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81.发明授权Polyester based degradable materials and implantable biomedical articles formed therefrom 有权聚酯基可降解材料和由其形成的植入式生物医学制品公开(公告)号：US08383725B2
公开(公告)日：2013-02-26
申请号：US13204774
申请日：2011-08-08
Applicant: Valerie Ashby , David Olson
Inventor： Valerie Ashby , David Olson
CPC classification number: C08G63/52 , A61L27/18 , A61L31/06 , C08G63/672 , C08L67/04
Abstract: A method of making an aliphatic polyester prepolymer, comprising: reacting, alone or in combination with other reactants, a diol with at least a first diacid (or a diester of said first diacid) to produce an aliphatic polyester prepolymer. The first diacid is preferably a trans-beta-hydromuconic acid (HMA). In some embodiments, the diol contains at least one ether linkage. In some embodiments the diol is further reacted with at a second diacid, or a diester of said second diacid, wherein said second diacid is different from said first diacid. Prepolymers produced from such processes and articles formed therefrom are also described.
Abstract translation: 一种制备脂族聚酯预聚物的方法，其包括：单独或与其它反应物组合使二醇与至少一种第一二酸（或所述第一二酸的二酯）反应以产生脂族聚酯预聚物。 第一种二酸优选是反式-β-水凝胶酸（HMA）。 在一些实施方案中，二醇包含至少一个醚键。 在一些实施方案中，二醇进一步与所述第二二酸的第二二酸或二酯反应，其中所述第二二酸不同于所述第一二酸。 还描述了由这些方法制备的预聚物和由其形成的制品。
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82.发明授权Polyester based degradable materials and implantable biomedical articles formed therefrom 有权聚酯基可降解材料和由其形成的植入式生物医学制品公开(公告)号：US08013061B2
公开(公告)日：2011-09-06
申请号：US12281171
申请日：2007-03-05
Applicant: Valerie Ashby , David Olson
Inventor： Valerie Ashby , David Olson
CPC classification number: C08G63/52 , A61L27/18 , A61L31/06 , C08G63/672 , C08L67/04
Abstract: A method of making an aliphatic polyester prepolymer, comprising: reacting, alone or in combination with other reactants, a diol with at least a first diacid (or a diester of the first diacid) to produce an aliphatic polyester prepolymer. The first diacid is preferably a trans-beta-hydromuconic acid (HMA). In some embodiments, the diol contains at least one ether linkage. In some embodiments the diol is further reacted with at a second diacid, or a diester of the second diacid, wherein the second diacid is different from the first diacid. Prepolymers produced from such processes and articles formed therefrom are also described.
Abstract translation: 一种制备脂肪族聚酯预聚物的方法，其包括：单独或与其它反应物组合使二醇与至少第一二酸（或第一二酸的二酯）反应，以产生脂族聚酯预聚物。 第一种二酸优选是反式-β-水凝胶酸（HMA）。 在一些实施方案中，二醇包含至少一个醚键。 在一些实施方案中，二醇进一步与第二二酸或第二二酸的二酯反应，其中第二二酸不同于第一二酸。 还描述了由这些方法制备的预聚物和由其形成的制品。
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公开(公告)号：US20110135710A1
公开(公告)日：2011-06-09
申请号：US11628424
申请日：2005-06-01
Applicant: Gholamreza Sheikhnehjad , Mina Patel Sooch , Neal Goodwin , David Olson
Inventor： Gholamreza Sheikhnehjad , Mina Patel Sooch , Neal Goodwin , David Olson
CPC classification number: A61K31/7088 , A61K31/70 , A61K45/06 , A61K48/00 , A61K48/005 , C12N15/113 , C12N15/1135 , C12N2310/11 , C12N2310/3341
Abstract: The present invention relates to methods and compositions for the inhibition of gene expression. In particular, the present invention provides oligonucleotide-based therapeutics for the inhibition of oncogenes involved in cancers.
Abstract translation: 本发明涉及抑制基因表达的方法和组合物。 特别地，本发明提供了用于抑制参与癌症的癌基因的基于寡核苷酸的治疗剂。
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公开(公告)号：US07552681B1
公开(公告)日：2009-06-30
申请号：US11894628
申请日：2007-07-31
Applicant: Gerald Laib , David Olson , Daniel Jean , John Hendershot , Lawrence Fan , Michael Beggans , Ezra Chen
Inventor： Gerald Laib , David Olson , Daniel Jean , John Hendershot , Lawrence Fan , Michael Beggans , Ezra Chen
IPC: F42C15/34
CPC classification number: F42C15/184 , F42C15/005 , F42C15/20 , F42C15/21 , F42C15/24 , F42C15/34 , F42C15/40
Abstract: A MEMS fuze having a moveable slider with a microdetonator at an end for positioning adjacent an initiator. A setback activated lock and a spin activated lock prevent movement of the slider until respective axial and centrifugal acceleration levels have been achieved. Once these acceleration levels are achieved, the slider is moved by a V-beam shaped actuator arrangement to position the microdetonator relative to a secondary lead to start an explosive train in a munitions round.
Abstract translation: 具有可移动滑块的MEMS引信，其端部具有用于定位在起动器附近的微型密封剂。 挫折激活的锁和旋转启动的锁定防止滑块的移动，直到达到相应的轴向和离心加速度水平。 一旦达到这些加速度水平，滑块通过V形梁致动器装置移动，以使微型滴定器相对于次级引线定位，以便在弹药弹开始爆炸式火车。
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公开(公告)号：US07498315B2
公开(公告)日：2009-03-03
申请号：US10858145
申请日：2004-06-01
Applicant: Gholamreza Sheikhnehjad , Mina Patel Sooch , Neal Goodwin , David Olson
Inventor： Gholamreza Sheikhnehjad , Mina Patel Sooch , Neal Goodwin , David Olson
CPC classification number: C12N15/1135 , A61K31/70 , A61K48/00 , C12N2310/11 , C12N2310/3341
Abstract: The present invention relates to methods and compositions for the inhibition of gene expression. In particular, the present invention provides oligonucleotide-based therapeutics for the inhibition of oncogenes involved in cancers.
