公开(公告)号：US20120121597A1

公开(公告)日：2012-05-17

申请号：US13294652

申请日：2011-11-11

Applicant: David Ho ,  Yaoxing Huang ,  Craig Pace ,  Ruijiang Song ,  Qing Fang

Inventor： David Ho ,  Yaoxing Huang ,  Craig Pace ,  Ruijiang Song ,  Qing Fang

IPC: A61K39/42 ,  A61P31/18 ,  C07K16/46

CPC classification number: C07K16/2812 ,  C07K16/1063 ,  C07K2317/24 ,  C07K2317/31 ,  C07K2317/35 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/622 ,  C07K2317/64 ,  C07K2317/76 ,  C07K2317/92 ,  C07K2319/00

Abstract: Disclosed herein are fusion antibodies created to provide both an antigen-binding site that targets the CD4 receptor and an antigen-binding site that targets the HIV envelope. The fusion antibodies disclosed herein provide improved potency and breadth against HIV as compared to monospecific antibodies, and additionally provide high barrier against viral resistance. Also disclosed are pharmaceutical formulations and therapeutic methods utilizing such fusion proteins.

Abstract translation: 本文公开了产生以提供靶向CD4受体的抗原结合位点和靶向HIV包膜的抗原结合位点的融合抗体。 与单特异性抗体相比，本文公开的融合抗体提供了针对HIV的改进的效力和广度，并且另外提供了抗病毒抗性的高屏障。 还公开了使用这种融合蛋白的药物制剂和治疗方法。

公开(公告)号：US07781859B2

公开(公告)日：2010-08-24

申请号：US12054224

申请日：2008-03-24

Applicant: Puo-Yu Chiang ,  Tsai Chun Lin ,  Chih-Wen (Albert) Yao ,  David Ho

Inventor： Puo-Yu Chiang ,  Tsai Chun Lin ,  Chih-Wen (Albert) Yao ,  David Ho

IPC: H01L29/47

CPC classification number: H01L29/872 ,  H01L29/0623 ,  H01L29/0649

Abstract: An integrated circuit structure includes a semiconductor substrate; a well region of a first conductivity type over the semiconductor substrate; a metal-containing layer on the well region, wherein the metal-containing layer and the well region form a Schottky barrier; an isolation region encircling the metal-containing layer; and a deep-well region of a second conductivity type opposite the first conductivity type under the metal-containing layer. The deep-well region has at least a portion vertically overlapping a portion of the metal-containing layer. The deep-well region is vertically spaced apart from the isolation region and the metal-containing layer by the well region.

Abstract translation: 集成电路结构包括半导体衬底; 半导体衬底上的第一导电类型的阱区; 在所述阱区上的含金属层，其中所述含金属层和所述阱区形成肖特基势垒; 围绕所述含金属层的隔离区域; 以及在金属含有层下面与第一导电类型相反的第二导电类型的深阱区域。 深井区具有至少一部分与含金属层的一部分垂直重叠的部分。 深阱区域与隔离区域垂直间隔开，并且阱区域与金属含量层垂直间隔开。

公开(公告)号：US20090236679A1

公开(公告)日：2009-09-24

申请号：US12054224

申请日：2008-03-24

Applicant: Puo-Yu Chiang ,  Tsai Chun Lin ,  Chih-Wen Albert Yao ,  David Ho

Inventor： Puo-Yu Chiang ,  Tsai Chun Lin ,  Chih-Wen Albert Yao ,  David Ho

IPC: H01L29/872

CPC classification number: H01L29/872 ,  H01L29/0623 ,  H01L29/0649

Abstract: An integrated circuit structure includes a semiconductor substrate; a well region of a first conductivity type over the semiconductor substrate; a metal-containing layer on the well region, wherein the metal-containing layer and the well region form a Schottky barrier; an isolation region encircling the metal-containing layer; and a deep-well region of a second conductivity type opposite the first conductivity type under the metal-containing layer. The deep-well region has at least a portion vertically overlapping a portion of the metal-containing layer. The deep-well region is vertically spaced apart from the isolation region and the metal-containing layer by the well region.

Abstract translation: 集成电路结构包括半导体衬底; 半导体衬底上的第一导电类型的阱区; 在所述阱区上的含金属层，其中所述含金属层和所述阱区形成肖特基势垒; 围绕所述含金属层的隔离区域; 以及在金属含有层下面与第一导电类型相反的第二导电类型的深阱区域。 深井区具有至少一部分与含金属层的一部分垂直重叠的部分。 深阱区域与隔离区域垂直间隔开，并且阱区域由金属含有层垂直间隔开。

公开(公告)号：US20080185281A1

公开(公告)日：2008-08-07

申请号：US11808405

申请日：2007-06-08

Applicant: Ching-Sung Chang ,  David Ho ,  Po-Cheng Chen ,  Sea-Weng Young

Inventor： Ching-Sung Chang ,  David Ho ,  Po-Cheng Chen ,  Sea-Weng Young

IPC: H01H9/26 ,  H01H1/10

CPC classification number: H01H13/85 ,  G06F3/0202 ,  H01H2215/036 ,  H01H2221/09 ,  H01H2225/03 ,  H01H2229/038 ,  H01H2239/074

