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公开(公告)号：US20210324038A1
公开(公告)日：2021-10-21
申请号：US17255629
申请日：2019-06-27
Inventor： Sang Taek JUNG , Ji Yeon HA
IPC: C07K14/705 , C12N15/10
Abstract: A PD-L1 mutant having improved binding affinity for PD-1 is disclosed. A method for preparing the PD-L1 variant and a method for screening the PD-L1 variant are also disclosed. The PD-L1 variant produced by substituting some amino acids in the sequence of wild-type PD-L1 with other optimal amino acids, achieving greatly improved affinity for PD-1. In addition, the possibility of immunogenicity can be reduced by the smallest possible number of the mutation sites.
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公开(公告)号：US20210299627A1
公开(公告)日：2021-09-30
申请号：US17034903
申请日：2020-09-28
Applicant: HYUNDAI MOTOR COMPANY , KIA MOTORS CORPORATION , Kookmin University Industry Academy Cooperation Foundation
Inventor： Dong Hoon NAM , Kyung Moon LEE , Hoon Mo PARK , Young-Jin CHO , Byeong Soo SHIN , Hee Joon LEE , Seon Jeong HUH
Abstract: A dehydrogenation chemical reactor includes: a housing; a catalyst part made of a thermally conductive material and disposed in the housing, where the catalyst part has a panel shape, and a catalyst is coated on a surface of the catalyst part to separate hydrogen from an organic hydrogen carrier; a heat transfer pipe which is installed to contact the catalyst part, and conducts latent heat to the catalyst part while pressurized and saturated fluid is supplied therein; and an organic hydrogen carrier line which is connected to the housing to form a passage in which the organic hydrogen carrier is introduced into the housing, contacts the catalyst part to separate hydrogen, and then is discharged.
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公开(公告)号：US11009392B2
公开(公告)日：2021-05-18
申请号：US16511065
申请日：2019-07-15
Inventor： Young Rag Do , Ji Hye Oh
Abstract: The present disclosure provides a circadian illuminance measuring apparatus including: a circadian lambda filter configured to pass external light according to a circadian sensitivity curve; a light sensor configured to sense the external light has passed through the circadian lambda filter, convert the external light into an analog signal, and output the analog signal; and a circadian illuminance calculator configured to convert the analog signal into a digital signal to calculate circadian illuminance of the external light.
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84.发明申请公开(公告)号：US20210139655A1
公开(公告)日：2021-05-13
申请号：US17255422
申请日：2019-05-09
Inventor： Moon Hee SUNG , Misun KWAK , Sang Joon PARK
Abstract: The present invention relates to a method of preparing a poly-γ-glutamic acid hydrogel using ultraviolet ray and to a use of the poly-γ-glutamic acid hydrogel prepared by the method, and the method of preparing poly-γ-glutamic acid hydrogel using ultraviolet irradiation according to the present invention solved the problem of microbial contamination in the poly-γ-glutamic acid solution, and produced poly-γ-glutamic acid hydrogel in high yield by only a simple treatment process, and as it was confirmed that the poly-γ-glutamic acid hydrogel has improved storage stability in a solution, the poly-gamma-glutamic acid hydrogel prepared by the method of preparing the same of the present invention can be provided as a tissue engineering scaffold, artificial organs and bio-ink for 3D printing.
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公开(公告)号：US10964876B2
公开(公告)日：2021-03-30
申请号：US16038941
申请日：2018-07-18
Applicant: Hyundai Motor Company , Kia Motors Corporation , Kookmin University Industry Academy Cooperation Foundation
Inventor： Eun Yeong Lee , Mi Yeon Song , Sang Hak Kim , Hyun Jung Lee , Hyun Woo Bark , Young Hoe Kim
Abstract: An integrated flexible thermoelectric device includes p-type carbon nanoparticle regions and n-type carbon nanoparticle regions which are alternately and continuously connected to each other. In particular, the p-type carbon nanoparticle regions and the n-type carbon nanoparticle regions are formed on the one carbon nanoparticle paper.
