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公开(公告)号：US20060150979A1
公开(公告)日：2006-07-13
申请号：US11298640
申请日：2005-12-08
申请人： Rajiv Doshi , Motohide Hatanaka , Robert Howard
发明人： Rajiv Doshi , Motohide Hatanaka , Robert Howard
CPC分类号： A61M16/06 , A61M15/002 , A61M15/08 , A61M15/085 , A61M16/0616 , A61M16/0683 , A61M16/0688 , A61M16/0694 , A61M16/106 , A61M16/1065 , A61M16/107 , A61M16/20 , A61M16/208 , A61M2210/0618 , A62B23/06
摘要： Described here are methods, devices, and kits for altering the flow of air in a respiratory cavity such as the nostrils of the nose. These methods and devices may be useful for affecting a physiologic benefit in patients suffering from a variety of medical diseases, particularly those that may benefit from “pursed-lip” breathing and non-invasive ventilation, such as COPD, heart failure, sleep apnea, and other medical disorders. The devices are typically removable devices that may be placed over or in a respiratory cavity to increase resistance to airflow within the respiratory cavity. Resistance to expiration may be selectively increased relative to inspiration. Removable nasal devices are described.
摘要翻译： 这里描述了用于改变诸如鼻孔的呼吸腔中的空气流动的方法，装置和试剂盒。 这些方法和装置可用于影响患有各种医学疾病的患者的生理学益处，特别是可能受益于“追求唇”呼吸和非侵入性通气（例如COPD，心力衰竭，睡眠呼吸暂停， 和其他医疗障碍。 这些装置通常是可以放置在呼吸腔内或呼吸腔内的可移除装置，以增加对呼吸腔内的气流的抵抗力。 相对于灵感，耐受性可以有选择地增加。 描述可拆卸的鼻部装置。
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公开(公告)号：US20060150978A1
公开(公告)日：2006-07-13
申请号：US11298362
申请日：2005-12-08
申请人： Rajiv Doshi , Motohide Hatanaka , Robert Howard
发明人： Rajiv Doshi , Motohide Hatanaka , Robert Howard
CPC分类号： A61M16/06 , A61M15/002 , A61M15/08 , A61M15/085 , A61M16/0616 , A61M16/0683 , A61M16/0688 , A61M16/0694 , A61M16/106 , A61M16/1065 , A61M16/107 , A61M16/20 , A61M16/208 , A61M2210/0618 , A62B23/06
摘要： Described here are methods for altering the flow of air in a respiratory cavity such as the nostrils of the nose. These methods and devices may be useful for affecting a physiologic benefit in patients suffering from a variety of medical diseases, particularly those that may benefit from “pursed-lip” breathing and non-invasive ventilation, such as COPD, heart failure, sleep apnea, and other medical disorders. The devices are typically removable devices that may be placed over or in a respiratory cavity to increase resistance to airflow within the respiratory cavity. Resistance to expiration may be selectively increased relative to inspiration. Removable nasal devices are described.
摘要翻译： 这里描述了改变诸如鼻孔的呼吸腔中的空气流动的方法。 这些方法和装置可用于影响患有各种医学疾病的患者的生理学益处，特别是可能受益于“追求唇”呼吸和非侵入性通气（例如COPD，心力衰竭，睡眠呼吸暂停， 和其他医疗障碍。 这些装置通常是可以放置在呼吸腔内或呼吸腔内的可移除装置，以增加对呼吸腔内的气流的抵抗力。 相对于灵感，耐受性可以有选择地增加。 描述可拆卸的鼻部装置。
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公开(公告)号：US08365736B2
公开(公告)日：2013-02-05
申请号：US12884151
申请日：2010-09-16
申请人： Rajiv Doshi , Motohide Hatanaka , Robert A. Howard
发明人： Rajiv Doshi , Motohide Hatanaka , Robert A. Howard
CPC分类号： A61M16/06 , A61M15/002 , A61M15/08 , A61M15/085 , A61M16/0616 , A61M16/0683 , A61M16/0688 , A61M16/0694 , A61M16/106 , A61M16/1065 , A61M16/107 , A61M16/20 , A61M16/208 , A61M2210/0618 , A62B23/06
摘要： Described here are devices for altering the flow of air in a respiratory cavity such as the mouth and nostrils of the nose. These methods and devices may be useful for affecting a physiologic benefit in patients suffering from a variety of medical diseases, particularly those that may benefit from “pursed-lip” breathing and non-invasive ventilation, such as COPD, heart failure, sleep apnea, and other medical disorders. The devices are typically removable devices that may be placed over or in a respiratory cavity to increase resistance to airflow within the respiratory cavity. Resistance to expiration may be selectively increased relative to inspiration. Removable oral and removable nasal devices are described. Oral and nasal devices that filter inhaled airflow of debris and allergens are also provided. A nasal device that increases patency of the nares is also provided.