Abstract: A touch input device constructed in a carrier electronic apparatus comprises a touch panel, a flexible printed circuit board, a rubber cushion and a plurality of metal domes. The touch panel performs as a touch input interface of the apparatus to a user, the flexible printed circuit board is shaped into a C form so as to present an upper flexible printed circuit board and a lower flexible printed circuit board, the rubber cushion is disposed between the upper flexible printed circuit board and the lower flexible printed circuit board, and the plurality of metal domes is disposed between the rubber cushion and the lower flexible printed circuit board. Each of the metal domes is in a position to account for a specific function key.

Abstract translation: 构造在载体电子装置中的触摸输入装置包括触摸面板，柔性印刷电路板，橡胶垫和多个金属圆顶。 触摸面板作为用户的设备的触摸输入接口，将柔性印刷电路板成形为C形，以呈现上部柔性印刷电路板和下部柔性印刷电路板，橡胶垫被设置 在上柔性印刷电路板和下柔性印刷电路板之间，并且多个金属圆顶布置在橡胶垫和下柔性印刷电路板之间。 每个金属圆顶都可以解决特定的功能键。

公开(公告)号：US20070260789A1

公开(公告)日：2007-11-08

申请号：US11637736

申请日：2006-12-13

Applicant: David Ho ,  Jing-Xin Liang

Inventor： David Ho ,  Jing-Xin Liang

IPC: G06F13/00

CPC classification number: G06F13/4273

Abstract: An interface transmission structure between modules and its method comprise a central processor installed in an electronic device, a first pin and a second pin installed in the central processor and coupled respectively to a third pin and a fourth pin of at least one module. The central processor is able to receive different voltage amplitudes and to set a plurality of potential levels. The first and second pins respectively output a different output signal to each module according to each potential level, and the output signals are combined into a plurality of command messages, data messages, and status messages. At least one module is also able to receive different voltage amplitudes and to output another output signal according to the different potential levels via the third and fourth pins, and the other output signals are combined into another plurality of data messages and status messages, in order to substitute the conventional data lines, address lines, and control lines and expedite the processing of each message.

Abstract translation: 模块之间的接口传输结构及其方法包括安装在电子设备中的中央处理器，安装在中央处理器中的第一引脚和第二引脚，并分别耦合到至少一个模块的第三引脚和第四引脚。 中央处理器能够接收不同的电压幅度并设置多个电位电平。 第一和第二引脚根据每个电位电平分别向每个模块输出不同的输出信号，并将输出信号组合成多个命令消息，数据消息和状态消息。 至少一个模块还能够接收不同的电压幅度，并且经由第三和第四引脚根据不同的电位电平输出另一个输出信号，并且其它输出信号按顺序组合成另一个多个数据消息和状态消息 替代传统的数据线，地址线和控制线，并加快每条消息的处理。

公开(公告)号：US20070238871A1

公开(公告)日：2007-10-11

申请号：US11735313

申请日：2007-04-13

Applicant: Moriya Tsuji ,  David Ho ,  Chi-Huey Wong ,  Douglass Wu ,  Masakazu Fujio

Inventor： Moriya Tsuji ,  David Ho ,  Chi-Huey Wong ,  Douglass Wu ,  Masakazu Fujio

IPC: C08B37/00 ,  C07D315/00

CPC classification number: C07H15/04 ,  A61K39/39 ,  C07H15/10

Abstract: This invention relates to immunogenic compounds which serve as ligands for NKT (natural killer T) cells and to methods of use thereof in modulating immune responses.

Abstract translation: 本发明涉及用作NKT（天然杀伤T）细胞的配体的免疫原性化合物及其在调节免疫应答中的应用。

公开(公告)号：US20070064961A1

公开(公告)日：2007-03-22

申请号：US11523649

申请日：2006-09-20

Applicant: Ying-Feng Jiang ,  David Ho

Inventor： Ying-Feng Jiang ,  David Ho

IPC: H03G3/00 ,  H03G9/00

CPC classification number: H03G3/002 ,  H03G3/3005 ,  H03G3/3089

Abstract: An audio control system includes: a receiving unit for receiving an analog signal, a memory unit for storing a reference table for recording a predetermined signal data, a control unit for converting the analog signal into a digital signal and conducting a comparison of the digital signal with respect to the reference so as to adjust a corresponding gain of the digital signal according to said predetermined signal data, thereby generating a voice signal according to said corresponding gain. An output unit is used for outputting the voice signal.

