公开(公告)号：US20100131027A1

公开(公告)日：2010-05-27

申请号：US12697853

申请日：2010-02-01

申请人： Alok Sathaye ,  Scott A. Meyer ,  Derek D. Bohn

发明人： Alok Sathaye ,  Scott A. Meyer ,  Derek D. Bohn

IPC分类号： A61N1/08

CPC分类号： A61N1/3712 ,  A61N1/3627

摘要： Methods and systems are directed to selecting from a variety of capture verification modes. A plurality of capture verification modes, including a beat by beat capture detection mode and a capture threshold testing mode without intervening beat by beat capture detection is provided. An efficacy of at least one of the capture verification modes is evaluated and, based on the evaluation, a capture verification mode is selected.

摘要翻译： 方法和系统旨在从各种捕获验证模式中进行选择。 提供了多个拍摄验证模式，包括拍拍拍摄检测模式和拍摄阈值测试模式，而不会通过拍摄捕获检测进行中间拍摄。 评估捕获验证模式中的至少一个的功效，并且基于评估，选择捕获验证模式。

公开(公告)号：US07574258B2

公开(公告)日：2009-08-11

申请号：US11300674

申请日：2005-12-14

申请人： Haris J. Sih ,  Scott A. Meyer ,  Paul A. Haefner

发明人： Haris J. Sih ,  Scott A. Meyer ,  Paul A. Haefner

IPC分类号： A61N1/08 ,  A61N1/39

CPC分类号： A61N1/3962

摘要： The present invention provides methods and systems for tachyarrhythmia therapy involving pacing the heart to prior to the application of a cardioversion/defibrillation shock. One or more pace pulses are delivered to the arrhythmic chamber or chambers. The pace pulses may be delivered to the heart at an adaptable rate selected to organize the electrical activity of the heart. If the pace pulses produce capture, cardioversion/defibrillation stimulation is delivered.

摘要翻译： 本发明提供了用于在应用心脏复律/除颤休克之前心脏起搏的快速性心律失常治疗的方法和系统。 将一个或多个步速脉冲输送到心律失常室或腔室。 速度脉冲可以以选择用于组织心脏的电活动的适应速率递送到心脏。 如果速度脉冲产生捕获，则输送心脏复律/除颤刺激。

公开(公告)号：US07457664B2

公开(公告)日：2008-11-25

申请号：US11125068

申请日：2005-05-09

申请人： Yi Zhang ,  Yinghong Yu ,  Aaron R. McCabe ,  Jiang Ding ,  Jeffrey E. Stahmann ,  Carlos Alberto Ricci ,  Scott A. Meyer

发明人： Yi Zhang ,  Yinghong Yu ,  Aaron R. McCabe ,  Jiang Ding ,  Jeffrey E. Stahmann ,  Carlos Alberto Ricci ,  Scott A. Meyer

IPC分类号： A61N1/365

CPC分类号： A61N1/3712 ,  A61N1/3627 ,  A61N1/365 ,  G06F19/00

摘要： Cardiac monitoring and/or stimulation methods and systems that provide one or more of monitoring, diagnosing, defibrillation, and pacing. Cardiac signal separation is employed to detect, monitor, track, and/or trend closed-loop cardiac resynchronization therapy using cardiac activation sequence information. Devices and methods involve sensing a plurality of composite cardiac signals using a plurality of electrodes, the electrodes configured for implantation in a patient. A source separation is performed using the sensed plurality of composite cardiac signals, producing one or more cardiac signal vectors associated with all or a portion of one or more cardiac activation sequences. A cardiac resynchronization therapy is adjusted using one or both of the one or more cardiac signal vectors and the signals associated with the one or more cardiac signal vectors. In further embodiments, the cardiac resynchronization therapy may be initiated, terminated, or one or more parameters of the resynchronization therapy may be altered.

摘要翻译： 提供一种或多种监测，诊断，除颤和起搏的心脏监测和/或刺激方法和系统。 心脏信号分离用于使用心脏激活序列信息来检测，监测，跟踪和/或趋向闭环心脏再同步治疗。 设备和方法包括使用多个电极感测多个复合心脏信号，所述电极被配置用于植入患者体内。 使用所感测的多个复合心脏信号进行源分离，产生与一个或多个心脏激活序列的全部或一部分相关联的一个或多个心脏信号载体。 使用一个或多个心脏信号向量和与一个或多个心脏信号载体相关联的信号中的一个或两个来调整心脏再同步治疗。 在另外的实施方案中，心脏再同步治疗可以被启动，终止，或者可以改变再同步治疗的一个或多个参数。