摘要翻译： 这里描述的是用于改变呼吸腔中的空气流动的装置，例如嘴和鼻孔。 这些方法和装置可用于影响患有各种医学疾病的患者的生理学益处，特别是那些可能受益于唇吸呼吸和非侵入性通气（例如COPD，心力衰竭，睡眠呼吸暂停等）的患者 医疗障碍。 这些装置通常是可以放置在呼吸腔内或呼吸腔内的可移除装置，以增加对呼吸腔内的气流的抵抗力。 相对于灵感，耐受性可以有选择地增加。 描述了可移除的口腔和可移除的鼻装置。 还提供了过滤吸入的碎屑和过敏原气流的口腔和鼻部装置。 还提供了增加鼻孔通畅性的鼻部装置。
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公开(公告)号：US08020700B2
公开(公告)日：2011-09-20
申请号：US12329271
申请日：2008-12-05
申请人： Rajiv Doshi , Bryan Loomas , Enrique F. Mendez , Arthur G. Sandoval , Jeffrey W. Servaites , Matthew Durack
发明人： Rajiv Doshi , Bryan Loomas , Enrique F. Mendez , Arthur G. Sandoval , Jeffrey W. Servaites , Matthew Durack
CPC分类号： B26D3/10 , B26D3/08 , B26F1/02 , B26F1/3846
摘要： Described herein are packaging systems for nasal devices, and methods of packaging and/or dispensing nasal devices. A packaging system may include one or a plurality of nasal devices removably secured to a support backing, and a dispenser. In some variations an applicator may also be included. Methods of using and methods of assembling packaging systems and dispensers are also described.
摘要翻译： 这里描述了用于鼻装置的包装系统，以及包装和/或分配鼻装置的方法。 包装系统可以包括可拆卸地固定到支撑背衬的一个或多个鼻部装置和分配器。 在一些变型中，还可以包括施用器。 还描述了使用方法和组装包装系统和分配器的方法。
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公开(公告)号：US07735491B2
公开(公告)日：2010-06-15
申请号：US11298362
申请日：2005-12-08
申请人： Rajiv Doshi , Motohide Hatanaka , Robert A. Howard
发明人： Rajiv Doshi , Motohide Hatanaka , Robert A. Howard
CPC分类号： A61M16/06 , A61M15/002 , A61M15/08 , A61M15/085 , A61M16/0616 , A61M16/0683 , A61M16/0688 , A61M16/0694 , A61M16/106 , A61M16/1065 , A61M16/107 , A61M16/20 , A61M16/208 , A61M2210/0618 , A62B23/06
摘要： Described here are methods for altering the flow of air in a respiratory cavity such as the nostrils of the nose. These methods and devices may be useful for affecting a physiologic benefit in patients suffering from a variety of medical diseases, particularly those that may benefit from “pursed-lip” breathing and non-invasive ventilation, such as COPD, heart failure, sleep apnea, and other medical disorders. The devices are typically removable devices that may be placed over or in a respiratory cavity to increase resistance to airflow within the respiratory cavity. Resistance to expiration may be selectively increased relative to inspiration. Removable nasal devices are described.
