公开(公告)号：US07941491B2

公开(公告)日：2011-05-10

申请号：US11144428

申请日：2005-06-03

申请人： Manish Chander Sood

发明人： Manish Chander Sood

IPC分类号： G06F15/16

CPC分类号： H04L51/12 ,  H04L51/26

摘要： A method and system that dynamically ranks electronic messages based on their situational and inherent dimensions, which are judged by a set of filters. These filters evaluate the different elemental metadata constituting a message and produce a priority value based on filters relevance and importance. The system iterates through queued messages, examine the structured content for expected attributes, statistically analyze unstructured content, apply dynamically weighted rules and policies to deliver a priority ranking, and then display the message and its vital attributes in accordance with the priority ranking. The system also adaptive learns and adjusts its weighted rules and policies to permit priority ranking to change on real-time or interval-based (may be user-defined) schedule. The system includes a GUI for increasing reading and processing efficiency. The GUI performs supervised and unsupervised learning from the user's behaviors, and displays messages in accordance with their priority classification.

摘要翻译： 一种基于其情境和固有尺寸来动态地排列电子消息的方法和系统，其由一组过滤器判断。 这些过滤器评估构成消息的不同元素元数据，并基于过滤器的相关性和重要性产生优先级值。 系统遍历排队的消息，检查结构化内容以获得预期属性，统计分析非结构化内容，应用动态加权规则和策略提供优先级排序，然后根据优先级排列显示消息及其重要属性。 系统还适应性学习和调整其加权规则和策略，以允许优先级排序以实时或间隔为基础（可能是用户定义的）时间表进行更改。 该系统包括用于增加读取和处理效率的GUI。 GUI根据用户的行为进行监督和无监督学习，并根据其优先级分类显示消息。

公开(公告)号：US07507831B2

公开(公告)日：2009-03-24

申请号：US11329467

申请日：2006-01-11

申请人： Alan P. Kozikowski ,  Werner Tückmantel ,  Leo J. Romanczyk, Jr.

发明人： Alan P. Kozikowski ,  Werner Tückmantel ,  Leo J. Romanczyk, Jr.

IPC分类号： C07D417/12 ,  C07D311/30

CPC分类号： C07D311/62 ,  C07D417/12 ,  C07D417/14

摘要： Various processes are disclosed for preparing protected epicatechin oligomers having (4β,8)-interflavan linkages. In one process, a tetra-O-protected epicatechin monomer or oligomer is coupled with a protected, C-4 activated epicatechin monomer in the presence of an acidic clay such as a mortmorillonite clay. In another process, a 5,7,3′,4′-benzyl protected or a 3 -acetyl-, 5,7,3′,4′-benzyl protected epicatechin or catechin monomer or oligomer is reacted with 3 -O-acetyl-4-[(2-benzothiazolyl)thio]-5,7,3′,4′-tetra-O-benzylepicatechin in the presence of silver tetrafluoroborate. In another process, two 5,7,3′,4′-benzyl protected epicatechin monomers activated with 2-(benzothiazolyl)thio groups at the C-4 positions are cross-coupled in the presence of silver tetrofluoroborate. A process is also disclosed for reacting an unprotected epicatechin or catechin monomer with 4-(benzylthio) epicatechin or catechin. The use of naturally-derived and synthetically-prepared procyanidin (4β,8)4-pentamers to treat cancer is also disclosed.

摘要翻译： 公开了用于制备具有（4beta，8） - 间连环的保护的表儿茶素低聚物的各种方法。 在一个方法中，四氧化物保护的表儿茶素单体或低聚物在保护的C-4活化的表儿茶素单体的存在下，在酸性粘土如失
桑土粘土的存在下偶合。 在另一种方法中，将5,7,3'，4'-苄基保护或3-乙酰基，5,7,3'，4'-苄基保护的表儿茶素或儿茶素单体或低聚物与3-O-乙酰基 -4 - [（2-苯并噻唑基）硫基] -5,7,3'，4'-四-O-苯甲酸酯在四氟硼酸银的存在下反应。 在另一种方法中，在C-4位上用2-（苯并噻唑基）硫基活化的两个5,7,3'，4'-苄基保护的表儿茶素单体在四氟硼酸银的存在下交联。 还公开了使未保护的表儿茶素或儿茶素单体与4-（苄硫基）表儿茶素或儿茶素反应的方法。 还公开了使用天然衍生的和合成制备的原花青素（4beta，8）4-五聚体来治疗癌症。

