公开(公告)号：US20090061897A1

公开(公告)日：2009-03-05

申请号：US12138087

申请日：2008-06-12

Applicant: Patrick Hamilton ,  Michael Barker ,  Wilfred Mueller ,  Francisco Litorco ,  Allan L.A. Scribner

Inventor： Patrick Hamilton ,  Michael Barker ,  Wilfred Mueller ,  Francisco Litorco ,  Allan L.A. Scribner

IPC: H04W24/00 ,  G05B19/00

CPC classification number: G08G9/00 ,  G06Q10/08 ,  G08G1/20 ,  G08G5/0082

Abstract: The invention describes a tracking, security and status monitoring system (TSS) and modular tracking and security device (MTSD). The tracking and security system includes at least one MTSD adapted for containment within a shipment within a vehicle and for operative communication with a global navigation satellite system (GNSS) (such as the global positioning system (GPS)), cellular networks and a monitoring system. In various embodiments, the MTSD is modular allowing for different sensor systems to be configured to the system, is operative to optimize power consumption and network data usage in the absence of a security event or inquiry from the monitoring system and/or allows the MTSD to recognize when it is within an airborne aircraft to comply with aviation regulations with respect to the operation of RF devices within aircraft. In addition, the system, by using both GNSS and cellular technology (ie. assisted GPS) is effective in being able to determine the real time position of a shipment from a greater number of positions and from deeper within shipment containers or vehicles.

Abstract translation: 本发明描述了跟踪，安全和状态监测系统（TSS）和模块化跟踪和安全设备（MTSD）。 跟踪和安全系统包括至少一个适于在车辆内的货物内容纳的MTSD，以及用于与全球导航卫星系统（GNSS）（例如全球定位系统（GPS）），蜂窝网络和监视系统的操作性通信 。 在各种实施例中，MTSD是模块化的，允许将不同的传感器系统配置到系统，在不存在来自监视系统的安全事件或查询的情况下，可操作以优化功率消耗和网络数据使用，和/或允许MTSD 识别何时在机载飞机内符合关于飞机内射频设备操作的航空条例。 此外，通过使用GNSS和蜂窝技术（即辅助GPS），该系统能够从更大数量的位置和更深的装运集装箱或车辆中确定货物的实时位置是有效的。

公开(公告)号：US20080243220A1

公开(公告)日：2008-10-02

申请号：US11692772

申请日：2007-03-28

Applicant: John Michael Barker

Inventor： John Michael Barker

IPC: A61N1/02

CPC classification number: A61N1/0558 ,  A61N1/0573 ,  A61N2001/058

Abstract: Disclosed is a lead anchor comprising a body made of an elastomeric material and defining a first opening and a second opening through which a lead can pass, one or more fasteners disposed within the body, with the ends of the fasteners protruding from the body, wherein the ends are configured and arranged to be clamped down to secure a lead passing through the body.

Abstract translation: 公开了一种引导锚，其包括由弹性体材料制成的主体并且限定了引线可以穿过的第一开口和第二开口，设置在主体内的一个或多个紧固件，紧固件的端部从主体突出，其中 端部被构造和布置成被夹紧以固定穿过身体的引线。

公开(公告)号：US20070161673A1

公开(公告)日：2007-07-12

申请号：US10587989

申请日：2005-01-27

Applicant: Michael Barker ,  Julie Hamblin ,  Katherine Jones ,  Vipulkumar Patel ,  Stephen Swanson ,  Ann Walker

Inventor： Michael Barker ,  Julie Hamblin ,  Katherine Jones ,  Vipulkumar Patel ,  Stephen Swanson ,  Ann Walker

IPC: A61K31/4745 ,  C07D471/02

CPC classification number: C07D471/04

Abstract: Compounds of formula (I): are inhibitors of p38 kinase and are useful in the treatment of conditions or disease states mediated by p38 kinase activity or mediated by cytokines produced by the activity of p38.

Abstract translation: 式（I）化合物：p38激酶的抑制剂，可用于治疗由p38激酶活性介导的或由p38活性产生的细胞因子介导的病状或疾病状态。

公开(公告)号：US20070142373A1

公开(公告)日：2007-06-21

申请号：US10557079

申请日：2004-05-19

Applicant: Ian Baldwin ,  Michael Barker ,  Anthony Dean ,  Colin Eldred ,  Brian Evans ,  Sharon Gough ,  Stephen Guntrip ,  Julie Hamblin ,  Stuart Holman ,  Paul Jones ,  Mika Lindvall ,  Christopher Lunniss ,  Tracy Redfern ,  Alison Redgrave ,  John Robinson ,  Michael Woodrow

Inventor： Ian Baldwin ,  Michael Barker ,  Anthony Dean ,  Colin Eldred ,  Brian Evans ,  Sharon Gough ,  Stephen Guntrip ,  Julie Hamblin ,  Stuart Holman ,  Paul Jones ,  Mika Lindvall ,  Christopher Lunniss ,  Tracy Redfern ,  Alison Redgrave ,  John Robinson ,  Michael Woodrow

IPC: A61K31/5377 ,  A61K31/496 ,  A61K31/4709 ,  C07D413/02 ,  C07D403/02 ,  C07D401/02

CPC classification number: C07D401/12 ,  C07D215/54 ,  C07D401/14 ,  C07D405/12 ,  C07D405/14 ,  C07D409/12 ,  C07D413/12 ,  C07D413/14 ,  C07D417/12 ,  C07D417/14 ,  C07D453/02

Abstract: There are provided according to the invention novel compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R19, R20, and R34 are as described in the specification, processes for preparing them, formulations containing them and their use in therapy for the treatment of inflammatory diseases.

Abstract translation: 根据本发明提供新的式（I）化合物或其药学上可接受的盐，其中R 1，R 2，R 19，R 20和R 34如说明书中所述，其制备方法，含有 他们及其在治疗炎症性疾病中的应用。