公开(公告)号：US09119615B2

公开(公告)日：2015-09-01

申请号：US13326625

申请日：2011-12-15

申请人： Kevin D. Felder ,  Lawrence Crainich ,  Justin W. Sherrill ,  Jason L. Harris ,  Mark S. Zeiner ,  Brian F. DiNardo

发明人： Kevin D. Felder ,  Lawrence Crainich ,  Justin W. Sherrill ,  Jason L. Harris ,  Mark S. Zeiner ,  Brian F. DiNardo

IPC分类号： A61B17/068 ,  A61B17/072

CPC分类号： A61B17/068 ,  A61B17/00234 ,  A61B17/0686 ,  A61B17/072 ,  A61B17/07207 ,  A61B90/361 ,  A61B2017/00278 ,  A61B2017/00314 ,  A61B2017/00327 ,  A61B2017/00349 ,  A61B2017/00353 ,  A61B2017/00818 ,  A61B2017/00862 ,  A61B2017/0647 ,  A61B2017/07271 ,  A61B2017/07278 ,  A61B2017/2926 ,  A61B2017/2936 ,  A61B2017/2941 ,  A61B2017/2943 ,  A61B2017/2944 ,  A61B2017/308 ,  A61F5/0083

摘要： Devices and methods are provided for forming and securing a tissue plication. More particularly, the devices and methods of the present invention can be used to create multiple tissue folds on an anterior and posterior wall of a stomach cavity to reduce the volume thereof. In one aspect, a tissue acquisition and fixation system is described that includes a staple applying assembly having first and second jaws, and a tissue acquisition member that extends substantially parallel to a plane running through the first and second jaws. The tissue acquisition member is effective to engage and position tissue between the first and second jaws, and the jaws are effective to apply at least one staple to the tissue engaged therebetween.

摘要翻译： 提供了用于形成和固定组织浸液的装置和方法。 更具体地，本发明的装置和方法可用于在胃腔的前壁和后壁上产生多个组织折叠以减小其体积。 在一个方面，描述了一种组织采集和固定系统，其包括具有第一和第二钳口的缝合钉施加组件，以及基本上平行于穿过第一和第二钳口的平面延伸的组织采集构件。 组织采集构件有效地在第一和第二钳口之间接合和定位组织，并且钳口有效地将至少一个钉施加到接合在其间的组织。

公开(公告)号：US09113867B2

公开(公告)日：2015-08-25

申请号：US13326643

申请日：2011-12-15

申请人： Kevin D. Felder ,  Lawrence Crainich ,  Justin W. Sherrill ,  Jason L. Harris ,  Mark S. Zeiner ,  Brian F. DiNardo

发明人： Kevin D. Felder ,  Lawrence Crainich ,  Justin W. Sherrill ,  Jason L. Harris ,  Mark S. Zeiner ,  Brian F. DiNardo

IPC分类号： A61B17/068 ,  A61B17/072 ,  A61B17/00 ,  A61B19/00 ,  A61B17/064 ,  A61B17/29 ,  A61B17/30 ,  A61F5/00

CPC分类号： A61B17/068 ,  A61B17/00234 ,  A61B17/0686 ,  A61B17/072 ,  A61B17/07207 ,  A61B90/361 ,  A61B2017/00278 ,  A61B2017/00314 ,  A61B2017/00327 ,  A61B2017/00349 ,  A61B2017/00353 ,  A61B2017/00818 ,  A61B2017/00862 ,  A61B2017/0647 ,  A61B2017/07271 ,  A61B2017/07278 ,  A61B2017/2926 ,  A61B2017/2936 ,  A61B2017/2941 ,  A61B2017/2943 ,  A61B2017/2944 ,  A61B2017/308 ,  A61F5/0083

摘要： Devices and methods are provided for forming and securing a tissue plication. More particularly, the devices and methods of the present invention can be used to create tissue folds on an anterior and posterior wall of a stomach cavity to reduce the volume thereof. In one aspect, a tissue acquisition and fixation system is disclosed that includes an elongate shaft, an end effector coupled to the elongate shaft and having first and second jaws, and a tissue acquisition member coupled to the end effector by a linkage assembly. At least a portion of the linkage assembly and tissue acquisition member are slidably movable in a direction parallel to a longitudinal axis of the jaws. Further, the tissue acquisition member is vertically movable relative to the end effector such that a distance between a longitudinal axis of the tissue acquisition member and the jaws can be adjusted.

