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    System and process and for replicating soft tissue anatomy using a for implant supported fixed prostheses using 3D printed multi-purpose prototype
    82.
    发明授权
    System and process and for replicating soft tissue anatomy using a for implant supported fixed prostheses using 3D printed multi-purpose prototype 有权

    公开(公告)号：US11638630B1

    公开(公告)日：2023-05-02

    申请号：US17938137

    申请日：2022-10-05

    Applicant: Kuwait University

    Inventor： Fawaz AlZoebi

    IPC: A61C8/00 ,  G16H20/40

    Abstract: A process for replicating soft tissue anatomy of a dental patient prior to preparing an implant-supported fixed prosthesis is disclosed. The process may include: securing an interim prosthesis intra-orally in the dental patient for a predetermined time, after implants of the dental patient are osseointegrated, to evaluate the interim prosthesis based on a plurality of parameters within the mouth of the dental patient; printing a three-dimensional printed-resin prototype having an intaglio surface based on the evaluated interim prosthesis; attaching the three-dimensional printed-resin prototype into the implants; and injecting a low viscosity elastomeric impression material between the intaglio surface of the three-dimensional printed-resin prototype and the soft tissue of the dental patient to obtain a soft tissue replica for preparing the implant-supported fixed prosthesis.

    OXAZOLIDINONE HYDROXAMIC ACID DERIVATIVES
    83.
    发明申请
    OXAZOLIDINONE HYDROXAMIC ACID DERIVATIVES 有权

    公开(公告)号：US20210238151A1

    公开(公告)日：2021-08-05

    申请号：US17145357

    申请日：2021-01-10

    Applicant: KUWAIT UNIVERSITY

    Inventor： CHARLES IFEAMALUME EZEAMUZIE ,  OLUDOTUN ADEBAYO PHILLIPS

    IPC: C07D263/06 ,  A61P37/08 ,  A61P11/06

    Abstract: Oxazolidione hydroxamic acid derivatives of the general formula (I): where R1 is hydrogen or hexanoyl and R2 is amino, methyl, ethyl, propyl, isopropyl, cyclopropyl, butyl, isobutyl, cyclobutyl, pentyl, cyclopentyl, hexyl or heptyl, and pharmaceutically acceptable salts thereof, act as dual inhibitors of 5-lipoxygenase and mast cell degranulation. The oxazolidinone hydroxamic acid derivatives or pharmaceutically acceptable salts thereof can be used in the prevention and treatment of asthma and allergies, as well as inflammatory conditions.

    Method of treating delayed healing of a wound associated with diabetes
    84.
    发明授权
    Method of treating delayed healing of a wound associated with diabetes 有权

    公开(公告)号：US10206896B2

    公开(公告)日：2019-02-19

    申请号：US16020517

    申请日：2018-06-27

    Applicant: KUWAIT UNIVERSITY

    Inventor： Milad S. Bitar ,  Fahd Al-Mulla

    IPC: C07H21/02 ,  C07H21/04 ,  A61K31/70 ,  A61K31/19 ,  C12N15/113 ,  A61K31/56 ,  C12N5/00

    Abstract: The method of treating delayed healing of a wound associated with diabetes includes administering to the wound a composition comprising an anti-senescence compound and a pharmaceutically acceptable carrier. The anti-senescence compound may be 18α-Glycyrrhetinic acid, a Caveolin-1 (Cav-1) inhibitory compound, or a Polymerase I Transcript Release Factor (PTRF-1) inhibitory compound. The anti-senescence compound may be effective in preventing and/or reversing premature cellular senescence. The anti-senescence compound may be effective in promoting healing of a wound, e.g., delayed or incompletely healed wound. The anti-senescence compound may be effective in promoting healing of a delayed healing wound or chronic wound of a diabetic patient, such as a diabetic ulcer or venous ulcer.

