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公开(公告)号：US20230052143A1
公开(公告)日：2023-02-16
申请号：US17980308
申请日：2022-11-03
Applicant: VisCardia, Inc.
Inventor： Peter T. Bauer , Timothy Wheeler
Abstract: Devices, systems and methods provide forms of asymptomatic diaphragmatic stimulation (ADS) therapy that affect pressures within the intrathoracic cavity, including: 1) dual-pulse ADS therapy, during which a first ADS pulse is delivered during a diastolic phase of a cardiac cycle and a second ADS pulse is delivered during a systolic phase, 2) paired-pulse ADS therapy, during which a first ADS pulse is delivered, closely followed by a second ADS pulse, with the second ADS pulse functioning to extend or enhance a phase of a transient, partial contraction of the diaphragm, and 3) multiple-pulse ADS therapy, during which a stream of ADS pulses is delivered, wherein the time between pulses is based on heart rate. Devices, systems and methods also monitor electromyography (EMG) activity of the diaphragm relative to baseline activity to assess the health of a diaphragm subject to ADS therapy and to adjust ADS therapy parameters or sensing parameters.
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公开(公告)号：US20230046820A1
公开(公告)日：2023-02-16
申请号：US17798554
申请日：2021-02-10
Inventor： Abraham Akinin , Gert Cauwenberghs , Chul Kim , Patrick Mercier , Hiren Thacker
Abstract: Apparatuses and methods are disclosed for efficient wireless powering of an electrical load with precise external control over pulsed voltage waveform and metering of charge delivered. The system interfaces to an inductive coil for RF power delivery from an external duty-cycled RF power transmitter, and the electrical load. The electrical load may be a photosensitive array of electrodes for an optically addressed, electrically activated retinal prosthesis. The voltage waveform to activate the load is controlled by the transmitted RF amplitude, including switching between cathodic and anodic phases of electrical stimulation. Charge delivered to the load is quantified as discharge events through a series capacitor, transmitted by backtelemetry to the receiver for continuous monitoring throughout the stimulation phases. The subject disclosure further provides for calibration of voltage amplitude and charge metering, to compensate for variable wireless link and load conditions, through additional stimulation phases with a supplementary load with known and stable characteristics.
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73.发明授权公开(公告)号：US11577084B2
公开(公告)日：2023-02-14
申请号：US16842904
申请日：2020-04-08
Applicant: Pacesetter, Inc.
Inventor： Dean P. Andersen
Abstract: An implantable medical device (IMD) and method are provided. The IMD includes a sensing channel configured to obtain biological signals indicative of biological behavior of an anatomy of interest over a period of time. The biological behavior has a feature of interest that repeats over time. The biological signals have clinically relevant (CR) segments that include information related to the feature of interest. The biological signals have non-clinically relevant (NCR) segments that do not include information related to the feature of interest. At least one of circuitry or a processor are configured to compare the biological signals to an amplitude window to distinguish the CR segments from the NCR segments, save to memory the CR segments and delete the NCR segments, save to memory time information indicative of a duration of the NCR segments that were deleted and to form a lossy compressed data set for the biological signals.
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公开(公告)号：US11571579B2
公开(公告)日：2023-02-07
申请号：US16128283
申请日：2018-09-11
Inventor： G. Karl Steinke , Ara Sarian
Abstract: The types of electrode leads that are connected to an implantable medical device are determined based on electrical parameters that are measured at the electrodes that are positioned on the leads. The different types of known electrode leads have different physical electrode arrangements that impact the measured electrical parameters. Properties in the measured electrical parameters that are indicative of the physical arrangements of electrodes of known types of electrode leads are utilized to determine the types of leads that are connected to the implantable medical device.
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公开(公告)号：US20230035441A1
公开(公告)日：2023-02-02
申请号：US17642062
申请日：2020-09-10
Applicant: ESQURE ADVANCED MEDICAL DEVICES LTD.
Inventor： Itshak BEN YESHA , Zvi NAHUM
Abstract: A method for stimulating a group of nerves, the method comprising: placing at least one electrode in contact with skin of a subject; applying an electrical signal to the subject through the at least one electrode, wherein the electrical signal comprises a series of pulses; and continuously randomly varying at least one of the following signal parameters: (i) a duration of each of the pulses, (ii) a time interval between each pair of pulses, and (iii) an energy value of each of the pulses, while maintaining a number of pulses per second of the electrical signal above a predetermined minimum number of pulses per second, and the energy value per pulse above a predetermined minimum energy value.