摘要翻译： 提供了用于形成和固定组织浸液的装置和方法。 更具体地，本发明的装置和方法可用于在胃腔的前壁和后壁上产生组织褶皱，以减小其体积。 在一个方面，公开了一种组织采集和固定系统，其包括细长轴，连接到细长轴并具有第一和第二钳口的端部执行器，以及通过连杆组件联接到末端执行器的组织采集构件。 连杆组件和组织采集构件的至少一部分可在平行于钳口的纵向轴线的方向上可滑动地移动。 此外，组织采集构件相对于末端执行器可垂直移动，使得可以调节组织采集构件的纵向轴线与夹爪之间的距离。

公开(公告)号：US08812100B2

公开(公告)日：2014-08-19

申请号：US13468858

申请日：2012-05-10

申请人： James W. Voegele ,  Thomas E. Albrecht ,  Tamara C. Baynham ,  David Cagle ,  Anthony R. DiUbaldi ,  Jason L. Harris ,  Michael A. Murray ,  Mark S. Zeiner ,  Jacob Crabtree

发明人： James W. Voegele ,  Thomas E. Albrecht ,  Tamara C. Baynham ,  David Cagle ,  Anthony R. DiUbaldi ,  Jason L. Harris ,  Michael A. Murray ,  Mark S. Zeiner ,  Jacob Crabtree

IPC分类号： A61N1/00

CPC分类号： A61N1/36017 ,  A61N1/0408 ,  A61N1/0456 ,  A61N1/0476 ,  A61N1/0492 ,  A61N1/205 ,  A61N1/36014 ,  A61N1/36085

摘要： Self-positioning of at least a portion of a transdermal electrical stimulation patch within a target area (e.g., supraclavicular fossa region) of a human body to activate a depot of brown adipose tissue therein. An electric field is generated using the electrical stimulation patch to activate the brown adipose tissue within the supraclavicular fossa region of the body. The patch is self-positioned using one or more anatomical points (e.g., anatomical landmarks and/or anatomical features) or markings on the body. Brown adipose tissue may also be activated by applying an electrical signal to a body piercing partially implanted proximate a target area in which the tissue is disposed.

摘要翻译： 至少一部分透皮电刺激贴片在人体的目标区域（例如，锁骨上窝窝区域）内自我定位，以激活其中的棕色脂肪组织储存库。 使用电刺激贴片产生电场以激活身体锁骨内窝内的棕色脂肪组织。 贴片使用人体上的一个或多个解剖点（例如解剖学标记和/或解剖特征）或标记进行自定位。 褐色脂肪组织也可以通过将电信号施加到靠近其中设置组织的目标区域部分植入的身体来激活。

公开(公告)号：US20140180192A1

公开(公告)日：2014-06-26

申请号：US14239899

申请日：2012-08-23

申请人： Mark S. Ortiz ,  Mark S. Zeiner ,  Jason L. Harris ,  Matthew D. Holcomb ,  Michael J. Stokes

发明人： Mark S. Ortiz ,  Mark S. Zeiner ,  Jason L. Harris ,  Matthew D. Holcomb ,  Michael J. Stokes

IPC分类号： A61F5/00

CPC分类号： A61F5/0076 ,  A61F5/0089

摘要： Endoluminal sleeve device (1) for internally lining a section of the GI tract, comprising a sleeve (2) configured for deployment inside a GI tract, the sleeve (2) having walls of a flexible material defining a sleeve lumen (3), a proximal end (4) defining a proximal lumen opening (5), and a distal end (6) defining a distal lumen opening (7), a tubular anchoring portion (8) forming said proximal lumen end (4) and defining anchoring seats (9) delimited each one by an annular collar (11) forming an opening through which adjacent tissue portions (12) can be pulled into the anchoring seats (9), expansion means adapted to act on the tissue portions (12) arranged in the anchoring seats (9) such that the tissue portions (12) expand to a dimension greater than the opening of the annular collar (11).

