公开(公告)号：US20240366210A1

公开(公告)日：2024-11-07

申请号：US18777323

申请日：2024-07-18

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： John Richard Carpenter ,  Louis A. Campbell

IPC: A61B17/04 ,  A61B17/06

Abstract: A tissue anchor includes a memory metal wire configured to transition between an at least partially straightened delivery configuration and an expanded deployed configuration forming an anchor and a suture-attachment feature configured to have a suture coupled thereto. In the expanded deployed configuration, one or more portions of the memory metal wire extend radially outward from a center of the tissue anchor.

公开(公告)号：US12064346B2

公开(公告)日：2024-08-20

申请号：US17811545

申请日：2022-07-08

Applicant: Edwards Lifesciences Corporation

Inventor： Bin Tian ,  Rodolfo Rodriguez ,  Louis A. Campbell ,  Steven M. Claessens ,  Carolyn Sue Martinez

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2433 ,  A61F2/2445 ,  A61F2210/0085 ,  A61F2220/0008 ,  A61F2220/0075 ,  A61F2240/001 ,  A61F2250/0001 ,  A61F2250/0069

Abstract: Systems, devices, kits, and methods are described for securing a bioprosthetic heart valve within an anatomical feature of a patient. Kits can comprise a bioprosthetic heart valve, a curable composition, and an applicator configured to deliver the curable composition to a target area. The bioprosthetic heart valve can comprise a support structure and one or more valve leaflets coupled thereto. The support structure can comprise a sewing portion peripheral of the bioprosthetic heart valve. The support structure and the valve leaflets can define a central flow orifice. The curable composition can comprise a pre-polymer composition and an initiator. Methods can comprise positioning the bioprosthetic heart valve within the anatomical feature of a patient, applying the curable composition to one or both of the bioprosthetic heart valve and the anatomical feature, and curing the curable composition for a cure time. The applying can be performed before or after the positioning.

公开(公告)号：US20230397987A1

公开(公告)日：2023-12-14

申请号：US18452545

申请日：2023-08-20

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Louis A. Campbell ,  Andrew Phung

IPC: A61F2/24 ,  A61F2/00

CPC classification number: A61F2/2427 ,  A61F2/0095 ,  A61F2/2412

Abstract: An improved holder and storage system for prosthetic heart valves that pre-shields or pre-constricts the commissure posts of the valve to prevent suture looping. Pre-shielding and pre-constriction mean at the time of manufacture, so that the valves are stored with the commissure posts shielded and/or constricted. The holders may have solid legs that directly contact and constrict and hold the commissure posts without the use of sutures in tension that might creep over the time in storage. The holder may have a base in contact with the inflow end and a shaft portion that projects through the valve leaflets and cooperates with movable legs on the outflow end of the valve in contact with the commissure posts. The holders may, alternatively, have flexible leg members that extend through the valve and have distal end portions configured to extend over and shield the tips of commissure posts.

公开(公告)号：US11730592B2

公开(公告)日：2023-08-22

申请号：US16818992

申请日：2020-03-13

Applicant: Edwards Lifesciences Corporation

Inventor： Louis A. Campbell ,  Andrew Phung

IPC: A61F2/24 ,  A61F2/00

CPC classification number: A61F2/2427 ,  A61F2/0095 ,  A61F2/2412

Abstract: An improved holder and storage system for prosthetic heart valves that pre-shields or pre-constricts the commissure posts of the valve to prevent suture looping. Pre-shielding and pre-constriction mean at the time of manufacture, so that the valves are stored with the commissure posts shielded and/or constricted. The holders may have solid legs that directly contact and constrict and hold the commissure posts without the use of sutures in tension that might creep over the time in storage. The holder may have a base in contact with the inflow end and a shaft portion that projects through the valve leaflets and cooperates with movable legs on the outflow end of the valve in contact with the commissure posts. The holders may, alternatively, have flexible leg members that extend through the valve and have distal end portions configured to extend over and shield the tips of commissure posts.

公开(公告)号：US11690709B2

公开(公告)日：2023-07-04

申请号：US16908623

申请日：2020-06-22

Applicant: Edwards Lifesciences Corporation

Inventor： Louis A. Campbell

IPC: A61F2/24

CPC classification number: A61F2/2409 ,  A61F2/2418 ,  A61F2/2448 ,  A61F2/2412 ,  A61F2/2433 ,  A61F2210/0014 ,  A61F2220/0025 ,  A61F2230/0054 ,  A61F2250/006 ,  A61F2250/0063 ,  A61F2250/0096

Abstract: A spacer for creating a docking station for a transcatheter heart valve is provided. The spacer changes an effective diameter and/or a shape of an implanted bioprosthetic structure such as a bioprosthetic heart valve or annuloplasty ring, providing a supporting structure into which the transcatheter valve expands without over expanding. The spacer may be deployed through an interventional technique either through transseptal access, transfemoral access, or transapical access and is typically deployed at least in part on an inflow portion of the implanted bioprosthetic structure.