公开(公告)号：USD576408S1

公开(公告)日：2008-09-09

申请号：US29284406

申请日：2007-09-07

申请人： Sharon Forshpan

设计人： Sharon Forshpan

公开(公告)号：US07409733B2

公开(公告)日：2008-08-12

申请号：US11840353

申请日：2007-08-17

申请人： Douglas Tharalson ,  Diana Tharalson ,  Bruce Martin

发明人： Douglas Tharalson ,  Diana Tharalson ,  Bruce Martin

IPC分类号： A47D13/06 ,  B65D90/00

CPC分类号： A47D15/00 ,  A47D13/06

摘要： A toy storage cover for a portable play yard includes four outer panels shaped to surround the outer walls of the play yard attached at their top edges to four inner panels shaped to line the play yard. A floor panel joins the inner panels and is secured to the floor of the play yard by a mattress pad shaped to fit within the inner panels above the floor of the play yard. A series of pockets are attached to the outer panels of the cover. The pockets have smaller pockets within them or on their outer surfaces. Tie-down straps, fitted foot pockets or attachments through the play yard walls are used to secure the cover to the play yard. The toy storage cover may be adapted to play yards of various designs, cribs or other open topped containers.

摘要翻译： 用于便携式玩具场的玩具储存盖包括四个外板，其形状以围绕其顶部边缘处附接的游戏场地的外壁，四个内部板被成形为使游戏场地排列。 地板镶板连接内板，并通过床垫形成固定​​在场地的地板上，该垫垫形状适合放置在游乐场地板之上的内板内。 一系列口袋连接到外盖的外板上。 口袋内有较小的口袋或其外表面。 用于穿过游乐场围墙的绑带，安装的脚袋或附件可以将盖子固定到游乐场。 玩具储存盖可以适于播放各种设计的场地，婴儿床或其他敞开的顶部容器。

公开(公告)号：US07406725B2

公开(公告)日：2008-08-05

申请号：US11223902

申请日：2005-09-09

申请人： Bruce Martin ,  Sharon Forshpan

发明人： Bruce Martin ,  Sharon Forshpan

IPC分类号： A47D7/00

CPC分类号： A47D7/04 ,  A47C7/029

摘要： A bassinette having a front wall that may selectively be set at a height substantially equal to the height of other walls of the bassinette, or alternatively released to allow the front wall to have a lower height than remaining walls, wherein the method of attachment of a cross-member supporting the top edge comprises receiver cups, and a retractable tongue to allow the cross-member to be selectively trapped between the receiver cups, in a manner requiring only a single hand for insertion and removal of the cross-member from the structure of the bassinette.

摘要翻译： 具有可以有选择地将其设置在高度大致等于或低于其它墙壁的高度的高音箱的高度的前壁的轻便筒，或者替代地释放以允许前壁具有比其余壁更低的高度，其中， 支撑顶部边缘的横向构件包括接收器杯和可缩回的舌部，以允许横向构件被选择性地捕获在接收器杯之间，仅需要单手来从构件插入和移除横向构件 的bassinette。

公开(公告)号：US07244855B2

公开(公告)日：2007-07-17

申请号：US10481729

申请日：2003-10-02

申请人： Alan P. Kozikowski ,  Werner Tückmantel ,  Leo J. Romanczyk, Jr. ,  Xingquan Ma

发明人： Alan P. Kozikowski ,  Werner Tückmantel ,  Leo J. Romanczyk, Jr. ,  Xingquan Ma

IPC分类号： C07D311/00

CPC分类号： C07D311/62 ,  C07D417/12 ,  C07D417/14

摘要： Various processes are disclosed for preparing procyanidin oligomers having (4,8)-interflavan linkages. In an improved process, a tetra-O-protected-epicatechin or -catechin monomer or oligomer is coupled with a protected, C-4 alkoxy-activated-epicatechin or -catechin monomer in the presence of an acidic clay instead of a Lewis acid. In a second process, a 5,7,3′,4′-tetra-O-protected or preferably penta-O-protected-epicatechin or -catechin monomer or oligomer is reacted with a tetra-O-protected or preferably penta-O-protected-epicatechin or -catechin monomer having a thio activating group at the C-4 position; the coupling is carried out in the presence of silver tetrafluoroborate. In third process, two molecules of a penta-O-protected-epicatechin or -catechin monomer activated with a 2-(benzothiazolyl)thio group at the C-4 position are self-condensed in the presence of silver tetrafluoroborate. An improved two-step process for preparing a C-4 alkoxy activated tetra-O-benzyl-protected, 8-bromo-blocked-epicatechin or -catechin monomer is also provided. The use of naturally-derived and synthetically-prepared procyanidin (4β,8)4-pentamers to treat cancer is also disclosed.

