Magnetizable composite microspheres based on a crosslinked organosilicon
polymer
    1.
    发明授权
    Magnetizable composite microspheres based on a crosslinked organosilicon polymer 失效
    基于交联有机硅聚合物的可磁化复合微结构

    公开(公告)号:US5178947A

    公开(公告)日:1993-01-12

    申请号:US634909

    申请日:1990-12-27

    摘要: Magnetizable composite microspheres comprising a core of a magnetizable filler distributed uniformly in a network of a polysilsesquioxane SiVi containing double bonds and a shell of a crosslinked organosilicon polymer derived from the hydrosilylation of an organohydrogenopolysiloxane SiH with the ethylenically unsaturated groups of the polysilsesquioxane. The magnetizable composite microspheres are obtained by dispersing an aqueous suspension of a magnetizable filler, not coated with a dispersing agent, in a solvent, dissolving an alkoxysilane or an alkoxysiloxane containing double bonds, polycondensing to a SiVi group-containing polysilsesquioxane SiVi, removing water, dissolving the organohydrogenopolysiloxane SiH polymer in the organic phase, crosslinking the mixture of polymers, removing water, separating the microspheres and, if appropriate, redispersing the microspheres in water. The magnetizable composite microspheres are preferably used as an active supports in biology.

    摘要翻译: 可磁化的复合微球,其包含均匀分布在含有双键的聚倍半硅氧烷SiVi的网络中的可磁化填料的芯和衍生自有机氢聚硅氧烷SiH与聚倍半硅氧烷的烯键式不饱和基团的氢化硅烷化的交联的有机硅聚合物的壳。 可磁化复合微球是通过将未涂覆分散剂的可磁化填料的水性悬浮液分散在溶剂中,将含有双键的烷氧基硅烷或烷氧基硅氧烷,缩聚反应分散在含SiVi的聚倍半硅氧烷SiVi中,除去水, 将有机氢聚硅氧烷SiH聚合物溶解在有机相中,交联聚合物的混合物,除去水,分离微球体,如果合适的话,将微球体再分散在水中。 可磁化复合微球优选用作生物学中的活性载体。