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公开(公告)号：US07163681B2
公开(公告)日：2007-01-16
申请号：US10720323
申请日：2003-11-24
申请人： Jill Giles-Komar , Linda Snyder , Mohit Trikha , Marian T. Nakada
发明人： Jill Giles-Komar , Linda Snyder , Mohit Trikha , Marian T. Nakada
IPC分类号： A61K39/395 , C07K16/28
CPC分类号： C07K16/2839 , A01K2217/05 , A01K2267/01 , A61K2039/505 , C07K16/2848 , C07K16/4258 , C07K2317/21 , C07K2317/565 , C07K2317/76 , C07K2317/92 , G01N33/5008 , G01N33/5029 , G01N33/68 , G01N2333/70546 , Y02A50/58
摘要： The present invention relates to at least one novel anti-alpha-V subunit antibodies, including isolated nucleic acids that encode at least one anti-alpha-V subunit antibody, alpha-V subunit, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
摘要翻译： 本发明涉及至少一种新的抗α-V亚基抗体，包括编码至少一种抗-α-V亚基抗体，α-V亚基，载体，宿主细胞，转基因动物或植物的分离的核酸，以及 制备和使用它们的方法，包括治疗组合物，方法和装置。
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公开(公告)号：US20050043517A1
公开(公告)日：2005-02-24
申请号：US10644308
申请日：2003-08-20
申请人： Jill Giles-Komar , Roberta Lamb , M. Lamine Mbow
发明人： Jill Giles-Komar , Roberta Lamb , M. Lamine Mbow
IPC分类号： C07K16/18 , C07K16/44 , C12P21/08 , A61K39/395 , C12P21/04
摘要： Methods for generating antibodies in rodents are disclosed. The antibodies are useful as therapeutic agents, diagnostic agents or research reagents.
摘要翻译： 公开了在啮齿动物中产生抗体的方法。 抗体可用作治疗剂，诊断剂或研究试剂。
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公开(公告)号：US08399630B2
公开(公告)日：2013-03-19
申请号：US13058453
申请日：2009-08-11
申请人： Ronald V. Swanson , Ellen Chi , Gopalan Raghunathan , Shanrong Zhao , Johan Fransson , Wendy Cordier , Hong Mimi Zhou , Juan C. Almagro , Linus Hyun , Jill Giles-Komar , Karyn T. O'Neil , Jill M. Carton , Alexey V. Teplyakov , Yiqing Feng
发明人： Ronald V. Swanson , Ellen Chi , Gopalan Raghunathan , Shanrong Zhao , Johan Fransson , Wendy Cordier , Hong Mimi Zhou , Juan C. Almagro , Linus Hyun , Jill Giles-Komar , Karyn T. O'Neil , Jill M. Carton , Alexey V. Teplyakov , Yiqing Feng
IPC分类号： A61K39/395 , C07K16/24 , C07H21/04 , C12N15/63 , C12P21/06
CPC分类号： C07K16/244 , A61K2039/505 , C07K2317/24 , C07K2317/34 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92 , C07K2319/21 , G01N2333/5437
摘要： The present invention relates to engineered antibodies immuno specific for human interleukin-13 (IL-13) protein or fragment thereof, as well as methods of making and using thereof, including therapeutic indications.
摘要翻译： 本发明涉及针对人白细胞介素-13（IL-13）蛋白或其片段免疫特异性的工程化抗体，以及其制备和使用方法，包括治疗适应症。
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公开(公告)号：US20120045438A1
公开(公告)日：2012-02-23
申请号：US13058453
申请日：2009-08-11
申请人： Ronald V. Swanson , Ellen Chi , Gopalan Raghunathan , Shanrong Zhao , Johan Fransson , Wendy Cordier , Hong Mimi Zhou , Juan C. Almagro , Linus Hyun , Jill Giles-Komar , Karyn T. O'Neil , Jill M. Carton , Alexey V. Teplyakov , Yiqing Feng
发明人： Ronald V. Swanson , Ellen Chi , Gopalan Raghunathan , Shanrong Zhao , Johan Fransson , Wendy Cordier , Hong Mimi Zhou , Juan C. Almagro , Linus Hyun , Jill Giles-Komar , Karyn T. O'Neil , Jill M. Carton , Alexey V. Teplyakov , Yiqing Feng
IPC分类号： A61K39/395 , C12N15/13 , C12N15/63 , A61P11/06 , C12P21/00 , G01N33/566 , A61K39/00 , A61P37/04 , C12N5/10 , C12N1/19 , C12N1/21 , A61P31/00 , A61P9/00 , A61P25/00 , A61P11/00 , A61P1/00 , A61P7/00 , A61P37/02 , A61P35/00 , A61P3/12 , C07K16/24
CPC分类号： C07K16/244 , A61K2039/505 , C07K2317/24 , C07K2317/34 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92 , C07K2319/21 , G01N2333/5437
摘要： The present invention relates to engineered antibodies immuno specific for human interleukin-13 (IL-13) protein or fragment thereof, as well as methods of making and using thereof, including therapeutic indications.
