Cleaning Article Comprising Melamine Foam Sponge
    1.
    发明申请
    Cleaning Article Comprising Melamine Foam Sponge 有权
    包含三聚氰胺泡沫海绵的清洁用品

    公开(公告)号:US20120324661A1

    公开(公告)日:2012-12-27

    申请号:US12440498

    申请日:2007-08-10

    IPC分类号: A47L13/17

    CPC分类号: A47L13/17

    摘要: A cleaning article comprising a melamine foam which comprises a cleaning fluid. Also disclosed a methods for the manufacture of said cleaning articles, and methods for their use in the treatment of hard surfaces.

    摘要翻译: 一种包含三聚氰胺泡沫的清洁制品,其包括清洁流体。 还公开了制造所述清洁用品的方法及其用于硬表面处理的方法。

    Automatic Toilet Bowl Treatment Device
    2.
    发明申请
    Automatic Toilet Bowl Treatment Device 有权
    自动马桶处理装置

    公开(公告)号:US20120266920A1

    公开(公告)日:2012-10-25

    申请号:US12447034

    申请日:2008-09-11

    IPC分类号: E03D9/02 B08B9/093

    CPC分类号: E03D9/005 E03D9/032

    摘要: An automatic toilet bowl treatment device, wherein said device comprises: a fluid reservoir, a pump means, a hanger means, and a fluid spray means wherein the entire device is configured so that it can be suspended from, preferably wholly suspended from, a part of a toilet bowl and in particular, a part of the toilet bowl rim. The device is used for the automatic treatment of a lavatory appliance, preferably a toilet bowl and especially preferably the interior surfaces of a toilet bowl which process comprises operating the device to provide a quantity of a treatment composition at periodic intervals to one or more interior surfaces of the lavatory appliance, and preferably to one or more of the interior surfaces of a toilet bowl

    摘要翻译: 一种自动马桶处理装置,其中所述装置包括:流体储存器,泵装置,悬挂装置和流体喷射装置,其中整个装置被构造成使得其可以从优选地完全悬挂在部件上 一个马桶,特别是一个马桶轮圈的一部分。 该装置用于自动处理盥洗室用具,优选地是马桶,特别优选地是马桶的内表面,该方法包括操作该装置,以周期性间隔向一个或多个内表面提供一定数量的处理组合物 并且优选地到马桶的一个或多个内表面

    Sustained release of guaifenesin combination drugs
    6.
    发明授权
    Sustained release of guaifenesin combination drugs 有权
    愈创甘油联合药物的持续释放

    公开(公告)号:US08012504B2

    公开(公告)日:2011-09-06

    申请号:US10413530

    申请日:2003-04-15

    IPC分类号: A61K9/22

    摘要: The invention relates to a novel pharmaceutical modified release formulation of guaifenesin and dextromethorphan. The formulation may comprise a hydrophilic polymer, preferably a hydroxypropyl methylcellulose, and a water-insoluble polymer, preferably an acrylic resin, in a ratio range of about one-to-one (1:1) to about nine-to-one (9:1), more preferably a range of about three-to-two (3:2) to about six-to-one (6:1), and most preferably in a range of about two-to-one (2:1) to about four-to-one (4:1) by weight. This formulation capable of providing therapeutically effective bioavailability of guaifenesin for at least twelve hours after dosing in a human subject. The invention also relates to a modified release product which has two portions: a first portion having an immediate release formulation of guaifenesin and a second portion having a sustained release formulation of guaifenesin, wherein one or both portions further comprises dextromethorphan. The modified release product has a maximum guaifenesin serum concentration equivalent to that of an immediate release guaifenesin tablet, and is capable of providing therapeutically effective bioavailability of guaifenesin for at least twelve hours after dosing in a human subject.

    摘要翻译: 本发明涉及愈创甘油醚和右美沙芬的新型药物改良释放制剂。 制剂可包含亲水性聚合物,优选羟丙基甲基纤维素和水不溶性聚合物,优选丙烯酸树脂,其比例范围为约一对一(1:1)至约九对一(9 :1),更优选约三至二(3:2)至约六对一(6:1)的范围,最优选在约二至一(2:1)的范围内 )至约四对一(4:1)重量比。 该制剂能够在给予人受试者后至少十二个小时提供愈创甘油的治疗有效的生物利用度。 本发明还涉及一种具有两部分的改性释放产物:第一部分具有愈创甘油醚的立即释放制剂,第二部分具有愈创甘油醚的持续释放制剂,其中一个或两个部分还包含右美沙芬。 改性释放产物具有与立即释放愈创甘油醚片剂相当的最大愈创甘油醚血清浓度,并且能够在给予人受试者后至少十二个小时提供愈创甘油的治疗有效的生物利用度。

    Sustained release formulations of guaifenesin and additional drug ingredients
    7.
    发明授权
    Sustained release formulations of guaifenesin and additional drug ingredients 有权
    愈创甘油醚和其他药物成分的缓释制剂

