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1.发明授权Low-coherence interferometry and optical coherence tomography for image-guided surgical treatment of solid tumors 有权低相干干涉测量和光学相干断层扫描用于实体瘤的图像引导手术治疗公开(公告)号：US08983580B2
公开(公告)日：2015-03-17
申请号：US12040415
申请日：2008-02-29
CPC分类号： A61B5/0066 , A61B5/0073 , A61B5/415 , A61B5/418 , A61B5/6852 , A61B5/6853 , A61B5/7257 , A61B2562/0238
摘要： A method of forming an image of tissue. The method includes beginning an invasive procedure on a patient exposing tissue. The method then includes acquiring OCT data from the exposed tissue and converting the OCT data into at least one image. The method also includes ending the invasive procedure after the converting of the data.
摘要翻译： 一种形成组织图像的方法。 该方法包括在暴露组织的患者身上开始侵入性手术。 该方法然后包括从暴露的组织获取OCT数据并将OCT数据转换成至少一个图像。 该方法还包括在转换数据之后终止侵入性过程。
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公开(公告)号：US07787129B2
公开(公告)日：2010-08-31
申请号：US11669561
申请日：2007-01-31
申请人： Adam M. Zysk , Steven G. Adie , Matthew S. Leigh , Julian J. Armstrong , David D. Sampson , Stephen A. Boppart
发明人： Adam M. Zysk , Steven G. Adie , Matthew S. Leigh , Julian J. Armstrong , David D. Sampson , Stephen A. Boppart
IPC分类号： G01B9/02
CPC分类号： A61B5/0084 , A61B5/0066 , A61B5/0091 , A61B5/6848 , A61B10/0233
摘要： A method of analyzing tissue includes inserting a radiation source into tissue, impinging radiation upon the tissue, obtaining a sample signal of the radiation that impinges upon the tissue, and determining a refractive index of the tissue from the sample signal. The method may also include determining at least one other optical property of the tissue. The method may provide for identifying tissue as part of a biopsy method. A device for analyzing tissue may include a low-coherence interferometer and a probe optically coupled to the interferometer, where the probe includes a radiation source.
摘要翻译： 分析组织的方法包括将辐射源插入到组织中，将辐射照射到组织上，获得撞击在组织上的辐射的样本信号，以及从样本信号确定组织的折射率。 该方法还可以包括确定组织的至少一个其它光学性质。 该方法可以提供识别组织作为活检方法的一部分。 用于分析组织的装置可以包括低相干干涉仪和光学耦合到干涉仪的探针，其中探针包括辐射源。
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3.发明授权公开(公告)号：US08218152B1
公开(公告)日：2012-07-10
申请号：US12326974
申请日：2008-12-03
IPC分类号： G01B11/02
CPC分类号： A61B5/0068 , A61B5/0075 , G01B9/02091 , G01N21/45 , G01N2021/1787 , G02B21/0056
摘要： A system and method for microscale measurement and imaging of the group refractive index of a sample. The method utilizes a broadband confocal high-numerical aperture microscope embedded into an interferometer and a spectrometric means, whereby spectral interferograms are analyzed to compute optical path delay of the beam traversing the sample as the sample is translated through the focus of an interrogating light beam. A determination of group refractive index may serve to disambiguate phase ambiguity in a measurement of refractive index at a specified wavelength. Spatial resolution of object characterization in three dimensions is achieved by imaging the object from multiple viewpoints.
摘要翻译： 用于样品的组折射率的微观测量和成像的系统和方法。 该方法利用嵌入干涉仪和光谱测量装置的宽带共焦高数值孔径显微镜，分析光谱干涉图以计算当样品通过询问光束的焦点平移时穿过样品的光束的光程延迟。 组折射率的确定可以用于消除在特定波长处的折射率测量中的相位模糊度。 通过从多个视点对对象进行成像，实现三维对象表征的空间分辨率。
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4.发明申请LOW-COHERENCE INTERFEROMETRY AND OPTICAL COHERENCE TOMOGRAPHY FOR IMAGE-GUIDED SURGICAL TREATMENT OF SOLID TUMORS 有权用于图像引导的固体肿瘤外科治疗的低相干干涉和光学相干平衡公开(公告)号：US20090221920A1
公开(公告)日：2009-09-03
申请号：US12040415
申请日：2008-02-29
CPC分类号： A61B5/0066 , A61B5/0073 , A61B5/415 , A61B5/418 , A61B5/6852 , A61B5/6853 , A61B5/7257 , A61B2562/0238
摘要： A method of forming an image of tissue. The method includes beginning an invasive procedure on a patient exposing tissue. The method then includes acquiring OCT data from the exposed tissue and converting the OCT data into at least one image. The method also includes ending the invasive procedure after the converting of the data.
摘要翻译： 一种形成组织图像的方法。 该方法包括在暴露组织的患者身上开始侵入性手术。 该方法然后包括从暴露的组织获取OCT数据并将OCT数据转换成至少一个图像。 该方法还包括在转换数据之后终止侵入性过程。
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