AN INJECTOR COMPRISING A SAFETY PIN
    1.
    发明申请

    公开(公告)号:US20180185582A1

    公开(公告)日:2018-07-05

    申请号:US15736337

    申请日:2016-07-11

    申请人: ALK-Abelló A/S

    发明人: Jens MIKKELSEN

    IPC分类号: A61M5/20

    摘要: An injector is provided for performing an injection operation comprising a housing (104), a needle extendable from a front end of the housing, a rear end of the housing and a longitudinal axis extending between the front end and the rear end, a safety pin (116) in an actuation locked position coupled to the housing and moveable to a safety released position coupled to the housing. The injector is locked against actuation when the safety pin is in the actuation locked position and the injector is ready for actuation of the injection operation when the safety pin is in the safety released position.

    Injector comprising a safety pin
    3.
    发明授权

    公开(公告)号:US11020527B2

    公开(公告)日:2021-06-01

    申请号:US15736337

    申请日:2016-07-11

    申请人: ALK-Abelló A/S

    发明人: Jens Mikkelsen

    IPC分类号: A61M5/20 A61M5/32

    摘要: An injector is provided for performing an injection operation comprising a housing (104), a needle extendable from a front end of the housing, a rear end of the housing and a longitudinal axis extending between the front end and the rear end, a safety pin (116) in an actuation locked position coupled to the housing and moveable to a safety released position coupled to the housing. The injector is locked against actuation when the safety pin is in the actuation locked position and the injector is ready for actuation of the injection operation when the safety pin is in the safety released position.

    METHOD FOR QUANTIFICATION OF ALLERGENS
    7.
    发明申请
    METHOD FOR QUANTIFICATION OF ALLERGENS 审中-公开
    过敏原定量方法

    公开(公告)号:US20140206027A1

    公开(公告)日:2014-07-24

    申请号:US14198112

    申请日:2014-03-05

    申请人: ALK-Abelló A/S

    发明人: Ulla Seppälä

    IPC分类号: C12Q1/37

    摘要: The invention relates to method for quantification of the absolute amount of allergen in an allergen sample comprising: a) providing a known amount of one or more allergen calibration standard peptide(s) having a sequence of amino acids which is identical with, and optionally unique for, a sequence to be found in the allergen to be quantified and optionally labelling said allergen calibration standard peptide(s), b) degrading the allergen sample to obtain a mixture of peptides, and optionally labelling said peptides with one or more labelling agent(s), wherein at least the peptides in the degraded allergen sample or the calibration standard peptides are labelled, and if both the peptides in the degraded allergen sample and the allergen calibration standard peptide(s) are labelled, the labelling agent(s) used for labelling the allergen calibration standard peptide(s) are different from the labelling agent(s) used for labelling the peptides of the degraded allergen sample, c) quantifying the absolute amount of allergen by correlating the amount of the allergen calibration standard peptide(s) with the amount of the corresponding peptide(s) of the degraded allergen sample by mass analysis.

    摘要翻译: 本发明涉及定量变应原样品中过敏原绝对量的方法,其包括:a)提供已知量的一种或多种变应原校准标准肽,其具有与SEQ ID NO: 用于,要在量变的变应原中发现的序列,并任选地标记所述变应原校准标准肽,b)降解变应原样品以获得肽的混合物,并任选地用一种或多种标记试剂标记所述肽( s),其中至少降解的变应原样品中的肽或标准标准肽被标记,并且如果降解过敏原样品中的肽和变应原校准标准肽都被标记,则使用标记试剂 用于标记变应原校准标准肽不同于用于标记降解过敏原样品的肽的标记试剂,c)量化 通过质量分析将变应原校准标准肽的量与降解过的变应原样品的相应肽的量相关联来确定过敏原的绝对量。

    Method for quantification of allergens

    公开(公告)号:US10023900B2

    公开(公告)日:2018-07-17

    申请号:US14198112

    申请日:2014-03-05

    申请人: ALK-Abelló A/S

    发明人: Ulla Seppälä

    摘要: The invention relates to method for quantification of the absolute amount of allergen in an allergen sample comprising: a) providing a known amount of one or more allergen calibration standard peptide(s) having a sequence of amino acids which is identical with, and optionally unique for, a sequence to be found in the allergen to be quantified and optionally labelling said allergen calibration standard peptide(s), b) degrading the allergen sample to obtain a mixture of peptides, and optionally labelling said peptides with one or more labelling agent(s), wherein at least the peptides in the degraded allergen sample or the calibration standard peptides are labelled, and if both the peptides in the degraded allergen sample and the allergen calibration standard peptide(s) are labelled, the labelling agent(s) used for labelling the allergen calibration standard peptide(s) are different from the labelling agent(s) used for labelling the peptides of the degraded allergen sample, c) quantifying the absolute amount of allergen by correlating the amount of the allergen calibration standard peptide(s) with the amount of the corresponding peptide(s) of the degraded allergen sample by mass analysis.