摘要翻译： 公开了用于制备具有（4,8） - 连续黄烷键的原花青素低聚物的各种方法。 在改进的方法中，在酸性粘土代替路易斯酸的情况下，将四-O-保护的表儿茶素或儿茶素单体或低聚物与受保护的C-4烷氧基 - 表儿茶素或儿茶素单体偶合。 在第二种方法中，5,7,3'，4'-四-O-保护的或优选五-O-保护的表儿茶素或儿茶素单体或低聚物与四-O-保护的或优选五-O 在C-4位具有硫代活化基团的保护表儿茶素或儿茶素单体; 在四氟硼酸银的存在下进行偶合。 在第三种方法中，在四氟硼酸银存在下，用2-（苯并噻唑基）硫基在C-4位上活化的五分子保护的表儿茶素或儿茶素单体的两分子是自缩合的。 还提供了一种用于制备C-4烷氧基活化的四-O-苄基保护的8-溴封闭的表儿茶素或儿茶素单体的改进的两步法。 还公开了使用天然衍生的和合成制备的原花青素（4beta，8）4质子以治疗癌症。

公开(公告)号：US07415739B2

公开(公告)日：2008-08-26

申请号：US11209401

申请日：2005-08-22

申请人： Douglas Tharalson ,  Diana Tharalson ,  Bruce Martin

发明人： Douglas Tharalson ,  Diana Tharalson ,  Bruce Martin

IPC分类号： A47D7/04

CPC分类号： A47D7/002 ,  A47D5/00 ,  A47D7/04 ,  A47D9/005

摘要： A co-sleeper convertibly adapted for use as a changing table is described. The invention includes a collapsible rigid frame designed to support an enclosure at a predetermined height. The enclosure has padded walls and is sized and shaped to fit over the rigid frame. The back, first and second side walls of the enclosure are of a first height above a floor of the enclosure while the front wall is of a lower height. The floor of the enclosure is designed to be slightly lower that the top surface of a parental bed. A mattress pad is sized and shaped to fit within the enclosure and is segmented to use as a containing cover for the co-sleeper when the frame is collapsed. A strapping member is provided to hold the co-sleeper to the parental bed. A number of variations of this strapping member are provided. Several styles of support members for the enclosure are provided. These include support bars that attach to the rigid frame, a series of hangers that support horizontal bars while hanging from top rails of the frame, and rigid panels and support rods fitted into pockets on the underside of the enclosure. Variants on the invention also include mesh panels for lower portions of the enclosure walls and rigid panels for insertion into pockets in the enclosure walls designed to prevent the formation of unwanted folds in the enclosure walls that could trap a child. The co-sleeper is height adjustable for variations in parental bed height.

摘要翻译： 描述可转换地用作变更表的共轨枕床。 本发明包括可折叠的刚性框架，其设计成在预定高度上支撑外壳。 外壳具有填充墙壁，并且其尺寸和形状适于装配在刚性框架上。 外壳的背部，第一和第二侧壁在外壳的地板上方具有第一高度，而前壁具有较低的高度。 外壳的地板设计成比父母床的顶面略低。 床垫的尺寸和形状适于装配在外壳内，并且当框架被折叠时被分段以用作共轨枕的容纳盖。 提供捆扎构件以将共轨枕保持在母床上。 提供了该捆扎件的多种变型。 提供了几种型号的外壳支撑构件。 这些包括连接到刚性框架的支撑杆，一系列悬挂器，其在从框架的顶部轨道悬挂的同时支撑水平杆，以及刚性面板和安装在外壳下侧的凹穴中的支撑杆。 本发明的变型还包括用于封闭壁的下部的网板和用于插入到外壳壁中的凹槽中的刚性面板，其设计成防止在可能陷入小孩的外壳壁中形成不想要的折痕。 共卧床的高度是可调节的，用于父母床高度的变化。

公开(公告)号：US07395960B1

公开(公告)日：2008-07-08

申请号：US09481577

申请日：2000-01-12

申请人： Glenn R. Toothman, III ,  Ravinder P. Chandhok ,  Kimberly H. Chandhok

发明人： Glenn R. Toothman, III ,  Ravinder P. Chandhok ,  Kimberly H. Chandhok

IPC分类号： G06K5/00

CPC分类号： G06K17/0022

摘要： Systems and methods of using the systems for delivering information related to a remote location to individuals at the remote location are disclosed. The system comprises a memory device affixed to a physical object at the remote location, the information related to the remote location residing on the memory device, and a portable memory reading device, separate from the memory device, that retrieves the information from the memory device when positioned at the remote location and communicates the information to a party located at the remote location. The system may further comprise a database wherein the information residing on the memory device is replicated and the database can be accessed by a user of the system via a suitable communications medium or combination of mediums. The system may also comprise a portable memory reading device having a GPS receiver positioned at a remote location and a database, such that the GPS coordinates of the remote location are determined by the portable memory reading device and communicated to the database over a communications link, and the database communicates the information related to the remote location back to the portable memory reading device over the communications link.

