公开(公告)号：US20240325150A1

公开(公告)日：2024-10-03

申请号：US18743896

申请日：2024-06-14

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Brian S. Conklin ,  Louis A. Campbell ,  Derrick Johnson

IPC: A61F2/24

CPC classification number: A61F2/2496 ,  A61F2/2412 ,  A61F2/2427 ,  A61F2/2445 ,  A61F2/2466

Abstract: An articulating implant holder system for heart valve repair or replacement has an implant configured to be secured to a heart valve annulus, an implant holder secured to the implant, an articulating handle assembly comprising a handle, a swivel pivotably secured to the handle at a first location and a connector pivotably secured to the swivel at a second location, an actuating cable secured between the handle and the connector to cause the swivel to move from a first position to a second position, and a latch removably secured to the implant holder. A plurality of sizer heads are configured to correspond to different sizes of heart valve annuluses and each of the plurality of sizer heads has a latching feature. A latching feature of the swivel is configured to removably snap on to the latching feature of each of the plurality of sizer heads and is configured to permanently snap on to the latch.

公开(公告)号：US11883282B2

公开(公告)日：2024-01-30

申请号：US16695008

申请日：2019-11-25

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Visith Chung ,  Da-Yu Chang ,  Brian S. Conklin ,  Grace Myong Kim ,  Louis A. Campbell ,  Donald E. Bobo, Jr. ,  Myron Howanec, Jr. ,  David S. Lin ,  Peng Norasing ,  Francis M. Tran ,  Mark Van Nest ,  Thomas Chien ,  Harvey H. Chen ,  Isidro L. Guerrero ,  Derrick Johnson ,  Paul A. Schmidt ,  Cindy Woo

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2/2445 ,  A61F2/2433 ,  A61F2210/0004 ,  A61F2210/0014 ,  A61F2220/0033 ,  A61F2220/0075 ,  A61F2250/001 ,  A61F2250/0004 ,  A61F2250/006 ,  A61F2250/0063 ,  A61F2250/0071 ,  A61F2310/00011

Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander.

公开(公告)号：US20230147439A1

公开(公告)日：2023-05-11

申请号：US18061388

申请日：2022-12-02

Applicant: Edwards Lifesciences Corporation

Inventor： Hao Shang ,  Louis A. Campbell

IPC: A61F2/24 ,  A61L27/36 ,  A61L27/54 ,  A61L31/04 ,  A61L31/14

CPC classification number: A61F2/2418 ,  A61F2/2433 ,  A61F2/2436 ,  A61L27/3633 ,  A61L27/54 ,  A61L31/041 ,  A61L31/148 ,  A61F2002/0081

Abstract: Artificial heart valves, their manufacture, and methods of use are described. Generally, artificial heart valves can be deployed to replace or supplement defective heart valves in a patient. These artificial heart valves can comprise a frame with an inner skirt and leaflets. These inner skirt and leaflets can be generated from regenerative tissue to allow integration of the tissue with the body of a patient, while the frame can be generated from bioabsorbable material to allow dissolution of the frame over time. This combination of materials may allow for the artificial valve to grow with a patient and avoid costly and potentially dangerous replacement for patients receiving artificial valves.

公开(公告)号：US20230084393A1

公开(公告)日：2023-03-16

申请号：US18056691

申请日：2022-11-17

Applicant: Edwards Lifesciences Corporation

Inventor： Rafael Pintor ,  Mark Chau ,  Travis Zenyo Oba ,  August R. Yambao ,  Louis A. Campbell ,  Tammy Huntley ,  Qinggang Zeng ,  Carey L. Cristea ,  Faisal Kalam

IPC: A61F2/24

Abstract: A heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve has a base stent that is deployed at a treatment site, and a valve component configured to quickly connect to the base stent. The base stent may take the form of a self- or balloon-expandable stent that expands outward against the native valve with or without leaflet excision. The valve component has a non-expandable prosthetic valve and a self- or balloon-expandable coupling stent for attachment to the base stent, thereby fixing the position of the valve component relative to the base stent. The prosthetic valve may be a commercially available to valve with a sewing ring and the coupling stent attaches to the sewing ring. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment. A catheter-based system and method for deployment is provided.

公开(公告)号：US11412954B2

公开(公告)日：2022-08-16

申请号：US16356412

申请日：2019-03-18

Applicant: Edwards Lifesciences Corporation

Inventor： Louis A. Campbell ,  Travis Zenyo Oba ,  Rafael Pintor

IPC: A61B5/107 ,  A61F2/24 ,  A61B90/00 ,  A61B5/00

Abstract: An orifice-expanding device for measuring an expanded heart valve. The device includes a proximal handle having a shaft and an orifice-expanding device with a hub mounted to a distal end of the shaft and a plurality of arms evenly spaced around the axis and connected to the hub and extending therefrom in a distal direction to distal ends of the arms. The distal end of each arm has an expanding portion with an outer surface, the expanding portions being configured to move radially outward with respect to each other, wherein expansion of the expanding portions causes the distal ends of the arms to flex outward. A pressure-measuring device measures a pressure applied to the aortic valve annulus, and a size-measuring device measures a dimension of the aortic valve annulus after the annulus has been expanded.

