公开(公告)号：US20180091610A1

公开(公告)日：2018-03-29

申请号：US15705869

申请日：2017-09-15

申请人： Bing Liu

发明人： Bing Liu

IPC分类号： H04L29/08 ,  H04L29/06 ,  H04L12/58

CPC分类号： H04L67/22 ,  H04L51/22 ,  H04L51/32 ,  H04L63/14 ,  H04L67/02

摘要： An engine, system and method for a domain social network that interconnects Internet users with at least domains owned by or of interest to those Internet users, and that may obtain and/or forward obtained dynamic data regarding those domains automatically, such as by web service or email service. The dynamic data may be used to filter and protect content and data of the respective domains, to protect users by identifying low quality web pages or malicious software or pages, to isolate or improve search results regarding the domain, and/or to improve Internet-based transaction flow, such as the creation of advertising.

公开(公告)号：US20160158155A1

公开(公告)日：2016-06-09

申请号：US14227277

申请日：2014-03-27

申请人： Makoto Murakami ,  Bing Liu

发明人： Makoto Murakami ,  Bing Liu

IPC分类号： A61K9/16 ,  G01N33/58 ,  A61K49/18

CPC分类号： A61K9/1617 ,  A61K49/1839 ,  B22F1/0014 ,  B22F1/0018 ,  B22F2304/054 ,  B82Y25/00 ,  C22C2202/02 ,  G01N33/58 ,  G01N2446/80 ,  G01R33/1269 ,  G01R33/1276 ,  Y10S977/773 ,  Y10S977/932

摘要： Disclosed is process for preparing magnetic nanoparticles (MNPs) that results in very sensitive MNPs that can be used in a variety of diagnostic and analytical methods. The MNPs exhibit superparamagnetism and find special use in giant magnetoresistance sensors (GMRS). The MNPs are created by a process that permits one to tune the size of nanoparticles to a range of from 10 to 20 nanometers with a very small particle size distribution of +/−2 nanometers or less. The MNPs can be tagged with a variety of markers and thus find use in many analytical assays, cell sorting techniques, imaging methods, drug delivery methods and cancer treatments. The inventive MNPs can be detected in magnetic file strengths of 2000 Oe or less.

摘要翻译： 公开了制备磁性纳米颗粒（MNPs）的方法，其导致非常敏感的MNP，其可用于各种诊断和分析方法。 MNPs表现出超顺磁性，并在巨磁电阻传感​​器（GMRS）中发现特殊用途。 通过允许将纳米颗粒的尺寸调整到10至20纳米范围的方法来产生MNP，其具有+/- 2纳米或更小的非常小的粒度分布。 MNP可以用多种标记进行标记，因此可用于许多分析测定，细胞分选技术，成像方法，药物递送方法和癌症治疗。 可以在2000Oe以下的磁文件强度中检测本发明的MNP。

公开(公告)号：US08858676B2

公开(公告)日：2014-10-14

申请号：US12951423

申请日：2010-11-22

申请人： Bing Liu ,  Zhendong Hu ,  Yong Che ,  Makoto Murakami

发明人： Bing Liu ,  Zhendong Hu ,  Yong Che ,  Makoto Murakami

IPC分类号： B22F9/14 ,  B01J19/12 ,  B22F9/04 ,  B22F1/00

CPC分类号： B01J19/121 ,  B22F1/0018 ,  B22F9/04 ,  B22F2999/00 ,  Y10S977/889 ,  B22F2202/11

摘要： A method for generating nanoparticles in a liquid comprises generating groups of ultrafast laser pulses, each pulse in a group having a pulse duration of from 10 femtoseconds to 200 picoseconds, and each group containing a plurality of pulses with a pulse separation of 1 to 100 nanoseconds and directing the groups of pulses at a target material in a liquid to ablate it. The multiple pulse group ablation produces nanoparticles with a reduced average size, a narrow size distribution, and improved production efficiency compared to prior pulsed ablation systems.

