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    Router and rapid response network
    81.
    发明授权
    Router and rapid response network 有权
    路由器和快速响应网络

    公开(公告)号：US08761000B2

    公开(公告)日：2014-06-24

    申请号：US13306970

    申请日：2011-11-29

    Applicant: Frank J. Knox

    Inventor： Frank J. Knox

    IPC: H04W76/04 ,  H04W28/08 ,  H04W48/00 ,  H04W88/16

    CPC classification number: H04W36/0022 ,  H04W24/04 ,  H04W24/08 ,  H04W28/08 ,  H04W36/22 ,  H04W48/17 ,  H04W88/16

    Abstract: A router includes a plurality of wireless network carrier cards, each of the network carrier cards adapted for use with one of a like plurality of different carrier networks, means for determining which of the plurality of network carrier cards provides a suitable connection to a carrier network and means for selecting one or more suitable connections to one or more carrier networks and for connecting the EVDO router to the carrier network through a particular one of the plurality of network carrier cards and a load balancing processor for load balancing between a plurality of different backbone networks and wherein the load balancing processor directs traffic among multiple networks to provide a desired throughput. In one embodiment, the router is provided as an evolution-data optimized (EVDO) wireless router.

    Abstract translation: 路由器包括多个无线网络运营商卡，每个网络运营商卡适合与多个不同的运营商网络中的一个一起使用，用于确定多个网络运营商卡中的哪一个提供与运营商网络的合适连接的装置 以及用于选择与一个或多个运营商网络的一个或多个合适连接以及用于通过所述多个网络运营商卡中的特定一个将所述EVDO路由器连接到所述运营商网络的装置，以及用于在多个不同主干之间进行负载平衡的负载平衡处理器 网络，并且其中所述负载平衡处理器引导多个网络之间的业务以提供期望的吞吐量。 在一个实施例中，路由器被提供为演进数据优化（EVDO）无线路由器。

    Modulation of TIM receptor activity in combination with cytoreductive therapy
    82.
    发明授权
    Modulation of TIM receptor activity in combination with cytoreductive therapy 有权
    调节TIM受体活性与细胞减灭疗法联合应用

    公开(公告)号：US08709412B2

    公开(公告)日：2014-04-29

    申请号：US13176651

    申请日：2011-07-05

    Applicant: Jennifer Jones ,  Rosemarie Dekruyff ,  Dale T. Umetsu ,  Gordon J. Freeman ,  Susan Jane Knox

    Inventor： Jennifer Jones ,  Rosemarie Dekruyff ,  Dale T. Umetsu ,  Gordon J. Freeman ,  Susan Jane Knox

    IPC: A61K39/395

    CPC classification number: C07K16/30 ,  A61K39/0011 ,  C07K14/70503 ,  C07K2317/75

    Abstract: A genetic locus and corresponding family of proteins associated with regulation of immune function and cell survival are provided. These genes encode cell surface molecules with conserved IgV and mucin domains. The locus comprising the TIM family is genetically associated with immune dysfunction, including asthma. Furthermore, the TIM gene family is located within a region of human chromosome 5 that is commonly deleted in malignancies and myelodysplastic syndrome. Polymorphisms in the gene sequences are associated with the development of airway hyperreactivity and allergic inflammation, and T cell production of IL-4 and IL-13. The proteins include the human hepatitis A cellular receptor, hHAVcr-1.