摘要翻译： 用于内部衬里胃肠道部分的内腔套管装置（1），包括构造成用于部署在胃肠道内的套筒（2），所述套管（2）具有限定套管内腔（3）的柔性材料的壁， 限定近端腔开口（5）的近端（4）和限定远端内腔开口（7）的远端（6），形成所述近端内腔端部（4）的管状锚固部分（8） 9）通过形成开口的环形套环（11）限定，相邻组织部分（12）可以通过该开口被拉入锚固座（9），适于作用在布置在锚固中的组织部分（12）上的膨胀装置 座（9），使得组织部分（12）膨胀成大于环形套环（11）的开口的尺寸。

公开(公告)号：US20130304175A1

公开(公告)日：2013-11-14

申请号：US13468858

申请日：2012-05-10

申请人： James W. Voegele ,  Thomas E. Albrecht ,  Tamara C. Baynham ,  David Cagle ,  Jacob Crabtree ,  Anthony R. DiUbaldi ,  Jason L. Harris ,  Michael A. Murray ,  Mark S. Zeiner

发明人： James W. Voegele ,  Thomas E. Albrecht ,  Tamara C. Baynham ,  David Cagle ,  Jacob Crabtree ,  Anthony R. DiUbaldi ,  Jason L. Harris ,  Michael A. Murray ,  Mark S. Zeiner

IPC分类号： A61N1/04

CPC分类号： A61N1/36017 ,  A61N1/0408 ,  A61N1/0456 ,  A61N1/0476 ,  A61N1/0492 ,  A61N1/205 ,  A61N1/36014 ,  A61N1/36085

摘要： Self-positioning of at least a portion of a transdermal electrical stimulation patch within a target area (e.g., supraclavicular fossa region) of a human body to activate a depot of brown adipose tissue therein. An electric field is generated using the electrical stimulation patch to activate the brown adipose tissue within the supraclavicular fossa region of the body. The patch is self-positioned using one or more anatomical points (e.g., anatomical landmarks and/or anatomical features) or markings on the body. Brown adipose tissue may also be activated by applying an electrical signal to a body piercing partially implanted proximate a target area in which the tissue is disposed.

摘要翻译： 至少一部分透皮电刺激贴片在人体的目标区域（例如，锁骨上窝窝区域）内自我定位，以激活其中的棕色脂肪组织储存库。 使用电刺激贴片产生电场以激活身体锁骨内窝内的棕色脂肪组织。 贴片使用人体上的一个或多个解剖点（例如解剖学标记和/或解剖特征）或标记进行自定位。 褐色脂肪组织也可以通过将电信号施加到靠近其中设置组织的目标区域部分植入的身体来激活。

公开(公告)号：US08551118B2

公开(公告)日：2013-10-08

申请号：US11779322

申请日：2007-07-18

申请人： Mark S. Zeiner ,  Jason L. Harris ,  Michael J. Stokes ,  Lawrence Crainich ,  Thomas E. Albrecht ,  Daniel Alesi

发明人： Mark S. Zeiner ,  Jason L. Harris ,  Michael J. Stokes ,  Lawrence Crainich ,  Thomas E. Albrecht ,  Daniel Alesi

IPC分类号： A61B17/10

CPC分类号： A61B17/0401 ,  A61B17/3421 ,  A61B17/3478 ,  A61B2017/00278 ,  A61B2017/00818 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0458 ,  A61B2017/0477 ,  A61B2017/349 ,  A61F5/0086