摘要翻译： 用于在液体中产生纳米颗粒的方法包括产生超快激光脉冲组，组中的每个脉冲具有10飞秒至200皮秒的脉冲持续时间，并且每组包含脉冲间隔为1至100纳秒的多个脉冲 并将脉冲组定向在液体中的目标材料以烧蚀它。 与先前的脉冲消融系统相比，多脉冲组消融产生具有降低的平均尺寸，窄尺寸分布和提高的生产效率的纳米颗粒。

公开(公告)号：US08713305B2

公开(公告)日：2014-04-29

申请号：US13560511

申请日：2012-07-27

申请人： Bing Liu ,  Yejian Xu ,  Meng Xu ,  Chengjiao Nie

发明人： Bing Liu ,  Yejian Xu ,  Meng Xu ,  Chengjiao Nie

IPC分类号： H04L29/06

CPC分类号： H04L63/0272 ,  H04L63/029 ,  H04L63/166

摘要： Embodiment of the present invention provides a packet transmission method. The method includes: receiving an encrypted packet sent by a client by using a virtual private network (VPN) tunnel, wherein the encrypted packet is sent by the client after the client determines, according to a preset control policy, that the control policy comprises an Internet Protocol (IP) address and a port number that are the same as a destination IP address and a destination port number of a packet to be sent and encrypts the packet to be sent, and the control policy comprises information about an IP address and a port number of an intranet server that can exchange a packet with a security socket layer protocol (SSL) VPN server; decrypting the encrypted packet; and sending the decrypted packet to a corresponding intranet server, wherein a source IP address of the decrypted packet is an external network IP address.

摘要翻译： 本发明的实施例提供一种分组传输方法。 该方法包括：通过使用虚拟专用网（VPN）隧道来接收由客户端发送的加密分组，其中在客户端根据预设控制策略确定控制策略包括 互联网协议（IP）地址和与要发送的分组的目的地IP地址和目的地端口号相同的端口号，并对要发送的分组进行加密，并且控制策略包括关于IP地址和 可以与安全套接字层协议（SSL）VPN服务器交换数据包的内部网服务器的端口号; 解密加密分组; 并将解密的分组发送到对应的内联网服务器，其中解密的分组的源IP地址是外部网络IP地址。

公开(公告)号：US20140109079A1

公开(公告)日：2014-04-17

申请号：US14015277

申请日：2013-08-30

申请人： William Cheng ,  Kenneth Hwang ,  Ravi Kannan ,  Babu Katchapalayam ,  Bing Liu ,  Balaji Narasimhan ,  Gopal Ramanujam ,  Jonathan Tran

发明人： William Cheng ,  Kenneth Hwang ,  Ravi Kannan ,  Babu Katchapalayam ,  Bing Liu ,  Balaji Narasimhan ,  Gopal Ramanujam ,  Jonathan Tran

IPC分类号： G06F9/445

CPC分类号： G06F8/62 ,  G06F8/61 ,  G06F8/65 ,  G06Q30/06 ,  H04L29/06 ,  H04L67/34 ,  H04L69/329

摘要： A computer program product is embodied on a non-transitory computer readable medium. The computer program product comprises computer code to display a plurality of first indicia presented in a list, where each first indicia indicates a software product, and computer code to display a second indicia associated with a highlighted one of the first indicia. The second indicia comprises information about the software product indicated by the highlighted first indicia. The computer program product additionally comprises computer code to display a third indicia associated with the highlighted first indicia and indicate the availability of a software update for the software product indicated by the highlighted first indicia, and computer code to display a fourth indicia associated with the highlighted first indicia. The fourth indicia facilitates the retrieval of the software update.

