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公开(公告)号:US20080057536A1
公开(公告)日:2008-03-06
申请号:US11676414
申请日:2007-02-19
申请人: Andreas Szabados , Roberto Gerigk
发明人: Andreas Szabados , Roberto Gerigk
IPC分类号: G01N1/30
CPC分类号: G01N1/30
摘要: A fixative for fixing biological materials contains a depot agent, preferably a polyamine and especially hexamethylenetetramine, which reacts chemically with positively charged ions, especially H+ from an acid, while forming a fixative, where the fixative is an aldehyde and especially formaldehyde, which in turn reacts chemically with the biological material to be fixed in order to fix it and is consumed in doing so. By adjusting the pH of a solution containing the depot agent, a chemical equilibrium reaction occurs between the depot agent, fixative and biological material, so that just as much fixative is continuously formed as can be immediately consumed by the biological material. With that, the fixative, and especially the hazardous formaldehyde, cannot escape. Thus, an externally formaldehyde-free fixative that at the same time has the excellent fixative properties of formaldehyde is created.
摘要翻译: 用于固定生物材料的固定剂包含一种贮存剂,优选多胺,特别是六亚甲基四胺,其与形成固定剂的带正电荷的离子,特别是酸的H +化学反应,同时形成固定剂,其中固定剂是醛,特别是甲醛, 与要固定的生物材料化学反应以固定,并在这样做时消耗。 通过调节含有贮存剂的溶液的pH,在贮存剂,固定剂和生物材料之间发生化学平衡反应,使得与生物材料立即消耗的连续形成一样多的固定剂。 因此,固定剂,特别是有害甲醛,不能逃脱。 因此,产生了同时具有优异甲醛固定性质的外用无甲醛固定剂。
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公开(公告)号:US11099109B2
公开(公告)日:2021-08-24
申请号:US16077269
申请日:2017-02-10
申请人: Andreas Szabados
发明人: Andreas Szabados
IPC分类号: G01N1/30 , A61K45/06 , A61K31/496 , G01N1/36
摘要: A fixative for the preservation of organic tissue and cell aggregates, comprising a hydrophilic denaturant for structural change of the molecules of the organic tissue, a lipophobic solvent, in which said denaturant is dissolved, and an amphiphilic infiltration agent which is dissolved in the solvent for dissolving fats on the surface of the biological tissue in order to accelerate a penetration of the denaturant into the biological tissue.
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公开(公告)号:US07915007B2
公开(公告)日:2011-03-29
申请号:US11676414
申请日:2007-02-19
申请人: Andreas Szabados , Roberto Gerigk
发明人: Andreas Szabados , Roberto Gerigk
CPC分类号: G01N1/30
摘要: A fixative for fixing biological materials contains a depot agent, preferably a polyamine and especially hexamethylenetetramine, which reacts chemically with positively charged ions, especially H+ from an acid, while forming a fixative, where the fixative is an aldehyde and especially formaldehyde, which in turn reacts chemically with the biological material to be fixed in order to fix it and is consumed in doing so. By adjusting the pH of a solution containing the depot agent, a chemical equilibrium reaction occurs between the depot agent, fixative and biological material, so that just as much fixative is continuously formed as can be immediately consumed by the biological material. With that, the fixative, and especially the hazardous formaldehyde, cannot escape. Thus, an externally formaldehyde-free fixative that at the same time has the excellent fixative properties of formaldehyde is created.
摘要翻译: 用于固定生物材料的固定剂包含一种贮存剂,优选多胺,特别是六亚甲基四胺,其与形成固定剂的带正电荷的离子,特别是酸的H +化学反应,同时形成固定剂,其中固定剂是醛,特别是甲醛, 与要固定的生物材料化学反应以固定,并在这样做时消耗。 通过调节含有贮存剂的溶液的pH,在贮存剂,固定剂和生物材料之间发生化学平衡反应,使得与生物材料立即消耗的连续形成一样多的固定剂。 因此,固定剂,特别是有害甲醛,不能逃脱。 因此,产生了同时具有优异甲醛固定性质的外用无甲醛固定剂。
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公开(公告)号:US5104533A
公开(公告)日:1992-04-14
申请号:US445612
申请日:1990-01-05
申请人: Andreas Szabados
发明人: Andreas Szabados
CPC分类号: B01L3/5021 , B01D29/05 , B01D36/001
摘要: A filtration unit, especially for medical, microbiological, biochemical, immunological or molecular biology specimens. The filtration unit includes a specimen-receiving vessel (12), a filtrate vessel (16) and a filter member (22) containing a filter element (24, 26) arranged between the specimen-receiving vessel and filtrate vessel. In order to obtain an automatic pressure compensation in a closed system the filtrate vessel inner space (28) is connected with the specimen-receiving vessel inner space (30) by at least one pressure compensation channel (50) bypassing the filtration liquid (48). The pressure compensation channel extends axially along a side wall of the specimen-receiving vessel and connects a first discharge point in the filtrate vessel inner space above the maximum filtrate level with a second discharge point in the specimen-receiving vessel inner space above the maximum filtration fluid level while bypassing the filtration unit. The channel ends in the region of a cap for opening into the inner space of the specimen-receiving vessel.