    公开(公告)号:US07985421B2

    公开(公告)日:2011-07-26

    申请号:US11158012

    申请日:2005-06-22

    IPC分类号: A61K9/22

    摘要: The invention relates to a novel pharmaceutical sustained release formulation of guaifenesin and at least one additional drug ingredient. The formulation may comprise a hydrophilic polymer, preferably a hydroxypropyl methylcellulose, and a water-insoluble polymer, preferably an acrylic resin, in a ratio range of about one-to-one (1:1) to about nine-to-one (9:1), more preferably a range of about three-to-two (3:2) to about six-to-one (6:1), and most preferably in a range of about two-to-one (2:1) to about four-to-one (4:1) by weight. This formulation capable of providing therapeutically effective bioavailability of guaifenesin for at least twelve hours after dosing in a human subject. The invention also relates to a modified release product which has two portions: a first portion having an immediate release formulation of guaifenesin and a second portion having a sustained release formulation of guaifenesin, wherein one or both portions has at least one additional drug ingredient. The modified release product has a maximum guaifenesin serum concentration equivalent to that of an immediate release guaifenesin tablet, and is capable of providing therapeutically effective bioavailability of guaifenesin for at least twelve hours after dosing in a human subject.

    摘要翻译: 本发明涉及愈创甘油醚和至少一种另外的药物成分的新型药物缓释制剂。 制剂可包含亲水性聚合物,优选羟丙基甲基纤维素和水不溶性聚合物,优选丙烯酸树脂,其比例范围为约一对一(1:1)至约九对一(9 :1),更优选约三至二(3:2)至约六对一(6:1)的范围,最优选在约二至一(2:1)的范围内 )至约四对一(4:1)重量比。 该制剂能够在给予人受试者后至少十二个小时提供愈创甘油的治疗有效的生物利用度。 本发明还涉及一种具有两部分的改性释放产物:第一部分具有愈创甘油醚的立即释放制剂,第二部分具有愈创甘油醚的缓释制剂,其中一个或两个部分具有至少一种另外的药物成分。 改性释放产物具有与立即释放愈创甘油醚片剂相当的最大愈创甘油醚血清浓度,并且能够在给予人受试者后至少十二个小时提供愈创甘油的治疗有效的生物利用度。

    Linerless closure for a container
    9.
    发明授权
    Linerless closure for a container 有权
    用于容器的无衬封闭

    公开(公告)号:US07891512B2

    公开(公告)日:2011-02-22

    申请号:US11742201

    申请日:2007-04-30

    IPC分类号: B65D53/00

    CPC分类号: B65D41/0428 B65D47/123

    摘要: A linerless closure mounted on a container, the closure comprising a closure top having a depending sidewall which terminates at a bottom end, the sidewall having an exterior face from which depends a circumferential skirt which extends outwardly from the sidewall having an interior skirt sidewall and an interior top surface which defines a junction space between the exterior face and the skirt, the junction space includes a tapered circumferential sidewall, wherein said closure excludes any flexible or elastomeric intermediate element which is not an integrally molded or formed as a part of the closure, said closure top mounted on a container, the container having a neck, the neck having an outer surface, a top surface and an edge defined by the intersection of the outer surface and the top surface, wherein the neck is in a direct, seal-tight contact with the tapered circumferential sidewall of the cap.

    摘要翻译: 一种安装在容器上的无衬封闭件,该封闭件包括封闭顶盖,该顶盖具有终止于底端的悬垂侧壁,该侧壁具有一外表面,该外表面从该侧壁向外延伸,该圆周裙部从侧壁向外延伸, 内部顶部表面限定了外表面和裙部之间的结合空间,所述接合空间包括锥形的周向侧壁,其中所述封闭件不包括任何柔性或弹性体中间元件,所述中间元件不是一体地模制或形成为封闭件的一部分, 所述封闭顶部安装在容器上,所述容器具有颈部,所述颈部具有外表面,顶表面和由所述外表面和所述顶表面的相交限定的边缘,其中所述颈部处于直接密封位置, 与盖的锥形周向侧壁紧密接触。

    Dispensing Container and Closure
    10.
    发明申请
    Dispensing Container and Closure 审中-公开
    分配容器和封闭

    公开(公告)号:US20110011867A1

    公开(公告)日:2011-01-20

    申请号:US12504135

    申请日:2009-07-16

    IPC分类号: B65D45/00 B65D43/16 B67D7/00

    CPC分类号: B65D47/0852

    摘要: A dispensing container comprising a container, and a one-piece closure removably affixed thereto. The one-piece closure includes at least one hinged portion, and at least one stationary portion which are hingedly interconnected, whereby the hinged portion may be temporarily locked into an open configuration at a desired angle relative to the stationary portion to permit for the dispensing of the contents of the container. Alternately the one-piece closure may be removed from the container to permit for the dispensing of the contents of the container, and thereafter the one-piece closure may be returned to reseal the container.

    摘要翻译: 一种分配容器,其包括容器和可拆卸地固定到其上的一体式封闭件。 一体式封闭件包括至少一个铰接部分和至少一个铰接地互连的固定部分,由此铰链部分可以相对于固定部分以期望的角度临时锁定成打开构型,以允许分配 容器的内容。 或者,可以将一体式封闭物从容器中取出以允许容器的内容物的分配,此后可以返回一体式封闭物以重新密封容器。