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公开(公告)号：US12114868B2
公开(公告)日：2024-10-15
申请号：US17929873
申请日：2022-09-06
发明人： Sang-Eun Song , Pradipta Biswas
CPC分类号： A61B17/142 , A61B17/32002 , A61B34/30 , A61F2/28 , A61F2/4601 , A61F2/4644 , A61B2017/320032 , A61F2002/4645 , A61F2002/4649
摘要： Systems and methods are disclosed for harvesting tissue from a donor site. Exemplary embodiments include a first and second conduit through which a flexible saw component is guided. Certain embodiments include a mechanism which facilitates insertion of the flexible cutting member component parallel to the transverse plane and slicing the graft parallel to the coronal plane to extract the graft.
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公开(公告)号：US12109271B2
公开(公告)日：2024-10-08
申请号：US17257731
申请日：2019-07-03
IPC分类号： A61K47/59 , A61K31/203 , A61K31/436 , A61K31/593 , A61K38/18 , A61K38/19 , A61K38/20 , A61K39/00 , A61P25/00
CPC分类号： A61K47/593 , A61K31/203 , A61K31/436 , A61K31/593 , A61K38/1841 , A61K38/1866 , A61K38/193 , A61K38/2066 , A61K39/0008 , A61P25/00
摘要： Provided are a dual microparticle system to treat Multiple Sclerosis, the system comprising phagocytosable and non-phagocytosable microparticles for delivery of at least one antigen, at least one immunomodulatory agent, at least one immunosuppressive agent and at least one chemoattractant to a subject suffering from Multiple Sclerosis to generate tolerogenic dendritic cells in the subject and treat the Multiple Sclerosis.
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公开(公告)号：US12089882B2
公开(公告)日：2024-09-17
申请号：US16864001
申请日：2020-04-30
CPC分类号： A61B17/8052 , A61B17/8076 , A61B17/82
摘要： A modular system is provided for assembling a structure to secure to opposite sides of a fracture in a bone of a subject. The modular system includes a plate with a perimeter including a plurality of openings. The perimeter defines an interior area within the plate. The modular system also includes a link with one or more openings along a linear axis defining the link. The one or more openings of the link include a connector to receive a fastener to be secured in the bone. The plurality of openings of the plate includes a first opening with an inner diameter configured to removably receive an outer diameter of the connector of the link so that the link is rotatably received within the first opening. A method is also provided for assembling the structure using the modular system and securing the assembled structure to opposite sides of the bone fracture.
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公开(公告)号：US12078197B1
公开(公告)日：2024-09-03
申请号：US18416324
申请日：2024-01-18
申请人： Henry Wang , Ralph Bagnall
发明人： Henry Wang , Ralph Bagnall
CPC分类号： F16B2/14 , F16B37/042 , F16B13/0858 , F16B2200/10 , F16B2200/30 , F16B2200/406 , F16B2200/99
摘要： An apparatus (100), including: a hub (102) having a hub center (160); a securing mechanism (106) configured to fix the hub onto a flat surface; and an eccentric clamp disk (104). When the hub is fixed to the flat surface and nested in the eccentric clamp disk, an interlocking slip fit relationship exists between the hub and the eccentric clamp disk. The interlocking slip fit relationship enables infinite rotation of the eccentric clamp disk about the hub center and has a geometric interlock (170). The geometric interlock is configured so that when the eccentric clamp disk is pushed laterally into contact with the hub, the geometric interlock urges the eccentric clamp disk downward onto the flat surface.
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公开(公告)号：US12074595B2
公开(公告)日：2024-08-27
申请号：US17679047
申请日：2022-02-23
IPC分类号： H03K17/968 , H04B10/69
CPC分类号： H03K17/968 , H04B10/69
摘要： This Orthogonal Code Readout (OCR) electronically expands the dynamic range of CMOS active pixels by adding digital electron wells. The dynamic range of an active pixel is not limited by in-pixel capacitance. When employed as a thermal array readout, OCR simplifies thermal detector array fabrication by eliminating the need for large electron well capacitors. OCR also improves digital quantization beyond that provided by hardware digitizers.