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Patent Agency Ranking
76.发明申请公开(公告)号：US20230031498A1
公开(公告)日：2023-02-02
申请号：US17878608
申请日：2022-08-01
Applicant: MedAmp Electronics LLC
Inventor： RICHARD B. RUSE , E. DAVID CRAWFORD , WILLIAM L. NABORS , SEAN BRUGMAN , SCOTT J. BOHANAN , PAUL ARANGUA
Abstract: A method and apparatus for treating bone or other infection in a patient to minimize the number of limb amputations which employs a unique, three-dimensional software-controlled electronic phased array amplifier system using arbitrary waveforms that dynamically and proportionally steer electrical currents by using two or more current vector paths, sequentially or simultaneously, through a defined infected area containing electrically-conductive ionic solutions so as to obtain 100% treatment using low or high voltage, low current that delivers electrical stimulation (ES) using a low DC current through and or around the defined infection treatment area. The minimally invasive treatment of the infection requires no radiation or chemotherapy that could be harmful to the patient.
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公开(公告)号：US20220409917A1
公开(公告)日：2022-12-29
申请号：US17822346
申请日：2022-08-25
Applicant: Regenesis Biomedical, Inc.
Inventor： Martin L. KIRK , Shanil MERCHANT , Joseph E. BRIGHT , Randy CHAVEZ , Scott S. BROOKS , Scott COWLING , Frank E. CONTRERAS , Charles MESAROSH
Abstract: Described herein are high-power pulsed electromagnetic field (PEMF) applicator systems. The systems can comprise a base housing including a controller configured to generate a low-power control signal and one or more applicators coupled to the base. Each applicator can include a drive circuitry comprising a generator configured to receive the low-power control signal and to produce, in the applicator, a high-power pulsed electromagnetic field signal based on the low-power control signal. The high-power pulsed electromagnetic field signal can has a power of greater than 40 W. Each applicator can further include a coil circuit configured to emit the high-power pulsed electromagnetic field signal, and an electromagnetic energy shield disposed between the drive circuitry and the coil circuit.
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公开(公告)号：US11534597B2
公开(公告)日：2022-12-27
申请号：US16879297
申请日：2020-05-20
Applicant: Medtronic, Inc.
Abstract: Techniques for providing therapy to a patient via electrical stimulation are described. The techniques include, for example, determining, relative to a start time of providing the electrical stimulation, one or more efficacy times that correspond to an efficacy indicator, determining, according to the efficacy times, efficacy data items for the patient, comparing the efficacy data items with the efficacy indicator, and generating, based on the comparison, a prediction of an expected response to the therapy manifesting in the patient at a prospective time.
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公开(公告)号：US11511110B2
公开(公告)日：2022-11-29
申请号：US16454578
申请日：2019-06-27
Applicant: Viveve, Inc.
Inventor： Deborah Wilkerson , Stacie Bell , Bruce Baldwin Allan
Abstract: Methods for treating urinary stress incontinence by non-invasively delivering energy to one or more submucosal regions of vaginal tissue to induce remodeling within the vaginal tissue are provided. In some embodiments, the energy delivery results in heating of the target tissue to a temperature that ranges from about 38° C. to about 46° C. In some embodiments, the subject methods involve cooling a mucosal epithelial layer over the vaginal tissue. In some embodiments, a reverse thermal gradient is produced as the mucosal epithelium is cooled while energy is delivered to the underlying vaginal tissue.
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公开(公告)号：US11504531B2
公开(公告)日：2022-11-22
申请号：US17575084
申请日：2022-01-13
Applicant: BATTELLE MEMORIAL INSTITUTE
Inventor： David A. Friedenberg , Po-Hsu Chen , Samuel Colachis , Nicholas Annetta , Douglas E. Boyd , Collin Dunlap , Ian W. Baumgart , Herbert S. Bresler
Abstract: A functional electrical stimulation (FES) device includes electrodes arranged to apply functional electrical stimulation to a body part of the user. FES stimulation is performed by: receiving values of a set of user metrics for the user; receiving a target position of the body part represented as values for a set of body part position measurements; determining a user-specific energization pattern for producing the target position based on the received target position and the received values of the set of user metrics for the user; and energizing the electrodes of the FES device in accordance with the determined user-specific energization pattern. The determination may utilize an FES calibration database with records having fields containing: values of the set of user metrics for reference users; energization patterns; and values of the set of body part position metrics for positions assumed by the body part in response to applying the energization patterns.
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