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    Post irradiation shelf-stable dual paste direct injectable bone cement precursor systems and methods of making same
    1.
    发明授权
    Post irradiation shelf-stable dual paste direct injectable bone cement precursor systems and methods of making same 有权
    后照射货架稳定双膏直接注射骨水泥前体体系及其制备方法

    公开(公告)号：US08481065B2

    公开(公告)日：2013-07-09

    申请号：US12970393

    申请日：2010-12-16

    申请人： Donal O'Mahony ,  Venkat R. Garigapati ,  Adrian Sun Wai ,  Brian Hess ,  Matthew E. Murphy

    发明人： Donal O'Mahony ,  Venkat R. Garigapati ,  Adrian Sun Wai ,  Brian Hess ,  Matthew E. Murphy

    IPC分类号： A61F2/00 ,  A61F2/28 ,  A61L24/00 ,  A61L24/02 ,  A61L24/04

    CPC分类号： A61L24/06 ,  A61L24/001 ,  A61L24/02 ,  A61L27/12 ,  A61L27/50 ,  A61L2430/02

    摘要： The present invention relates to a bone cement precursor system that is presented in the form of two shelf-stable pastes which have been terminally sterilized and are held in separate containers during product transport and storage. When the product is used during surgery, these pastes inject to a site of application through a static mixing device by the action of applied injection force. When the two pastes are mixed, they start to react to each other while injecting out. The resulting composition is highly biocompatible, osteoconductive, injectable, rapid setting and bioresorbable, and is useful in connection with bone repair procedures, for example, in the craniomaxillofacial, trauma and orthopedic areas.

    摘要翻译： 本发明涉及一种骨水泥前体体系，其以两种储存稳定的糊状物的形式存在，这些浆料已被终止灭菌，并在产品运输和储存期间保持在分开的容器中。 当在手术中使用该产品时，这些糊剂通过施加注射力的作用通过静态混合装置注射到施用部位。 当两种糊料混合时，它们在注射时开始彼此反应。 所得组合物具有高生物相容性，骨诱导性，可注射，快速凝固和生物可再吸收，并且可用于骨修复程序，例如颅颌面，创伤和矫形区域。

    Injectable calcium phosphate cement
    5.
    发明授权
    Injectable calcium phosphate cement 有权
    可注射磷酸钙水泥

    公开(公告)号：US07892346B2

    公开(公告)日：2011-02-22

    申请号：US12290225

    申请日：2008-10-28

    申请人： Gerard M. Insley ,  Adrian Sun Wai ,  Donal O'Mahony ,  Paul Higham

    发明人： Gerard M. Insley ,  Adrian Sun Wai ,  Donal O'Mahony ,  Paul Higham

    IPC分类号： C04B12/02

    CPC分类号： A61L27/12 ,  A61L24/02 ,  A61L27/02 ,  A61L2430/02

    摘要： The invention is related to a premixed putty calcium phosphate composition comprising at least two calcium phosphate minerals, at least one reaction retarding agent, at least one binding agent, at least one sodium phosphate, and at least one nonaqueous extender, wherein one of said at least two calcium phosphate minerals contains a stabilizing agent.

    摘要翻译： 本发明涉及包含至少两种磷酸钙矿物，至少一种反应延迟剂，至少一种结合剂，至少一种磷酸钠和至少一种非水性增量剂的预混合腻子磷酸钙组合物，其中所述 至少两种磷酸钙矿物质含有稳定剂。