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公开(公告)号：US20240156876A1
公开(公告)日：2024-05-16
申请号：US18381439
申请日：2023-10-18
发明人： Thomas Repstad , Finn Myhren , Nils Hoem
IPC分类号： A61K35/612 , A61K9/107 , A61K31/202
CPC分类号： A61K35/612 , A61K9/107 , A61K31/202
摘要： The present invention relates to compositions comprising phospholipids for delivery of bioactive compounds such as ethyl esters, fish oil concentrates, cannabinoids, and curcumin under conditions such the bioavailability of the bioactive compounds is enhanced.
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公开(公告)号：US11744864B2
公开(公告)日：2023-09-05
申请号：US17218760
申请日：2021-03-31
发明人： Finn Myhren , Petter-Arnt Hals , Nils Hoem , Andreas Berg Storsve , Papasani V. Subbaiah , Poorna Yalagala , Sugasini Dhavamani , Leon Tai
IPC分类号： A61P27/02 , A61K9/00 , A61K31/047 , A61K31/122 , A61K31/685 , C12P9/00 , A61K35/612
CPC分类号： A61K35/612 , A61K9/0019 , A61K9/0053 , A61K31/047 , A61K31/122 , A61K31/685 , A61P27/02 , C12P9/00
摘要： The present invention provides compositions comprising phosphatidylcholine derived compounds carrying an omega-3 fatty acid for use in prophylaxis or therapy, particularly when administered systemically. This invention further relates to a modified krill oil composition enriched in LPC-DHA and LPC-EPA, methods of making and methods of using to treat neurological and ocular disorders.
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公开(公告)号：US10704011B2
公开(公告)日：2020-07-07
申请号：US14303835
申请日：2014-06-13
发明人： Nils Hoem , Asgeir Saebo
IPC分类号： A61K35/612 , C11B1/10 , A23G3/40
摘要： The present invention provides improved processes for extracting and preparing lipids from biological sources for use in pharmaceuticals, nutraceuticals and functional foods.
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公开(公告)号：US20200016214A1
公开(公告)日：2020-01-16
申请号：US16582618
申请日：2019-09-25
发明人： Finn Myhren , Nils Hoem , Håvard Thøgersen
IPC分类号： A61K35/612 , A61K31/683 , A61K31/685 , A61K31/122 , A61K31/20 , A61K31/201 , A61K31/575
摘要： The invention provides improved processes for extracting and preparing polar lipids (in particular, desirable phospholipids) from krill and other biological sources. The inventors have discovered processes through which it is possible to extract phospholipids to give high phospholipid content and a reduction of undesired components.
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公开(公告)号：US20190231744A1
公开(公告)日：2019-08-01
申请号：US16261933
申请日：2019-01-30
IPC分类号： A61K31/405 , A61K33/16 , A61K33/06 , A61K33/00 , A61K31/04 , A61K31/131 , A61K31/198 , A61K31/4172 , A61K31/401 , A23L33/18
CPC分类号： A61K31/405 , A23J3/341 , A23K10/22 , A23K20/147 , A23L33/10 , A23L33/18 , A23V2002/00 , A61K31/04 , A61K31/131 , A61K31/198 , A61K31/401 , A61K31/4172 , A61K33/00 , A61K33/06 , A61K33/16 , A61K35/60 , A61K35/612 , A61K38/012
摘要： The present invention provides marine protein hydrolysates for use in pharmaceuticals, nutraceuticals functional foods, foods, beverages, and animal feeds, as well as methods for making marine protein hydrolysates.
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公开(公告)号：US20180256650A1
公开(公告)日：2018-09-13
申请号：US15976130
申请日：2018-05-10
发明人： Inge Bruheim , Snorre Tilseth , Daniele Mancinelli
IPC分类号： A61K35/612 , A23L33/115 , A61K31/575 , A61K31/202 , A61K31/685 , A61K9/48 , A61K9/00 , A61K31/215
CPC分类号： A61K35/612 , A23L33/115 , A23V2002/00 , A61K9/0053 , A61K9/48 , A61K9/4825 , A61K9/4858 , A61K31/122 , A61K31/20 , A61K31/202 , A61K31/215 , A61K31/23 , A61K31/235 , A61K31/575 , A61K31/683 , A61K31/685 , A61K45/06 , C11B3/006 , A61K2300/00
摘要： This invention discloses new krill oil compositions characterized by having high amounts of phospholipids, astaxanthin esters and/or omega-3 contents. The krill oils are obtained from krill meal using supercritical fluid extraction in a two stage process. Stage 1 removes the neutral lipid by extracting with neat supercritical CO2 or CO2 plus approximately 5% of a co-solvent. Stage 2 extracts the actual krill oils by using supercritical CO2 in combination with approximately 20% ethanol. The krill oil materials obtained are compared with commercially available krill oil and found to be more bioeffective in a number of areas such as anti-inflammation, anti-oxidant effects, improving insulin resistances and improving blood lipid profile.