    Cooling system for patients with fever
    87.
    发明授权
    Cooling system for patients with fever 有权

    公开(公告)号：US10045880B2

    公开(公告)日：2018-08-14

    申请号：US15003739

    申请日：2016-01-21

    Applicant: KUWAIT UNIVERSITY

    Inventor： Bader Shafaqa Al-Anzi

    IPC: A61F7/02 ,  A61F7/00 ,  A61B5/01 ,  A61B5/00

    Abstract: The cooling system for patients with fever is a mechanical, fluid-based system for cooling patients suffering from fever. The cooling system for patients with fever includes a reservoir for containing a cooling fluid, which is maintained at a desired temperature. A temperature sensor is received in the reservoir. The temperature sensor is immersed in the cooling fluid for measuring the temperature thereof. A chiller is also received in the reservoir for selectively cooling the cooling fluid when the temperature thereof, measured by the temperature sensor, is above a pre-set temperature threshold. The reservoir communicates with a cooling pad, which is formed from a padded layer having at least one channel embedded therein. At least one pump and tubing is provided for circulating the cooling fluid through the reservoir and the cooling pad. In use, the cooling pad is applied to the skin of a patient with a fever.

    System and method for determining the feedback capacity of information distributed in a complex network
    88.
    发明授权
    System and method for determining the feedback capacity of information distributed in a complex network 有权

    公开(公告)号：US09904961B2

    公开(公告)日：2018-02-27

    申请号：US14706940

    申请日：2015-05-07

    Applicant: KUWAIT UNIVERSITY

    Inventor： Ghufran Abdullah Al-Shiridah ,  Khaled Mahdi ,  Maytham Safar

    IPC: G06F15/16 ,  G06Q50/00 ,  H04L12/24

    CPC classification number: G06Q50/01 ,  H04L41/145 ,  H04L41/16

    Abstract: The system and method for determining the feedback capacity of information distributed in a complex network determines feedback capacity as information is received and diffused throughout the network. Traditionally, real networks, such as computer networks, were used in determining network feedback. However, current complex networks typically incorporate graphing models for network analysis. The system and method provide a process to determine the quality of a complex network with respect to feedback capacity, such as can be determined by a corresponding Belief Propagation algorithm and a corresponding entropy equation. The system and method can also determine the cyclic entropy per penetration in a complex network, the depth penetration for nodes in the complex network and a plurality of cycle counts per node in the complex network based on a source node.

    METHOD OF TREATING DELAYED HEALING OF A WOUND ASSOCIATED WITH DIABETES
    89.
    发明申请
    METHOD OF TREATING DELAYED HEALING OF A WOUND ASSOCIATED WITH DIABETES 审中-公开
    治疗与糖尿病相关的延迟疗法的方法

    公开(公告)号：US20150352064A1

    公开(公告)日：2015-12-10

    申请号：US14301301

    申请日：2014-06-10

    Applicant: Kuwait University

    Inventor： MILAD S. BITAR ,  FAHD AL-MULLA

    IPC: A61K31/19 ,  C12N15/113

    CPC classification number: A61K31/19 ,  A61K31/56 ,  C12N15/113 ,  C12N2310/11 ,  C12N2310/14 ,  C12N2310/3233

    Abstract: The method of treating delayed healing of a wound associated with diabetes includes administering to the wound a composition comprising an anti-senescence compound and a pharmaceutically acceptable carrier. The anti-senescence compound may be 18α-Glycyrrhetinic acid, a Caveolin-1 (Cav-1) inhibitory compound, or a Polymerase I Transcript Release Factor (PTRF-1) inhibitory compound. The anti-senescence compound may be effective in preventing and/or reversing premature cellular senescence. The anti-senescence compound may be effective in promoting healing of a wound, e.g., delayed or incompletely healed wound. The anti-senescence compound may be effective in promoting healing of a delayed healing wound or chronic wound of a diabetic patient, such as a diabetic ulcer or venous ulcer.

    Abstract translation: 治疗与糖尿病相关的伤口的延迟愈合的方法包括向伤口施用包含抗衰老化合物和药学上可接受的载体的组合物。 抗衰老化合物可以是18α-甘草次酸，窖蛋白-1（Cav-1）抑制化合物或聚合酶I转录物释放因子（PTRF-1）抑制化合物。 抗衰老化合物可以有效预防和/或逆转过早的细胞衰老。 抗衰老化合物可有效促进伤口愈合，例如延迟或不完全愈合的伤口。 抗衰老化合物可有效促进糖尿病患者如糖尿病性溃疡或静脉溃疡的延迟愈合伤口或慢性伤口的愈合。

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