公开(公告)号：US08456135B2

公开(公告)日：2013-06-04

申请号：US13002978

申请日：2009-07-07

申请人： Bing Liu

发明人： Bing Liu

IPC分类号： H02J7/00 ,  H02H3/247 ,  B60K1/00

CPC分类号： B60L3/0046 ,  B60L11/1803 ,  B60L11/1857 ,  B60L2250/10 ,  G01R31/362 ,  H01M10/48 ,  H01M2010/4271 ,  H01M2220/20 ,  Y02T10/7005 ,  Y02T10/705

摘要： A high voltage output monitoring device and system of a power battery comprises a monitoring module, a control module and a central processor module, wherein the monitoring module carries out high voltage output monitoring, pre-charge monitoring and relay switching times monitoring; the control module controls a relay switch; the central processor module carries out processing and analysis of monitor signals, packs relay state signals, sends the packed relay state signals to a battery management system (8), prognosticates a relay health condition, sends alarming signals to the battery management system (8), judges the pre-charge state, controls a high voltage system to be opened or closed, receives the control of the battery management system, and forces the high voltage system to be opened or closed. By using the monitoring device of the present invention, it is feasible to prognosticate the lift of high voltage relay, send the relay health alarm signal in real time and to avoid the relay from causing hazard when it is damaged and cannot be closed; Furthermore, it is favorable for extending the life of battery by monitoring and controlling the pre-charge state of power battery.

摘要翻译： 电力电池的高压输出监视装置和系统包括监控模块，控制模块和中央处理器模块，其中监控模块执行高压输出监控，预充电监控和继电器切换时间监控; 控制模块控制继电器开关; 中央处理器模块对监控信号进行处理和分析，对继电器状态信号进行封装，将封装的继电器状态信号发送到电池管理系统（8），预测继电器健康状况，向电池管理系统（8）发送报警信号， ，判断预充电状态，控制要打开或关闭的高压系统，接收电池管理系统的控制，并迫使高压系统打开或关闭。 通过使用本发明的监视装置，可以预测高压继电器的升力，实时发送继电器健康报警信号，避免继电器损坏而不能关闭时发生危险; 此外，通过监视和控制动力电池的预充电状态来延长电池寿命是有利的。

公开(公告)号：US20130117370A1

公开(公告)日：2013-05-09

申请号：US13661943

申请日：2012-10-26

申请人： Bing Liu

发明人： Bing Liu

IPC分类号： H04L29/08

CPC分类号： H04L67/22 ,  H04L51/22 ,  H04L51/32 ,  H04L63/14 ,  H04L67/02

摘要： An engine, system and method for a domain social network that interconnects Internet users with at least domains owned by or of interest to those Internet users, and that may obtain and/or forward obtained dynamic data regarding those domains automatically, such as by web service or email service. The dynamic data may be used to filter and protect content and data of the respective domains, to protect users by identifying low quality web pages or malicious software or pages, to isolate or improve search results regarding the domain, and/or to improve Internet-based transaction flow, such as the creation of advertising.

摘要翻译： 用于域网络的引擎，系统和方法，其将互联网用户与至少由这些因特网用户所拥有或感兴趣的域互连，并且可以自动地获得和/或转发关于这些域的获得的动态数据，例如通过web服务 或电子邮件服务。 动态数据可以用于过滤和保护各个域的内容和数据，以通过识别低质量网页或恶意软件或页面来保护用户，以隔离或改进关于域的搜索结果，和/或改善互联网 - 基于交易流程，如创建广告。

公开(公告)号：US20120269817A1

公开(公告)日：2012-10-25

申请号：US13057728

申请日：2009-08-04

申请人： Zhuozhi Wang ,  John E. Murphy ,  Junliang Pan ,  Haiyan Jiang ,  Bing Liu

发明人： Zhuozhi Wang ,  John E. Murphy ,  Junliang Pan ,  Haiyan Jiang ,  Bing Liu

IPC分类号： A61K39/395 ,  C12P21/08 ,  C12N15/13 ,  C07K16/18 ,  A61P7/04

摘要： Isolated monoclonal antibodies that bind human tissue factor pathway inhibitor (TFPI) and the isolated nucleic acid molecules encoding them are provided. Pharmaceutical compositions comprising the anti-TFPI monoclonal antibodies and methods of treating deficiencies or defects in coagulation by administration of the antibodies are also provided. Methods of producing the antibodies are also provided.