公开(公告)号：US20230125047A1

公开(公告)日：2023-04-20

申请号：US18069082

申请日：2022-12-20

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin ,  Louis A. Campbell ,  Salvador Marquez ,  James R. Yamada ,  Rodolfo Rodriguez ,  Da-Yu Chang ,  Steven M. Ford

IPC: A61F2/24

Abstract: A minimally-invasive annuloplasty ring for implant at a mitral annulus. The annuloplasty ring has an inner core member with a C-shaped plan view that generally defines an oval with a major axis and a minor axis, and is symmetric about the minor axis. A posterior portion of the core member bisected by the minor axis has a thicker radial dimension than a pair of free end regions terminating on an anterior side of the core member. The radial thickness smoothly transitions between the posterior portion and the end regions. The inner core member may be covered with a fabric, and is a superelastic metal so that it can be straightened out and delivered through an access tube. The curvatures and thicknesses around the core member are selected so that the strain experienced when straightened does not exceed 7-8%.

公开(公告)号：US11517428B2

公开(公告)日：2022-12-06

申请号：US16666319

申请日：2019-10-28

Applicant: Edwards Lifesciences Corporation

Inventor： Hao Shang ,  Louis A. Campbell

IPC: A61F2/24 ,  A61L27/36 ,  A61L27/54 ,  A61L31/04 ,  A61L31/14 ,  A61F2/00

Abstract: Artificial heart valves, their manufacture, and methods of use are described. Generally, artificial heart valves can be deployed to replace or supplement defective heart valves in a patient. These artificial heart valves can comprise a frame with an inner skirt and leaflets. These inner skirt and leaflets can be generated from regenerative tissue to allow integration of the tissue with the body of a patient, while the frame can be generated from bioabsorbable material to allow dissolution of the frame over time. This combination of materials may allow for the artificial valve to grow with a patient and avoid costly and potentially dangerous replacement for patients receiving artificial valves.

公开(公告)号：US20220370200A1

公开(公告)日：2022-11-24

申请号：US17817231

申请日：2022-08-03

Applicant: Edwards Lifesciences Corporation

Inventor： Rodolfo Rodriguez ,  Brian S. Conklin ,  Louis A. Campbell

IPC: A61F2/24

Abstract: An annuloplasty band having a differentiation in area moment of inertia, where the area moment of inertia in the out of plane direction is much less than the area moment of inertia in the plane of the annulus. This makes the band stiff enough to hold the annulus in the correct shape while being flexible enough out of plane to minimize the risk of suture dehiscence or breakage. One example is a C-shaped band with a core formed of nitinol and having a constant cross-section with a wider radial dimension than an axial dimension. The cross-section may be rectangular. The band is asymmetric across a minor axis with one end extending around the anterior side farther than the other. The free ends rise up from adjacent lateral sides, and a continuous posterior mid-section also rises upward.

公开(公告)号：US11311378B2

公开(公告)日：2022-04-26

申请号：US16908375

申请日：2020-06-22

Applicant: Edwards Lifesciences Corporation

Inventor： Frederic B. Hodshon ,  Rafael Pintor ,  August R. Yambao ,  Abhishek Gautam ,  Louis A. Campbell ,  Lawrence J. Farhat ,  Tammy Huntley ,  Faisal Kalam ,  Travis Zenyo Oba ,  Qinggang Zeng

IPC: A61F2/24 ,  A61F2/00

Abstract: Packaging for prosthetic heart valves including an assembly for securely retaining a heart valve within a jar and facilitating retrieval therefrom. The assembly includes a packaging sleeve that fits closely within the jar and has a clip structure for securing a valve holder. Contrary to previous designs, in one embodiment the valve holder is directed downward into the jar, and the valve is retained with an inflow end upward. The valve may have flexible leaflets, and a leaflet parting member on the end of the shaft extends through the leaflets and couples with the valve holder. The assembly of the packaging sleeve, valve, and holder can then be removed from the jar and a valve delivery tube connected with the holder, or to the leaflet parting member. The packaging sleeve may be bifurcated into two halves connected at a living hinge to facilitate removal from around the valve/holder subassembly.

公开(公告)号：US20210353408A1

公开(公告)日：2021-11-18

申请号：US17389771

申请日：2021-07-30

Applicant: Edwards Lifesciences Corporation

Inventor： Harvey H. Chen ,  Son V. Nguyen ,  Devin D. Nguyen ,  Diana Marie George ,  August R. Yambao ,  Jyoti B. Rao ,  Alyssa E. Kornswiet ,  Lisong Ai ,  Stephen W. Tang ,  Edward Romero ,  Kevin K. Dang ,  Meena Francis ,  Louis A. Campbell ,  Grace Myong Kim

IPC: A61F2/24

Abstract: A hybrid heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The hybrid heart valve includes a substantially non-expandable, non-compressible prosthetic valve member having a peripheral sealing ring and an expandable stent frame projecting from an inflow end, thereby enabling attachment to the annulus without sutures. The stent frame may be plastically-expandable and may have a thin fabric layer covering its entirety as well as secondary sealing structures around its periphery to prevent paravalvular leaking. Other sealing solutions include interactive steps at the time of valve implant to establish seals around the stent and especially between the stent and the sealing ring of the valve member.