摘要翻译： 这里描述了改变诸如鼻孔的呼吸腔中的空气流动的方法。 这些方法和装置可用于影响患有各种医学疾病的患者的生理学益处，特别是可能受益于“追求唇”呼吸和非侵入性通气（例如COPD，心力衰竭，睡眠呼吸暂停， 和其他医疗障碍。 这些装置通常是可以放置在呼吸腔内或呼吸腔内的可移除装置，以增加对呼吸腔内的气流的抵抗力。 相对于灵感，耐受性可以有选择地增加。 描述可拆卸的鼻部装置。
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公开(公告)号：US20080041373A1
公开(公告)日：2008-02-21
申请号：US11811339
申请日：2007-06-07
申请人： Rajiv Doshi , Bryan Loomas , Ryan Pierce , Elliot Sather , Arthur Sandoval , Jeffrey Servaites , Sandrine Lebas , Matthew Durack
发明人： Rajiv Doshi , Bryan Loomas , Ryan Pierce , Elliot Sather , Arthur Sandoval , Jeffrey Servaites , Sandrine Lebas , Matthew Durack
IPC分类号： A61M15/08
CPC分类号： A62B23/06 , A61F5/08 , A61F5/56 , A61M15/08 , A61M15/085 , A61M16/0616 , A61M16/0688 , A61M16/0866 , A61M16/106 , A61M16/208
摘要： Described herein are adhesive nasal devices. In particular, the adhesive nasal respiratory devices described herein are configured to be worn in communication with a subject's nasal cavity and may include a rim body having a passageway therethrough, an airflow resistor in communication with the passageway of the rim body, and a flexible, adhesive holdfast layer extending outward from the periphery of the rim body. The rim body region may be formed from multiple parts (e.g., a first and a second rim body region), and the airflow resistor may be secured between the parts forming the rim body. Methods of manufacturing and assembling these adhesive nasal devices are also described.
摘要翻译： 这里描述的是粘性鼻装置。 特别地，本文所述的粘合性鼻呼吸器具被配置为与被检者的鼻腔连通，并且可以包括具有通过其的通道的边缘体，与边缘体的通道连通的气流电阻器， 粘合保持层从边缘体的周边向外延伸。 轮辋体区域可以由多个部分（例如，第一和第二边缘体区域）形成，并且气流阻力器可以固定在形成轮辋主体的部件之间。 还描述了制造和组装这些粘合剂鼻装置的方法。
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公开(公告)号：US08291909B2
公开(公告)日：2012-10-23
申请号：US12885366
申请日：2010-09-17
申请人： Rajiv Doshi , Motohide Hatanaka , Robert A. Howard
发明人： Rajiv Doshi , Motohide Hatanaka , Robert A. Howard
CPC分类号： A61M16/06 , A61M15/002 , A61M15/08 , A61M15/085 , A61M16/0616 , A61M16/0683 , A61M16/0688 , A61M16/0694 , A61M16/106 , A61M16/1065 , A61M16/107 , A61M16/20 , A61M16/208 , A61M2210/0618 , A62B23/06
摘要： Described here are devices for altering the flow of air in a respiratory cavity such as the mouth and nostrils of the nose. These methods and devices may be useful for affecting a physiologic benefit in patients suffering from a variety of medical diseases, particularly those that may benefit from “pursed-lip” breathing and non-invasive ventilation, such as COPD, heart failure, sleep apnea, and other medical disorders. The devices are typically removable devices that may be placed over or in a respiratory cavity to increase resistance to airflow within the respiratory cavity. Resistance to expiration may be selectively increased relative to inspiration. Removable oral and removable nasal devices are described. Oral and nasal devices that filter inhaled airflow of debris and allergens are also provided. A nasal device that increases patency of the nares is also provided.
摘要翻译： 这里描述的是用于改变呼吸腔中的空气流动的装置，例如嘴和鼻孔。 这些方法和装置可用于影响患有各种医学疾病的患者的生理学益处，特别是那些可能受益于唇吸呼吸和非侵入性通气（例如COPD，心力衰竭，睡眠呼吸暂停等）的患者 医疗障碍。 这些装置通常是可以放置在呼吸腔内或呼吸腔内的可移除装置，以增加对呼吸腔内的气流的抵抗力。 相对于灵感，耐受性可以有选择地增加。 描述了可移除的口腔和可移除的鼻装置。 还提供了过滤吸入的碎屑和过敏原气流的口腔和鼻部装置。 还提供了增加鼻孔通畅性的鼻部装置。
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公开(公告)号：US07992564B2
公开(公告)日：2011-08-09
申请号：US12711782
申请日：2010-02-24
申请人： Rajiv Doshi , Motohide Hatanaka , Robert A. Howard
发明人： Rajiv Doshi , Motohide Hatanaka , Robert A. Howard
CPC分类号： A61M16/06 , A61M15/002 , A61M15/08 , A61M15/085 , A61M16/0616 , A61M16/0683 , A61M16/0688 , A61M16/0694 , A61M16/106 , A61M16/1065 , A61M16/107 , A61M16/20 , A61M16/208 , A61M2210/0618 , A62B23/06
摘要： Described here are devices for altering the flow of air in a respiratory cavity such as the mouth and nostrils of the nose. These methods and devices may be useful for affecting a physiologic benefit in patients suffering from a variety of medical diseases, particularly those that may benefit from “pursed-lip” breathing and non-invasive ventilation, such as COPD, heart failure, sleep apnea, and other medical disorders. The devices are typically removable devices that may be placed over or in a respiratory cavity to increase resistance to airflow within the respiratory cavity. Resistance to expiration may be selectively increased relative to inspiration. Removable oral and removable nasal devices are described. Oral and nasal devices that filter inhaled airflow of debris and allergens are also provided. A nasal device that increases patency of the nares is also provided.
