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公开(公告)号：US20010041737A1
公开(公告)日：2001-11-15
申请号：US09883528
申请日：2001-06-18
发明人： Richard M. Poche
IPC分类号： A01N043/04 , A01N037/18 , A01N043/50 , A01N043/16
CPC分类号： A01N25/004 , A01N43/16 , A01N61/00 , A01N43/50 , A01N37/44 , A01N2300/00
摘要： The presence of a small amount of an antibiotic, such as metronidazole or a salt or derivative thereof, in warfarin-containing rodent baits enhances the toxicity of warfarin against rodents which have heretofore shown apparent resistance to warfarin.
摘要翻译： 在含有华法林的啮齿动物诱饵中存在少量抗生素，如甲硝唑或其盐或衍生物，增强了华法林对以前显示出对华法林的抗性的啮齿动物的毒性。
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72.发明授权Botanical oils as blooming agents in germicidal hard surface cleaning compositions 有权植物油作为灭菌剂在杀菌硬表面清洗组合物中
公开(公告)号：US6143703A
公开(公告)日：2000-11-07
申请号：US265667
申请日：1999-03-10
摘要： The present invention provides aqueous concentrated liquid disinfectant compositions which blooms when added to a larger volume of water which comprise:botanical oil constituent;a germicide constituent, preferably a germicidal cationic surfactant, and most preferably a quaternary ammonium compound having germicidal properties;organic solvent constituent;at least one botanical oil solubilizing surfactant, preferably selected from amine oxides, alkylpolyoxycarboxylates and alkylarylpolyoxycarboxylates;and further conventional optional constituents including chelating agents, coloring agents, light stabilizers, fragrances, thickening agents, hydrotropes, pH adjusting agents, pH buffers one or more detersive surfactant constituents and the like. The concentrate compositions do not include a pine oil.
摘要翻译： 本发明提供了当加入到更大体积的水中时盛开的含水浓缩液体消毒剂组合物，其包含植物油成分; 杀菌剂组分，优选杀菌阳离子表面活性剂，最优选具有杀菌性质的季铵化合物; 有机溶剂成分; 至少一种植物油增溶表面活性剂，优选选自氧化胺，烷基多氧基羧酸盐和烷基芳基聚氧化羧酸盐; 以及其它常规的任选成分，包括螯合剂，着色剂，光稳定剂，香料，增稠剂，水溶助长剂，pH调节剂，pH缓冲剂，一种或多种去污表面活性剂组分等。 浓缩物组合物不包括松油。
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73.发明授权Ready to use aqueous hard surface cleaning and disinfecting compositions containing hydrogen peroxide 有权准备使用含有过氧化氢的水性硬表面清洁和消毒组合物
公开(公告)号：US6106774A
公开(公告)日：2000-08-22
申请号：US227464
申请日：1999-01-08
CPC分类号： C11D3/2006 , C11D3/2068
摘要： Disclosed are ready to use aqueous cleaning and disinfecting composition which includes the following constituents by weight:0.1-20%wt. of a C.sub.1 -C.sub.6 monohydric alcohol;1.0-10%wt. of a glycol ether, or butoxypropanol or propoxypropanol;0.1-12%wt. of a detersive surfactant particularly those selected from anionic, cationic, nonionic and amphoteric surfactants;0.1-10%wt. of hydrogen peroxide;0.1-7%wt. of an acid;to 100%wt. water;wherein the said composition is at an acidic pH. The composition may include minor amounts of further conventional additives.Methods of cleaning and disinfecting surfaces are also disclosed.
摘要翻译： 公开了使用含水清洁和消毒组合物，其包含以下重量份数：0.1-20重量％ 的C1-C6一元醇; 1.0-10％重量 乙二醇醚或丁氧丙醇或丙氧丙醇; 0.1-12％重量 的洗涤表面活性剂，特别是选自阴离子，阳离子，非离子和两性表面活性剂的那些; 0.1-10％重量 的过氧化氢; 0.1-7％重量 的酸 至100重量％ 水; 其中所述组合物处于酸性pH。 组合物可以包含少量的其它常规添加剂。 还公开了清洁和消毒表面的方法。
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74.发明授权
公开(公告)号：US6090771A
公开(公告)日：2000-07-18
申请号：US360667
申请日：1999-07-26
IPC分类号： C11D1/62 , C11D1/72 , C11D1/75 , C11D1/83 , C11D3/20 , C11D3/30 , C11D3/43 , C11D3/48 , C11D11/00
CPC分类号： C11D1/835 , C11D1/94 , C11D11/0058 , C11D3/2068 , C11D3/30 , C11D3/43 , C11D3/48 , C11D1/62 , C11D1/72 , C11D1/75
摘要： Aqueous based cleaning compositions simultaneously featuring disinfecting, low residue deposit and good cleaning characteristics are provided. The compositions include one or more quaternary amine compounds as disinfecting active agents, an organic solvent system which includes glycol mono-n-butyl ether or a binary system including a glycol ether with a linear primary alcohol, and either one or more betaines, or one or more amine oxides as a surfactant constituent.