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7.发明授权公开(公告)号：US10028968B2
公开(公告)日：2018-07-24
申请号：US15260217
申请日：2016-09-08
发明人： Fotini Sampalis
IPC分类号： A61K31/23 , A61K31/661 , A61K9/48 , A61K31/683 , A61K31/685 , A61K31/122 , A61K9/00 , A61K35/612 , A23J7/00 , A23L33/115 , A23L33/00
CPC分类号： A61K31/661 , A23J7/00 , A23K20/158 , A23L33/115 , A23L33/30 , A23V2002/00 , A61K8/553 , A61K9/0053 , A61K9/48 , A61K31/122 , A61K31/353 , A61K31/6615 , A61K31/683 , A61K31/685 , A61K35/612 , A61K2800/522 , A61Q19/00 , C07D407/14 , C07F9/10 , C07F9/117 , C11B1/10 , Y10S514/824 , A23V2250/1846 , A23V2250/1852 , A23V2250/1848 , A23V2250/185 , A23V2250/1868 , A23V2250/187 , A23V2250/70
摘要： A phospholipid extract from a marine or aquatic biomass possesses therapeutic properties. The phospholipid extract comprises a variety of phospholipids, fatty acid, metals and a novel flavonoid.
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公开(公告)号：US20180193389A1
公开(公告)日：2018-07-12
申请号：US15915439
申请日：2018-03-08
发明人： Inge Bruheim , Snorre Tilseth , Daniele Mancinelli
IPC分类号： A61K35/612 , A23L33/115 , A61K31/575 , A61K31/202 , A61K31/685 , A61K9/48 , A61K9/00 , A61K31/215
CPC分类号： A61K35/612 , A23L33/115 , A23V2002/00 , A61K9/0053 , A61K9/48 , A61K9/4825 , A61K9/4858 , A61K31/122 , A61K31/20 , A61K31/202 , A61K31/215 , A61K31/23 , A61K31/235 , A61K31/575 , A61K31/683 , A61K31/685 , A61K45/06 , C11B3/006 , A61K2300/00
摘要： This invention discloses new krill oil compositions characterized by having high amounts of phospholipids, astaxanthin esters and/or omega-3 contents. The krill oils are obtained from krill meal using supercritical fluid extraction in a two stage process. Stage 1 removes the neutral lipid by extracting with neat supercritical CO2 or CO2 plus approximately 5% of a co-solvent. Stage 2 extracts the actual krill oils by using supercritical CO2 in combination with approximately 20% ethanol. The krill oil materials obtained are compared with commercially available krill oil and found to be more bioeffective in a number of areas such as anti-inflammation, anti-oxidant effects, improving insulin resistances and improving blood lipid profile.
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公开(公告)号：US20170246219A1
公开(公告)日：2017-08-31
申请号：US15589605
申请日：2017-05-08
发明人： Inge Bruheim , Snorre Tilseth , Daniele Mancinelli
IPC分类号： A61K35/612 , A61K9/00 , A23L33/115 , A61K31/215 , A61K31/202 , A61K31/575 , A61K9/48 , A61K31/685
CPC分类号： A61K35/612 , A23L33/115 , A23V2002/00 , A61K9/0053 , A61K9/48 , A61K9/4825 , A61K9/4858 , A61K31/122 , A61K31/20 , A61K31/202 , A61K31/215 , A61K31/23 , A61K31/235 , A61K31/575 , A61K31/683 , A61K31/685 , A61K45/06 , C11B3/006 , A61K2300/00
摘要： This invention discloses new krill oil compositions characterized by having high amounts of phospholipids, astaxanthin esters and/or omega-3 contents. The krill oils are obtained from krill meal using supercritical fluid extraction in a two stage process. Stage 1 removes the neutral lipid by extracting with neat supercritical CO2 or CO2 plus approximately 5% of a co-solvent. Stage 2 extracts the actual krill oils by using supercritical CO2 in combination with approximately 20% ethanol. The krill oil materials obtained are compared with commercially available krill oil and found to be more bioeffective in a number of areas such as anti-inflammation, anti-oxidant effects, improving insulin resistances and improving blood lipid profile.
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公开(公告)号：US09644170B2
公开(公告)日：2017-05-09
申请号：US15180439
申请日：2016-06-13
发明人： Inge Bruheim , Snorre Tilseth , Daniele Mancinelli
IPC分类号： C11B3/00 , A61K9/48 , A61K31/20 , A61K31/122 , A61K31/23 , A61K31/683 , A61K31/685 , A61K35/612 , A61K45/06 , A61K31/202 , A61K31/235 , A61K9/00
CPC分类号： A61K35/612 , A23L33/115 , A23V2002/00 , A61K9/0053 , A61K9/48 , A61K9/4825 , A61K9/4858 , A61K31/122 , A61K31/20 , A61K31/202 , A61K31/215 , A61K31/23 , A61K31/235 , A61K31/575 , A61K31/683 , A61K31/685 , A61K45/06 , C11B3/006 , A61K2300/00
摘要： This invention discloses new krill oil compositions characterized by having high amounts of phospholipids, astaxanthin esters and/or omega-3 contents. The krill oils are obtained from krill meal using supercritical fluid extraction in a two stage process. Stage 1 removes the neutral lipid by extracting with neat supercritical CO2 or CO2 plus approximately 5% of a co-solvent. Stage 2 extracts the actual krill oils by using supercritical CO2 in combination with approximately 20% ethanol. The krill oil materials obtained are compared with commercially available krill oil and found to be more bioeffective in a number of areas such as anti-inflammation, anti-oxidant effects, improving insulin resistances and improving blood lipid profile.
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