公开(公告)号：US4797363A

公开(公告)日：1989-01-10

申请号：US885328

申请日：1986-07-14

申请人： Marius C. Teodorescu ,  Alexandre M. Gaspar

发明人： Marius C. Teodorescu ,  Alexandre M. Gaspar

IPC分类号： C12Q1/04 ,  C12Q1/70 ,  G01N33/53 ,  G01N33/554 ,  G01N33/569 ,  G01N33/58 ,  C12N7/00 ,  C12N7/02 ,  C12N13/00

CPC分类号： C12Q1/70 ,  C12Q1/04 ,  G01N33/53 ,  G01N33/554 ,  G01N33/56983 ,  G01N33/586 ,  Y10S436/802

摘要： Bacteriophages are employed as agents for recognition and identification of molecules and cellular materials, using their ability to recognize their bacterial host, by coating them with antibodies or by selecting them to perform in a manner analogous to antibodies. Visibility for identification is effected by incorporating a fluorescent agent, a radioisotope, a metal, an enzyme, or other staining material. The bacteriophage are prepared so as to bind to the molecular or cellular material through either the tail or head segment of the bacteriophage.

摘要翻译： 噬菌体用作识别和鉴定分子和细胞材料的试剂，使用它们识别其细菌宿主的能力，通过用抗体包被或通过选择它们以类似于抗体的方式进行。 用于鉴定的可见性通过掺入荧光剂，放射性同位素，金属，酶或其它染色材料来实现。 制备噬菌体以通过噬菌体的尾部或头部部分结合分子或细胞材料。