公开(公告)号：US09139814B2

公开(公告)日：2015-09-22

申请号：US13120141

申请日：2009-09-22

申请人： Victor-Alain Parent ,  Alain Garnier ,  Jacques P. Tremblay

发明人： Victor-Alain Parent ,  Alain Garnier ,  Jacques P. Tremblay

IPC分类号： C12N5/02 ,  C12N5/077 ,  A61K35/12

CPC分类号： C12N5/0658 ,  A61K35/12 ,  C12N2500/25 ,  C12N2500/84 ,  C12N2500/90 ,  C12N2500/99 ,  C12N2501/105 ,  C12N2501/11 ,  C12N2501/115 ,  C12N2501/135

摘要： This application relates to a serum-free culture medium that enables the proliferation of cell of the myogenic lineage while maintaining their ability to differentiate into functional muscle cells. Also contemplated herewith are method of culturing cells of the myogenic lineages and uses of the cultured cells for the treatment or the alleviation of symptoms of a muscular deficiencies.

摘要翻译： 本申请涉及一种无血清培养基，其能够在保持其分化为功能性肌肉细胞的能力的同时使肌源性谱系的细胞增殖。 本发明还考虑培养肌源性细胞的细胞和培养细胞的用途来治疗或减轻肌肉缺陷症状的方法。

公开(公告)号：US6161538A

公开(公告)日：2000-12-19

申请号：US72188

申请日：1998-05-05

申请人： Jean-Philippe Bonhomme ,  Jean-Claude Urgel ,  Alain Garnier

发明人： Jean-Philippe Bonhomme ,  Jean-Claude Urgel ,  Alain Garnier

IPC分类号： A62B18/04 ,  A62B18/08 ,  A62B17/04

CPC分类号： A62B18/04

摘要： The equipment has a helmet, a full face-cover fitted with fastenings for fixing it to the helmet, and with a coupling for connection to a breathable gas feed hose. It also has a flexible envelope extending the helmet and the face-cover downwards. For leakproof junction between the helmet, the face-cover and the envelope, a hoop is sealingly connected to the helmet. It has a lower branch which constitutes a closed bottom loop for receiving the envelope and a transverse branch having one side designed to sealingly receive the shell of the helmet and an opposite side which sealingly receives the face-cover. A plug rigidly fixed to the face-cover and placed in a vertical midplane of the face-cover, at the bottom thereof, engages a socket pivotally connected to the hoop. Lateral fasteners complete the connection.

摘要翻译： 设备有一个头盔，一个装有紧固件的全面罩，用于将其固定在头盔上，并具有连接到透气气体供给软管的联轴器。 它还有一个灵活的信封，将头盔和面罩向下延伸。 对于头盔，面罩和信封之间的防漏接头，环箍与头盔密封连接。 它具有下分支，其构成用于接收信封的封闭底部回路和具有设计成密封地容纳头盔壳体的一侧的横向分支和密封地接收面罩的相对侧。 刚性地固定在面罩上并且位于面罩的垂直中平面中的插头在其底部处接合枢轴连接到环的插座。 横向紧固件完成连接。

公开(公告)号：US20110250691A1

公开(公告)日：2011-10-13

申请号：US13120141

申请日：2009-09-22

申请人： Victor-Alain Parent ,  Alain Garnier ,  Jacques P. Tremblay

发明人： Victor-Alain Parent ,  Alain Garnier ,  Jacques P. Tremblay

IPC分类号： C12N5/077 ,  C12N5/0775

CPC分类号： C12N5/0658 ,  A61K35/12 ,  C12N2500/25 ,  C12N2500/84 ,  C12N2500/90 ,  C12N2500/99 ,  C12N2501/105 ,  C12N2501/11 ,  C12N2501/115 ,  C12N2501/135

摘要： This application relates to a serum-free culture medium that enables the proliferation of cell of the myogenic lineage while maintaining their ability to differentiate into functional muscle cells. Also contemplated herewith are method of culturing cells of the myogenic lineages and uses of the cultured cells for the treatment or the alleviation of symptoms of a muscular deficiencies.

摘要翻译： 本申请涉及一种无血清培养基，其能够在保持其分化为功能性肌肉细胞的能力的同时使肌源性谱系的细胞增殖。 本发明还考虑培养肌源性细胞的细胞和培养细胞的用途来治疗或减轻肌肉缺陷症状的方法。