摘要： A method for treating obesity by reducing the volume and/or alter the functioning of the gastric cavity to limit food consumption and induce early satiety. The method includes accessing the cavity endoscopically to visualize the interior of the cavity. The peritoneal cavity is accessed through a small incision in the abdominal wall. Using endoscopic visualization, suture anchoring devices are introduced into the peritoneal cavity through the incision and deployed from the exterior surface through the gastric cavity wall. Suture from pairs of the anchoring devices is drawn through the gastric cavity wall and tightened outside of the cavity to form a serosa to serosa plication. Any number of plications may be formed in the cavity wall and the contacting tissue within a plication may be treated to promote healing and a more durable bond.

摘要翻译： 一种通过减少体积和/或改变胃腔功能以限制食物消耗并诱发早期饱腹感来治疗肥胖症的方法。 该方法包括内窥镜进入空腔以使空腔的内部可视化。 腹腔通过腹壁的小切口进入。 使用内窥镜可视化，通过切口将缝线锚定装置引入腹腔，并从外表面通过胃腔壁展开。 从成对的锚定装置缝合穿过胃腔壁，并在空腔外部紧固以形成浆膜至浆膜淤积。 可以在空腔壁中形成任何数量的塌陷，并且可以处理塌陷期间的接触组织以促进愈合和更持久的粘合。

公开(公告)号：US20130253536A1

公开(公告)日：2013-09-26

申请号：US13425900

申请日：2012-03-21

申请人： Jason L. Harris ,  Kevin D. Felder ,  Justin W. Sherrill

发明人： Jason L. Harris ,  Kevin D. Felder ,  Justin W. Sherrill

IPC分类号： A61B17/03

CPC分类号： A61B17/0401 ,  A61B17/0487 ,  A61B17/29 ,  A61B2017/00349 ,  A61B2017/00818 ,  A61B2017/0404 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/2905 ,  A61B2017/2927

摘要： Devices and methods for forming and securing a tissue plication are disclosed herein. In one aspect, a tissue manipulation device is described that includes a first jaw member pivotally coupled to a distal end of an elongate shaft and having an articulating portion located distal to the proximal end of the first jaw member. The device also includes a second jaw member pivotally coupled to the first jaw member such that the jaws move in a first plane, and a fastener delivery member attached to the second jaw member. The articulating portion of the first jaw member is configured to move the first and second jaw members between a straight configuration in which a longitudinal axis of the elongate shaft is contained within the first plane and an articulated configuration in which the longitudinal axis of the elongate shaft is transverse to the first plane.

公开(公告)号：US20130193184A1

公开(公告)日：2013-08-01

申请号：US13371684

申请日：2012-02-13

申请人： Matthew D. Holcomb ,  Jason L. Harris ,  Michael J. Stokes ,  Mark S. Zeiner ,  Jonathan B. O'Keefe ,  Keith D. Boudreau ,  Jeffrey C. Cerier

发明人： Matthew D. Holcomb ,  Jason L. Harris ,  Michael J. Stokes ,  Mark S. Zeiner ,  Jonathan B. O'Keefe ,  Keith D. Boudreau ,  Jeffrey C. Cerier

IPC分类号： A61B17/068

CPC分类号： A61B17/0644 ,  A61B17/0684 ,  A61B2017/00818

摘要： A surgical fastener applier having a handle and a fastener housing extending from the handle. The housing contains at least one anvil movable within the staple housing, the anvil has a proximal position and a distal position. When in the distal position a distal end of the anvil extends distal to the distal end of the staple housing. The housing contains a plurality of surgical fasteners each of which in the shape of a loop. At least one of the fasteners is placed around a portion of the anvil when in the distal position. The applier has a first mechanism for moving the anvil distally after a fastener has been deployed, and a second mechanism for moving the anvil distally after a fastener has been deployed. The second means is independent of the first means.

