is defined, at least in its peripheral part, by a surface which is generated by the rotation, about the central axis of the obturator, of a curve the locus of the centers of curvature of which lies on the opposite side of this curve from a curve which generates, by rotation around the central axis, a surface defining the other side of the obturator.

    摘要翻译： 假体包括环形框架和盘形闭塞器，其联接到框架并且在血流的作用下可枢转在开放的环形位置和闭合的角位置之间，以允许血液流过 环形框架在一个方向上的孔径和分别在相反方向上的流动中断。 闭塞器以这样的方式联接到框架，使得在打开位置，其可以在基本上垂直于框架的平面的方向上定向自身。 至少在其周边部分中，封闭器的面向远离环形框架的中心轴线的侧面，该表面由围绕闭塞器的中心轴线的旋转产生的表面 其曲率中心的轨迹位于该曲线的与该中心轴线周围旋转的曲线相反侧的轨迹，该曲线限定了闭塞器另一侧的表面。

    Electro-chemically machined ring and strut structure for prosthetic heart valves
    8.
    发明授权
    Electro-chemically machined ring and strut structure for prosthetic heart valves 失效
    人造心脏瓣膜的电化学加工环和支柱结构

    公开(公告)号：US4276132A

    公开(公告)日：1981-06-30

    申请号：US18566

    申请日：1979-03-08

    申请人： Bruce E. Fettel ,  Paul E. Morris ,  Leo J. Lichte

    发明人： Bruce E. Fettel ,  Paul E. Morris ,  Leo J. Lichte

    IPC分类号： A61F2/24 ,  B23H9/00 ,  B23P1/00 ,  A61F1/22

    CPC分类号： A61F2/2406 ,  B23H9/00

    摘要： This invention relates to the electrochemical machining of integrally formed prosthetic heart valve structures in which both the structural integrity of the valve and the blood flow through the valve is improved as a result of the integral formation of the valve structure. In particular, such heart valves comprise a ring and a pendant structure, such as a strut, for supporting the opening and closing of a discoid valve occluder. Integral formation of the strut with the ring permits the cross-sectional shape of the strut to be machined without overheating and distortion to conform to a teardrop shape having favorable fluid-dynamic characteristics thereby improving the flow of blood through the valve across the strut. The integral formation of the strut with the ring further results in the elimination of the weld fillet between the strut and the ring, thereby permitting the height of the ring to be reduced, which further improves the fluid dynamic characteristics of the valve. The overall structural integrity of the heart valve structure is also improved by the shape of the strut which permits the increase in the total cross-sectional area of the strut while retaining the favorable fluid flow characteristics of the valve. Thus, this invention provides for improved structural integrity of the valve and at the same time, improved flow characteristics through the valve.

    摘要翻译： 本发明涉及整体形成的假体心脏瓣膜结构的电化学加工，其中由于阀结构的整体形成，瓣膜的结构完整性和通过瓣膜的血液流动都得到改善。 特别地，这种心脏瓣膜包括环和悬挂结构，例如支柱，用于支撑盘状瓣膜闭塞器的打开和关闭。 支柱与环的整体形成允许加工支柱的横截面形状而不会过热和变形，以符合具有有利的流体动力特性的泪滴形状，从而改善穿过支柱的阀通过阀的流动。 支柱与环的整体形成进一步导致消除支柱和环之间的焊缝，从而允许减小环的高度，这进一步改善了阀的流体动力特性。 通过支柱的形状也可以改善心脏瓣膜结构的整体结构完整性，这样可以在保持阀的有利的流体流动特性的同时增加支柱的总横截面面积。 因此，本发明提供了改进的阀的结构完整性，同时提高了通过阀的流动特性。

    Metallic cardiac valve prosthesis
    10.
    发明授权
    Metallic cardiac valve prosthesis 失效
    金属心脏瓣膜假体

    公开(公告)号：US4225980A

    公开(公告)日：1980-10-07

    申请号：US964442

    申请日：1978-11-28

    申请人： Wilson Ramos Martinez

    发明人： Wilson Ramos Martinez

    IPC分类号： A61F2/24 ,  A61F1/22

    CPC分类号： A61F2/2406 ,  Y10T137/7903

    摘要： A metallic cardiac valve prosthesis having an aortic as well as a mitral application, the purpose of which is to obtain an ample, highly physiological and laminar flow of blood, includes a ring, the outer contour of which is circular and the inner contour of which is oval. The interior of the ring is provided with a lenticular plug acting in the same way as the plug of a butterfly valve.

    摘要翻译： 具有主动脉和二尖瓣应用的金属心脏瓣膜假体，其目的是获得充足的高度生理和层流的血液，其包括环，其外轮廓为圆形，其外轮廓为 是椭圆形 环的内部设置有以与蝶阀的塞子相同的方式起作用的透镜塞。