公开(公告)号：US20220117738A1

公开(公告)日：2022-04-21

申请号：US17645940

申请日：2021-12-23

Applicant: Edwards Lifesciences Corporation

Inventor： Matthew T. Winston ,  Da-Yu Chang ,  Louis A. Campbell ,  James A. Davidson

IPC: A61F2/24

Abstract: Compressible heart valve annulus sizing templates suitable for minimally-invasive or otherwise reduced accessibility surgeries. The sizing templates may be folded, rolled, or otherwise compressed into a reduced configuration for passage through an access tube or other such access channel. Once expelled from the access tube the sizing templates expand to their original shape for use in sizing the annulus. The templates may be formed of an elastomeric polymer material such as silicone, a highly elastic metal such as NITINOL, or both. Grasping tabs or connectors for handles permit manipulation from outside the body. A NITINOL wireform may be compressed for passage through an access tube and expelled from the distal end thereof into a cloth cover to assume a sizer shape.

公开(公告)号：USD944398S1

公开(公告)日：2022-02-22

申请号：US29656215

申请日：2018-07-11

Applicant: Edwards Lifesciences Corporation

Designer： Louis A. Campbell

公开(公告)号：US11213385B2

公开(公告)日：2022-01-04

申请号：US16154353

申请日：2018-10-08

Applicant: Edwards Lifesciences Corporation

Inventor： Jeffrey S. Dove ,  Bin Tian ,  Ralph Schneider ,  Jeffrey S. Cohen ,  Ivan Jankovic ,  John F. Migliazza ,  Gregory A. Wright ,  James M. Young ,  Louis A. Campbell

IPC: A61F2/24 ,  A61L27/50 ,  A61L27/36 ,  A61B18/20 ,  B65B55/18 ,  B65B63/02 ,  A61F2/02 ,  A61F2/30

Abstract: Methods for the conditioning of bioprosthetic material employ bovine pericardial membrane. A laser directed at the fibrous surface of the membrane and moved relative thereto reduces the thickness of the membrane to a specific uniform thickness and smoothes the surface. The wavelength, power and pulse rate of the laser are selected which will smooth the fibrous surface as well as ablate the surface to the appropriate thickness. Alternatively, a dermatome is used to remove a layer of material from the fibrous surface of the membrane. Thinning may also employ compression. Stepwise compression with cross-linking to stabilize the membrane is used to avoid damaging the membrane through inelastic compression. Rather, the membrane is bound in the elastic compressed state through addition cross-linking. The foregoing several thinning techniques may be employed together to achieve strong thin membranes.

公开(公告)号：US20210244540A1

公开(公告)日：2021-08-12

申请号：US17244771

申请日：2021-04-29

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin ,  Louis A. Campbell

IPC: A61F2/24

Abstract: An annuloplasty ring assembly with detachable handle includes an annuloplasty ring configured to be secured to an annulus of a heart valve and an annuloplasty ring. The annuloplasty ring is attached to the ring holder such that the annuloplasty ring is in conformal contact along a lower surface of a peripheral edge portion of the ring holder. The assembly includes a handle adapter extending proximally from an upper proximal face of the ring holder. The handle adapter is also attached or attachable to a distal attachment end of the handle on one side and removably attached to the annuloplasty ring holder on another side.

公开(公告)号：US10799346B2

公开(公告)日：2020-10-13

申请号：US16248706

申请日：2019-01-15

Applicant: Edwards Lifesciences Corporation

Inventor： Rafael Pintor ,  Mark Chau ,  Travis Zenyo Oba ,  August R. Yambao ,  Louis A. Campbell ,  Tammy Huntley ,  Qinggang Zeng ,  Carey L. Cristea ,  Faisal Kalam

IPC: A61F2/24

Abstract: A heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve has a base stent that is deployed at a treatment site, and a valve component configured to quickly connect to the base stent. The base stent may take the form of a self- or balloon-expandable stent that expands outward against the native valve with or without leaflet excision. The valve component has a non-expandable prosthetic valve and a self- or balloon-expandable coupling stent for attachment to the base stent, thereby fixing the position of the valve component relative to the base stent. The prosthetic valve may be a commercially available to valve with a sewing ring and the coupling stent attaches to the sewing ring. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment. A catheter-based system and method for deployment is provided.