Abstract translation: 音频控制系统包括：用于接收模拟信号的接收单元，用于存储用于记录预定信号数据的参考表的存储单元，用于将模拟信号转换成数字信号并进行数字信号比较的控制单元 相对于参考，以便根据所述预定信号数据调整数字信号的相应增益，从而根据所述对应的增益生成语音信号。 输出单元用于输出语音信号。

公开(公告)号：US20070019248A1

公开(公告)日：2007-01-25

申请号：US11490099

申请日：2006-07-21

Applicant: David Ho ,  Yong-Ping Zheng

Inventor： David Ho ,  Yong-Ping Zheng

IPC: H04N1/40

CPC classification number: G06K9/00449

Abstract: In a method for collecting information of business cards in a mobile communication device including an image capturing unit, a recognition software and a page layout database having a plurality of page layout formats. The image capturing unit captures and converts a traditional business card into an image of a business card, and the recognition software optimizes the image to facilitate recognizing the image. The mobile communication device uses the recognition software and page layout database to analyze and recognize the image of business card according to the page layout database to choose a page layout format from the page layout database that matches the image of business card and, if the page layout format exists, identifies a character from the image of business card, and inputs and stores the character into a business card database in the mobile communication device according to the page layout format, so as to complete the data collection for the traditional business card.

Abstract translation: 一种用于在包括图像捕获单元，识别软件和具有多个页面布局格式的页面布局数据库的移动通信设备中收集名片的信息的方法。 图像捕获单元捕获并将传统名片转换成商务卡的图像，并且识别软件优化图像以便于识别图像。 移动通信设备使用识别软件和页面布局数据库，根据页面布局数据库分析和识别名片图像，从与名片图像相匹配的页面布局数据库中选择页面布局格式，如果页面 布局格式存在，从名片图像中识别字符，并根据页面布局格式将该字符输入并存储到移动通信设备中的名片数据库中，以完成传统名片的数据收集。

公开(公告)号：US20070018981A1

公开(公告)日：2007-01-25

申请号：US11492146

申请日：2006-07-25

Applicant: Zheng Zhang ,  David Ho

Inventor： Zheng Zhang ,  David Ho

IPC: G06T15/20

CPC classification number: G09G5/246 ,  G06F1/1626 ,  G06F1/1637 ,  G06F1/1647 ,  G06F1/1694 ,  G09G3/001 ,  G09G3/004 ,  H04M1/22 ,  H04M1/72544 ,  H04M2250/12

Abstract: An electronic display apparatus comprises a lighting unit, a displacement detecting unit, a storage unit and a data processing unit. The lighting unit includes a plurality of light emitting elements aligned in a first direction. The displacement detecting unit is used for detecting displacement data of the electronic display apparatus in a second direction, where the second direction crosses to the first direction and an array area is defined between the first direction and the second direction. The storage unit is used to store a plurality of array image data. The data processing unit is used for receiving the displacement data forwarded from the displacement detecting unit and obtaining one of the array image data from the storage unit, which power of the light emitted by the light emitting elements is controlled according to the displacement data so as to display the array image data on the array area.

Abstract translation: 电子显示装置包括照明单元，位移检测单元，存储单元和数据处理单元。 照明单元包括沿第一方向排列的多个发光元件。 位移检测单元用于在第二方向与第一方向交叉的第二方向上检测电子显示装置的位移数据，并且在第一方向和第二方向之间限定阵列区域。 存储单元用于存储多个阵列图像数据。 数据处理单元用于接收从位移检测单元转发的位移数据，并从存储单元获取阵列图像数据中的一个，根据位移数据控制由发光元件发射的光的功率，从而 在阵列区域显示阵列图像数据。

公开(公告)号：US20070002210A1

公开(公告)日：2007-01-04

申请号：US11476862

申请日：2006-06-29

Applicant: David Ho ,  Zheng Zhang

Inventor： David Ho ,  Zheng Zhang

IPC: G02F1/1335

CPC classification number: G09G3/3413 ,  G02F2001/133626 ,  G09G2320/0242 ,  G09G2320/0626 ,  G09G2320/066 ,  G09G2320/0666 ,  G09G2360/144

Abstract: A system for automatically adjusting illumination of a screen according to the ambient brightness includes a detecting module and a central processing module. After the detecting module detects the ambient brightness, a set of data are generated by the central processing module of the system, then the central processing module will compare the set data with a predetermined data stored in a storage device module of the system. In the storage device module, the predetermined data represent a plurality of different brightness levels, and the set of data is also compared with the previously sampled data, and the result is used to determine whether or not to adjust the current backlight display illumination of a screen display module of the system. Adjusting the backlight display illumination of a keypad display module of the system can save the power of a battery installed in the system.

Abstract translation: 根据环境亮度自动调节屏幕的照明的系统包括检测模块和中央处理模块。 在检测模块检测到环境亮度之后，由系统的中央处理模块生成一组数据，然后中央处理模块将设置数据与存储在系统的存储设备模块中的预定数据进行比较。 在存储装置模块中，预定数据表示多个不同的亮度级别，并将该组数据与先前采样的数据进行比较，结果用于确定是否调整当前的背光显示照明 屏幕显示模块的系统。 调整系统的键盘显示模块的背光显示照明可以节省系统中安装的电池的电量。