公开(公告)号：US06575572B2

公开(公告)日：2003-06-10

申请号：US09960113

申请日：2001-09-21

申请人： Ming Lai ,  Jay Wei ,  Scott A. Meyer ,  James P. Foley ,  Jochen M. Horn

发明人： Ming Lai ,  Jay Wei ,  Scott A. Meyer ,  James P. Foley ,  Jochen M. Horn

IPC分类号： A61B310

CPC分类号： A61B3/1015 ,  A61B3/156

摘要： Embodiments of the present invention provide a method and apparatus for measurement of aberration of an eye. One or more embodiments provide an aberration measurement instrument that enables measurement wherein Hartmann-Shack spots have reduced speckle; one or more embodiments provide an aberration measurement instrument that enables measurement of an eye having a large diopter power variation over different zones of the eye; one or more embodiments provide an aberration measurement instrument that enables measurement with accommodation control; one or more embodiment provide an aberration measurement instrument wherein radiation reflected by a cornea and radiation scattered by intra-ocular elements are blocked; and one or more embodiment provide an aberration measurement instrument wherein a hazy background produced by radiation multiply scattered within an eye is reduced.

公开(公告)号：US09144375B2

公开(公告)日：2015-09-29

申请号：US12630656

申请日：2009-12-03

申请人： Rudolf Murai Von Bünau ,  Burkhart Wagner ,  Scott A. Meyer ,  Xunchang Chen

发明人： Rudolf Murai Von Bünau ,  Burkhart Wagner ,  Scott A. Meyer ,  Xunchang Chen

IPC分类号： A61B3/00 ,  A61F2/16

CPC分类号： A61B3/0025 ,  A61B3/1005 ,  A61B3/117 ,  A61B3/1173 ,  A61F2/16 ,  A61F2/1605 ,  A61F2240/002

摘要： For the pre-operative calculation of the power of an intraocular lens, three input parameters are needed: the axial length of the eye (AL), the refractive power of the cornea, and the distance between the front of the cornea and the back focal plane of the intraocular lens, the so-called effective lens position (ELP). The invention shows a novel approach to the determination of the ELP.

摘要翻译： 对于术前计算眼内透镜的功率，需要三个输入参数：眼睛的轴向长度（AL），角膜的屈光度以及角膜前部和背部焦点之间的距离 眼内透镜的平面，所谓的有效透镜位置（ELP）。 本发明显示了一种确定ELP的新方法。

公开(公告)号：US09055892B2

公开(公告)日：2015-06-16

申请号：US13453856

申请日：2012-04-23

申请人： Harihar Narasimha-Iyer ,  Scott A. Meyer

发明人： Harihar Narasimha-Iyer ,  Scott A. Meyer

IPC分类号： A61B3/14 ,  A61B3/10 ,  A61B3/113 ,  A61B3/117 ,  A61B3/12

CPC分类号： A61B3/152 ,  A61B3/102 ,  A61B3/113 ,  A61B3/117 ,  A61B3/12

摘要： Systems and methods for improving ophthalmic imaging by correlating the location of a measurement on the pupil of the eye with a quality of the measurement and further controlling subsequent measurements based on the quality are presented. Aspects of the invention include obtaining optical coherence tomography (OCT) measurements through cataracts or other media opacities, obtaining B-scans with minimized tilt, and automated OCT data acquisition of select structures in the eye. Embodiments of the invention directed towards imaging tissues with angle dependent layer contrast and mapping the size and location of cataracts in the eye are also described.

摘要翻译： 提出了通过将眼睛瞳孔上的测量位置与测量质量相关联并且基于质量进一步控制后续测量来改善眼科成像的系统和方法。 本发明的方面包括通过白内障或其他媒体不透明度获得光学相干断层摄影（OCT）测量，以最小化倾斜获得B扫描，以及眼睛中选择结构的自动OCT数据采集。 还描述了针对具有角度依赖层对比度的成像组织并且将眼睛中的白内障的大小和位置映射的本发明的实施例。

公开(公告)号：US08630697B2

公开(公告)日：2014-01-14

申请号：US13531034

申请日：2012-06-22

申请人： Scott A. Meyer ,  Xing Wei

发明人： Scott A. Meyer ,  Xing Wei

IPC分类号： A61B5/00

CPC分类号： A61B3/102

摘要： The present invention provides for the detection and display of polarization scrambling tissue without resolving the polarization state of the backscattered imaging beam. In one embodiment, we illuminate the tissue using two different polarizations. A first polarization determines a first image of high intensity while the second polarization determines a second image of low intensity. Comparison and combination of the first and second images determines tissue which scrambles the polarization in neighboring detection cells.