摘要翻译： 本发明涉及针对人白细胞介素-13（IL-13）蛋白或其片段免疫特异性的工程化抗体，以及其制备和使用方法，包括治疗适应症。
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公开(公告)号：US20100111959A1
公开(公告)日：2010-05-06
申请号：US12539630
申请日：2009-08-12
申请人： Ronald V. Swanson , Ellen Chi , Gopalan Raghunathan , Shanrong Zhao , Johan Fransson , Wendy Cordier , Hong Mimi Zhou , Juan C. Almagro , Linus Hyun , Jill Giles-Komar , Karyn T. O'Neil , Jill M. Carton , Alexey V. Teplyakov
发明人： Ronald V. Swanson , Ellen Chi , Gopalan Raghunathan , Shanrong Zhao , Johan Fransson , Wendy Cordier , Hong Mimi Zhou , Juan C. Almagro , Linus Hyun , Jill Giles-Komar , Karyn T. O'Neil , Jill M. Carton , Alexey V. Teplyakov
CPC分类号： C07K16/244 , A61K2039/505 , C07K2317/24 , C07K2317/34 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92 , C07K2319/21 , G01N2333/5437
摘要： The present invention relates to engineered antibodies immunospecific for human interleukin-13 (IL-13) protein or fragment thereof, as well as methods of making and using thereof, including therapeutic indications.
摘要翻译： 本发明涉及针对人白细胞介素-13（IL-13）蛋白或其片段免疫特异性的工程化抗体，以及其制备和使用方法，包括治疗适应症。
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76.发明申请公开(公告)号：US20100029002A1
公开(公告)日：2010-02-04
申请号：US12443492
申请日：2007-10-12
IPC分类号： C12N15/02
CPC分类号： C12N5/163 , C12N2500/90 , C12N2506/00
摘要： The present invention provides methods of enhancing hybridoma fusion efficiencies through cell synchronization of the fusion partners, in order to aid in production of antibodies.
摘要翻译： 本发明提供通过融合配偶体的细胞同步来增强杂交瘤融合效率的方法，以帮助抗体的产生。
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公开(公告)号：US07288390B2
公开(公告)日：2007-10-30
申请号：US09920267
申请日：2001-08-01
申请人： George Heavner , Jill Giles-Komar , Linda Snyder , Mohit Trikha
发明人： George Heavner , Jill Giles-Komar , Linda Snyder , Mohit Trikha
CPC分类号： G01N33/5008 , A01K2217/05 , A01K2267/01 , A61K2039/505 , C07K16/2839 , C07K2317/21 , C07K2317/565 , C07K2317/92 , G01N33/5029 , G01N33/68 , G01N2333/70546 , Y02A50/58
摘要： The present invention relates to at least one novel anti-dual integrin antibodies, including isolated nucleic acids that encode at least one anti-dual integrin antibody, dual integrin, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
摘要翻译： 本发明涉及至少一种新的抗双重整联蛋白抗体，包括编码至少一种抗双重整联蛋白抗体，双重整联蛋白，载体，宿主细胞，转基因动物或植物的分离核酸及其制备和使用方法 ，包括治疗组合物，方法和装置。
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公开(公告)号：US20070128203A1
公开(公告)日：2007-06-07
申请号：US11598411
申请日：2006-11-13
申请人： Jill Giles-Komar , Linda Snyder , Mohit Trikha , Marian Nakada
发明人： Jill Giles-Komar , Linda Snyder , Mohit Trikha , Marian Nakada
IPC分类号： A61K39/395 , A61K38/18 , A61K31/56 , A61K31/7052 , A61K31/137
CPC分类号： C07K16/2839 , A01K2217/05 , A01K2267/01 , A61K2039/505 , C07K16/2848 , C07K16/4258 , C07K2317/21 , C07K2317/565 , C07K2317/76 , C07K2317/92 , G01N33/5008 , G01N33/5029 , G01N33/68 , G01N2333/70546 , Y02A50/58
摘要： The present invention relates to at least one novel anti-alpha-V subunit antibodies, including isolated nucleic acids that encode at least one anti-alpha-V subunit antibody, alpha-V subunit, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
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79.发明申请公开(公告)号：US20050266004A1
公开(公告)日：2005-12-01
申请号：US10999866
申请日：2004-11-30
申请人： Jill Giles-Komar , Bernard Scallon , Ann Cai
发明人： Jill Giles-Komar , Bernard Scallon , Ann Cai
IPC分类号： A61K39/395 , C07K16/24 , C12N5/06 , G01N33/68
CPC分类号： C07K16/242 , A61K39/395 , C07K2317/24 , C07K2317/56 , C07K2317/76 , C07K2317/92 , G01N33/6863
摘要： The present invention relates to at least one novel anti-LTα antibody, including isolated nucleic acids that encode at least one anti-LTα antibody, LTα, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
摘要翻译： 本发明涉及至少一种新的抗LTalpha抗体，包括编码至少一种抗LTalpha抗体，LTα，载体，宿主细胞，转基因动物或植物的分离的核酸及其制备和使用方法，包括治疗 组合物，方法和装置。
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