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公开(公告)号：US20220094133A1
公开(公告)日：2022-03-24
申请号：US17424433
申请日：2020-01-07
发明人： James Morris , David Brooks , Shmuel Gov
摘要： An excimer laser system includes first and second gas cylinders connected to a laser chamber for selectively supplying the laser chamber with gases that are needed to generate and emit laser pulsations having a certain energy level from the laser chamber. At least one of the first and second gas cylinders includes a halogen gas. The halogen gas is consumed during the operation of the excimer laser system. A computer system, included within the excimer laser system, is used to determine whether to resupply the laser chamber with halogen gas from the first and/or second cylinders, or to entirely flush out the gas contents of the laser chamber, and to resupply the flushed gas chamber with gas sourced from the first and/or second cylinders.
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公开(公告)号：US11471695B2
公开(公告)日：2022-10-18
申请号：US14815424
申请日：2015-07-31
发明人： Jeffrey I. Levatter
摘要： A device that is connectable to a phototherapy apparatus for applying targeted phototherapy to an area of skin to place a skin condition into remission and a method of determining a maximum tolerable dose of phototherapy applied to a treatment area to determine an optimum therapeutic dose to quickly place a skin condition into remission. The dosimetry device can include a housing and an optical matrix arranged within the housing. The optical matrix includes a plurality of at least one of absorptive, reflective and/or partially transmissive regions that each permits a different percentage of light to be delivered to an individual's skin. An assessment can then be made as to the maximum tolerable dose of phototherapy that can be applied to the individual's skin in order to place a skin condition into remission.
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公开(公告)号：US20220305282A1
公开(公告)日：2022-09-29
申请号：US17640067
申请日：2020-09-16
发明人： Dolev RAFAELI
IPC分类号： A61N5/06 , A61K31/519 , A61K41/00 , A61N5/067
摘要： Disclosed are methods for localized treatment of a skin condition including administering a therapeutically effective amount of at least one Janus kinase inhibitor (JAKi) to the subject, utilizing a dosimetry device to transmit varying percentages of the UVB light to an area of the subject's skin; assessing a response of the treated area to the varying percentages of the UVB light transmitted thereto; and determining an optimal dose of UVB light, based on the response of the treated area to the varying percentages of UVB light and to the JAKi; and applying the optimal dose of UVB light to the treatment area.
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公开(公告)号：US12005266B2
公开(公告)日：2024-06-11
申请号：US15858524
申请日：2017-12-29
发明人： Jeffrey I. Levatter , David Brooks
CPC分类号： A61N5/0616 , A61N5/062 , A61N2005/0627 , A61N2005/0628 , A61N2005/0644 , A61N2005/0661 , A61N5/067
摘要： A device for applying targeted phototherapy to an area of diseased skin to place a skin condition into remission and a method of determining a maximum tolerable dose of phototherapy applied to a treatment area of diseased skin to determine an optimum therapeutic dose to quickly place a skin condition into remission. The device can include a housing and an optical matrix arranged within the housing that are attached to a dosimetry device. The optical matrix includes a plurality of at least one of absorptive, reflective and/or partially transmissive regions or arrays of perforations that each permits a different percentage of light to be delivered to an individual's skin. Jigs can be included to arrange a plurality of varying exposures to be placed on the patient's skin. An assessment can then be made as to the maximum tolerable dose of phototherapy that can be applied to the individual's skin in order to place a skin condition into remission.
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公开(公告)号：US20220296919A1
公开(公告)日：2022-09-22
申请号：US17640125
申请日：2020-09-16
发明人： Dolev RAFAELI
摘要： Disclosed are methods for localized treatment of a skin condition including administering a therapeutically effective amount of at least one biological drug to the subject, utilizing a dosimetry device to transmit varying percentages of the UVB light to an area of the subject's skin; assessing a response of the treated area to the varying percentages of the UVB light transmitted thereto; and determining an optimal dose of UVB light, based on the response of the treated area to the varying percentages of UVB light and to the biological drug; and applying the optimal dose of UVB light to the treatment area.
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公开(公告)号：US20220288415A1
公开(公告)日：2022-09-15
申请号：US17634079
申请日：2020-08-19
发明人： Shmuel GOV
摘要： A tip section for assembly on a phototherapy apparatus the tip section including a front panel having a proximal surface and a distal surface; and at least two nozzles configured to allow passage of laser radiation therethrough, the at least two nozzles protruding out from a distal surface of the front panel, wherein the at least two nozzles include leading edges at their distal end, that are configured to part hair when combed therethrough; and wherein the at least two nozzles are arranged essentially in parallel one next to another along a major axis thereof.
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