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71.发明申请公开(公告)号：US20200347342A1
公开(公告)日：2020-11-05
申请号：US16930269
申请日：2020-07-15
Applicant: Inscripta, Inc.
Inventor： Phillip Belgrader , Don Masquelier , Andrew Garst , Richard Fox
Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
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公开(公告)号：US10767169B1
公开(公告)日：2020-09-08
申请号：US16928742
申请日：2020-07-14
Applicant: Inscripta, Inc.
Inventor： Juhan Kim , Benjamin Mijts , Aamir Mir , Andrew Garst , Kyle Seamon
Abstract: The present disclosure provides novel RNA-guided enzymes for making rational and direct edits to the genome of live cells.
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73.发明申请公开(公告)号：US20200248131A1
公开(公告)日：2020-08-06
申请号：US16820324
申请日：2020-03-16
Applicant: Inscripta, Inc.
Inventor： Andrew Garst , Richard Fox , Phillip Belgrader , Don Masquelier
Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
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公开(公告)号：US20200231987A1
公开(公告)日：2020-07-23
申请号：US16819896
申请日：2020-03-16
Applicant: Inscripta, Inc.
Inventor： Andrew Garst , Ryan T. Gill , Tanya Elizabeth Warnecke Lipscomb
Abstract: Disclosed herein are nucleic acid-guided nucleases, guide nucleic acids, and targetable nuclease systems, and methods of use. Disclosed herein are engineered non-naturally occurring nucleic acid-guided nucleases, guide nucleic acids, and targetable nuclease systems, and methods of use. Targetable nuclease systems can be used to edit genetic targets, including recursive genetic engineering and trackable genetic engineering methods.
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75.发明申请公开(公告)号：US20200087613A1
公开(公告)日：2020-03-19
申请号：US16693630
申请日：2019-11-25
Applicant: Inscripta, Inc.
Inventor： Phillip Belgrader , Don Masquelier , Bruce Chabansky , Jorge Bernate , Andrew Garst , Richard Fox
Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
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Patent Agency Ranking
76.发明申请公开(公告)号：US20200078738A1
公开(公告)日：2020-03-12
申请号：US16687640
申请日：2019-11-18
Applicant: Inscripta, Inc.
Inventor： Don Masquelier , Phillip Belgrader , Andrew Garst , Richard Fox , Matthew Estes , Bruce Chabansky
IPC: B01D63/08
Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
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77.发明申请公开(公告)号：US20200063088A1
公开(公告)日：2020-02-27
申请号：US16597826
申请日：2019-10-09
Applicant: Inscripta, Inc.
Inventor： Andrew Garst , Richard Fox , Phillip Belgrader , Don Masquelier
Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
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公开(公告)号：US10337028B2
公开(公告)日：2019-07-02
申请号：US15896444
申请日：2018-02-14
Applicant: Inscripta, Inc.
Inventor： Ryan T. Gill , Andrew Garst , Tanya Elizabeth Warnecke Lipscomb
IPC: C12N15/90 , C12N15/11 , C12N15/10 , C12N15/82 , C12N15/85 , C12N9/22 , C12N5/14 , C12N5/16 , C12N5/22 , C12N15/09 , C12N15/52 , C12N15/63 , C12N15/79 , C12N15/70 , C12N15/81 , C12N15/113
Abstract: Disclosed herein are nucleic acid-guided nucleases, guide nucleic acids, and targetable nuclease systems, and methods of use. Disclosed herein are engineered non-naturally occurring nucleic acid-guided nucleases, guide nucleic acids, and targetable nuclease systems, and methods of use. Targetable nuclease systems can be used to edit genetic targets, including recursive genetic engineering and trackable genetic engineering methods.
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公开(公告)号：US20180371497A1
公开(公告)日：2018-12-27
申请号：US15896433
申请日：2018-02-14
Applicant: Inscripta, Inc.
Inventor： Ryan T. Gill , Andrew Garst , Tanya Elizabeth Warnecke Lipscomb
CPC classification number: C12N15/902 , C12N9/22 , C12N15/11 , C12N15/111 , C12N15/70 , C12N15/81 , C12N15/85 , C12N15/905 , C12N15/907 , C12N2310/20 , C12N2800/22
Abstract: Disclosed herein are nucleic acid-guided nucleases, guide nucleic acids, and targetable nuclease systems, and methods of use. Disclosed herein are engineered non-naturally occurring nucleic acid-guided nucleases, guide nucleic acids, and targetable nuclease systems, and methods of use. Targetable nuclease systems can be used to edit genetic targets, including recursive genetic engineering and trackable genetic engineering methods.
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公开(公告)号：US20250075232A1
公开(公告)日：2025-03-06
申请号：US18953294
申请日：2024-11-20
Applicant: Inscripta, Inc.
Inventor： Andrew Garst , Ryan T. Gill , Tanya Elizabeth Warnecke Lipscomb
IPC: C12N15/90 , C07K14/195 , C12N9/22 , C12N15/10 , C12N15/11 , C12N15/113 , C12N15/63 , C12N15/70 , C12N15/81 , C12N15/85
Abstract: Disclosed herein are nucleic acid-guided nucleases, guide nucleic acids, and targetable nuclease systems, and methods of use. Disclosed herein are engineered non-naturally occurring nucleic acid-guided nucleases, guide nucleic acids, and targetable nuclease systems, and methods of use. Targetable nuclease systems can be used to edit genetic targets, including recursive genetic engineering and trackable genetic engineering methods.
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