摘要翻译： 这里描述的是用于改变呼吸腔中的空气流动的装置，例如嘴和鼻孔。 这些方法和装置可用于影响患有各种医学疾病的患者的生理学益处，特别是可能受益于“追求唇”呼吸和非侵入性通气（例如COPD，心力衰竭，睡眠呼吸暂停， 和其他医疗障碍。 这些装置通常是可以放置在呼吸腔内或呼吸腔内的可移除装置，以增加对呼吸腔内的气流的抵抗力。 相对于灵感，耐受性可以有选择地增加。 描述了可移除的口腔和可移除的鼻装置。 还提供了过滤吸入的碎屑和过敏原气流的口腔和鼻部装置。 还提供了增加鼻孔通畅性的鼻部装置。
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公开(公告)号：US07987852B2
公开(公告)日：2011-08-02
申请号：US12369681
申请日：2009-02-11
申请人： Rajiv Doshi , Bryan Loomas , Ryan Kendall Pierce , Elliot Sather , Arthur G. Sandoval , Jeffrey W. Servaites , Sandrine Lebas , Matthew Durack
发明人： Rajiv Doshi , Bryan Loomas , Ryan Kendall Pierce , Elliot Sather , Arthur G. Sandoval , Jeffrey W. Servaites , Sandrine Lebas , Matthew Durack
IPC分类号： A61G10/00
CPC分类号： A62B23/06 , A61F5/08 , A61F5/56 , A61M15/08 , A61M15/085 , A61M16/0616 , A61M16/0688 , A61M16/0866 , A61M16/106 , A61M16/208
摘要： Described herein are adhesive nasal devices. In particular, the adhesive nasal respiratory devices described herein are configured to be worn in communication with a subject's nasal cavity and may include a rim body having a passageway therethrough, an airflow resistor in communication with the passageway of the rim body, and a flexible, adhesive holdfast layer extending outward from the periphery of the rim body. The rim body region may be formed from multiple parts (e.g., a first and a second rim body region), and the airflow resistor may be secured between the parts forming the rim body. Methods of manufacturing and assembling these adhesive nasal devices are also described.
摘要翻译： 这里描述的是粘性鼻装置。 特别地，本文所述的粘合性鼻呼吸器具被配置为与被检者的鼻腔连通，并且可以包括具有通过其的通道的边缘体，与边缘体的通道连通的气流电阻器， 粘合保持层从边缘体的周边向外延伸。 轮辋主体区域可以由多个部分（例如，第一和第二边缘体区域）形成，并且气流阻力器可以固定在形成轮辋主体的部件之间。 还描述了制造和组装这些粘合剂鼻装置的方法。
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公开(公告)号：US07806120B2
公开(公告)日：2010-10-05
申请号：US11811401
申请日：2007-06-07
IPC分类号： F16K31/02 , F15C1/08 , A62B9/00 , A62B7/04 , A62B7/10 , A62B9/02 , A61M16/00 , A61M15/08 , A61G10/00
CPC分类号： A61M15/08 , A61M15/002 , A61M15/085 , A61M2016/0027 , A61M2016/003 , A61M2210/0618
摘要： Described herein are nasal respiratory devices, in particular, nasal respiratory devices configured to achieve positive end-expiratory pressure (PEEP) in a subject wearing the device. PEEP devices may have a threshold pressure for opening during expiration. In some variations, these devices have a threshold pressure for closing during expiration.
摘要翻译： 这里描述的是鼻呼吸装置，特别是构造成在佩戴该装置的受试者中实现呼气末正压（PEEP）的鼻呼吸装置。 PEEP装置可能具有用于在呼气期间打开的阈值压力。 在一些变型中，这些装置具有在到期期间关闭的阈值压力。
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