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公开(公告)号：US12072102B2
公开(公告)日：2024-08-27
申请号：US18128589
申请日：2023-03-30
发明人： Mats Andersson , Rickard Heinefeldt , Olle Lindman , Magnus Persson , Patrik Jaerling , Atanu Kumar Kundu
IPC分类号： F23R3/28
CPC分类号： F23R3/28
摘要： A fuel nozzle for use in a combustion arrangement of a gas turbine includes a main body extending from a cold side to an opposite hot side and at least five air passages arranged next to each other extending from the cold side towards the hot side. A fuel distribution chamber is arranged within the main body next to the cold side, wherein the air passages cross the fuel distribution chamber separated by passage walls. To inject fuel into the air passages, fuel holes are arranged within the passage walls.
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公开(公告)号：US12070304B2
公开(公告)日：2024-08-27
申请号：US16964736
申请日：2019-01-24
发明人： Amal Isaiah , Jeffrey S. Wolf , Stephen Restaino
CPC分类号： A61B5/0826 , A61B5/14542 , A61B5/4818 , A61B5/4836 , A61B5/6822 , A61B5/7405 , A61B5/742 , A61B5/7455 , A61N7/00 , A61N2007/0026 , A61N2007/0052 , A61N2007/0073
摘要： A method and system detects a hypoxic condition during an obstruction of an airway of a subject to detect and treat obstructive sleep apnea (OSA) in the subject. The method and system includes an organ stimulating transducer configured for placement in a vicinity of an organ of the subject to stimulate the organ and remove the obstruction when OSA is detected.
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公开(公告)号：US12070031B2
公开(公告)日：2024-08-27
申请号：US17024195
申请日：2020-09-17
摘要： Compositions and methods for systemic delivery of at least one cargo in a vascular plant. Compositions may include at least one cargo delivery particle, having a core and a shell; and at least one cargo disposed on the shell. The core may include at least one micronutrient. The shell may include a coating material. The at least one cargo delivery particle may have a size of less than about 10 nanometers. Methods may include administering an effective amount of the compositions to a plant.
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公开(公告)号：US12067154B2
公开(公告)日：2024-08-20
申请号：US17274179
申请日：2019-09-16
发明人： Jerry Fornander , Andreas Graichen , Thomas Jetzfellner , Johan Lindstam , Markus Sauer , Monika Sturm
IPC分类号： G06F16/23 , B22F10/80 , B22F12/90 , B33Y50/00 , G06F16/60 , G06F16/64 , G06F21/60 , G06F21/64 , G06F21/78
CPC分类号： G06F21/78 , B22F10/80 , B22F12/90 , B33Y50/00 , G06F16/2379 , G06F21/602 , G06F21/64
摘要： A sensor data assembly providing a secured data storage for monitored data containing sensor data acquired by at least one sensor, a processing unit adapted to provide a cryptographic checksum of the monitored data and/or the sensor data acquired by the sensor, a distributed database and a first connection adapted to, at least temporarily, connect the sensor and the processing unit. A method provides manipulation proof monitored data containing sensor data of a sensor of the sensor data assembly.
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公开(公告)号：US12037919B2
公开(公告)日：2024-07-16
申请号：US18024227
申请日：2021-08-31
发明人： Otto Jörgensson , Saeid Kharazmi , Johan Kling
CPC分类号： F01D5/066 , F01D5/081 , F01D5/087 , F05D2220/32
摘要： A rotor assembly, especially for a gas turbine, includes at least a first rotor disc and a second rotor disc, the two rotor discs are arranged directly next to each other. The first rotor disc has a center through hole and the second rotor disc has no center through hole but a rotor disc center. A flow restrictor assembly which restricts the effective flow cross section of the center through hole of the first disc is used to control or to adjust the cooling air through gaps of a form-fitting torque transmitting device.
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