Abstract translation: 本发明涉及抑制基因表达的方法和组合物。 特别地，本发明提供了用于抑制参与癌症的癌基因的基于寡核苷酸的治疗剂。
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Patent Agency Ranking
公开(公告)号：US20080152700A1
公开(公告)日：2008-06-26
申请号：US10858094
申请日：2004-06-01
Applicant: Reza Sheikhnejad , Mina Patel Sooch , Neal Goodwin , David Olson
Inventor： Reza Sheikhnejad , Mina Patel Sooch , Neal Goodwin , David Olson
CPC classification number: C12N15/1135 , A61K31/70 , A61K48/00 , C12N2310/11 , C12N2310/3341
Abstract: The present invention relates to methods and compositions for the inhibition of gene expression. In particular, the present invention provides oligonucleotide-based therapeutics for the inhibition of oncogenes involved in cancers.
Abstract translation: 本发明涉及抑制基因表达的方法和组合物。 特别地，本发明提供了用于抑制参与癌症的癌基因的基于寡核苷酸的治疗剂。
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87.发明申请公开(公告)号：US20080075925A1
公开(公告)日：2008-03-27
申请号：US11950798
申请日：2007-12-05
Applicant: Clinton Jones , Brant Kolb , David Olson , Emily Goenner
Inventor： Clinton Jones , Brant Kolb , David Olson , Emily Goenner
CPC classification number: G02B6/0053 , B82Y20/00 , C08G18/672 , C08K3/22 , C08K9/06 , C08L75/16 , G02B5/045 , G02B5/124 , G02B6/0056 , G02B2207/101 , Y10S428/913 , Y10S977/778 , Y10S977/932 , Y10T428/10 , Y10T428/1036 , Y10T428/1068 , Y10T428/1082 , Y10T428/2457 , Y10T428/259 , Y10T428/31551 , Y10T428/31573 , Y10T428/31598 , Y10T428/31855 , C08G18/42
Abstract: Presently described are microstructured articles such as a brightness enhancing film or optical turning film. The microstructured articles comprise a brightness enhancing polymerized structure comprising the reaction product of a composition comprising an organic component having at least one oligomeric urethane (meth)acrylate and surface modified silica nanoparticles.
Abstract translation: 目前描述的是微结构物品，例如亮度增强膜或光学转向膜。 微结构化制品包含亮度增强聚合结构，其包含包含至少一种低聚氨基甲酸酯（甲基）丙烯酸酯和表面改性二氧化硅纳米颗粒的有机组分的组合物的反应产物。
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88.发明申请Medical device programmer with selective disablement of display during telemetry 审中-公开在遥测中具有选择性禁用显示功能的医疗设备编程器公开(公告)号：US20070288068A1
公开(公告)日：2007-12-13
申请号：US11890592
申请日：2007-08-07
Applicant: Alex Toy , Steve Nelson , John Forsberg , Mark Schommer , David Olson , William Phillips , Carles Lewis
Inventor： Alex Toy , Steve Nelson , John Forsberg , Mark Schommer , David Olson , William Phillips , Carles Lewis
IPC: A61N1/02
CPC classification number: A61N1/37229 , A61N1/37235 , A61N1/37247 , Y10S128/903
Abstract: In general, the invention is directed to a patient programmer for an implantable medical device. The patient programmer may include one or more of a variety of features that may enhance performance, support mobility and compactness, or promote patient convenience.
Abstract translation: 通常，本发明涉及可植入医疗装置的患者编程器。 患者程序员可以包括可以增强性能，支持移动性和紧凑性或促进患者便利性的多种特征中的一种或多种。
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公开(公告)号：US20070282259A1
公开(公告)日：2007-12-06
申请号：US11754759
申请日：2007-05-29
Applicant: Mary Morris , Timothy Laske , Kenneth Heruth , Michael Ujhelyi , Jesus Casas , David Olson
Inventor： Mary Morris , Timothy Laske , Kenneth Heruth , Michael Ujhelyi , Jesus Casas , David Olson
IPC: A61M25/14
CPC classification number: A61M25/0075
Abstract: A catheter body includes an exit port over which a pressure responsive sleeve is formed that allows material to exit a lumen of the catheter body at a given pressure. In one embodiment, a surface of the sleeve is approximately flush with a surface of the catheter body.
Abstract translation: 导管主体包括出口，在该出口处形成压力响应套筒，其允许材料在给定压力下离开导管体的内腔。 在一个实施例中，套筒的表面与导管主体的表面大致齐平。
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公开(公告)号：US20070264517A1
公开(公告)日：2007-11-15
申请号：US11778757
申请日：2007-07-17
Applicant: DAVID OLSON , Bettie Fong , Ying-Yuh Lu , Cheryl Moore , Todd Williams
Inventor： DAVID OLSON , Bettie Fong , Ying-Yuh Lu , Cheryl Moore , Todd Williams
IPC: C08F220/10
CPC classification number: C08F220/18 , C08F220/06 , C08F220/30 , C08F220/38 , C09J7/385 , Y10T428/31938
Abstract: The present invention provides pressure-sensitive adhesives having a refractive index of at least 1.48. The pressure-sensitive adhesives comprise at least one monomer containing a substituted or an unsubstituted aromatic moiety.
Abstract translation: 本发明提供折射率至少为1.48的压敏粘合剂。 压敏粘合剂包含至少一种含有取代或未取代的芳族部分的单体。
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