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Patent Agency Ranking
公开(公告)号：US10918625B2
公开(公告)日：2021-02-16
申请号：US16686940
申请日：2019-11-18
Inventor： Sangtaek Oh
IPC: A61K31/423 , A61K31/122 , A61K31/136 , A23L33/10 , A61P27/02 , A61K31/145 , A61K31/196 , A61K31/235 , A61K31/4184 , A61K9/00 , A61K31/015 , A61K9/06
Abstract: The present disclosure relates to a novel use of a sesquiterpene derivative, more particularly to a composition for preventing, improving or treating macular degeneration or macular edema caused by vascular leakage in the eye, the composition containing a sesquiterpene derivative compound represented by Chemical Formula 1 of the present disclosure or a pharmaceutically acceptable salt thereof as an active ingredient. Whereas the intraocular disease-related treating agents available in the market should be injected directly into the vitreous cavity, thus causing pain and side effects, the sesquiterpene derivative compound of the present disclosure is delivered to the target tissue (eye) via different administration routes (oral, intraperitoneal, etc.) other than the intravitreal route. Accordingly, the sesquiterpene derivative compound provides excellent therapeutic effect without being restricted by the administration routes.
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公开(公告)号：US10742318B2
公开(公告)日：2020-08-11
申请号：US16069822
申请日：2016-11-28
Inventor： Yeong Min Jang , Van Trang Nguyen , Chang Hyun Hong
IPC: H04B10/116 , H04B10/556 , H04B10/67 , H04N7/22
Abstract: An optical wireless communication apparatus includes: a modulator for generating a reference signal including periodically repeating binary zeros and ones, receiving an input of a first binary data signal, and outputting a second binary data signal, wherein the second binary data signal has the same frequency as the reference signal, and has the same phase as the reference signal when the first binary data signal comprises binary zeros and has an opposite phase to the reference signal when the first binary data signal comprises binary ones, or has the same phase as the reference signal when the first binary data signal comprises binary ones and has an opposite phase to the reference signal when the first binary data signal comprises binary zeros, and a transmitter for turning a first light source on or off according to the reference signal, and turning a second light source on or off according to the second binary data signal.
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公开(公告)号：US20200252131A1
公开(公告)日：2020-08-06
申请号：US16494687
申请日：2017-12-31
Inventor： Yeong Min JANG , Van Trang NGUYEN
IPC: H04B10/516 , H04B10/67 , H04B10/50
Abstract: An optical wireless transmission device according to an embodiment of the present invention comprises: a modulation unit for receiving input of a first input signal and outputting a first output signal; and a light source control unit for controlling a first light source in accordance with the first output signal. The first output signal repeats “0” and “1” in a first phase during clock time if a binary value of the first input signal is 0, and repeats “0” and “1” in a phase opposite from the first phase during the clock time if a binary value of the first input signal is 1.
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公开(公告)号：US10323306B2
公开(公告)日：2019-06-18
申请号：US14740296
申请日：2015-06-16
Inventor： Hyunjoo Choi , Jonggyu Jeon , Seungjin Nam
Abstract: An austenitic steel matrix-nanoparticle composite and a producing method thereof are provided. The composite includes: an austenitic steel matrix that includes an alloying element; and a nanoparticle that grows in situ in the matrix and that is formed in the matrix. The nanoparticle grows from the alloying element included in the austenitic steel matrix. The method includes: preparing an austenitic steel matrix including an alloying element; and heating the austenitic steel matrix. In the method, the nanoparticle grows in situ in the matrix from the alloying element which is solid-dissolved in the austenitic steel matrix by the heating.
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公开(公告)号：US10239770B2
公开(公告)日：2019-03-26
申请号：US15488817
申请日：2017-04-17
Inventor： Sang-Ho Lee , Yong-Jun Choi , Jin-Sik Sohn , Yong-Hyun Shin , Ji-Hyeok Choi
Abstract: A multi-stage submerged membrane distillation water treatment apparatus including: a plurality of raw water tanks arranged in multiple stages ranging from a first stage to an n-th stage and storing raw water, the raw water flowing sequentially from the first stage to the n-th stage; membrane distillation (MD) modules submerged in the respective raw water tanks and discharging a portion of the raw water as vapor; heat exchangers submerged in the respective raw water tanks and maintaining the raw water at a predetermined temperature by performing heat exchange between the raw water and vapor supplied from the respective previous-stage MD modules; a vapor generator generating and supplying high-temperature vapor to the first-stage heat exchanger; a condenser condensing vapor supplied by the n-th-stage MD module; and a raw water feeder feeding low-temperature raw water to the first-stage raw water tank via the condenser.
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