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公开(公告)号：US20130116222A1
公开(公告)日：2013-05-09
申请号：US13667632
申请日：2012-11-02
IPC分类号： A61K31/567
CPC分类号： A61K31/567 , A61K9/0014 , A61K9/7053 , A61K9/7061 , A61K31/57 , A61K47/12 , A61K47/20 , A61K47/32
摘要： A composition for transdermal delivery of a progestin for progestin hormone therapy is disclosed. Also disclosed is a transdermal delivery device comprising the composition. For progestin-only hormone therapy, the composition contains an anti-oxidant and does not contain an estrogen. For therapy involving a progestin and an estrogen, the composition contains the progestin, the estrogen and an additional anti-oxidant. Methods of improving the stability of progestin-containing compositions comprising oxidative agents are also disclosed. The methods comprise including one or more anti-oxidants in the compositions.
摘要翻译： 公开了用于孕激素治疗孕激素透皮递送的组合物。 还公开了包含该组合物的透皮递送装置。 对于仅孕激素治疗，该组合物含有抗氧化剂并且不含有雌激素。 对于涉及孕激素和雌激素的治疗，组合物含有孕激素，雌激素和另外的抗氧化剂。 还公开了改善含有孕激素的组合物包含氧化剂的稳定性的方法。 所述方法包括在组合物中包含一种或多种抗氧化剂。
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公开(公告)号：US09364487B2
公开(公告)日：2016-06-14
申请号：US13667632
申请日：2012-11-02
IPC分类号： A61K31/567 , A61K31/57 , A61K47/20 , A61K9/70 , A61K47/32
CPC分类号： A61K31/567 , A61K9/0014 , A61K9/7053 , A61K9/7061 , A61K31/57 , A61K47/12 , A61K47/20 , A61K47/32
摘要： A composition for transdermal delivery of a progestin for progestin hormone therapy is disclosed. Also disclosed is a transdermal delivery device comprising the composition. For progestin-only hormone therapy, the composition contains an anti-oxidant and does not contain an estrogen. For therapy involving a progestin and an estrogen, the composition contains the progestin, the estrogen and an additional anti-oxidant. Methods of improving the stability of progestin-containing compositions comprising oxidative agents are also disclosed. The methods comprise including one or more anti-oxidants in the compositions.
摘要翻译： 公开了用于孕激素治疗孕激素透皮递送的组合物。 还公开了包含该组合物的透皮递送装置。 对于仅孕激素治疗，该组合物含有抗氧化剂并且不含有雌激素。 对于涉及孕激素和雌激素的治疗，组合物含有孕激素，雌激素和另外的抗氧化剂。 还公开了改善含有孕激素的组合物包含氧化剂的稳定性的方法。 所述方法包括在组合物中包含一种或多种抗氧化剂。
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