摘要翻译： 公开了将系统用于将与远程位置相关的信息传递给远程位置处的个人的系统和方法。 该系统包括固定到远程位置处的物理对象的存储装置，与驻留在存储装置上的远程位置有关的信息以及与存储装置分离的便携式存储器读取装置，其从存储装置检索信息 当位于远程位置并将信息传送到位于远程位置的一方时。 系统还可以包括数据库，其中存储在存储器设备上的信息被复制，并且数据库可以由系统的用户经由合适的通信介质或介质的组合来访问。 该系统还可以包括具有位于远程位置的GPS接收器和数据库的便携式存储器读取装置，使得远程位置的GPS坐标由便携式存储器读取装置确定并通过通信链路传送到数据库， 并且数据库通过通信链路将与远程位置相关的信息传送回便携式存储器读取装置。

公开(公告)号：US07304913B2

公开(公告)日：2007-12-04

申请号：US11187727

申请日：2005-07-22

申请人： Mark A. Niemiec ,  Louis M. Heidelberger

发明人： Mark A. Niemiec ,  Louis M. Heidelberger

IPC分类号： G04B47/00 ,  G08B13/14

CPC分类号： G06Q50/22 ,  A61B5/0002 ,  A61J1/035 ,  A61J7/0436 ,  A61J7/0454 ,  A61J7/0481 ,  A61J2200/30 ,  A61J2200/72 ,  A61J2205/60 ,  A61J2205/70 ,  G06F19/00 ,  G06F19/3462 ,  G06Q10/083 ,  G06Q10/087 ,  G06Q50/24 ,  G08B13/1427 ,  G08B21/0261 ,  G08B21/24 ,  G16H40/20 ,  H01H3/141 ,  H02M7/003 ,  H05K1/0293

摘要： The present invention relates to assisting patients in the taking of medication, and to assisting third parties in accumulating information regarding patient medication intake. The invention may be embodied a system including a portable medication monitor used in association with an instrumented medication package to provide intake data acquisition and patient support functions. The system may further be connected to a computer or computer network allowing information distribution between the medication monitor and third parties, such as physicians or pharmacists.

摘要翻译： 本发明涉及协助患者服用药物，并协助第三方积累关于患者药物摄入的信息。 本发明可以体现为一种包括便携式药物监测器的系统，该便携式药物监测器与用于提供进气数据采集和患者支持功能的仪表化药物包相结合使用 系统还可以连接到计算机或计算机网络，从而允许药物监测器和第三方之间的信息分布，诸如医生或药剂师。

公开(公告)号：US07268240B2

公开(公告)日：2007-09-11

申请号：US10858449

申请日：2004-05-28

申请人： Leo J. Romanczyk, Jr. ,  Alan P. Kozikowski ,  Werner Tueckmantel ,  Marc E. Lippman

发明人： Leo J. Romanczyk, Jr. ,  Alan P. Kozikowski ,  Werner Tueckmantel ,  Marc E. Lippman

IPC分类号： C07D311/62

CPC分类号： C07H17/06 ,  A61K31/35 ,  C07D311/32 ,  C07D311/60 ,  C07D311/62

摘要： A process is disclosed for the production of polyphenol oligomers having n polyphenol monomeric units, n being an integer from 2-18. The process includes coupling of a protected polyphenol, having protected phenolic hydroxyl groups, with a C-4 functionalized polyphenol monomer. The protected polyphenol may be a protected polyphenol monomer or a protected polyphenol oligomer having 2-17 monomeric units. Advantageously, polyphenol monomeric units forming the polyphenol oligomers may be the same or different flavanoid compounds.

摘要翻译： 公开了用于生产具有多酚单体单元的多酚低聚物的方法，n为2-18的整数。 该方法包括将被保护的酚羟基的被保护的多酚与C-4官能化的多酚单体的偶联。 受保护的多酚可以是受保护的多酚单体或具有2-17单体单元的被保护的多酚低聚物。 有利地，形成多酚低聚物的多酚单体单元可以是相同或不同的类黄酮化合物。