摘要翻译： 具有手柄和从手柄延伸的紧固件外壳的手术紧固件施加器。 壳体包含至少一个在钉仓壳体内可移动的砧座，砧座具有近端位置和远端位置。 当处于远端位置时，砧座的远端延伸到钉仓远端的远端。 壳体包含多个环形形状的外科紧固件。 当处于远端位置时，至少一个紧固件被放置在砧座的一部分周围。 施放器具有用于在紧固件展开之后向远侧移动砧座的第一机构，以及用于在紧固件展开后向远侧移动砧座的第二机构。 第二种手段是独立于第一种手段。

公开(公告)号：US20130193183A1

公开(公告)日：2013-08-01

申请号：US13371678

申请日：2012-02-13

申请人： Matthew D. Holcomb ,  Jason L. Harris ,  Michael J. Stokes ,  Mark S. Zeiner ,  Jonathan B. O'Keefe ,  Keith D. Boudreau ,  Jeffrey C. Cerier

发明人： Matthew D. Holcomb ,  Jason L. Harris ,  Michael J. Stokes ,  Mark S. Zeiner ,  Jonathan B. O'Keefe ,  Keith D. Boudreau ,  Jeffrey C. Cerier

IPC分类号： A61B17/068

CPC分类号： A61B17/0644 ,  A61B17/0684 ,  A61B2017/00818

摘要： A fastener applying device including a staple housing having a proximal end attached to a handle, a distal end, and a longitudinal axis therebetween. There is at least one fastener within the housing. The device also includes an anvil movable within the staple housing. The anvil has a proximal position and a distal position, wherein when in the distal position a distal end of the anvil extends distal to the distal end of the staple housing by a distance. The device also includes an adjustment nut connecting the staple housing to the handle. Rotation of the adjustment nut changes the distance.

摘要翻译： 一种紧固件施加装置，包括具有附接到手柄的近端的钉仓，其远端和它们之间的纵向轴线。 壳体内至少有一个紧固件。 该装置还包括可在钉仓内移动的砧座。 砧座具有近端位置和远端位置，其中当远端位置时，砧座的远端远离钉钉仓的远端延伸一定距离。 该装置还包括将钉仓连接到把手的调节螺母。 调整螺母的旋转会改变距离。

公开(公告)号：US08469252B2

公开(公告)日：2013-06-25

申请号：US13015966

申请日：2011-01-28

申请人： Matthew D. Holcomb ,  Jason L. Harris ,  Michael J. Stokes ,  Mark S. Zeiner ,  Jonathan B. O'Keefe ,  Keith D. Boudreau ,  Jeffrey C. Cerier

发明人： Matthew D. Holcomb ,  Jason L. Harris ,  Michael J. Stokes ,  Mark S. Zeiner ,  Jonathan B. O'Keefe ,  Keith D. Boudreau ,  Jeffrey C. Cerier

IPC分类号： A61B17/068

CPC分类号： A61B17/0684 ,  A61B17/0644 ,  A61B17/0682 ,  A61B2017/0053 ,  A61B2017/00818 ,  A61B2017/0488 ,  A61B2017/0645 ,  A61B2017/0725

摘要： A fastener applying device including a staple housing having a proximal end attached to a handle, a distal end, and a longitudinal axis therebetween. There is at least one fastener within the housing. The device also includes an anvil movable within the staple housing. The anvil has a proximal position and a distal position, wherein when in the distal position a distal end of the anvil extends distal to the distal end of the staple housing by a distance. The device also includes an adjustment nut connecting the staple housing to the handle. Rotation of the adjustment nut changes the distance.

摘要翻译： 一种紧固件施加装置，包括具有附接到手柄的近端的钉仓，其远端和它们之间的纵向轴线。 壳体内至少有一个紧固件。 该装置还包括可在钉仓内移动的砧座。 砧座具有近端位置和远端位置，其中当远端位置时，砧座的远端远离钉钉仓的远端延伸一定距离。 该装置还包括将钉仓连接到把手的调节螺母。 调整螺母的旋转会改变距离。