摘要翻译： 提供同时具有消毒，低残留物沉积和良好清洁特性的基于水的清洁组合物。 组合物包括一种或多种季铵化合物作为消毒活性剂，包括二醇单正丁基醚或包含二醇醚与二元醇的线性伯醇的二元体系的有机溶剂系统，以及一种或多种甜菜碱，或一种 或更多的氧化胺作为表面活性剂成分。
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公开(公告)号：US6085026A
公开(公告)日：2000-07-04
申请号：US665856
申请日：1996-06-19
申请人： Randall Lee Hammons , Manhar Patel
发明人： Randall Lee Hammons , Manhar Patel
CPC分类号： A61L9/03
摘要： An electrically heated apparatus for dispensing fragrancing materials and other volatile substances to an enclosed volume such as the interior of a room which includes a base having a base portion which is generally planar in structure having a top surface, and a bottom surface from which extends perpendicularly two (or more) suitably dimensioned electrical plugs. The base portion further includes incorporated within its construction a heating means which, when the electrical plugs are connected to a suitable electrical source, said heating means is energized, resulting in the heating of the base portion. Further, the base portion of the invention includes a radiator means. The apparatus further includes a volatile substance container which contains a quantity of a volatile substance such as a fragrance or perfume, a disinfecting composition, or an insecticide. The radiator means provides a surprisingly uniform temperature across the top surface of the base portion.
摘要翻译： 一种用于将分散材料和其它挥发性物质分配到诸如房间内部的封闭体积的电加热设备，其包括具有基本部分的基部，该基部具有顶部表面的大致平面的基部，以及垂直地从其延伸的底表面 两个（或更多）适当尺寸的电插头。 底座部分还包括结合在其结构内的加热装置，当电插塞连接到合适的电源时，所述加热装置被通电，导致基部的加热。 此外，本发明的基部包括散热器装置。 该装置还包括含有一定量的挥发性物质如香料或香料，消毒组合物或杀虫剂的挥发性物质容器。 散热器装置在基部的顶表面上提供惊人的均匀温度。
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公开(公告)号：US07985420B2
公开(公告)日：2011-07-26
申请号：US10406574
申请日：2003-04-04
IPC分类号： A61K9/22
CPC分类号： A61K9/2027 , A61K9/2054 , A61K9/209 , A61K9/5084 , A61K31/09 , A61K31/137 , A61K31/485 , A61K31/495 , A61K2300/00
摘要： The invention relates to a novel pharmaceutical sustained release formulation of guaifenesin and pseudoephedrine. The formulation may comprise a hydrophilic polymer, preferably a hydroxypropyl methylcellulose, and a water-insoluble polymer, preferably an acrylic resin, in a ratio range of about one-to-one (1:1) to about nine-to-one (9:1), more preferably a range of about three-to-two (3:2) to about six-to-one (6:1), and most preferably in a range of about two-to-one (2:1) to about four-to-one (4:1) by weight. This formulation capable of providing therapeutically effective bioavailability of guaifenesin for at least twelve hours after dosing in a human subject. The invention also relates to a modified release product which has two portions: a first portion having an immediate release formulation of guaifenesin and a second portion having a sustained release formulation of guaifenesin, wherein one or both portions further comprises pseudoephedrine. The modified release product has a maximum guaifenesin serum concentration equivalent to that of an immediate release guaifenesin tablet, and is capable of providing therapeutically effective bioavailability of guaifenesin for at least twelve hours after dosing in a human subject.