摘要翻译： 提供了结合人组织因子途径抑制剂（TFPI）的分离的单克隆抗体和编码它们的分离的核酸分子。 还提供了包含抗TFPI单克隆抗体的药物组合物和通过施用抗体治疗缺血或凝血缺陷的方法。 还提供了产生抗体的方法。

公开(公告)号：US08163559B2

公开(公告)日：2012-04-24

申请号：US13016571

申请日：2011-01-28

申请人： Yanmei Qiao ,  Bing Liu ,  Xiangping Meng ,  Wenjuan Xu ,  Mulong Liu

发明人： Yanmei Qiao ,  Bing Liu ,  Xiangping Meng ,  Wenjuan Xu ,  Mulong Liu

IPC分类号： G01N33/48 ,  C12N5/078

CPC分类号： G01N33/5094 ,  Y10T436/10 ,  Y10T436/101666 ,  Y10T436/107497 ,  Y10T436/108331 ,  Y10T436/25

摘要： A reagent for four-part differentiation of white blood cells is provided. In one embodiment the reagent has an osmolality below 50 mOsm/kg H2O. A method for differentiating white blood cells using the reagent is also provided. The disclosure provides for a rapid lysis of red blood cells and four-part differentiation of white blood cells. The reagent may be simple in components and a surfactant is not necessary, but optional. A wide range of pH values may be suitable for the reagent.

摘要翻译： 提供了白细胞四部分分化试剂。 在一个实施方案中，试剂的重量摩尔渗透压浓度低于50mOsm / kg H 2 O。 还提供了使用该试剂来分化白细胞的方法。 本公开提供红细胞的快速溶解和白细胞的四部分分化。 试剂可以是简单的组分，并且表面活性剂不是必需的，但是是任选的。 大范围的pH值可能适用于试剂。

公开(公告)号：US20110291019A1

公开(公告)日：2011-12-01

申请号：US13115681

申请日：2011-05-25

申请人： Jie Yuan ,  Bing Liu

发明人： Jie Yuan ,  Bing Liu

IPC分类号： G01T1/24

CPC分类号： G01T1/249 ,  G01T1/247

摘要： The invention provides a CMOS CT detector design with high linearity, quantum-limited noise, good scalability, high fill factor with a single CMOS chip utilizing synchronous partial quantization. The CMOS CT detector includes a pixel array, digital column buses, analog column buses, column processing circuits, a shift register, a control signal generation circuit, and a reference generation circuit, and implements a synchronous partial quantization scheme with reset, integration and analog readout phases. Each pixel of the pixel array further includes a photodiode; an integration capacitor; an OPAMP; a reset switch; a comparator; a 1-bit dynamic random-access-memory (DRAM) cell; a circuit block for enabling subtraction of a substantially fixed amount of charge from the integrated photocharge if the integrated photovoltage increases beyond the reference voltage; an integration node; an analog buffer; and a switch coupled between the output of the DRAM cell and the digital column bus. The inclusion of a level-shifter and a current front-end improves the linearity of the detector.

摘要翻译： 本发明提供了具有高线性，量子限制噪声，良好的可扩展性，高填充率的CMOS CT检测器设计，其具有利用同步部分量化的单个CMOS芯片。 CMOS CT检测器包括像素阵列，数字列总线，模拟列总线，列处理电路，移位寄存器，控制信号生成电路和参考生成电路，并实现具有复位，积分和模拟的同步部分量化方案 读出阶段。 像素阵列的每个像素还包括光电二极管; 集成电容器; 一个OPAMP; 复位开关; 比较器 1位动态随机存取存储器（DRAM）单元; 电路块，用于如果集成的光电压增加超过参考电压，则能够从集成的光电荷中减去基本固定的电荷量; 集成节点; 模拟缓冲器 以及耦合在DRAM单元的输出和数字列总线之间的开关。 包括电平转换器和电流前端提高了检测器的线性度。