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公开(公告)号:US20110301079A1
公开(公告)日:2011-12-08
申请号:US12674620
申请日:2008-09-17
申请人: Donald J. Marsh , Antonello Pessi , Elisabetta Bianchi , Paolo Ingallinella , Andrea Peier , Alessandro Pocai
发明人: Donald J. Marsh , Antonello Pessi , Elisabetta Bianchi , Paolo Ingallinella , Andrea Peier , Alessandro Pocai
IPC分类号: A61K38/17 , C07K17/02 , A61P3/04 , A61P3/10 , A61P1/16 , A61P9/00 , A61P19/02 , A61P35/00 , A61P3/00 , A61P3/06 , C07K14/47 , A61P9/12
CPC分类号: C07K14/575
摘要: Neuromedin U receptor agonists for use in the treatment of metabolic disorders such as obesity and diabetes are disclosed. In particular, disclosed are neuromedin U receptor agonists that comprise neuromedin S (NMS).
摘要翻译: 公开了用于治疗代谢性疾病如肥胖症和糖尿病的神经介肽U受体激动剂。 具体地,公开了包含神经介肽S(NMS)的神经介肽U受体激动剂。
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公开(公告)号:US20080076136A1
公开(公告)日:2008-03-27
申请号:US11386249
申请日:2006-03-21
申请人: Stuart Bevan , Pamposh Ganju , Peter McIntyre , Ardem Patapoutian , Andrea Peier , Chuanzheng Song
发明人: Stuart Bevan , Pamposh Ganju , Peter McIntyre , Ardem Patapoutian , Andrea Peier , Chuanzheng Song
CPC分类号: C07K14/705 , C12Q1/6886 , G01N33/6872 , G01N33/6896 , G01N2500/00 , G01N2800/2842 , G01N2800/52
摘要: This invention provides novel genes and polypeptides of the transient receptor potential channel family, and use of these genes and polypeptides for the treatment of pain and identification of agents useful in the treatment of pain.
摘要翻译: 本发明提供瞬时受体潜在通道家族的新基因和多肽,以及这些基因和多肽用于治疗疼痛和鉴定用于治疗疼痛的药剂的用途。
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公开(公告)号:US07115414B2
公开(公告)日:2006-10-03
申请号:US10171319
申请日:2002-06-13
申请人: Stuart Bevan , Pamposh Ganju , Peter McIntyre , Ardem Patapoutian , Andrea Peier , Chuanzheng Song
发明人: Stuart Bevan , Pamposh Ganju , Peter McIntyre , Ardem Patapoutian , Andrea Peier , Chuanzheng Song
CPC分类号: C07K14/705 , C12Q1/6886 , G01N33/6872 , G01N33/6896 , G01N2500/00 , G01N2800/2842 , G01N2800/52
摘要: This invention provides novel genes and polypeptides of the VR family, identification of trkA+ pain specific genes expressed in the DRG, and use of these genes and polypeptides for the treatment of pain and identification of agents useful in the treatment of pain.
摘要翻译: 本发明提供VR家族的新基因和多肽,鉴定在DRG中表达的trkA u> sup>疼痛特异性基因,以及这些基因和多肽用于治疗疼痛和鉴定用于 治疗疼痛。
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公开(公告)号:US20060251648A1
公开(公告)日:2006-11-09
申请号:US11384955
申请日:2006-03-20
申请人: Stuart Bevan , Pamposh Ganju , Peter McIntyre , Ardem Patapoutian , Andrea Peier , Chuanzheng Song
发明人: Stuart Bevan , Pamposh Ganju , Peter McIntyre , Ardem Patapoutian , Andrea Peier , Chuanzheng Song
IPC分类号: G01N33/53 , C07H21/04 , A61K48/00 , C12P21/06 , A61K39/395 , C07K14/705 , A61K31/16
CPC分类号: C07K14/705 , C12Q1/6886 , G01N33/6872 , G01N33/6896 , G01N2500/00 , G01N2800/2842 , G01N2800/52
摘要: This invention provides novel genes and polypeptides of the transient receptor potential channel family, and use of these genes and polypeptides for the treatment of pain and identification of agents useful in the treatment of pain.
摘要翻译: 本发明提供瞬时受体潜在通道家族的新基因和多肽,以及这些基因和多肽用于治疗疼痛和鉴定用于治疗疼痛的药剂的用途。
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公开(公告)号:US07638601B2
公开(公告)日:2009-12-29
申请号:US11386249
申请日:2006-03-21
申请人: Stuart Bevan , Pamposh Ganju , Peter McIntyre , Ardem Patapoutian , Andrea Peier , Chuanzheng Song
发明人: Stuart Bevan , Pamposh Ganju , Peter McIntyre , Ardem Patapoutian , Andrea Peier , Chuanzheng Song
IPC分类号: C07K14/435 , A61K38/17
CPC分类号: C07K14/705 , C12Q1/6886 , G01N33/6872 , G01N33/6896 , G01N2500/00 , G01N2800/2842 , G01N2800/52
摘要: This invention provides novel genes and polypeptides of the transient receptor potential channel family, and use of these genes and polypeptides for the treatment of pain and identification of agents useful in the treatment of pain.
摘要翻译: 本发明提供瞬时受体潜在通道家族的新基因和多肽,以及这些基因和多肽用于治疗疼痛和鉴定用于治疗疼痛的药剂的用途。
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公开(公告)号:US07396910B2
公开(公告)日:2008-07-08
申请号:US11384955
申请日:2006-03-20
申请人: Stuart Bevan , Pamposh Ganju , Peter McIntyre , Ardem Patapoutian , Andrea Peier , Chuanzheng Song
发明人: Stuart Bevan , Pamposh Ganju , Peter McIntyre , Ardem Patapoutian , Andrea Peier , Chuanzheng Song
IPC分类号: C07K14/435 , A61K38/17
CPC分类号: C07K14/705 , C12Q1/6886 , G01N33/6872 , G01N33/6896 , G01N2500/00 , G01N2800/2842 , G01N2800/52
摘要: This invention provides novel genes and polypeptides of the transient receptor potential channel family, and use of these genes and polypeptides for the treatment of pain and identification of agents useful in the treatment of pain.
摘要翻译: 本发明提供瞬时受体潜在通道家族的新基因和多肽,以及这些基因和多肽用于治疗疼痛和鉴定用于治疗疼痛的药剂的用途。
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公开(公告)号:US20070244048A1
公开(公告)日:2007-10-18
申请号:US11724846
申请日:2007-03-16
申请人: Donald Marsh , Antonella Pessi , Maria Bednarek , Elisabetta Bianchi , Paolo Ingallinella , Andrea Peier
发明人: Donald Marsh , Antonella Pessi , Maria Bednarek , Elisabetta Bianchi , Paolo Ingallinella , Andrea Peier
CPC分类号: C07K14/575 , A61K38/00 , A61K47/543 , A61K47/554 , A61K47/60
摘要: Neuromedin U receptor agonists for use in the treatment of metabolic disorders such as obesity and diabetes are disclosed.
摘要翻译: 公开了用于治疗代谢性疾病如肥胖症和糖尿病的神经介肽U受体激动剂。
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