摘要翻译： 本发明涉及愈创甘油醚和伪麻黄碱的新型药物缓释制剂。 制剂可包含亲水性聚合物，优选羟丙基甲基纤维素和水不溶性聚合物，优选丙烯酸树脂，其比例范围为约一对一（1：1）至约九对一（9 ：1），更优选约三至二（3:2）至约六对一（6:1）的范围，最优选在约二至一（2:1）的范围内 ）至约四对一（4:1）重量比。 该制剂能够在给予人受试者后至少十二个小时提供愈创甘油的治疗有效的生物利用度。 本发明还涉及一种具有两部分的改性释放产物：第一部分具有愈创甘油醚的立即释放制剂，第二部分具有愈创甘油醚的缓释制剂，其中一个或两个部分还包含伪麻黄碱。 改性释放产物具有与立即释放愈创甘油醚片剂相当的最大愈创甘油醚血清浓度，并且能够在给予人受试者后至少十二个小时提供愈创甘油的治疗有效的生物利用度。
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公开(公告)号：US20110052689A1
公开(公告)日：2011-03-03
申请号：US12940781
申请日：2010-11-05
CPC分类号： A61K9/2086 , A61K9/2027 , A61K9/2054 , A61K9/209 , A61K9/5084 , A61K31/09 , A61K31/137 , A61K31/485 , A61K31/495 , A61K2300/00
摘要： The invention relates to a novel pharmaceutical sustained release formulation of guaifenesin. The formulation may comprise a hydrophilic polymer, preferably a hydroxypropyl methylcellulose, and a water-insoluble polymer, preferably an acrylic resin, in a ratio range of about one-to-one (1: 1) to about nine-to-one (9: 1), more preferably a range of about three-to-two (3:2) to about six-to-one (6: 1), and most preferably in a range of about two-to-one (2: 1) to about four-to-one (4: 1) by weight. This formulation capable of providing therapeutically effective bioavailability of guaifenesin for at least twelve hours after dosing in a human subject. The invention also relates to a modified release product which has two portions: a first portion having an immediate release formulation of guaifenesin and a second portion having a sustained release formulation of guaifenesin. The modified release product has a maximum guaifenesin serum concentration equivalent to that of an immediate release guaifenesin tablet, and is capable of providing therapeutically effective bioavailability of guaifenesin for at least twelve hours after dosing in a human subject.
摘要翻译： 本发明涉及愈创甘油醚的新型药物缓释制剂。 制剂可包含亲水性聚合物，优选羟丙基甲基纤维素和水不溶性聚合物，优选丙烯酸树脂，其比例范围为约一对一（1：1）至约九对一（9 ：1），更优选约三至二（3:2）至约六对一（6:1）的范围，最优选在约二至一（2:1）的范围内 ）至约四对一（4:1）重量比。 该制剂能够在给予人受试者后至少十二个小时提供愈创甘油的治疗有效的生物利用度。 本发明还涉及一种具有两部分的改良释放产物：第一部分具有愈创甘油醚的立即释放制剂，第二部分具有愈创甘油醚的缓释制剂。 改性释放产物具有与立即释放愈创甘油醚片剂相当的最大愈创甘油醚血清浓度，并且能够在给予人受试者后至少十二个小时提供愈创甘油的治疗有效的生物利用度。
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公开(公告)号：US20100308125A1
公开(公告)日：2010-12-09
申请号：US12675199
申请日：2008-08-26
申请人： John Depiano , Deirdre McKeown
发明人： John Depiano , Deirdre McKeown
IPC分类号： B05B1/08
CPC分类号： B05B11/047 , B05B1/08 , B05B11/0059 , B65D83/36
摘要： The present invention provides a compressible spray dispensing container which includes a quantity of a liquid treatment composition contained therein, and a dispensing means which dispensing means includes a fluidic oscillator which provides for oscillation of the liquid exiting the dispensing means, and particularly via a nozzle.
摘要翻译： 本发明提供了一种可压缩喷雾分配容器，其包括一定量的液体处理组合物，以及分配装置，其分配装置包括流体振荡器，其提供离开分配装置的液体的振荡，特别是通过喷嘴。
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公开(公告)号：USD626004S1
公开(公告)日：2010-10-26
申请号：US29333053
申请日：2009-03-02
申请人： James E. McCay , Anne E. Nixon
设计人： James E. McCay , Anne E. Nixon
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公开(公告)号：US20100263693A1
公开(公告)日：2010-10-21
申请号：US12675170
申请日：2008-08-15
申请人： Dilip Shanker Mathur
发明人： Dilip Shanker Mathur
摘要： An improved hard surface treatment compositions which comprises (preferably consists essentially of; yet more preferably consists of) the following constituents: a detersive anionic surfactant; a detersive nonionic surfactant; an alkylene glycol ether solvent; a phenyl containing glycol ether solvent; an organic acid, preferably an organic acid selected from citric acid, lactic acid and mixtures thereof; optionally but preferably a film forming polymer based on quaternized copolymers of vinylpyrrolidone and dimethylaminoethyl methacrylate, optionally one or more further constituents which may improve aesthetic or functional features of the compositions, and, water.
摘要翻译： 改进的硬表面处理组合物，其包含（优选基本上由...组成;但更优选由以下组分组成）：去污阴离子表面活性剂; 去污非离子表面活性剂; 亚烷基二醇醚溶剂; 含苯基的乙二醇醚溶剂; 有机酸，优选选自柠檬酸，乳酸及其混合物的有机酸; 任选但优选基于乙烯基吡咯烷酮和甲基丙烯酸二甲基氨基乙酯的季铵化共聚物的成膜聚合物，任选地一种或多种可以改善组合物的美学或功能特征的其它组分，以及水。
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