摘要翻译: PCT No.PCT / EP88 / 00614 Sec。 371日期1990年2月22日 102(e)日期1990年2月22日PCT提交1988年7月8日PCT公布。 出版物WO89 / 00288 日期1989年1月12日。一个过滤单元,特别适用于医学,微生物,生物化学,免疫学或分子生物学标本。 过滤单元包括试样接收容器(12),滤液容器(16)和过滤构件(22),过滤构件(22)包含布置在试样容纳容器和滤液容器之间的过滤元件(24,26)。 为了在封闭系统中获得自动压力补偿,滤液容器内部空间(28)通过绕过过滤液体(48)的至少一个压力补偿通道(50)与试样接收容器内部空间(30)连接, 。 压力补偿通道沿着试样接收容器的侧壁轴向延伸,将滤液容器内部空间中的最大滤液水平之上的第一排放点与最大过滤面之上的样品接收容器内部空间中的第二排放点相连接 旁路过滤单元时的液位。 通道在盖的区域中终止,用于打开到样本容纳容器的内部空间。
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公开(公告)号:US10955230B2
公开(公告)日:2021-03-23
申请号:US16499679
申请日:2018-03-27
申请人: Andreas Szabados
发明人: Andreas Szabados
IPC分类号: F42B33/10
摘要: A device (2) for pulling a cartridge case (4) in a pulling direction (10) out of an axial bore of a die (6) which, as seen from the axial bore, comprises a male thread (20) on the outside to hold the die (6) in a reloading press is provided. The device (2) comprises: a support plate (12) for holding the die (6) aligned with its axial bore in the pulling direction 10) and secured against a movement in the pulling direction (10) in a die bore (18) a lifting plate (14) arranged at a distance (16) before the support plate (12) as seen in the pulling direction (10), comprising a pulling element (24) with retaining members aligned against the pulling direction (10), wherein the retaining members are arranged in such a way to hold the cartridge case (4) at an end of the pulling element (24) opposite the lifting plate (14), and drive members (32, 34) for driving the support plate (12) and the lifting plate (14) apart in and/or against the pulling direction (10).
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公开(公告)号:US20190033180A1
公开(公告)日:2019-01-31
申请号:US16077269
申请日:2017-02-10
申请人: Andreas Szabados
发明人: Andreas Szabados
IPC分类号: G01N1/30 , A61K31/496 , A61K45/06
摘要: A fixative for the preservation of organic tissue and cell aggregates, comprising a hydrophilic denaturant for structural change of the molecules of the organic tissue, a lipophobic solvent, in which said denaturant is dissolved, and an amphiphilic infiltration agent which is dissolved in the solvent for dissolving fats on the surface of the biological tissue in order to accelerate a penetration of the denaturant into the biological tissue.
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公开(公告)号:US4678559A
公开(公告)日:1987-07-07
申请号:US804348
申请日:1985-12-03
申请人: Andreas Szabados
发明人: Andreas Szabados
CPC分类号: A61B10/0038 , G01N1/28
摘要: A sample-taking vessel 10 for pasty sample material, especially faeces, to be distributed in suspension fluid comprises a sample-taking cup 12 fitted on a vessel lid 14 and open towards the vessel bottom. The vessel bottom is formed with an elevation 28 which is shaped complementarily to the sample-taking cup 12. The cup wall 42 is provided at least in zones with sieve openings 44 out of which the sample material is forced and finely distributed in the suspension fluid 46 in the closing of the sample-taking vessel 10 with the aid of the vessel lid 14.
摘要翻译: 用于糊状样品材料(特别是粪便)的采样容器10分布在悬浮液中包括装在容器盖14上并朝向容器底部开口的取样杯12。 容器底部形成有与取样杯12互补形状的高度28.杯壁42至少设置有筛孔44的区域,其中样品材料被强制并精细地分布在悬浮液中 46在借助于容器盖14关闭取样容器10中。
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公开(公告)号:US4201385A
公开(公告)日:1980-05-06
申请号:US845380
申请日:1977-10-25
申请人: Andreas Szabados
发明人: Andreas Szabados
摘要: A target apparatus which comprises a container and butt walls within it, the container and butt walls carrying noise deadening material whereby the target apparatus may be used close to inhabited areas or even indoors without disturbing other people owing to the noise.
摘要翻译: 一种目标装置,其包括容器和其内的对接壁,容器和对接壁承载噪声消音材料,由此目标装置可以靠近居住区域甚至室内使用,而不会由于噪声而扰乱其他人。
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