    Abstract translation: 提供了与调节免疫功能和细胞存活相关的遗传基因座和相应的蛋白质家族。 这些基因编码具有保守IgV和粘蛋白结构域的细胞表面分子。 包含TIM家族的基因座与遗传上与免疫功能障碍有关，包括哮喘。 此外，TIM基因家族位于人类染色体5的区域，通常在恶性肿瘤和骨髓增生异常综合征中缺失。 基因序列中的多态性与气道高反应性和过敏性炎症的发生以及IL-4和IL-13的T细胞产生有关。 蛋白质包括人类甲型肝炎细胞受体hHAVcr-1。

    MECHANISM FOR FACILITATING REAL-TIME STREAMING, FILTERING AND ROUTING OF DATA
    84.
    发明申请
    MECHANISM FOR FACILITATING REAL-TIME STREAMING, FILTERING AND ROUTING OF DATA 审中-公开
    促进实时流动，数据过滤和路由的机制

    公开(公告)号：US20140040433A1

    公开(公告)日：2014-02-06

    申请号：US13954359

    申请日：2013-07-30

    Applicant: DANIEL DALE RUSSELL, JR. ,  Brian C. Knox

    Inventor： DANIEL DALE RUSSELL, JR. ,  Brian C. Knox

    IPC: H04L29/06

    CPC classification number: H04L65/60 ,  H04L65/605 ,  H04N21/23418 ,  H04N21/2343 ,  H04N21/237 ,  H04N21/2665 ,  H04N21/4402 ,  H04N21/4622

    Abstract: In accordance with embodiments, there are provided mechanisms for facilitating real-time streaming, filtering and routing of data according to one embodiment. In one embodiment and by way of example, a method includes receiving, at a computing device, one or more data streams from one or more data sources, transforming, in real-time, the one or more data streams into one or more normalized data streams. The transforming includes performing ingestion of the one or more data streams. The method may further include filtering, in real-time, the one or more normalized data streams, and routing the one or more filtered data streams as real-time output to one or more data systems.

    Abstract translation: 根据实施例，根据一个实施例，提供了用于促进数据的实时流，过滤和路由的机制。 在一个实施例中并且作为示例，一种方法包括在计算设备处接收来自一个或多个数据源的一个或多个数据流，实时地将一个或多个数据流变换成一个或多个归一化数据 流。 转化包括执行摄取一个或多个数据流。 该方法还可以包括实时地过滤一个或多个归一化数据流，并将一个或多个经过滤波的数据流作为实时输出路由到一个或多个数据系统。

    Actuator Assembly with Preloaded Ball Screws
    89.
    发明申请
    Actuator Assembly with Preloaded Ball Screws 有权
    带预滚球螺杆的执行机构组件

    公开(公告)号：US20130249464A1

    公开(公告)日：2013-09-26

    申请号：US13427382

    申请日：2012-03-22

    Applicant: Lawrence D. Knox ,  Dariusz A. Bushko ,  Marco Giovanardi

    Inventor： Lawrence D. Knox ,  Dariusz A. Bushko ,  Marco Giovanardi

    IPC: G05B11/32 ,  F16H25/12

    CPC classification number: B60G17/0157 ,  B60G17/018 ,  B60G2202/42 ,  B60G2202/44 ,  B60G2204/419 ,  B60G2300/60 ,  B60G2600/182 ,  B60G2600/44 ,  B60G2800/916 ,  F16F2232/04 ,  F16H25/2204 ,  F16H25/2209 ,  F16H2057/122 ,  H02K7/06 ,  H02K16/00

    Abstract: An actuator assembly includes a first motor having a first transmission mechanism, a second motor having a second transmission mechanism, and a drive shaft operatively coupled to the first transmission mechanism of the first motor and the second transmission mechanism of the second motor. The actuator assembly includes a torque application system disposed in operative communication with the first motor and the second motor, the torque application system configured to direct an application of a translation torque and a preload torque between the first motor and the first transmission mechanism and between the second motor and the second transmission mechanism.

    Abstract translation: 致动器组件包括具有第一传动机构的第一电动机，具有第二传动机构的第二电动机和可操作地联接到第一电动机的第一传动机构和第二电动机的第二传动机构的驱动轴。 所述致动器组件包括设置成与所述第一电动机和所述第二电动机可操作地连通的转矩施加系统，所述转矩施加系统被配置为引导所述第一电动机和所述第一变速机构之间以及所述第一变速机构之间的平移转矩和预紧力矩的施加 第二马达和第二传动机构。

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