摘要:
A cleaning article comprising a melamine foam which comprises a cleaning fluid. Also disclosed a methods for the manufacture of said cleaning articles, and methods for their use in the treatment of hard surfaces.
摘要:
An automatic toilet bowl treatment device, wherein said device comprises: a fluid reservoir, a pump means, a hanger means, and a fluid spray means wherein the entire device is configured so that it can be suspended from, preferably wholly suspended from, a part of a toilet bowl and in particular, a part of the toilet bowl rim. The device is used for the automatic treatment of a lavatory appliance, preferably a toilet bowl and especially preferably the interior surfaces of a toilet bowl which process comprises operating the device to provide a quantity of a treatment composition at periodic intervals to one or more interior surfaces of the lavatory appliance, and preferably to one or more of the interior surfaces of a toilet bowl
摘要:
The present invention provides compositions which not only effectively kill a broad spectrum of microorganisms present on surfaces on contact but continue to kill microorganisms for a period of time thereafter.
摘要:
The present invention relates to a process for the production of improved toilet dispensing devices for use in conjunction with a sanitary appliance particularly a toilet, and methods of using the same.
摘要:
The invention relates to a novel pharmaceutical modified release formulation of guaifenesin and dextromethorphan. The formulation may comprise a hydrophilic polymer, preferably a hydroxypropyl methylcellulose, and a water-insoluble polymer, preferably an acrylic resin, in a ratio range of about one-to-one (1:1) to about nine-to-one (9:1), more preferably a range of about three-to-two (3:2) to about six-to-one (6:1), and most preferably in a range of about two-to-one (2:1) to about four-to-one (4:1) by weight. This formulation capable of providing therapeutically effective bioavailability of guaifenesin for at least twelve hours after dosing in a human subject. The invention also relates to a modified release product which has two portions: a first portion having an immediate release formulation of guaifenesin and a second portion having a sustained release formulation of guaifenesin, wherein one or both portions further comprises dextromethorphan. The modified release product has a maximum guaifenesin serum concentration equivalent to that of an immediate release guaifenesin tablet, and is capable of providing therapeutically effective bioavailability of guaifenesin for at least twelve hours after dosing in a human subject.
摘要:
The invention relates to a novel pharmaceutical sustained release formulation of guaifenesin and at least one additional drug ingredient. The formulation may comprise a hydrophilic polymer, preferably a hydroxypropyl methylcellulose, and a water-insoluble polymer, preferably an acrylic resin, in a ratio range of about one-to-one (1:1) to about nine-to-one (9:1), more preferably a range of about three-to-two (3:2) to about six-to-one (6:1), and most preferably in a range of about two-to-one (2:1) to about four-to-one (4:1) by weight. This formulation capable of providing therapeutically effective bioavailability of guaifenesin for at least twelve hours after dosing in a human subject. The invention also relates to a modified release product which has two portions: a first portion having an immediate release formulation of guaifenesin and a second portion having a sustained release formulation of guaifenesin, wherein one or both portions has at least one additional drug ingredient. The modified release product has a maximum guaifenesin serum concentration equivalent to that of an immediate release guaifenesin tablet, and is capable of providing therapeutically effective bioavailability of guaifenesin for at least twelve hours after dosing in a human subject.
摘要:
A linerless closure mounted on a container, the closure comprising a closure top having a depending sidewall which terminates at a bottom end, the sidewall having an exterior face from which depends a circumferential skirt which extends outwardly from the sidewall having an interior skirt sidewall and an interior top surface which defines a junction space between the exterior face and the skirt, the junction space includes a tapered circumferential sidewall, wherein said closure excludes any flexible or elastomeric intermediate element which is not an integrally molded or formed as a part of the closure, said closure top mounted on a container, the container having a neck, the neck having an outer surface, a top surface and an edge defined by the intersection of the outer surface and the top surface, wherein the neck is in a direct, seal-tight contact with the tapered circumferential sidewall of the cap.
摘要:
A dispensing container comprising a container, and a one-piece closure removably affixed thereto. The one-piece closure includes at least one hinged portion, and at least one stationary portion which are hingedly interconnected, whereby the hinged portion may be temporarily locked into an open configuration at a desired angle relative to the stationary portion to permit for the dispensing of the contents of the container. Alternately the one-piece closure may be removed from the container to permit for the dispensing of the contents of the container, and thereafter the one-piece closure may be returned to reseal the container.