摘要翻译： 本发明提供了偏振加扰组织的检测和显示，而不分辨背散射成像束的偏振状态。 在一个实施例中，我们使用两种不同的偏振照亮组织。 第一偏振确定高强度的第一图像，而第二偏振确定低强度的第二图像。 第一和第二图像的比较和组合确定在相邻检测单元中加扰极化的组织。

公开(公告)号：US08521284B2

公开(公告)日：2013-08-27

申请号：US10735519

申请日：2003-12-12

申请人： Jaeho Kim ,  Joseph Bocek ,  Scott A. Meyer ,  Paul A. Haefner ,  Haris J. Sih

发明人： Jaeho Kim ,  Joseph Bocek ,  Scott A. Meyer ,  Paul A. Haefner ,  Haris J. Sih

IPC分类号： A61N1/36

CPC分类号： A61N1/371 ,  A61B5/04525 ,  A61B5/7217 ,  A61B5/7264 ,  A61N1/368

摘要： Methods and devices for classifying a cardiac pacing response involve using a first electrode combination for pacing and a second electrode combination for sensing a cardiac signal following pacing. The cardiac response to pacing may be classified using the sensed cardiac signal. One process involves using the sensed cardiac signal to detect the cardiac response as a fusion/pseudofusion beat. Another process involves using the sensed cardiac signal to classify the cardiac response to pacing as one of at least three cardiac response types.

摘要翻译： 用于分类心脏起搏反应的方法和装置涉及使用用于起搏的第一电极组合和用于感测起搏后的心脏信号的第二电极组合。 可以使用感测到的心脏信号来分类对起搏的心脏反应。 一个过程涉及使用感测到的心脏信号来检测作为融合/假融合搏动的心脏反应。 另一个过程涉及使用所感测到的心脏信号将心脏起搏应答分为至少三种心脏反应类型之一。

公开(公告)号：US08416991B2

公开(公告)日：2013-04-09

申请号：US13488280

申请日：2012-06-04

申请人： Matthew J. Everett ,  Scott A. Meyer ,  Paul F. Stetson ,  Yan Zhou

发明人： Matthew J. Everett ,  Scott A. Meyer ,  Paul F. Stetson ,  Yan Zhou

IPC分类号： G06K9/00 ,  G01B9/02

CPC分类号： A61B5/0066 ,  G06T7/0014 ,  G06T19/00 ,  G06T2200/24 ,  G06T2207/10101 ,  G06T2207/30041 ,  G06T2210/41

摘要： The present invention discloses a method for generating elevation maps or images of a tissue layer/boundary with respect to a fitted reference surface, comprising the steps of finding and segmenting a desired tissue layer/boundary; fitting a smooth reference surface to the segmented tissue layer/boundary; calculating elevations of the same or other tissue layer/boundary relative to the fitted reference surface; and generating maps of elevation relative to the fitted surface. The elevation can be displayed in various ways including three-dimensional surface renderings, topographical contour maps, contour maps, en-face color maps, and en-face grayscale maps. The elevation can also be combined and simultaneously displayed with another tissue layer/boundary dependent set of image data to provide additional information for diagnostics.

摘要翻译： 本发明公开了一种用于产生相对于拟合的参考表面的组织层/边界的仰角图或图像的方法，包括以下步骤：找到并分割所需的组织层/边界; 将平滑的参考表面拟合到分段的组织层/边界; 计算相对于拟合参考表面的相同或其它组织层/边界的高度; 并产生相对于拟合表面的高程图。 高程可以以各种方式显示，包括三维表面效果图，地形轮廓图，轮廓图，面孔颜色图和面对灰度图。 也可以将高程组合并同时显示另一个组织层/边界依赖的图像数据集，以提供用于诊断的附加信息。

公开(公告)号：US08208996B2

公开(公告)日：2012-06-26

申请号：US12381406

申请日：2009-03-10

申请人： Scott A. Meyer ,  Xing Wei

发明人： Scott A. Meyer ,  Xing Wei

IPC分类号： G01J4/00 ,  G01B9/02 ,  A61B5/00

CPC分类号： A61B3/102

摘要： The present invention provides for the detection and display of polarization scrambling tissue without resolving the polarization state of the backscattered imaging beam. In one embodiment, we illuminate the tissue using two different polarizations. A first polarization determines a first image of high intensity while the second polarization determines a second image of low intensity. Comparison and combination of the first and second images determines tissue which scrambles the polarization in neighboring detection cells.

摘要翻译： 本发明提供了偏振加扰组织的检测和显示，而不分辨背散射成像束的偏振状态。 在一个实施例中，我们使用两种不同的偏振照亮组织。 第一偏振确定高强度的第一图像，而第二偏振确定低强度的第二图像。 第一和第二图像的比较和组合确定在相邻检测单元中加扰极化的组织。